Fahri Saatcioglu

Bilde av Fahri Saatcioglu
English version of this page
Telefon +47 22854569
Rom 3611
Brukernavn
Besøksadresse Blindernveien 31 0371 Oslo
Postadresse Postboks 1066 Blindern 0316 Oslo

Research Interests

The goal of the studies in our laboratory is to understand how androgens, male sex hormones, exert their effects on the normal physiology, as well as their role in disease states. Androgens bind to an intracellular receptor, called the androgen receptor (AR), that belongs to a superfamily of ligand-activated transcription factors, called nuclear receptors, which bring about changes in the phenotype of the cell through modulation of gene expression. To understand this process, we are using molecular, biochemical, cell biological and genetic approaches. Since androgens and AR have a significant role in prostate cancer, this work is also relevant for identification and validation of biomarkers or therapeutic targets for prostate cancer.

Teaching

MBV 3020 Genetics and developmental biology
MBV 3090 Research literature in cancer biology

Academic appointments

1/2013-Present       Professor, Dept. of Biosciences, University of Oslo
1/2002-12/2012      Professor, Dept. of Molecular Biosciences, University of Oslo
10/2000-Present     Visiting Scientist, Harvard School of Public Health, Boston, USA
02/2011-Present     Researcher (20%), Institute for Medical Informatics, Division of Surgery and Cancer Medicine, Oslo University Hospital, Oslo, Norway
11/2009-08/2010    Sabbatical, Harvard School of Public Health, Boston, USA
10/2000-11/2001    Sabbatical, Harvard School of Public Health, Boston, USA
7/1996-12/2001      Group Leader, Biotechnology Centre of Oslo, University of Oslo
10/1993-4/1996      Assistant Research Molecular Biologist, Department of Pharmacology, School of Medicine, University of California, San Diego, CA, USA
9/1990-9/1993        Post-doctoral fellow, Department of Pharmacology, School of Medicine, University of California, San Diego, CA, USA
3/1990-7/1990        Visiting scientist, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

Honors and distinctions

2009-2012      Special Cancer Program Award, Norwegian Research Council
2004-2007      Top Researcher Award, Norwegian Research Council
2004-2007       Special Cancer Program Award, Norwegian Research Council
2001-2003      Top Researcher Award, Norwegian Research Council
2000-2003      Special Cancer Program Award, Norwegian Research Council
1995-1996      ACS Institutional Fellowship, University of California, San Diego
1994-1995      Research Committee Award, University of California, San Diego
1993-1995       New Investigator Award, AIDS Related Disease Research Program, University of California
1992-1993       Post-doctoral fellowship, American Heart Association
1990-1992       Post-doctoral fellowship, Tobacco Related Disease Research Program, University of California
1987, 89, 90    Visiting Scientist Fellowship, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA (3-12 weeks at a time)
1987, 7-11       Visiting Researcher, Laboratory of Experimental Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD
1985                Salutatorian of the graduating class

Committees

Ad hoc grant review committees: Cancer Research UK; Prostate Cancer Charity UK; Australia Research Council; European Research Council. Member, Senior Editorial Board, American J. of Cancer Research, 2010-2013. Ad hoc reviewer for several international refereed journals, including Nature Reviews Cancer, Cancer Research, Clinical Cancer Research, Oncogene, J. of Pathology, Int. J. of Cancer, J. of Urology, Neoplasia, Tumor Biology, BMC Molecular Biology, Endocrine Related Cancer, Thrombosis and Haemostasis. Director, PhD Program, IMBV, University of Oslo, 2006-present. Advisor to eight PhD and 15 MSc students who have successfully completed their degrees, trained 6 postdoctoral fellows. Currently advisor for 3 PhD and 3 MSc students, and 2 postdoctoral fellows.

Current collaborations

University of Oslo
Oslo University Hospital
Cancer Registry of Norway
Umeå University, Sweden
Gothenborg University, Sweden
Lund University, Sweden
University of Porto, Portugal
Harvard University, USA
National Institutes of Health, USA
MD Andersen Cancer Center, USA
Vancouver Prostate Cancer, Canada

 

Emneord: Cell Signaling and Cancer

Publikasjoner

  • Korkmaz, Asli; Bernhardsen, Guro Pauck; Cirit, Burcu; Koprucu Suzer, Gayem; Kayan, Hale & Biçmen, Hülya [Vis alle 11 forfattere av denne artikkelen] (2024). Sudarshan Kriya Yoga Breathing and a Meditation Program for Burnout Among Physicians: A Randomized Clinical Trial. JAMA Network Open. ISSN 2574-3805. 7(1). doi: 10.1001/jamanetworkopen.2023.53978.
  • Sikkeland, Jørgen; Ng, Matthew; Nenseth, Hatice Zeynep; Ünal, Bilal; Qu, Su & Jin, Yang [Vis alle 8 forfattere av denne artikkelen] (2022). STAMP2 suppresses autophagy in prostate cancer cells by modulating the integrated stress response pathway. American Journal of Cancer Research. ISSN 2156-6976. 12(1), s. 327–336. Fulltekst i vitenarkiv
  • Saatcioglu, Fahri; Cirit, Burcu & Koprucu Suzer, Gayem (2022). The Promise of Well-Being Interventions to Mitigate Physician Burnout During the COVID-19 Pandemic and Beyond. JCO Oncology Practice (JCO OP). ISSN 2688-1527. 18(12), s. 808–814. doi: 10.1200/OP.22.00108. Fulltekst i vitenarkiv
  • Jin, Yixin; Lorvik, Kristina Berg; Jin, Yang; Beck, Carole; Sike, Adam & Persiconi, Irene [Vis alle 10 forfattere av denne artikkelen] (2022). Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer. Molecular Therapy Oncolytics. ISSN 2372-7705. 26, s. 189–206. doi: 10.1016/j.omto.2022.06.007.
  • Pällmann, Nora; Ke, Deng; Livgård, Marte; Tesikova, Martina; Jin, Yixin & Frengen, Nicolai Sebastian [Vis alle 18 forfattere av denne artikkelen] (2021). Stress-mediated reprogramming of prostate cancer one-carbon cycle drives disease progression. Cancer Research. ISSN 0008-5472. 81(15), s. 4066–4078. doi: 10.1158/0008-5472.CAN-20-3956. Fulltekst i vitenarkiv
  • Nenseth, Hatice Zeynep; Sahu, Aparna; Saatcioglu, Fahri & Osguthorpe, Steven (2021). A Nutraceutical Formula Is Effective in Raising the Circulating Vitamin and Mineral Levels in Healthy Subjects: A Randomized Trial. Frontiers in Nutrition. ISSN 2296-861X. 8. doi: 10.3389/fnut.2021.703394. Fulltekst i vitenarkiv
  • Pihlstrøm, Nicklas; Jin, Yang; Nenseth, Hatice Zeynep; Kuzu, Omer Faruk & Saatcioglu, Fahri (2021). Stamp2 expression mediated by cytokines attenuates their growth-limiting effects in prostate cancer cells. Cancers. ISSN 2072-6694. 13(7). doi: 10.3390/cancers13071579. Fulltekst i vitenarkiv
  • Guldvik, Ingrid Jenny; Zuber, Verena; Braadland, Peder Rustøen; Grytli, Helene Hartvedt; Ramberg, Håkon Andre & Lilleby, Wolfgang [Vis alle 18 forfattere av denne artikkelen] (2020). Identification and Validation of Leucine-rich alpha-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. European Urology Open Science. ISSN 2666-1691. 21, s. 51–61. doi: 10.1016/j.euros.2020.08.007. Fulltekst i vitenarkiv
  • Jin, Yang & Saatcioglu, Fahri (2020). Targeting the unfolded protein response in hormone-regulated cancers. Trends in Cancer. ISSN 2405-8033. 6(2), s. 160–171. doi: 10.1016/j.trecan.2019.12.001.
  • Pällmann, Nora; Livgård, Marte; Tesikova, Martina; Nenseth, Hatice Zeynep; Akkus, Erman & Sikkeland, Jørgen [Vis alle 20 forfattere av denne artikkelen] (2019). Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer. Oncogene. ISSN 0950-9232. 38, s. 6301–6318. doi: 10.1038/s41388-019-0879-2. Fulltekst i vitenarkiv
  • Sheng, Xia; Nenseth, Hatice Zeynep; Qu, Su; Kuzu, Ömer Faruk; Frahnow, Turid & Simon, Lukas [Vis alle 16 forfattere av denne artikkelen] (2019). IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling. Nature Communications. ISSN 2041-1723. 10:323, s. 1–12. doi: 10.1038/s41467-018-08152-3. Fulltekst i vitenarkiv
  • Sikkeland, Jørgen; Lindstad, Torstein; Nenseth, Hatice Zeynep; Dezitter, Xavier Gabriel M; Qu, Su & Mohamed Muhumed, Ridhwan [Vis alle 9 forfattere av denne artikkelen] (2019). Inflammation and ER stress differentially regulate STAMP2 expression and localization in adipocytes. Metabolism: Clinical and Experimental. ISSN 0026-0495. 93, s. 75–85. doi: 10.1016/j.metabol.2019.01.014. Fulltekst i vitenarkiv
  • Winje, Ivan; Sheng, Xia; Hansson, Kenth-Arne; Solbrå, Andreas Våvang; Tennøe, Simen & Saatcioglu, Fahri [Vis alle 8 forfattere av denne artikkelen] (2018). Cachexia does not induce loss of myonuclei or muscle fibres during xenografted prostate cancer in mice. Acta Physiologica. ISSN 1748-1708. s. 1–9. doi: 10.1111/apha.13204.
  • Jin, Yang; Nenseth, Hatice Zeynep & Saatcioglu, Fahri (2017). Role of PLZF as a tumor suppressor in prostate cancer. OncoTarget. ISSN 1949-2553. 8(41), s. 71317–71324. doi: 10.18632/oncotarget.19813.
  • Urbanucci, Alfonso; Barfeld, Stefan Jörg; Kytölä, Ville; Itkonen, Harri; Coleman, Ilsa M. & Vodák, Daniel [Vis alle 34 forfattere av denne artikkelen] (2017). Androgen receptor deregulation drives bromodomain-mediated chromatin alterations in prostate cancer. Cell reports. ISSN 2211-1247. 19(10), s. 2045–2059. doi: 10.1016/j.celrep.2017.05.049. Fulltekst i vitenarkiv
  • Lindstad, Torstein; Qu, Su; Sikkeland, Jørgen; Jin, Yang; Kristian, Alexandr & Mælandsmo, Gunhild [Vis alle 8 forfattere av denne artikkelen] (2016). STAMP2 is required for human adipose-derived stem cell differentiation and adiposite-facilitated prostrate cancer grown in vivo. OncoTarget. ISSN 1949-2553. 8(54), s. 91817–91827. doi: 10.18632/oncotarget.11131.
  • Tesikova, Martina; Dezitter, Xavier Gabriel M; Nenseth, Hatice Zeynep; Klokk, Tove Irene; Mueller, Florian & Hager, Gordon L. [Vis alle 7 forfattere av denne artikkelen] (2016). Divergent binding and transactivation by two related steroid receptors at the same response element. Journal of Biological Chemistry. ISSN 0021-9258. 291(22), s. 11899–11910. doi: 10.1074/jbc.M115.684480.
  • Sikkeland, Jørgen; Sheng, Xia; Jin, Yang & Saatcioglu, Fahri (2016). STAMPing at the crossroads of normal physiology and disease states. Molecular and Cellular Endocrinology. ISSN 0303-7207. 425, s. 26–36. doi: 10.1016/j.mce.2016.02.013.
  • Storm, Margrethe Larsdatter; Sheng, Xia; Arnoldussen, Yke Jildouw & Saatcioglu, Fahri (2016). Prostate cancer and the unfolded protein response. OncoTarget. ISSN 1949-2553. 7(33), s. 54051–54066. doi: 10.18632/oncotarget.9912. Fulltekst i vitenarkiv
  • Sheng, Xia; Arnoldussen, Yke Jildouw; Storm, Margrethe Larsdatter; Tesikova, Martina; Nenseth, Hatice Zeynep & Zhao, Sen [Vis alle 15 forfattere av denne artikkelen] (2015). Divergent androgen regulation of unfolded protein response pathways drives prostate cancer. EMBO Molecular Medicine. ISSN 1757-4676. 7(6), s. 788–801. doi: 10.15252/emmm.201404509. Fulltekst i vitenarkiv
  • Jin, Yang; Ling, Wang; Qu, Su; Sheng, Xia; Kristian, Alexandr & Mælandsmo, Gunhild [Vis alle 20 forfattere av denne artikkelen] (2015). STAMP2 increases oxidative stress and is critical for prostate cancer. EMBO Molecular Medicine. ISSN 1757-4676. 7(3), s. 315–331. doi: 10.15252/emmm.201404181. Fulltekst i vitenarkiv
  • Ertunc, Meric Erikci; Sikkeland, Jørgen; Fenaroli, Federico; Griffiths, Gareth Wyn; Daniels, Melissa C. & Cao, Haiming [Vis alle 8 forfattere av denne artikkelen] (2015). Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. Journal of Lipid Research. ISSN 0022-2275. 56(2), s. 423–434. doi: 10.1194/jlr.M055798.
  • Nenseth, Hatice Zeynep; Dezitter, Xavier; Tesikova, Martina; Mueller, Florian; Klokk, Tove Irene & Hager, Gordon L. [Vis alle 7 forfattere av denne artikkelen] (2014). Distinctly different dynamics and kinetics of two steroid receptors at the same response elements in living cells. PLOS ONE. ISSN 1932-6203. 9(8). doi: 10.1371/journal.pone.0105204. Fulltekst i vitenarkiv
  • Sikkeland, Jørgen; Jin, Yang & Saatcioglu, Fahri (2014). Methods to assess lipid accumulation in cancer cells. Methods in Enzymology. ISSN 0076-6879. 542, s. 407–423. doi: 10.1016/B978-0-12-416618-9.00021-2.
  • Saatcioglu, Fahri (2013). Regulation of gene expression by yoga, meditation and related practices: A review of recent studies. Asian Journal of Psychiatry. ISSN 1876-2018. 6(1), s. 74–77. doi: 10.1016/j.ajp.2012.10.002.
  • Jin, Yang; Qu, Su; Tesikova, Martina; Ling, Wang; Kristian, Alexandr & Mælandsmo, Gunhild [Vis alle 19 forfattere av denne artikkelen] (2013). Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 110(28), s. E2572–E2581. doi: 10.1073/pnas.1304318110.
  • Kaarbø, Mari; Storm, Margrethe; Qu, Su; Wæhre, Haakon; Risberg, Bjørn Åke & Danielsen, Håvard Emil [Vis alle 7 forfattere av denne artikkelen] (2013). TCTP is an androgen-regulated gene implicated in prostate cancer. PLOS ONE. ISSN 1932-6203. 8(7:e69398). doi: 10.1371/journal.pone.0069398. Fulltekst i vitenarkiv
  • Sikkeland, Jørgen & Saatcioglu, Fahri (2013). Differential Expression and Function of Stamp Family Proteins in Adipocyte Differentiation. PLOS ONE. ISSN 1932-6203. 8(7). doi: 10.1371/journal.pone.0068249. Fulltekst i vitenarkiv
  • Qu, Su; Olafsrud, Solveig Mjelstad; Meza-Zepeda, Leonardo Andrés & Saatcioglu, Fahri (2013). Rapid Gene Expression Changes in Peripheral Blood Lymphocytes upon Practice of a Comprehensive Yoga Program. PLOS ONE. ISSN 1932-6203. 8(4). doi: 10.1371/journal.pone.0061910.
  • ten Freyhaus, Henrik; Calay, Ediz S; Yalcin, Abdullah; Vallerie, Sara N; Yang, Ling & Calay, Zerrin Z [Vis alle 8 forfattere av denne artikkelen] (2012). Stamp2 Controls Macrophage Inflammation through Nicotinamide Adenine Dinucleotide Phosphate Homeostasis and Protects against Atherosclerosis. Cell Metabolism. ISSN 1550-4131. 16(1), s. 81–89. doi: 10.1016/j.cmet.2012.05.009.
  • Lazarevic, Bato; Hammarstrøm, Clara Louise; Yang, Jing; Ramberg, Håkon Andre; Diep, Lien My & Karlsen, Steinar [Vis alle 10 forfattere av denne artikkelen] (2012). The effects of short-term genistein intervention on prostate biomarker expression in patients with localised prostate cancer before radical prostatectomy. British Journal of Nutrition. ISSN 0007-1145. 108(12), s. 2138–2147. doi: 10.1017/S0007114512000384.
  • Lazarevic, Bato; Boezelijn, Gro; Diep, Lien My; Kvernrød, Kristin; Øgren, Hans Olov & Ramberg, Håkon Andre [Vis alle 16 forfattere av denne artikkelen] (2011). Efficacy and Safety of Short-Term Genistein Intervention in Patients with Localized Prostate Cancer Prior to Radical Prostatectomy: A Randomized, Placebo-Controlled, Double-Blind Phase 2 Clinical Trial. Nutrition and Cancer. ISSN 0163-5581. 63(6), s. 889–898. doi: 10.1080/01635581.2011.582221.
  • Varisli, Lokman; Gonen-Korkmaz, Ceren; Debelec-Butuner, Bilge; Erbaykent-Tepedelen, Burcu; Muhammed, Hamed Sayed & Bogurcu, Nuray [Vis alle 8 forfattere av denne artikkelen] (2011). Ubiquitously Expressed Hematological and Neurological Expressed 1 Downregulates Akt-Mediated GSK3 beta Signaling, and Its Knockdown Results in Deregulated G2/M Transition in Prostate Cells. DNA and Cell Biology. ISSN 1044-5498. 30(6), s. 419–429. doi: 10.1089/dna.2010.1128.
  • Lindstad, Torstein; Jin, Yang; Ling, Wang; Qu, Su & Saatcioglu, Fahri (2010). STAMPs at the Crossroads of Cancer and Nutrition. Nutrition and Cancer. ISSN 0163-5581. 62(7), s. 891–895. doi: 10.1080/01635581.2010.509836.
  • Ling, Wang; Jin, Yang; Arnoldussen, Yke Jildouw; Jonson, Ida; Qu, Su & Mælandsmo, Gunhild [Vis alle 11 forfattere av denne artikkelen] (2010). STAMP1 Is Both a Proliferative and an Antiapoptotic Factor in Prostate Cancer. Cancer Research. ISSN 0008-5472. 70(14), s. 5818–5828. doi: 10.1158/0008-5472.CAN-09-4697.
  • Kaarbø, Mari; Mikkelsen, Øyvind Løveseter; Malerød, Lene; Qu, Su; Lobert, Viola & Akgul, Gulcan [Vis alle 9 forfattere av denne artikkelen] (2010). PI3K-AKT-mTOR pathway is dominant over androgen receptor signaling in prostate cancer cells. Cellular Oncology. ISSN 1570-5870. 32(1-2), s. 11–27. doi: 10.3233/CLO-2009-0487.
  • Arnoldussen, Yke Jildouw & Saatcioglu, Fahri (2009). Dual specificity phosphatases in prostate cancer. Molecular and Cellular Endocrinology. ISSN 0303-7207. 309(1-2), s. 1–7. doi: 10.1016/j.mce.2009.05.019.
  • Fladeby, Cathrine; Nigam, Shailly; Gupta, Shailly N.; Barois, Nicolas; Lorenzo, Petri & Simpson, Jeremy C. [Vis alle 8 forfattere av denne artikkelen] (2008). Human PARM-1 is a novel mucin-like, androgen-regulated gene exhibiting proliferative effects in prostate cancer cells. International Journal of Cancer. ISSN 0020-7136. 122(6), s. 1229–1235. doi: 10.1002/ijc.23185.
  • Lazarevic, Bato; Karlsen, Steinar & Saatcioglu, Fahri (2008). Genistein differentially modulates androgen-responsive gene expression and activates JNK in LNCaP cells. Oncology Reports. ISSN 1021-335X. 19, s. 1231–1235.
  • Arnoldussen, Yke Jildouw; Lorenzo, Petra Isabel O.; Einarsen, Maria; Wæhre, Haakon; Risberg, Bjørn & Mælandsmo, Gunhild M [Vis alle 8 forfattere av denne artikkelen] (2008). The Mitogen-Activated Protein Kinase Phosphatase Vaccinia H1-Related Protein Inhibits Apoptosis in Prostate Cancer Cells and Is Overexpressed in Prostate Cancer. Cancer Research. ISSN 0008-5472. 68(22), s. 9255–9264. doi: 10.1158/0008-5472.CAN-08-1224.
  • Lorenzo, Petra Isabel O. & Saatcioglu, Fahri (2008). Inhibition of apoptosis in prostate cancer cells by androgens is mediated through downregulation of c-Jun N-terminal kinase activation. Neoplasia. ISSN 1522-8002. 10, s. 418–428. doi: 10.1593/neo.07985.
  • Kaarbø, Mari; Klokk, Tove Irene & Saatcioglu, Fahri (2007). Androgen signaling and its interaction with other signaling pathways in prostate cancer. Bioessays. ISSN 0265-9247. 29, s. 1227–1238. doi: 10.1002/bies.20676.
  • Klokk, Tove Irene; Kurys, Piotr Jerzy; Elbi, C; Nagaich, AK; Hendarwanto, A & Slagsvold, Thomas [Vis alle 9 forfattere av denne artikkelen] (2007). Ligand-specific dynamics of the androgen receptor at its response element in living cells. Molecular and Cellular Biology. ISSN 0270-7306. 27. doi: 10.1128/MCB.01297-06.
  • Klokk, Tove Irene; Kilander, Anette; Xi, Zhijun; Wæhre, Haakon; Risberg, Bjørn & Danielsen, Håvard Emil [Vis alle 7 forfattere av denne artikkelen] (2007). Kallikrein 4 is a proliferative factor that is overexpressed in prostate cancer. Cancer Research. ISSN 0008-5472. 67, s. 5221–5230. doi: 10.1158/0008-5472.CAN-06-4728.
  • Wellen, KE; Fucho, R; Gregor, MF; Furuhashi, M; Morgan, C & Lindstad, Torstein [Vis alle 10 forfattere av denne artikkelen] (2007). Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell. ISSN 0092-8674. 129. doi: 10.1016/j.cell.2007.02.049.
  • Davidson, B; Xi, Zhijun & Saatcioglu, Fahri (2007). Kallikrein 4 is expressed in malignant mesotheliorna-further evidence for the histogenetic link between mesothelial and epithelial cells. Diagnostic Cytopathology. ISSN 8755-1039. 35. doi: 10.1002/dc.20588.
  • Irer, SV; Alper, GE; Sezer, ED; Duman, E; Saatcioglu, Fahri & Yilmaz, C (2007). The effect of l-deprenyl on tissue mRNA expressions of NOS isoforms and NO levels in an experimental diabetes mellitus model. Journal of Neural Transmission. ISSN 0300-9564. 114. doi: 10.1007/s00702-007-0693-9.
  • kjellgren, a; bood, sa; Axelsson, K; Norlander, T & Saatcioglu, Fahri (2007). Wellness through a comprehensive Yogic breathing program - A controlled pilot trial. BMC Complementary and Alternative Medicine. ISSN 1472-6882. 7(1).
  • Aslan, G; Irer, B; Tuna, B; Yorukoglu, K; Saatcioglu, Fahri & Celebi, I (2006). analysis of NKX3.1 expression in prostate cancer tissues and correlation with clinicopathologic features. Pathology, Research and Practice. ISSN 0344-0338. 202(2), s. 93–98.
  • Frønsdal, Katrine & Saatcioglu, Fahri (2005). Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. The Prostate. ISSN 0270-4137. 62(3), s. 299–306.
  • Frønsdal, K. & Saatcioglu, Fahri (2005). Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. The Prostate. ISSN 0270-4137. 62(3), s. 299–306.
  • Lind, Gruo Elisabeth; Skotheim, Rolf Inge; Fraga, Mario F; Abeler, Vera Maria; Henrique, Rui & Saatcioglu, Fahri [Vis alle 9 forfattere av denne artikkelen] (2005). The loss of NKX3.1 expression in testicular - and prostate - cancers is not caused by promoter hypermethylation. Molecular Cancer. ISSN 1476-4598. 4(1). doi: 10.1186/1476-4598-4-8.
  • Davidson, Ben; Xi, Zhijun; Klokk, Tove Irene; Tropé, Claes Gøran; Dorum, Anne & Scheistroen, M [Vis alle 7 forfattere av denne artikkelen] (2005). Kallikrein 4 expression is up-regulated in epithelial ovarian carcinoma cells in effusions. American Journal of Clinical Pathology. ISSN 0002-9173. 123(3), s. 360–368.
  • Fronsdal, K & Saatcioglu, Fahri (2005). Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells. The Prostate. ISSN 0270-4137. 62.
  • Korkmaz, Ceren; Korkmaz, Kemal; Kurys, Piotr Jerzy; Elbi, Cem; Ling, Wang & Klokk, Tove Irene [Vis alle 10 forfattere av denne artikkelen] (2005). Molecular cloning and characterization of STAMP2, an andogen-regulated six transmembrane protein that is overexpressed in prostate cancer. Oncogene. ISSN 0950-9232. 24(31), s. 4934–45.
  • Xi, Zhijun; Kærn, Janne; Davidson, Ben; Klokk, Tove Irene; Risberg, Bjørn & Tropé, Claes Gøran [Vis alle 7 forfattere av denne artikkelen] (2004). Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer. Gynecologic Oncology. ISSN 0090-8258. 94, s. 80–85. doi: 10.1016/j.ygyno.2004.03.044.
  • Xi, Zhijun; Klokk, Tove Irene; Korkmaz, Kemal; Kurys, Piotr Jerzy; Elbi, C & Risberg, Bjørn [Vis alle 9 forfattere av denne artikkelen] (2004). Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer. Cancer Research. ISSN 0008-5472. 64(7), s. 2365–2370.
  • Lorenzo, Petra Isabel O. & Saatcioglu, Fahri (2004). Potentiation of androgen receptor transcriptional activity by inhibition of histone deacetylation--rescue of transcriptionally compromised mutants. Journal of Endocrinology. ISSN 0022-0795. 182.
  • Korkmaz, Ceren; Korkmaz, Kemal; Manola, Judith; Xi, Zhijun; Risberg, Bjørn & Danielsen, Håvard Emil [Vis alle 9 forfattere av denne artikkelen] (2004). Analysis of androgen regulated homeobox gene NKX3.1 during prostate carcinogenesis. Journal of Urology. ISSN 0022-5347. 172, s. 1134–1139.
  • Skotheim, Rolf Inge; Korkmaz, Kemal; Klokk, Tove Irene; Abeler, Vera M; Korlmaz, CG & Nesland, Jahn M [Vis alle 9 forfattere av denne artikkelen] (2003). NKX3.1 expression is lost in testicular germ cell tumors. American Journal of Pathology. ISSN 0002-9440. 163(6), s. 2149–2154.
  • Bratland, Åse; Ragnhildstveit, Erlend; Bjørnland, Kristin; Andersen, Kristin; Mælandsmo, Gunhild Mari & Fodstad, Øystein [Vis alle 8 forfattere av denne artikkelen] (2003). The metalloproteinase inhibitor TIMP-2 is down-regulated by androgens in LNCaP prostate carcinoma cells. Clinical and Experimental Metastasis. ISSN 0262-0898. 20(6), s. 541–547.
  • Thuestad, Gunnar; Berghagen, Hege; Ragnhildstveit, Erlend; Krogsrud, Kristin; Apriletti, James & Saatcioglu, Fahri (2002). Corepressor SMRT Functions as a Coactivator for Thyroid Hormone Receptor T3Ralpha from a Negative Hormone Response Element. Journal of Biological Chemistry. ISSN 0021-9258. 277(51), s. 49517–49522.
  • Berghagen, H.; Krogsrud, K.; Ragnhildstveit, Erlend; Thuestad, Gunnar; Aprilletti, J. & Saatcioglu, Fahri (2002). Corepressor SMRT Functions as a Coactivator for Thyroid Hormone Receptor T3Ralpha from a Negative Hormone Response Element. Journal of Biological Chemistry. ISSN 0021-9258. 277(51), s. 49517–49522.
  • Korkmaz, Kemal; Elbi, C.; Korkmaz, Ceren; Loda, M.; Hager, G. & Saatcioglu, Fahri (2002). Molecular cloning and characterization of STAMP1, a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer. Journal of Biological Chemistry. ISSN 0021-9258. 277(39), s. 36689–36696.
  • Yamamoto, Takeshi; Saatcioglu, Fahri & Matsuda, T. (2002). Cross-talk between bone morphogenic proteins and estrogen receptor signaling. Endocrinology. ISSN 0013-7227. 143(7), s. 2635–2642.
  • Engedal, Nikolai; Korkmaz, Ceren & Saatcioglu, Fahri (2002). C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP. Oncogene. ISSN 0950-9232. 21(7), s. 1017–1027.
  • Saatcioglu, Fahri & Engedal, Nikolai (2001). Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features. The Prostate. ISSN 0270-4137. 46, s. 289–297.
  • Thompson, J.H.; Saatcioglu, Fahri; Jänne, O. A. & Palvimo, J. J. (2001). Discrupted Amino-and Carboxyl-terminal Interactions of the Androgen Receptor Are Linked to Androgen Insensitivity. Molecular Endocrinology. ISSN 0888-8809. 15, s. 923–935.
  • Matsuda, T.; Junicho, A.; Yamamoto, Takeshi; Kishi, H.; Korkmaz, Kemal & Saatcioglu, Fahri [Vis alle 8 forfattere av denne artikkelen] (2001). Coss-talk between IL-6 and androgen receptor signaling in prostate carcinoma cells. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. 283, s. 179–187.
  • Korkmaz, Kemal; Korkmaz, Ceren; Ragnhildstveit, Erlend; Pretlow, T. G. & Saatcioglu, Fahri (2001). KLK4/KLK1/Prostase has a distinctly different gene structure compared with other members of the kallikrein family Alternative cDNA forms and regulation by multiple hormones. DNA and Cell Biology. ISSN 1044-5498. 20, s. 435–445.
  • Slagsvold, Tore; Kraus, I.; Frønsdal, K. & Saatcioglu, Fahri (2001). A novel transcriptional function of the androgen receptor through triggering of coactivators. Journal of Biological Chemistry. ISSN 0021-9258. 276, s. 31030–31036.
  • Matsuda, T.; Yamamoto, Takeshi; Muraguchi, A. & Saatcioglu, Fahri (2001). Cross-talk between transforming growth factor-b and estrogen receptor signaling through Smad3. Journal of Biological Chemistry. ISSN 0021-9258. 276, s. 42908–42914.
  • Engedal, Nikolai; Korkmaz, Ceren & Saatcioglu, Fahri (2001). c-Jun N-terminal kinase is required for the induction of apoptosis in prostate cancer cells. Oncogene. ISSN 0950-9232. In Press.
  • Saatcioglu, Fahri; Engedal, Nikolai & Frønsdal, K. (2000). Efficient methods for DNA-mediated gene transfer into prostate cancer cell line LNCaP. The Prostate. ISSN 0270-4137. s. 111–117.
  • Saatcioglu, Fahri; Apriletti, J.; Thuestad, Gunnar & Kraus, I. (2000). The N-terminal domain of thyroid hormone receptor alpha is required for all of its biological activities. DNA and Cell Biology. ISSN 1044-5498. s. 389–399.
  • Saatcioglu, Fahri; Korkmaz, Kemal; Korkmaz, Ceren; Ragnhildstveit, Erlend & Pretlow, T. G. (2000). An Efficient procedure to clone hormone responsive genes from a specific tissue. DNA and Cell Biology. ISSN 1044-5498. s. 499–506.
  • Saatcioglu, Fahri; Slagsvold, Tore; Bentzen, Tore; Kraus, I. & Palvimo, J. J. (2000). Mutational analysis of the androgen receptor AF-2 core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors. Molecular Endocrinology. ISSN 0888-8809. s. 1603–1617.
  • Saatcioglu, Fahri; Korkmaz, Kemal; Korkmaz, Ceren; Ragnhildstveit, Erlend & Pretlow, T. G. (2000). Full-length cDNA sequence and genomic organization of human NKX3.1-Alternative forms and regulation by both androgens and estrogens. Gene. ISSN 0378-1119. s. 25–36.
  • Saatcioglu, Fahri; Junicho, A.; Matsuda, T.; Yamamoto, Takeshi; Kishi, H. & Korkmaz, Kemal [Vis alle 8 forfattere av denne artikkelen] (2000). Protein inhibitor of activated STAT3 regulates androgen receptor signaling in prostate carcinoma cells. Biochemical and Biophysical Research Communications - BBRC. ISSN 0006-291X. s. 9–13.
  • Yamamoto, Takeshi; Matsuda, T.; Junicho, A.; Kishi, H.; Saatcioglu, Fahri & Muraguchi, A. (2000). Cross-talk between signal transducer and activator of transcription 3 and estrogen receptor signaling. FEBS Letters. ISSN 0014-5793. s. 143–148.

Se alle arbeider i Cristin

  • Storm, Margrethe; Kaarbo, Mari; Qu, Su; Wæhre, Haakon; Risberg, Bjørn Åke & Danielsen, Håkon [Vis alle 7 forfattere av denne artikkelen] (2013). TCTP is Androgen-Regulated and Over-Expressed in Prostate Cancer. The FASEB Journal. ISSN 0892-6638. 27.
  • Tesikova, Martina; Dezitter, Xavier; Klokk, Tove Irene; Kirli, Zeynep; Hager, Gordon L. & Saatcioglu, Fahri (2011). Differential effects of histone deacetylase inhibitors on transcription factor dynamics and activity at the same response element. The FASEB Journal. ISSN 0892-6638. 25.
  • Lorenzo, Petra Isabel O.; Arnoldussen, Yke Jildouw & Saatcioglu, Fahri (2007). Molecular mechanisms of apoptosis in prostate cancer. Critical reviews in oncogenesis. ISSN 0893-9675. 13(1), s. 1–38.
  • Lindstad, Torstein & Saatcioglu, Fahri (2007). Feit og frisk? [Internett]. Forskning.no.
  • Lindstad, Torstein & Saatcioglu, Fahri (2007). Mus mot fedme. [Avis]. Dagbladet.
  • Davidson, Ben; Xi, Zhijun; Klokk, Tove Irene; Trope, Claes Gøran; Dørum, Anne & Scheistrøen, Marit [Vis alle 7 forfattere av denne artikkelen] (2004). Expression of kallikrein 4 in epithelial ovarian carcinoma at different sites - evidence of divergent clinical role for tumor and stromal cells. Abstr. nr 128, s 451. Gynecologic Oncology. ISSN 0090-8258. 92(1), s. 393–511.
  • Lazarevic, B; Karlsen, Steinar; Kucuk, O & Saatcioglu, Fahri (2004). Genistein differentially regulates prostate-enriched protein expression in prostate cancer. Journal of Nutrition. ISSN 0022-3166. 134, s. 1258S–1258S.
  • Saatcioglu, Fahri (2004). Kallikrein 4 is a secreted protein - Response. Cancer Research. ISSN 0008-5472. 64, s. 8482–8483.
  • Xi, Zhijun; Klokk, Tove Irene & Saatcioglu, Fahri (2004). Expression of kallikrein 4 in epithelial ovarian carcinoma at different sites - evidence of divergent clinical role for tumor and stromal cells. Abstr 128.
  • Lazarevic, B; Karlsen, Steinar; Kucuk, O & Saatcioglu, Fahri (2003). Genistein differentially regulates prostate enriched protein expression in prostate cancer cells.
  • Thuestad, Gunnar; Kraus, Irene; Apriletti, James & Saatcioglu, Fahri (2000). DNA and Cell Biology The N-Terminal Domain of Thyroid Hormone Receptor-α Is Required for Its Biological Activities. ?. 19(7), s. 389–399.

Se alle arbeider i Cristin

Publisert 4. nov. 2010 14:47 - Sist endret 14. feb. 2024 13:54

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