Ove Alexander Høgmoen Åstrand

Image of Ove Alexander Høgmoen Åstrand
Norwegian version of this page
Phone +47-22854478
Visiting address Sem Sælands vei 3 Farmasibygningen 0371 OSLO
Postal address Postboks 1068 Blindern 0316 OSLO

Academic Interests

 Organic chemistry, pharmacutical chemistry, organometallic chemistry, catalysis, chemical engineering, high energy chemistry, dissemination.


I teach introductary lab courses in

FRM1000 - Pharmaceutical Chemistry, Part I

FRM1010 - Pharmaceutical Chemistry, Part II

Higher education and employment history

  • 2009: Started graduate studies in pharmacutical chemistry under guidance of assistant professor Pål Rongved.
  • 2009: Sivilingeniør(diploma engineer) in organic chemistry from NTNU (Norwegian University of Science and Technology) in Trondheim. Diploma thesis written in the field of organometallic aziridination of olefins using ruthenium catalysts under the guidance of assistant professor Odd R. Gautun.
  • 2007/2008: 1 year study abroad at the University of California, Berkeley


Tags: Pharmaceutical chemistry, Medicinal chemistry, Chemistry, Pharmaceuticals, Life Science, Toxicology


  • Viktorsson, Elvar Örn; Gabrielsen, Mari; Kumarachandran, Nugalya; Sylte, Ingebrigt; Rongved, Pål; Åstrand, Ove Alexander Høgmoen & Kase, Eili Tranheim (2017). Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations. Steroids.  ISSN 0039-128X.  118, s 119- 127 . doi: 10.1016/j.steroids.2016.12.003
  • Viktorsson, Elvar Örn; Grøthe, Bendik Melling; Aesoy, Reidun; Sabir, Misbah; Snellingen, Simen; Åstrand, Ove Alexander Høgmoen; Prandina, Anthony; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars & Rongved, Pål (2017). Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. Bioorganic & Medicinal Chemistry.  ISSN 0968-0896.  25(7), s 2285- 2293 . doi: 10.1016/j.bmc.2017.02.058
  • Åstrand, Ove Alexander Høgmoen; Viktorsson, Elvar Örn; Kristensen, Aleksander Lim; Ekeberg, Dag; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon; Gabrielsen, Mari; Sylte, Ingebrigt; Rustan, Arild; Thoresen, G. Hege; Rongved, Pål & Kase, Eili Tranheim (2017). Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  165, s 323- 330 . doi: 10.1016/j.jsbmb.2016.07.010

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  • Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Bonge-Hansen, Tore; Doskeland, Stein Ove; Herfindal, Lars & Rongved, Pål (2016). Total synthesis and initial antileukemic evaluation of the phenazine 5,10-dioxide natural products iodinin and myxin.
  • Åstrand, Ove Alexander Høgmoen; Cokoja, Mirza; Pöthig, Alexander & Kühn, Fritz E. (2016). Zinc complexes in catalysis - Potential applications.
  • Åstrand, Ove Alexander Høgmoen; Schnaars, Christian; Kildahl-Andersen, Geir & Rongved, Pål (2016). Overcoming b-lactam resistance - A potential solution to antibiotic resistance.
  • Grøthe, Bendik Melling; Snellingen, Simen; Viktorsson, Elvar Örn; Prandina, Anthony; Åstrand, Ove Alexander Høgmoen; Bonge-Hansen, Tore & Rongved, Pål (2015). The first efficient synthesis and preliminary biological effect of the 1,6-dihydroxyphenazine-N5,N10-dioxide (Iodinin) and 1-hydroxy-6-methoxyphenazine-N5,N10-dioxide (Myxin).
  • Haseeb, Rasha Sabah; Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen & Rongved, Pål (2015). Synthetic efforts towards oxysterol-based LXR-modulators.
  • Prandina, Anthony; Frøvold, Espen; Åstrand, Ove Alexander Høgmoen & Rongved, Pål (2015). Synthetic efforts towards new agents against resistant bacteria.
  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan & Leiros, Hanna-Kirsti S. (2015). The fight against metallo-beta-lactamases and antibiotic resistance.

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Published June 3, 2014 11:29 AM - Last modified June 3, 2014 11:30 AM