Jørn Eivind Tungen

Image of Jørn Eivind Tungen
Norwegian version of this page
Phone +47-22857449
Mobile phone +47-95006535
Room Ø192 Fysikkbygningen
Username
Visiting address Sem Sælands vei 3 Farmasibygningen 0371 OSLO
Postal address Postboks 1068 Blindern 0316 OSLO

Academic Interests

Organic chemistry, synthesis, medicinal chemistry, catalysis and process chemistry.

Teaching

Teaching lab classes in:

Bakgrunn

Civil engineer in organic chemistry, NTNU (Norwegian University of Science and Technology), 2011.

 

Tags: Medicinal chemistry

Publications

  • Kristianslund, Renate; Aursnes, Marius; Tungen, Jørn Eivind; Görbitz, Carl Henrik & Hansen, Trond Vidar (2018). Synthesis, Biological Investigation, and Structural Revision of Sielboldianin A. Journal of natural products.  ISSN 0163-3864.  81, s 1007- 1013 . doi: 10.1021/acs.jnatprod.8b00020 Show summary
  • Sæther, Thomas; Paulsen, Steinar M; Tungen, Jørn Eivind; Vik, Anders; Aursnes, Marius; Holen, Torgeir; Hansen, Trond Vidar & Nebb, Hilde Irene (2018). Synthesis and biological evaluations of marine oxohexadecenoic acids: PPARα/γ dual agonism and anti-diabetic target gene effects. European Journal of Medicinal Chemistry.  ISSN 0223-5234.  155, s 736- 753 . doi: 10.1016/j.ejmech.2018.06.034 Show summary
  • Primdahl, Karoline Gangestad; Tungen, Jørn Eivind; De Souza, Patricia R; Colas, Romain A.; Dalli, Jesmond; Hansen, Trond Vidar & Vik, Anders (2017). Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA. Organic and biomolecular chemistry.  ISSN 1477-0520.  15(40), s 8606- 8613 . doi: 10.1039/c7ob02113e
  • Aursnes, Marius; Tungen, Jørn Eivind & Hansen, Trond Vidar (2016). Enantioselective Organocatalyzed Bromolactonizations: Applications in Natural Product Synthesis. Journal of Organic Chemistry.  ISSN 0022-3263.  81, s 8287- 8295 . doi: 10.1021/acs.joc.6b01375 Show summary
  • Kristianslund, Renate; Aursnes, Marius; Tungen, Jørn Eivind & Hansen, Trond Vidar (2016). Squaramide catalyzed enantioselective iodolactonization of allenoic acids. Tetrahedron Letters.  ISSN 0040-4039.  57(47), s 5232- 5236 . doi: 10.1016/j.tetlet.2016.10.035 Show summary
  • Ramon, Sesquile; Dalli, Jesmond; Sanger, Julia M.; Winkler, Jeremy W.; Aursnes, Marius; Tungen, Jørn Eivind; Hansen, Trond Vidar & Serhan, Charles N. (2016). The Protectin PCTR1 Is Produced by Human M2 Macrophages and Enhances Resolution of Infectious Inflammation. American Journal of Pathology.  ISSN 0002-9440.  186(4), s 962- 973 . doi: 10.1016/j.ajpath.2015.12.012 Show summary
  • Tian, Yutao; Aursnes, Marius; Hansen, Trond Vidar; Tungen, Jørn Eivind; Galpin, Jason; Leisle, Lilia; Ahern, Christopher A.; Xu, Rong; Heinemann, Stefan H. & Hoshi, Toshinori (2016). Atomic determinants of BK channel activation by polyunsaturated fatty acids. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  113(48), s 13905- 13910 . doi: 10.1073/pnas.1615562113
  • Tungen, Jørn Eivind; Aursnes, Marius & Vik, Anders (2016). Synthesis of Ieodomycin D. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry.  ISSN 0936-5214.  27(17), s 2497- 2499 . doi: 10.1055/s-0035-1562776
  • Aursnes, Marius; Tungen, Jørn Eivind; Colas, Romain A.; Vlasakov, Iliyan; Dalli, Jesmond; Serhan, Charles N. & Hansen, Trond Vidar (2015). Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages. Journal of natural products.  ISSN 0163-3864.  78(12), s 2924- 2931 . doi: 10.1021/acs.jnatprod.5b00574
  • Nolsøe, Jens Mortansson J; Aursnes, Marius; Tungen, Jørn Eivind & Hansen, Trond Vidar (2015). Dienals derived from pyridinium salts and their subsequent application in natural product synthesis. Journal of Organic Chemistry.  ISSN 0022-3263.  80(11), s 5377- 5385 . doi: 10.1021/acs.joc.5b00879
  • Primdahl, Karoline Gangestad; Tungen, Jørn Eivind; Aursnes, Marius; Hansen, Trond Vidar & Vik, Anders (2015). An efficient total synthesis of leukotriene B4. Organic and biomolecular chemistry.  ISSN 1477-0520.  13(19), s 5412- 5417 . doi: 10.1039/c5ob00473j
  • Tungen, Jørn Eivind; Aursnes, Marius & Hansen, Trond Vidar (2015). Stereoselective synthesis of maresin 1. Tetrahedron Letters.  ISSN 0040-4039.  56(14), s 1843- 1846 . doi: 10.1016/j.tetlet.2015.02.080 Show summary
  • Aaseng, Jon Erik; Iqbal, Naseem; Tungen, Jørn Eivind; Sperger, Christian & Fiksdahl, Anne (2014). 3-Halotetrahydropyran-4-one derivatives from homopropargyl acetals. Synthetic Communications.  ISSN 0039-7911.  44, s 2458- 2467 . doi: 10.1080/00397911.2014.902961
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders; Colas, Romain; Cheng, Chien-Yee C.; Dalli, Jesmond; Serhan, Charles N. & Hansen, Trond Vidar (2014). Total synthesis of the lipid mediator PD1n-3 DPA: Configurational assignments and anti-inflammatory and pro-resolving actions. Journal of natural products.  ISSN 0163-3864.  77(4), s 910- 916 . doi: 10.1021/np4009865
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders; Dalli, J. & Hansen, Trond Vidar (2014). Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator. Organic and biomolecular chemistry.  ISSN 1477-0520.  12(3), s 432- 437 . doi: 10.1039/c3ob41902a
  • Tungen, Jørn Eivind; Aursnes, Marius; Dalli, Jesmond; Arnardottir, Hildur; Serhan, Charles Nicholas & Hansen, Trond Vidar (2014). Total synthesis of the anti-inflammatory and pro-resolving lipid mediator MaR1<sub>n-3 DPA</sub>utilizing an sp<sup>3</sup>-sp<sup>3</sup> Negishi cross-coupling reaction. Chemistry - A European Journal.  ISSN 0947-6539.  20(45), s 14575- 14578 . doi: 10.1002/chem.201404721
  • Tungen, Jørn Eivind; Aursnes, Marius & Hansen, Trond Vidar (2014). Stereoselective total synthesis of ieodomycin C. Tetrahedron.  ISSN 0040-4020.  70(24), s 3793- 3797 . doi: 10.1016/j.tet.2014.04.020
  • Tungen, Jørn Eivind; Aursnes, Marius; Jesmond, Dalli; Hildur, Arnardottir; Serhan, Charles N & Hansen, Trond Vidar (2014). Total Synthesis of the Anti-inflammatory and Pro-resolving Lipid Mediator MaR1n-3 DPA Utilizing an sp3–sp3 Negishi Cross-Coupling Reaction. Chemistry - A European Journal.  ISSN 0947-6539.  20, s 14575- 14578 . doi: 10.1002/chem.201404721
  • Tungen, Jørn Eivind; Aursnes, Marius; Vik, Anders; Ramon, Sesquile; Colas, Romain A.; Dalli, Jesmond; Serhan, Charles N. & Hansen, Trond Vidar (2014). Synthesis and anti-inflammatory and pro-resolving activities of 22-OH-PD1, a monohydroxylated metabolite of protectin D1. Journal of natural products.  ISSN 0163-3864.  77(10), s 2241- 2247 . doi: 10.1021/np500498j
  • Tungen, Jørn Eivind; Nolsøe, Jens Mortansson J & Hansen, Trond Vidar (2012). Asymmetric Iodolactonization Utilizing Chiral Squaramides. Organic Letters.  ISSN 1523-7060.  14(23), s 5884- 5887 . doi: 10.1021/ol302798g
  • Sperger, Christian; Tungen, Jørn Eivind & Fiksdahl, Anne (2011). Gold(I)-Catalyzed Reactions of Propargyl Esters with Vinyl Derivatives. European Journal of Organic Chemistry.  ISSN 1434-193X.  (20-21), s 3719- 3722 . doi: 10.1002/ejoc.201100291

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  • Kristianslund, Renate; Aursnes, Marius; Tungen, Jørn Eivind; Görbitz, Carl Henrik & Hansen, Trond Vidar (2018). Enantioselective bromolactonization using chiral squaramides - Application in the total synthesis of (-)-sielboldianin A.
  • Kristianslund, Renate; Aursnes, Marius; Tungen, Jørn Eivind; Görbitz, Carl Henrik & Hansen, Trond Vidar (2017). Synthesis of (-)-sielboldianin A using a squaramide catalyzed enantioselective bromolactonization reaction.
  • Vik, Anders; Aursnes, Marius; Tungen, Jørn Eivind; Colas, Romain A.; Cheng, Chien-Yee C.; Dalli, Jesmond; Serhan, Charles Nicholas & Hansen, Trond Vidar (2017). Biosynthesis and the Anti-inflammatory and Pro-resolving Effects of the Novel Lipid Mediator Protectin D1n-3 DPA.
  • Aursnes, Marius; Tungen, Jørn Eivind & Hansen, Trond Vidar (2016). Enantioselective Organocatalyzed Bromolactonizations: Applications in Natural Product Synthesis. Show summary
  • Kristianslund, Renate; Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders & Hansen, Trond Vidar (2016). Organocatalytic enantioselective iodolactonization of allenoic acids.
  • Primdahl, Karoline Gangestad; Tungen, Jørn Eivind; Aursnes, Marius; Hansen, Trond Vidar & Vik, Anders (2016). Total Synthesis of Leukotriene B4.
  • Tungen, Jørn Eivind; Aursnes, Marius & Hansen, Trond Vidar (2016). A practical and highly enantioselective bromolactonization protocol utilizing squaramide-based catalysts.
  • Kristianslund, Renate; Tungen, Jørn Eivind; Nolsøe, Jens Mortansson Jelstrup; Stenstrøm, Yngve H. & Hansen, Trond Vidar (2015). Initial studies towards an enantioselective synthesis of 5-(S)-HEPE.
  • Sæther, Thomas; Moldes-Anaya, Angel; Tungen, Jørn Eivind; Vik, Anders; Paulsen, Steinar Martin; Sylte, Ingebrigt; Hansen, Trond Vidar & Nebb, Hilde Irene (2015). Anti-diabetic activity from marine lipids: new anti-diabetic drugs.
  • Tungen, Jørn Eivind; Aursnes, Marius & Hansen, Trond Vidar (2015). The first total synthesis of MaR1n-3 DPA.
  • Kritianslund, Renate; Tungen, Jørn Eivind; Nolsøe, Jens Mortansson J; Stenstrøm, Yngve & Hansen, Trond Vidar (2014). Initial studies towards an enantioselective synthesis of 5-HEPE.
  • Aursnes, Marius; Tungen, Jørn Eivind; Vik, Anders & Hansen, Trond Vidar (2013). Total synthesis of Protectin D1.
  • Tungen, Jørn Eivind; Nolsøe, Jens Mortansson J & Hansen, Trond Vidar (2013). Asymmetric Iodolactonization Utilizing Chiral Squaramides.
  • Tungen, Jørn Eivind; Nolsøe, Jens Mortansson J & Hansen, Trond Vidar (2013). Asymmetric Iodolactonization Utilizing Chiral Squaramides.
  • Tungen, Jørn Eivind; Nolsøe, Jens Mortansson J & Hansen, Trond Vidar (2012). Enantioselective Iodolactonization using Organocatalysis.
  • Landsem, Eva; Tungen, Jørn Eivind; Kristensen, Tor Erik; Unneberg, Erik; Benneche, Tore & Hansen, Finn Knut (2011). Isocyanate-Free Curing of Glycidyl Azide Polymer (GAP).
  • Tungen, Jørn Eivind & Fiksdahl, Anne (2011). Fremstilling av propargylestere og anvendelse i gullkatalyserte reaksjoner.
  • Tungen, Jørn Eivind; Sperger, Christian & Fiksdahl, Anne (2011). Gold(I)-catalysed reactions of Propargylesters with Vinyl-Derivatives.

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Published Oct. 17, 2016 10:54 AM