Anders Vik

Image of Anders Vik
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Phone +47-22857451
Room Ø195/Ø198 Fysikkbygningen
Username
Visiting address Avdeling for farmasøytisk kjemi Farmasibygningen Sem Sælands vei 3 0371 OSLO
Postal address Postboks 1068 Blindern 0316 OSLO

Academic Interests

Medicinal chemistry, synthetic organic chemistry, lipid chemistry, natural product synthesis and method development in synthetic organic chemistry.

Teaching

Higher education and employment history

  • Associate professor, 2011 - date. Dept. of pharmaceutical chemistry, School of pharmacy, University of Oslo.
  • Post doctoral research fellow, Dept. of pharmaceutical chemistry, School of pharmacy, University of Oslo 2009-2011
  • Scientist, Invitrogen Dynal AS, Lillestrøm, June 2007-November 2008
  • Scientist, Synthetica AS, Oslo, March 2007-June 2007
  • Ph.D., Dept. of Chemistry, University of Oslo (2007)
  • M. Sc., Norwegian University of Science and Technology (2003)

 

Tags: Life Science, Medicinal chemistry, Organic chemistry, Chemistry, Lipids, Polyunsaturated fatty acids, Pharmaceutical chemistry, Natural product synthesis

Publications

  • Primdahl, Karoline Gangestad; Tungen, Jørn Eivind; De Souza, Patricia R; Colas, Romain A.; Dalli, Jesmond; Hansen, Trond Vidar & Vik, Anders (2017). Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA. Organic and biomolecular chemistry.  ISSN 1477-0520.  15, s 8606- 8613 . doi: 10.1039/c7ob02113e
  • Van Gansbeke, Koen; Solum, Eirik Johansson; Liekens, Sandra; Vik, Anders & Hansen, Trond Vidar (2017). Regioselective monoalkylation of 17β-estradiol for the synthesis of cytotoxic estrogens. Steroids.  ISSN 0039-128X.  124, s 54- 59 . doi: 10.1016/j.steroids.2017.06.001
  • Vik, Anders; Dalli, Jesmond & Hansen, Trond Vidar (2017). Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid. Bioorganic & Medicinal Chemistry Letters.  ISSN 0960-894X.  27(11), s 2259- 2266 . doi: 10.1016/j.bmcl.2017.03.079
  • Kaupang, Åsmund; Kase, Eili Tranheim; Vo, Cecilie Xuan Trang; Amundsen, Marthe; Vik, Anders & Hansen, Trond Vidar (2016). Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ. Bioorganic & Medicinal Chemistry.  ISSN 0968-0896.  24(2), s 247- 260 . doi: 10.1016/j.bmc.2015.12.012
  • Primdahl, Karoline Gangestad; Aursnes, Marius; Walker, Mary E.; Colas, Romain A.; Serhan, Charles N.; Dalli, Jesmond; Hansen, Trond Vidar & Vik, Anders (2016). Synthesis of 13(R)‐Hydroxy‐7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R‐HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. Journal of natural products.  ISSN 0163-3864.  79, s 2693- 2702 . doi: 10.1021/acs.jnatprod.6b00634 Show summary
  • Primdahl, Karoline Gangestad; Stenstrøm, Yngve H.; Hansen, Trond Vidar & Vik, Anders (2016). Synthesis of 5-(S)-HETE, 5-(S)-HEPE and (+)-zooxanthellactone: Three hydroxylated polyunsaturated fatty acid metabolites. Chemistry and Physics of Lipids.  ISSN 0009-3084.  196, s 1- 4 . doi: 10.1016/j.chemphyslip.2015.12.005
  • Tungen, Jørn Eivind; Aursnes, Marius & Vik, Anders (2016). Synthesis of Ieodomycin D. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry.  ISSN 0936-5214.  27(17), s 2497- 2499 . doi: 10.1055/s-0035-1562776
  • Vik, Anders & Hansen, Trond Vidar (2016). Fatty Acids and their Derivatives, In Alexandros L. Zografos (ed.),  From Biosynthesis to Total Synthesis: Strategies and Tactics for Natural Products.  John Wiley & Sons.  ISBN 978-1-118-75173-2.  3.  s 130 - 161
  • Kaupang, Åsmund; Hildonen, Siri; Halvorsen, Trine Grønhaug; Mortén, Magnus; Vik, Anders & Hansen, Trond Vidar (2015). Involvement of covalent interactions in the mode of action of PPARβ/δ antagonists. RSC Advances.  ISSN 2046-2069.  5(93), s 76483- 76490 . doi: 10.1039/c5ra15707b
  • Primdahl, Karoline Gangestad; Tungen, Jørn Eivind; Aursnes, Marius; Hansen, Trond Vidar & Vik, Anders (2015). An efficient total synthesis of leukotriene B4. Organic and biomolecular chemistry.  ISSN 1477-0520.  13(19), s 5412- 5417 . doi: 10.1039/c5ob00473j
  • Solum, Eirik Johansson; Akselsen, Øyvind Wilhelm; Vik, Anders & Hansen, Trond Vidar (2015). Synthesis and pharmacological effects of the anti-cancer agent 2-methoxyestradiol. Current pharmaceutical design.  ISSN 1381-6128.  21(38), s 5453- 5466 . doi: 10.2174/1381612821666151002112511
  • Solum, Eirik Johansson; Cheng, Jing-Jy; Sylte, Ingebrigt; Vik, Anders & Hansen, Trond Vidar (2015). Synthesis, biological evaluation and molecular modeling of new analogs of the anti-cancer agent 2-methoxyestradiol: potent inhibitors of angiogenesis. RSC Advances.  ISSN 2046-2069.  5(41), s 32497- 32504 . doi: 10.1039/c5ra03570h Full text in Research Archive.
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders; Colas, Romain; Cheng, Chien-Yee C.; Dalli, Jesmond; Serhan, Charles N. & Hansen, Trond Vidar (2014). Total synthesis of the lipid mediator PD1n-3 DPA: Configurational assignments and anti-inflammatory and pro-resolving actions. Journal of natural products (Print).  ISSN 0163-3864.  77(4), s 910- 916 . doi: 10.1021/np4009865
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders; Dalli, J. & Hansen, Trond Vidar (2014). Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator. Organic and biomolecular chemistry.  ISSN 1477-0520.  12(3), s 432- 437 . doi: 10.1039/c3ob41902a
  • Jakobsen, Martin Gjerde; Vik, Anders & Hansen, Trond Vidar (2014). Stereoselective synthesis of zooxanthellactone. Tetrahedron Letters.  ISSN 0040-4039.  55(17), s 2842- 2844 . doi: 10.1016/j.tetlet.2014.03.085
  • Solum, Eirik Johansson; Cheng, Jing-Jy; Sørvik, Irene Beate; Paulsen, Ragnhild Elisabeth; Vik, Anders & Hansen, Trond Vidar (2014). Synthesis and biological evaluations of new analogs of 2-methoxyestradiol: Inhibitors of tubulin and angiogenesis. European Journal of Medicinal Chemistry.  ISSN 0223-5234.  85, s 391- 398 . doi: 10.1016/j.ejmech.2014.08.002
  • Solum, Eirik Johansson; Vik, Anders & Hansen, Trond Vidar (2014). Synthesis, cytotoxic effects and tubulin polymerization inhibition of 1,4-disubstituted 1,2,3-triazole analogs of 2-methoxyestradiol. Steroids.  ISSN 0039-128X.  87, s 46- 53 . doi: 10.1016/j.steroids.2014.05.020
  • Tungen, Jørn Eivind; Aursnes, Marius; Vik, Anders; Ramon, Sesquile; Colas, Romain A.; Dalli, Jesmond; Serhan, Charles N. & Hansen, Trond Vidar (2014). Synthesis and anti-inflammatory and pro-resolving activities of 22-OH-PD1, a monohydroxylated metabolite of protectin D1. Journal of natural products (Print).  ISSN 0163-3864.  77(10), s 2241- 2247 . doi: 10.1021/np500498j
  • Mohamed, Yasser Mahmoud Ali; Vik, Anders; Hofer, Tim; Andersen, Jeanette hammer & Hansen, Trond Vidar (2013). Polyunsaturated fatty acid-derived chromones exhibiting potent antioxidant activity. Chemistry and Physics of Lipids.  ISSN 0009-3084.  170, s 41- 45 . doi: 10.1016/j.chemphyslip.2013.03.003
  • Jakobsen, Martin Gjerde; Vik, Anders & Hansen, Trond Vidar (2012). Concise syntheses of three ω-3 polyunsaturated fatty acids. Tetrahedron Letters.  ISSN 0040-4039.  53(44), s 5837- 5839 . doi: 10.1016/j.tetlet.2012.08.009
  • Vik, Anders & Hansen, Trond Vidar (2011). Synthesis of a polyunsaturated amino ketone isolated from a Guangxi sponge of the genus Haliclona. Tetrahedron Letters.  ISSN 0040-4039.  52(10), s 1060- 1061 . doi: 10.1016/j.tetlet.2010.12.089
  • Vik, Anders; Hansen, Trond Vidar; Holmeide, Anne Kristin & Skattebøl, Lars (2010). Synthesis of juniperonic acid. Tetrahedron Letters.  ISSN 0040-4039.  51(21), s 2852- 2854 . doi: 10.1016/j.tetlet.2010.03.085 Show summary
  • Vik, Anders; Proszenyak, Agnes; Vermeersch, Marieke; Cos, Paul; Maes, Louis & Gundersen, Lise-Lotte (2009). Screening of Agelasine D and Analogs for Inhibitory Activity against Pathogenic Protozoa; Identification of Hits for Visceral Leishmaniasis and Chagas Disease. Molecules.  ISSN 1420-3049.  14(1), s 279- 288 . doi: 10.3390/molecules14010279 Show summary
  • Sjögren, Martin; Dahlström, Mia; Hedner, Erik; Jonsson, Per R.; Vik, Anders; Gundersen, Lise-Lotte & Bohlin, Lars (2008). Antifouling activity of the sponge metabolite agelasine D and synthesized analogs on Balanus improvisus. Biofouling (Print).  ISSN 0892-7014.  24(4), s 251- 258 . doi: 10.1080/08927010802072753 Show summary
  • Vik, Anders & Gundersen, Lise-Lotte (2007). Synthetic studies directed towards asmarines; construction of the tetrahydrodiazepinopurine moiety by ring closing metathesis. Tetrahedron Letters.  ISSN 0040-4039.  48, s 1931- 1934 . doi: 10.1016/j.tetlet.2007.01.090
  • Vik, Anders; Hedner, Erik; Charnock, Colin; Tangen, Linda; tangen, Linda W; Samuelsen, Ørjan; Larsson, Rolf; Bohlin, Lars & Gundersen, Lise-Lotte (2007). Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs. Bioorganic & Medicinal Chemistry.  ISSN 0968-0896.  15 . doi: 10.1016/j.bmc.2007.03.08
  • Vik, Anders; James, A & Gundersen, Lise-Lotte (2007). Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro. Planta Medica.  ISSN 0032-0943.  73, s 1410- 1412 . doi: 10.1055/s-2007-990238
  • Vik, Anders; Hedner, Erik; Charnock, Colin; Samuelsen, Ørjan; Larsson, Rolf; Gundersen, Lise-Lotte & Bohlin, Lars (2006). (+)-agelasine D: Improved synthesis and evaluation of antibacterial and cytotoxic activities. Journal of natural products (Print).  ISSN 0163-3864.  69
  • Bakkestuen, Anne Kristin Vibstad; Gundersen, Lise-Lotte; Petersen, Dirk; Utenova, Bibigul & Vik, Anders (2005). Synthesis and Antimycobacterial Activity of Agelasine E and Analogs. Organic and biomolecular chemistry.  ISSN 1477-0520.  3, s 1025- 1033
  • Sundby, Eirik; Vik, Anders; Holt, Jarle & Anthonsen, Thorleif (2004). Chemoenzymatic Synthesis of (2S)- and (2R)-2-(1,3-Dithian-2-ylmethyl)oxirane. European Journal of Organic Chemistry.  ISSN 1434-193X.  (6), s 1239- 1243
  • Sundby, Eirik; Holt, Jarle; Vik, Anders & Anthonsen, Thorleif (2004). Chemoenzymatic synthesis of (2S)- and (2R)-2-(1,3-dithian-2-ylmethyl)oxirane. European Journal of Organic Chemistry.  ISSN 1434-193X.  (6), s 1239- 1243 Show summary

View all works in Cristin

  • al-Kazaale, Nora; Solum, Eirik Johansson; Vik, Anders & Hansen, Trond Vidar (2017). Synthesis of New Analogs of 2-Methoxyestradiol as Potential Anticancer Agents.
  • Aursnes, Marius; Primdahl, Karoline Gangestad; Hansen, Trond Vidar & Vik, Anders (2017). Synthetic Studies Towards the 13-series Resolvin Member RvT3.
  • Primdahl, Karoline Gangestad; Aursnes, Marius; Walker, Mary E.; Colas, Romain A.; Serhan, Charles Nicholas; Dalli, Jesmond; Hansen, Trond Vidar & Vik, Anders (2017). Biosynthetic Studies of RvT1-4: A Novel Class of Specialized Pro-resolving and Anti-inflammatory Mediators.
  • Primdahl, Karoline Gangestad; Aursnes, Marius; Walker, Mary E.; Serhan, Charles Nicholas; Dalli, Jesmond; Hansen, Trond Vidar & Vik, Anders (2017). Synthesis of 13R‑HDPA and Its Biosynthetic Conversion to the 13-Series Resolvins.
  • Vik, Anders; Aursnes, Marius; Tungen, Jørn Eivind; Colas, Romain A.; Cheng, Chien-Yee C.; Dalli, Jesmond; Serhan, Charles Nicholas & Hansen, Trond Vidar (2017). Biosynthesis and the Anti-inflammatory and Pro-resolving Effects of the Novel Lipid Mediator Protectin D1n-3 DPA.
  • Kristianslund, Renate; Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders & Hansen, Trond Vidar (2016). Organocatalytic enantioselective iodolactonization of allenoic acids.
  • Primdahl, Karoline Gangestad; Aursnes, Marius; Walker, Mary E.; Colas, Romain A.; Dalli, Jesmond; Hansen, Trond Vidar & Vik, Anders (2016). Synthesis of 13-(R)-HDPA.
  • Primdahl, Karoline Gangestad; Tungen, Jørn Eivind; Aursnes, Marius; Hansen, Trond Vidar & Vik, Anders (2016). Total Synthesis of Leukotriene B4.
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders & Hansen, Trond Vidar (2015). Synthesis, Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Mono-Hydroxylated Metabolite of Protectin D1.
  • Kaupang, Åsmund; Hildonen, Siri; Halvorsen, Trine Grønhaug; Mortén, Magnus; Vik, Anders & Hansen, Trond Vidar (2015). Investigations on the covalent antagonistic modulation of PPARβ/δ.
  • Primdahl, Karoline Gangestad; Aursnes, Marius; Tungen, Jørn Eivind; Hansen, Trond Vidar & Vik, Anders (2015). Total synthesis of leukotriene B4.
  • Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar Martin; Sylte, Ingebrigt; Hansen, Trond Vidar & Nebb, Hilde Irene (2015). Anti-diabetic activity from marine lipids: new anti-diabetic drugs.
  • Vik, Anders (2015). Synthesis of Specialized Pro-resolving Lipid Mediators.
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders & Hansen, Trond Vidar (2013). Total synthesis of Protectin D1.
  • Kaupang, Åsmund; Laitinen, Tuomo; Vik, Anders; Poso, Antti & Hansen, Trond Vidar (2013). Molecular modelling and synthesis of putative high-affinity inhibitors of hPPARδ.
  • Solum, Eirik Johansson; Vik, Anders & Hansen, Trond Vidar (2013). Synthesis of analogs of 2-methoxyestradiol as potent anticancer agents.
  • Solum, Eirik Johansson; Vik, Anders & Hansen, Trond Vidar (2013). Synthesis of analogs of 2-methoxyestradiol as potential anticancer agents.
  • Aursnes, Marius; Vik, Anders & Hansen, Trond Vidar (2012). Synthetic Studies Towards Protectin D1.
  • Mohamed, Yasser Mahmoud Ali; Vik, Anders & Hansen, Trond Vidar (2012). Synthesis of lipophilic antioxidants.
  • Gundersen, Lise-Lotte; Kania, Jindrich; Odden, Hege Hortemo; Proszenyak, Agnes & Vik, Anders (2011). Synthesis directed towards Agelasines and Asmarines; Marine Antibiotics.
  • Jakobsen, Martin Gjerde; Vik, Anders & Hansen, Trond Vidar (2011). Synthetic Studies Towards Resolvin D1.
  • Vik, Anders; Hansen, Trond Vidar; Skattebøl, Lars & Holmeide, Anne Kristin (2011). Synthesis of juniperonic acid.
  • Vik, Anders; Hansen, Trond Vidar; Holmeide, Anne Kristin & Skattebøl, Lars (2010). Synthesis of juniperonic acid.
  • Bakkestuen, Anne Kristin; Charnock, Colin; Cos, Paul; Gundersen, Lise-Lotte; Maes, Louis; Proszenyak, Agnes; Roggen, Heidi; Utenova, Bibigul t.; Vermeersch, Marieke & Vik, Anders (2009). Synthetic studies directed towards antimicrobial agelasines.
  • Sjögren, Martin; Dahlström, Mia; Göransson, Ulf; Hedner, Erik; Jonsson, Per R.; Bohlin, Lars; Vik, Anders & Gundersen, Lise-Lotte (2009). Antifouling activity of the sponge metabolite agelasine D.
  • Vik, Anders; Proszenyak, Agnes; Vermeersch, Marieke; Cos, Paul; Maes, Louis & Gundersen, Lise-Lotte (2009). Screening of agelasine analogs; Identification of hits for visceral leishmaniasis and Chagas disease.
  • Vik, Anders; James, Anthony & Gundersen, Lise-Lotte (2008). Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro.
  • Vik, Anders & Gundersen, Lise-Lotte (2007). Synthetic studies directed towards Asmarines: Construction of the 7-membered ring by RCM.
  • Vik, Anders & Gundersen, Lise-Lotte (2007). Synthetic studies directed towards Asmarines: Construction of the 7-membered ring by RCM.
  • Vik, Anders & Gundersen, Lise-Lotte (2007). Synthetic studies directed towards bioactive purine-containing natural products and analogs.
  • Vik, Anders; Hedner, Erik; Charnock, Colin; Larsson, Rolf; Gundersen, Lise-Lotte & Bohlin, Lars (2006). Synthesis of agelasine and agelasimine analogs and evaluation of antibacterial and cytotoxic effects.
  • Vik, Anders; Hedner, Erik; Charnock, Colin; Samuelsen, Ørjan; Larsson, Rolf; Gundersen, Lise-Lotte & Bohlin, Lars (2006). Improved Synthesis of Agelasine D and Evaluation of Antibacterial and Cytotoxic Activity.
  • Vik, Anders; Hedner, Erik; Charnock, Collin; Larsson, Rolf; Gundersen, Lise-Lotte & Bohlin, Lars (2006). Synthesis of agelasine and agelasimine analogs and evaluation of antibacterial and cytotoxic effects.
  • Vik, Anders; Bakkestuen, Anne Kristin; Gundersen, Lise-Lotte & Utenova, Bibigul t. (2005). Synthesis and Bioactivities of Agelasines and Analogs.
  • Vik, Anders & Gundersen, Lise-Lotte (2005). Synthesis and Bioactivities if Agelasines and Analogs.
  • Vik, Anders; Bakkestuen, Anne Kristin Vibstad; Gundersen, Lise-Lotte & Utenova, Bibigul (2004). Synthesis of Antimycobacterial Agelasine Analogs.
  • Bakkestuen, Anne Kristin; Gundersen, Lise-Lotte; Utenova, Bibigul t. & Vik, Anders (2004). Synthesis and Antimycobacterial Activity of Agelasines and Analogs.
  • Gundersen, Lise-Lotte; Bakkestuen, Anne Kristin; Brændvang, Morten & Vik, Anders (2004). Synthesis of Novel Antimycobacterial Purine Derivatives. Potential Drugs against Tuberculosis, a Major Cause of Death among Miners.

View all works in Cristin

Published Nov. 3, 2010 3:45 PM - Last modified Apr. 15, 2015 9:50 AM