Neurobiology - Fyhn
The brain has a remarkable ability to adapt to changing environments but the mechanisms underlying these processes in the brain of animals interacting with its environment remain elusive. In my research I want to identify the neural fingerprint that reflects learning of sensory experiences in cortical circuits from structural changes of synapses to changes in the population code of neural ensembles in behaving animals. To achieve this we use large scale extracellular recordings of populations of neurons and transcranial two photon laser scanning microscopy (2PLSM) to identify structural and functional changes of identified neurons. Understanding mechanisms underlying basic cortical plasticity and function will untangle how experience modifies cortical circuits to form long-lasting memories and have great impact on our understanding of normal brain function and help our understanding of what fails in the diseased brain.
Marianne Fyhn is director of Centre for Integrative Neuroplasticity (CINPLA), which is a strategic research initiative at the MN Faculty at UiO, aiming to reveal mechanisms underlying of the brain’s ability to change and learn from experiences. By integrating experimental methods with physics-based computational modeling and analysis we work to develop a creative and inspiring consortium which aims to deliver groundbreaking research and develop an interdisciplinary and high-quality educational program in Neuroscience at the faculty.