Frode Miltzow Skjeldal

The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes.
Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T.
Immunity. 2010 Oct 29;33(4):583-96. Epub 2010 Oct 7.

PMID:

    20933442
    [PubMed - indexed for MEDLINE]

Related citations

2.
Toll-like receptor 2 (P631H) mutant impairs membrane internalization and is a dominant negative allele.
Etokebe GE, Skjeldal F, Nilsen N, Rodionov D, Knezevic J, Bulat-Kardum L, Espevik T, Bakke O, Dembic Z.
Scand J Immunol. 2010 May;71(5):369-81.

PMID:

    20500688
    [PubMed - indexed for MEDLINE]

Related citations

3.
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36.
Nilsen NJ, Deininger S, Nonstad U, Skjeldal F, Husebye H, Rodionov D, von Aulock S, Hartung T, Lien E, Bakke O, Espevik T.
J Leukoc Biol. 2008 Jul;84(1):280-91. Epub 2008 May 5.

PMID:

    18458151
    [PubMed - indexed for MEDLINE]

Free Article
Related citations

4.
Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator.
Steffensen KR, Bouzga M, Skjeldal F, Kasi C, Karahasan A, Matre V, Bakke O, Guérin S, Eskild W.
BMC Mol Biol. 2007 Nov 16;8:106.

PMID:

    18021396
    [PubMed - indexed for MEDLINE]

Free PMC Article
Free full text

Related citations

• Skjeldal, Frode Miltzow; Haugen, Linda Hofstad; Nunes De C Mateus, Duarte; Frei, Dominik Michael; Rødseth, Anna Vik & Hu, Xian [Vis alle 7 forfattere av denne artikkelen] (2021). De novo formation of early endosomes during Rab5-to-Rab7a transition. Journal of Cell Science. ISSN 0021-9533. 134(8). doi: 10.1242/jcs.254185. Fulltekst i vitenarkiv Vis sammendrag

  Rab5 and Rab7a are the main determinants of early and late endosomes and are important regulators of endosomal progression. The transport from early endosomes to late endosome seems to be regulated through an endosomal maturation switch, where Rab5 is gradually exchanged by Rab7a on the same endosome. Here, we provide new insight into the mechanism of endosomal maturation, for which we have discovered a stepwise Rab5 detachment, sequentially regulated by Rab7a. The initial detachment of Rab5 is Rab7a independent and demonstrates a diffusion-like first-phase exchange between the cytosol and the endosomal membrane, and a second phase, in which Rab5 converges into specific domains that detach as a Rab5 indigenous endosome. Consequently, we show that early endosomal maturation regulated through the Rab5-to-Rab7a switch induces the formation of new fully functional Rab5-positive early endosomes. Progression through stepwise early endosomal maturation regulates the direction of transport and, concomitantly, the homeostasis of early endosomes.

• Kocere, Agnese; Resseguier, Julien; Wohlmann, Jens; Skjeldal, Frode Miltzow; Khan, Shanawaz & Speth, Martin [Vis alle 14 forfattere av denne artikkelen] (2020). Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine. ISSN 2352-3964. 58, s. 1–12. doi: 10.1016/j.ebiom.2020.102902. Fulltekst i vitenarkiv
• Mousavi, Seyed Ali; Skjeldal, Frode Miltzow; Fønhus, Marita Sporstøl; Haugen, Linda Hofstad; Eskild, Winnie & Berg, Trond [Vis alle 7 forfattere av denne artikkelen] (2019). Receptor-mediated endocytosis of VEGF-A in rat liver sinusoidal endothelial cells. BioMed Research International. ISSN 2314-6133. 2019, s. 1–12. doi: 10.1155/2019/5496197. Fulltekst i vitenarkiv
• Fauskanger, Marte; Haabeth, Ole Audun; Skjeldal, Frode Miltzow; Bogen, Bjarne & Tveita, Anders (2018). Tumor killing by CD4+ T cells is mediated via induction of inducible nitric oxide synthase-dependent macrophage cytotoxicity. Frontiers in Immunology. ISSN 1664-3224. 9:1684, s. 1–13. doi: 10.3389/fimmu.2018.01684. Fulltekst i vitenarkiv
• Fenaroli, Federico; Repnik, Urska; Xu, Yitian; Johann, Kerstin; Van Herck, Simon & Dey, Pradip [Vis alle 15 forfattere av denne artikkelen] (2018). Enhanced permeability and retention-like extravasation of nanoparticles from the vasculature into tuberculosis granulomas in zebrafish and mouse models. ACS Nano. ISSN 1936-0851. 12(8), s. 8646–8661. doi: 10.1021/acsnano.8b04433.
• Haugen, Linda Hofstad; Skjeldal, Frode Miltzow; Bergeland, Trygve & Bakke, Oddmund (2017). Endosomal binding kinetics of Eps15 and Hrs specifically regulate the degradation of RTKs. Scientific Reports. ISSN 2045-2322. 7:17962, s. 1–13. doi: 10.1038/s41598-017-17320-2. Fulltekst i vitenarkiv
• Kucera, Ana; Distefano, Marita Borg; Berg-Larsen, Axel; Skjeldal, Frode Miltzow; Repnik, Urska & Bakke, Oddmund [Vis alle 7 forfattere av denne artikkelen] (2016). Spatiotemporal Resolution of Rab9 and CI-MPR Dynamics in the Endocytic Pathway. Traffic: The moving front of cell biology. ISSN 1398-9219. 17(3), s. 211–229. doi: 10.1111/tra.12357.
• Hansson, Kenth-Arne; Døving, Kjell Bjarne & Skjeldal, Frode Miltzow (2015). Mixed input to olfactory glomeruli from two subsets of ciliated sensory neurons does not impede relay neuron specificity in the crucian carp. Journal of Experimental Biology. ISSN 0022-0949. 218(20), s. 3257–3263. doi: 10.1242/jeb.125476.
• Berven, Lise; Skjeldal, Frode Miltzow; Prydz, Kristian; Zubaidi, Layla Mohammad Khader; Ballance, Simon & Johansen, Harald Thidemann [Vis alle 7 forfattere av denne artikkelen] (2015). Particulate yeast β-glucan is internalized by RAW 264.7 macrophages and reduces the activity of the tumor-associated protease legumain. Bioactive Carbohydrates and Dietary Fibre. ISSN 2212-6198. 6(1), s. 15–23. doi: 10.1016/j.bcdf.2015.06.003.
• Bagheri Fam, Shahla; Skjeldal, Frode Miltzow; Griffiths, Gareth Wyn; Mælandsmo, Gunhild; Engebråten, Olav & Nyström, Bo [Vis alle 8 forfattere av denne artikkelen] (2015). pH-Responsive Nano Carriers for Doxorubicin Delivery. Pharmaceutical Research. ISSN 0724-8741. 32(4), s. 1249–1263. doi: 10.1007/s11095-014-1530-0.
• Fenaroli, Federico; Westmoreland, David; Benjaminsen, Jørgen; Kolstad, Terje R Selnes; Skjeldal, Frode Miltzow & Meijer, Annemarie H. [Vis alle 12 forfattere av denne artikkelen] (2014). Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment. ACS Nano. ISSN 1936-0851. 8(7), s. 7014–7026. doi: 10.1021/nn5019126.
• Jacobsen, Johanne Tracey; Gjerstad, Vibeke Sundvold; Skjeldal, Frode Miltzow; Andersen, Jan Terje; Abrahamsen, Greger & Bakke, Oddmund [Vis alle 8 forfattere av denne artikkelen] (2013). B-cell tolerance to the B-cell receptor variable regions. European Journal of Immunology. ISSN 0014-2980. 43(10), s. 2577–2587. doi: 10.1002/eji.201243203.
• Skjeldal, Frode Miltzow; Strunze, Sten; Bergeland, Trygve; Walseng, Even; Gregers, Tone Fredsvik & Bakke, Oddmund (2012). The fusion of early endosomes induces molecular-motor-driven tubule formation and fission. Journal of Cell Science. ISSN 0021-9533. 125(8), s. 1910–1919. doi: 10.1242/jcs.092569.
• Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow & Halaas, Øyvind [Vis alle 13 forfattere av denne artikkelen] (2010). The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity. ISSN 1074-7613. 33(4), s. 583–596. doi: 10.1016/j.immuni.2010.09.010.
• Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena & Bulat-Kardum, Ljiljana [Vis alle 9 forfattere av denne artikkelen] (2010). Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele. Scandinavian Journal of Immunology. ISSN 0300-9475. 71(5), s. 369–381. doi: 10.1111/j.1365-3083.2010.02379.x. Fulltekst i vitenarkiv
• Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald & Rodionov, D [Vis alle 12 forfattere av denne artikkelen] (2008). Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology. ISSN 0741-5400. 84, s. 280–291. doi: 10.1189/jlb.0907656.
• Steffensen, Knut Rune; Bouzga, Mariam; Skjeldal, Frode; Kåsi, Cecilie; Karahasan, Almira & Matre, Vilborg [Vis alle 9 forfattere av denne artikkelen] (2007). Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator. BMC Molecular Biology. ISSN 1471-2199. 8(1), s. 106–120.

Se alle arbeider i Cristin

• Samuelsen, Anne Berit C.; Berven, Lise; Rabani, Helai; Zubaidi, Layla & Skjeldal, Frode Miltzow (2015). Immunomodulating activities of fungal beta-glucans seem superior to those of cereal beta-glucans in vitro.
• Sundvold-Gjerstad, Vibeke; Kristiansen, Tone Fredsvik; Granum, Stine; Berge, Tone; Koster, Gerbrand & Skjeldal, Frode Miltzow [Vis alle 9 forfattere av denne artikkelen] (2011). T cell Specific Adapter Protein (TSAd) Relocates the Tec Family Protein Tyrosine Kinase Itk from the Plasma Membrane to the Perinuclear Area. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), s. 359–359.
• Doving, KB; Skjeldal, Frode Miltzow; Sandvig, Kirsten; Bakke, Oddmund; Heikkinen, I & Larsen, HK [Vis alle 7 forfattere av denne artikkelen] (2009). Fish Chemosenses; Olfaction, Taste, and Ligand-Specific Endocytosis. Chemical Senses. ISSN 0379-864X. 34(3), s. E13–E13.

Se alle arbeider i Cristin