Dag Erlend Olberg

Førsteamanuensis II - Seksjon for farmasøytisk kjemi
Bilde av Dag Erlend Olberg
English version of this page
Mobiltelefon +47 41517119
Brukernavn
Besøksadresse Sem Sælands vei 3 Farmasibygningen 0371 Oslo
Postadresse Postboks 1068 Blindern O316 Oslo

Faglige interesser

Radiokjemi (PET), legemiddelkjemi, CNS, peptidkjemi, biomolekyler og molekylær avbilding

Samarbeid

Nasjonalt

Kjetil Wessel Andressen, Avdeling for farmakologi, UiO, http://www.med.uio.no/klinmed/personer/vit/kjetilwa/

Finn Olav Levy, Avdeling for farmakologi, UiO, http://www.med.uio.no/klinmed/personer/vit/finnolav/

Frits Alan Thorsen, UiB, http://www.uib.no/personer/Frits.Thorsen

Thor Audun Saga, Norsk Medisinsk Syklotronsenter AS, http://www.petsenteret.no

Ira Ronit Haraldsen, OUS-Rikshospitalet, http://www.ous-research.no/home/iraharaldsen/Group%20members/8376

Gjermund Henriksen, Norsk Medisinsk Syklotronsenter AS, http://www.petsenteret.no

Internasjonalt

Guy Bormans, KU Leuven, Belgia, http://www.kuleuven.be/wieiswie/en/person/00009552

Martin G. Pomper, John Hopkins Medicine, Baltimore, MD, USA, http://www.hopkinsmedicine.org/pharmacology_molecular_sciences/faculty/bios/pomper.html

 

Emneord: Legemiddelkjemi, PET radiofarmaka, peptidsyntese, PET, Life sciences

Publikasjoner

  • Ahamed, Muneer; Vermeulen, Koen; Schnekenburger, Michael; Moltzau, Lise Roman; Levy, Finn Olav; Marton, Janos; Froeyen, Mathy; Olberg, Dag Erlend; Diederich, Marc & Bormans, Guy (2017). Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers. Letters in Drug Design & Discovery.  ISSN 1570-1808.  14(7), s 787- 797 . doi: 10.2174/1570180813666161101152943 Vis sammendrag
  • Lien, Vegard Torp; Klaveness, Jo & Olberg, Dag Erlend (2017). One-step synthesis of [18F]cabozantinib for use in positron emission tomography imaging of c-Met.. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803. . doi: 10.1002/jlcr.3564
  • Lien, Vegard Torp; Olberg, Dag Erlend; Klaveness, Jo & Görbitz, Carl Henrik (2017). Crystal structure of 6,7-dimeth­­oxy-1-(4-nitro­phen­yl)quinolin-4(1H)-one: a mol­ecular scaffold for potential tubulin polymerization inhibitors. Acta Crystallographica Section E: Crystallographic Communications.  ISSN 2056-9890.  73, s 441- 444 . doi: 10.1107/S2056989017002948
  • Olberg, Dag Erlend; Bauer, Nadine; Andressen, Kjetil Wessel; Hjornevik, Trine; Cumming, Paul; Levy, Finn Olav; Klaveness, Jo; Haraldsen, Ira Hebold & Sutcliffe, Julie L. (2016). Brain penetrant small molecule 18F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats. Nuclear Medicine and Biology.  ISSN 0969-8051.  43(8), s 478- 489 . doi: doi:10.1016/j.nucmedbio.2016.05.003
  • Olberg, Dag Erlend; Hausner, Sven H.; Bauer, Nadine; Klaveness, Jo; Indrevoll, Bård; Andressen, Kjetil Wessel; Dahl, Marie; Levy, Finn Olav; Sutcliffe, Julie L. & Haraldsen, Ira Hebold (2015). Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats. MedChemComm.  ISSN 2040-2503.  6, s 708- 714 . doi: 10.1039/c4md00486h
  • Cumming, Robin C.; Olberg, Dag Erlend & Sutcliffe, Julie L. (2014). Rapid 18F-radiolabeling of peptides from [18F] fluoride using a single microfluidics device. RSC Advances.  ISSN 2046-2069.  4(90), s 49529- 49534 . doi: 10.1039/c4ra10520f
  • Olberg, Dag Erlend; Andressen, Kjetil Wessel; Levy, Finn Olav; Klaveness, Jo; Haraldsen, Ira Hebold & Sutcliffe, Julie L. (2014). Synthesis and in vitro evaluation of small-molecule [18F] labeled gonadotropin-releasing hormone (GnRH) receptor antagonists as potential PET imaging agents for GnRH receptor expression. Bioorganic & Medicinal Chemistry Letters.  ISSN 0960-894X.  24(7), s 1846- 1850 . doi: 10.1016/j.bmcl.2014.02.002
  • Olberg, Dag Erlend; Hagen, Inger A.; Hagen, Anniken & Haraldsen, Ira Hebold (2012). Peptider for positronemisjonstomografi (PET). Norsk Farmaceutisk Tidsskrift.  ISSN 0029-1935.  120(1), s 20- 24
  • Wojniusz, Slawomir; Vögele, Claus; Ropstad, Erik; Evans, Neil; Robinson, Jane; Sütterlin, Stefan; Erhard, Hans W.; Solbakk, Anne-Kristin; Endestad, Tor; Olberg, Dag Erlend & Haraldsen, Ira Hebold (2011). Prepubertal gonadotropin-releasing hormone analog leads to exaggerated behavioral and emotional sex differences in sheep. Hormones and Behavior.  ISSN 0018-506X.  59, s 22- 27 . doi: 10.1016/j.yhbeh.2010.09.010 Vis sammendrag
  • Hjelstuen, ole kristian; Svadberg, Anders; Olberg, Dag Erlend & Rosser, Mark (2011). Standardization of fluorine-18 manufacturing processes: New scientific challenges for PET. European journal of pharmaceutics and biopharmaceutics.  ISSN 0939-6411.  78(3), s 307- 313 . doi: 10.1016/j.ejpb.2011.01.002
  • Olberg, Dag Erlend; Arukwe, Joseph M; Grace, David; Hjelstuen, ole kristian; Solbakken, Magne; Kindberg, Grete M. & Cuthbertson, Alan (2010). One Step Radiosynthesis of 6-[F-18]Fluoronicotinic Acid 2,3,5,6-Tetrafluorophenyl Ester ([F-18]F-Py-TFP): A New Prosthetic Group for Efficient Labeling of Biomolecules with Fluorine-18. Journal of Medicinal Chemistry.  ISSN 0022-2623.  53(4), s 1732- 1740 . doi: 10.1021/jm9015813
  • Olberg, Dag Erlend; Cuthbertson, Alan; Solbakken, Magne; Arukwe, Joseph M; Qu, Hong; Kristian, Alexandr; Bruheim, Skjalg & Hjelstuen, ole kristian (2010). Radiosynthesis and Biodistribution of a Prosthetic Group (F-18-FENMA) Conjugated to Cyclic RGD Peptides. Bioconjugate chemistry.  ISSN 1043-1802.  21(12), s 2297- 2304 . doi: 10.1021/bc1003229
  • Olberg, Dag Erlend & Hjelstuen, ole kristian (2010). Labeling Strategies of Peptides with F-18 for Positron Emission Tomography. Current Topics in Medicinal Chemistry.  ISSN 1568-0266.  10(16), s 1669- 1679
  • Høyem, Sverre; Bruheim, Skjalg; Mælandsmo, Gunhild M; Standal, Marius; Olberg, Dag Erlend; Brudeli, Bjarne; Åsberg, Anders; Klaveness, Jo & Rongved, Pål (2009). Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats. European Journal of Medicinal Chemistry.  ISSN 0223-5234.  44(10), s 3874- 3879 . doi: 10.1016/j.ejmech.2009.04.008
  • Høyem, Sverre; Bruheim, Skjalg; Mælandsmo, Gunhild; Standal, Marius; Olberg, Dag Erlend; Brudeli, Bjarne; Åsberg, Anders; Klaveness, Jo & Rongved, Pål (2009). Didanosine ester prodrugs: Synthesis, albumin binding properties and pharmacokinetic studies in rats. European Journal of Medicinal Chemistry.  ISSN 0223-5234.  44, s 3874- 3879
  • Olberg, Dag Erlend; Hjelstuen, ole kristian; Solbakken, Magne; Arukwe, Joseph M; Dyrstad, Knut & Cuthbertson, Alan (2009). Site-specific addition of an F-18-N-methylaminooxy-containing prosthetic group to a vinylsulfone modified peptide. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803.  52(13-14), s 571- 575 . doi: 10.1002/Jlcr.1686
  • Olberg, Dag Erlend; Hjelstuen, ole kristian; Solbakken, Magne; Arukwe, Joseph; Karlsen, Hege & Cuthbertson, Alan (2008). A novel prosthetic group for site-selective labeling of peptides for positron emission tomography. Bioconjugate chemistry.  ISSN 1043-1802.  19(6), s 1301- 1308 . doi: 10.1021/bc800007h

Se alle arbeider i Cristin

  • Lien, Vegard Torp; Klaveness, Jo & Olberg, Dag Erlend (2017). One-step synthesis of [18F]cabozantinib for use in positron emission tomography imaging of c-Met.
  • Cumming, Robin; Olberg, Dag Erlend & Sutcliffe, Julie (2013). Rapid high-yielding radiosynthesis of [F-18] F-Py-TFP using a microfluidic system. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803.  56, s S477- S477
  • Olberg, Dag Erlend; Haraldsen, Ira Hebold & Sutcliffe, J. (2013). Synthesis and evaluation of small molecular [F-18]labeled gonadotropin-releasing hormone (GnRH) receptor antagonist as potential PET imaging agents for GnRH receptor expression in CNS. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803.  56, s S333- S333
  • Olberg, Dag Erlend (2009). Novel (18F)Fluorinated prosthetic groups for the labelling of peptides for positron emission tomography (PET).
  • Olberg, Dag Erlend; Arukwe, J; Grace, D & Hjelstuen, ole kristian (2009). 2-TRIMETHYLAMMONIUM NICOTINIC ACID TFP-ESTER: A NOVEL PYRIDINE BASED SYSTEM FOR THE ONE-STEP LABELLING OF BIOMOLECULES WITH FLUORINE-18. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803.  52, s S160- S160
  • Olberg, Dag Erlend; Arukwe, J; Solbakken, M; Cuthbertson, A; Qu, H; Kristian, A & Hjelstuen, ole kristian (2009). RADIOSYNTHESIS AND BIODISTRIBUTION OF CYCLIC RGD PEPTIDES CONJUGATED WITH A NOVEL [18F] FLUORINATED N-METHYLAMINOOXY CONTAINING PROSTHETIC GROUP. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803.  52, s S32- S32
  • Olberg, Dag Erlend; Arukwe, Joseph M; Grace, D & Hjelstuen, ole kristian (2009). 2-Trimethylammonium nicotinic acid TFP-ester: A novel pyridine based system for the one-step labelling of biomolecules with fluorine-18.
  • Olberg, Dag Erlend; Hjelstuen, ole kristian; Solbakken, M; Arukwe, J; Dyrstad, K & Cuthbertson, A (2009). SITE-SPECIFIC ADDITION OF AN 18F-N-METHYLAMINOOXY CONTAINING PROSTHETIC GROUP TO A VINYLSULFONE MODIFIED PEPTIDE. Journal of labelled compounds & radiopharmaceuticals.  ISSN 0362-4803.  52, s S161- S161
  • Olberg, Dag Erlend; Hjelstuen, ole kristian; Solbakken, Magne; Arukwe, Joseph M; Dyrstad, Knut & Cuthbertson, Alan (2009). Site-specific addition of an 18F-N-Methylaminooxy containing prosthetic group to a vinylsulfone modified peptide.

Se alle arbeider i Cristin

Publisert 27. jan. 2015 10:17 - Sist endret 17. okt. 2016 11:52