Rolf I. Skotheim

Professor II

Main position as Group Leader at Oslo University Hospital.

Tags: Bioinformatics, Cancer biology, Genomics, Life sciences

Publications

  • Sveen, Anita; Johannessen, Bjarne; Klokkerud, Solveig M.K.; Kraggerud, Sigrid M.; Meza, Leonardo Zepeda & Bjørnslett, Merete Pauline [Show all 13 contributors for this article] (2024). Evolutionary mode and timing of dissemination of high-grade serous carcinomas. JCI Insight. ISSN 2379-3708. 9(3). doi: 10.1172/jci.insight.170423.
  • Skotheim, Rolf I.; Bogaard, Mari; Carm, Kristina Totland; Axcrona, Ulrika & Axcrona, Karol (2024). Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature. Biochimica et Biophysica Acta. CR. Reviews on Cancer. ISSN 0304-419X. 1879(2). doi: 10.1016/j.bbcan.2024.189080.
  • Bogaard, Mari; Skotheim, Rolf I.; Maltau, Aase Margrethe Victoria; Kidd, Susanne Gundersen; Lothe, Ragnhild Adelheid & Axcrona, Karol [Show all 7 contributors for this article] (2023). "High proliferative cribriform prostate cancer" defines a patient subgroup with an inferior prognosis. Histopathology. ISSN 0309-0167. 83(6), p. 853–869. doi: 10.1111/his.15012. Full text in Research Archive
  • Strømme, Jonas Meier; Johannessen, Bjarne & Skotheim, Rolf I. (2023). Deviating Alternative Splicing as a Molecular Subtype of Microsatellite Stable Colorectal Cancer. JCO Clinical Cancer Informatics. ISSN 2473-4276. 7. doi: 10.1200/CCI.22.00159. Full text in Research Archive
  • Grasso, Chiara; Popovic, Maja; Isaevska, Elena; Lazzarato, Fulvio; Fiano, Valentina & Zugna, Daniela [Show all 47 contributors for this article] (2022). Association Study between Polymorphisms in DNA Methylation-Related Genes and Testicular Germ Cell Tumor Risk. Cancer Epidemiology, Biomarkers and Prevention. ISSN 1055-9965. 31(9), p. 1769–1779. doi: 10.1158/1055-9965.EPI-22-0123.
  • Carm, Kristina Totland; Johannessen, Bjarne; Bogaard, Mari; Bakken, Anne Cathrine; Maltau, Aase Margrethe Victoria & Hoff, Andreas Midbøe [Show all 10 contributors for this article] (2022). Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer. International Journal of Cancer. ISSN 0020-7136. 152(5), p. 945–951. doi: 10.1002/ijc.34226. Full text in Research Archive
  • Kidd, Susanne Gundersen; Bogaard, Mari; Carm, Kristina Totland; Bakken, Anne Cathrine; Maltau, Aase Margrethe Victoria & Løvf, Marthe [Show all 10 contributors for this article] (2022). In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis. Molecular Oncology. ISSN 1574-7891. 16(15), p. 2810–2822. doi: 10.1002/1878-0261.13225. Full text in Research Archive
  • Fontugne, Jacqueline; Cai, Peter Y.; Alnajar, Hussein; Bhinder, Bhavneet; Park, Kyung & Ye, Huihui [Show all 26 contributors for this article] (2022). Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci. JCI Insight. ISSN 2379-3708. 7(4). doi: 10.1172/jci.insight.155309.
  • Strømme, Jonas Meier; Johannessen, Bjarne; Kidd, Susanne Gundersen; Bogaard, Mari; Carm, Kristina Totland & Zhang, Xiaokang [Show all 12 contributors for this article] (2022). Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity. Cancer Gene Therapy. ISSN 0929-1903. 29(8-9), p. 1276–1284. doi: 10.1038/s41417-022-00444-7.
  • Wolowczyk, Camilla; Neckmann, Ulrike; Aure, Miriam Ragle; Hall, Martina; Johannessen, Bjarne & Zhao, Sen [Show all 14 contributors for this article] (2022). NRF2 drives an oxidative stress response predictive of breast cancer. Free Radical Biology & Medicine. ISSN 0891-5849. 184, p. 170–184. doi: 10.1016/j.freeradbiomed.2022.03.029. Full text in Research Archive
  • Pluta, John; Pyle, Louise C.; Nead, Kevin T.; Wilf, Rona; Li, Mingyao & Mitra, Nandita [Show all 57 contributors for this article] (2021). Identification of 22 susceptibility loci associated with testicular germ cell tumors. Nature Communications. ISSN 2041-1723. 12(1), p. 1–13. doi: 10.1038/s41467-021-24334-y.
  • Sveen, Anita; Johannessen, Bjarne; Eilertsen, Ina Andrassy; Røsok, Bård Ingvald; Gulla, Marie & Eide, Peter Andreas Wold [Show all 14 contributors for this article] (2021). The expressed mutational landscape of microsatellite stable colorectal cancers. Genome Medicine. ISSN 1756-994X. 13. doi: 10.1186/s13073-021-00955-2. Full text in Research Archive
  • Tryggestad, Anne Merete Aaland; Axcrona, Karol; Axcrona, Ulrika; Bigalke, Iris; Brennhovd, Bjørn & Inderberg, Else Marit [Show all 19 contributors for this article] (2021). Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy. The Prostate. ISSN 0270-4137. 82(2), p. 245–253. doi: 10.1002/pros.24267.
  • Kidd, Susanne Gundersen; Carm, Kristina Totland; Bogaard, Mari; Olsen, Linn Guro; Bakken, Anne Cathrine & Løvf, Marthe [Show all 10 contributors for this article] (2021). High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity. Neoplasia. ISSN 1522-8002. 23(6), p. 634–641. doi: 10.1016/j.neo.2021.05.012. Full text in Research Archive
  • Hoff, Andreas Midbøe; Kraggerud, Sigrid M.; Alagaratnam, Sharmini; Berg, Kaja Christine Graue; Johannessen, Bjarne & Høland, Maren [Show all 11 contributors for this article] (2020). Frequent copy number gains of SLC2A3 and ETV1 in testicular embryonal carcinomas. Endocrine-Related Cancer. ISSN 1351-0088. 27(9), p. 457–468. doi: 10.1530/ERC-20-0064. Full text in Research Archive
  • Zhao, Sen; Hoff, Andreas Midbøe & Skotheim, Rolf I. (2020). ScaR - A tool for sensitive detection of known fusion transcripts: Establishing prevalence of fusions in testicular germ cell tumors. NAR Genomics and Bioinformatics. ISSN 2631-9268. 2(1). doi: 10.1093/nargab/lqz025.
  • Neckmann, Ulrike; Wolowczyk, Camilla; Hall, Martina; Almaas, Eivind; Ren, Jiang & Zhao, Sen [Show all 11 contributors for this article] (2019). GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients. Cell Communication and Signaling. ISSN 1478-811X. 17. doi: 10.1186/s12964-019-0467-7. Full text in Research Archive
  • Carm, Kristina Totland; Hoff, Andreas Midbøe; Bakken, Anne Cathrine; Axcrona, Ulrika; Axcrona, Karol & Lothe, Ragnhild A [Show all 8 contributors for this article] (2019). Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer. Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-49964-7. Full text in Research Archive
  • Smeby, Jørgen; Sveen, Anita; Eilertsen, Ina Andrassy; Danielsen, Stine Aske; Hoff, Andreas Midbøe & Eide, Peter Andreas Wold [Show all 12 contributors for this article] (2019). Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer. Oncogenesis. ISSN 2157-9024. 8:35(6), p. 1–8. doi: 10.1038/s41389-019-0141-3. Full text in Research Archive
  • Eilertsen, Ina Andrassy; Sveen, Anita; Strømme, Jonas Meier; Skotheim, Rolf I.; Nesbakken, Arild & Lothe, Ragnhild A (2018). Alternative splicing expands the prognostic impact of KRAS in microsatellite stable primary colorectal cancer . International Journal of Cancer. ISSN 0020-7136. 144(4), p. 841–847. doi: 10.1002/ijc.31809. Full text in Research Archive
  • Celestino, Ricardo; Nome, Torfinn; Pestana, Ana; Hoff, Andreas Midbøe; Gonçalves, A. Pedro & Pereira, Luísa [Show all 12 contributors for this article] (2018). CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension. BMC Cancer. ISSN 1471-2407. 18:68, p. 1–16. doi: 10.1186/s12885-017-3948-3. Full text in Research Archive
  • Løvf, Marthe; Zhao, Sen; Axcrona, Ulrika; Johannessen, Bjarne; Bakken, Anne Cathrine & Carm, Kristina Totland [Show all 13 contributors for this article] (2018). Multifocal primary prostate cancer exhibits high degree of genomic heterogeneity. European Urology. ISSN 0302-2838. p. 1–8. doi: 10.1016/j.eururo.2018.08.009.
  • Smebye, Marianne Lislerud; Agostini, Antonio; Johannessen, Bjarne; Thorsen, Jim; Davidson, Ben & Tropé, Claes Gøran [Show all 9 contributors for this article] (2017). Involvement of DPP9 in gene fusions in serous ovarian carcinoma. BMC Cancer. ISSN 1471-2407. 17(1). doi: 10.1186/s12885-017-3625-6.
  • Zhao, Sen; Løvf, Marthe; Carm, Kristina Totland; Bakken, Anne Cathrine; Hoff, Andreas Midbøe & Skotheim, Rolf I. (2017). Novel transcription-induced fusion RNAs in prostate cancer. OncoTarget. ISSN 1949-2553. 8(30), p. 49133–49143. doi: 10.18632/oncotarget.17099.
  • Berg, Kaja Christine Graue; Eide, Peter Andreas Wold; Eilertsen, Ina Andrassy; Johannessen, Bjarne; Bruun, Jarle & Danielsen, Stine Aske [Show all 14 contributors for this article] (2017). Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies. Molecular Cancer. ISSN 1476-4598. 16:116, p. 1–16. doi: 10.1186/s12943-017-0691-y.
  • Sveen, Anita; Johannessen, Bjarne; Tengs, Torstein; Danielsen, Stine Aske; Eilertsen, Ina Andrassy & Lind, Guro Elisabeth [Show all 16 contributors for this article] (2017). Multilevel genomics of colorectal cancers with microsatellite instability – clinical impact of JAK1 mutations and consensus molecular subtype 1. Genome Medicine. ISSN 1756-994X. 9(1). doi: 10.1186/s13073-017-0434-0.
  • Lågstad, Stian; Zhao, Sen; Hoff, Andreas Midbøe; Johannessen, Bjarne; Lingjærde, Ole Christian & Skotheim, Rolf I. (2017). Chimeraviz: A tool for visualizing chimeric RNA. Bioinformatics. ISSN 1367-4803. 33(18), p. 2954–2956. doi: 10.1093/bioinformatics/btx329.
  • Smebye, Marianne Lislerud; Haugom, Lisbeth; Davidson, Ben; Tropé, Claes Gøran; Heim, Sverre & Skotheim, Rolf I. [Show all 7 contributors for this article] (2017). Bilateral ovarian carcinomas differ in the expression of metastasis-related genes. Oncology Letters. ISSN 1792-1074. 13(1), p. 184–190. doi: 10.3892/ol.2016.5384.
  • Moen, Line Victoria; Ramberg, Håkon Andre; Zhao, Sen; Grytli, Helene Hartvedt; Sveen, Anita & Berge, Viktor [Show all 9 contributors for this article] (2017). Observed correlation between the expression levels of catalytic subunit, C?2, of cyclic adenosine monophosphate-dependent protein kinase and prostate cancer aggressiveness. Urologic Oncology. ISSN 1078-1439. 35(3), p. 111.e1–111.e8. doi: 10.1016/j.urolonc.2016.10.002.
  • Ramberg, Håkon Andre; Grytli, Helene Hartvedt; Nygård, Ståle; Wang, Wanzhong; Øgren, Hans Olav & Zhao, Sen [Show all 14 contributors for this article] (2016). PBX3 is a putative biomarker of aggressive prostate cancer. International Journal of Cancer. ISSN 0020-7136. 139(8), p. 1810–1820. doi: 10.1002/ijc.30220.
  • Sveen, Anita; Kilpinen, Sami; Ruusulehto, Anja; Lothe, Ragnhild A & Skotheim, Rolf Inge (2016). Aberrant RNA splicing in cancer; Expression changes and driver mutations of splicing factor genes. Oncogene. ISSN 0950-9232. 35(19), p. 2413–2427. doi: 10.1038/onc.2015.318.
  • Lorenz, Susanne; Barøy, Tale; Sun, Jinchang; Nome, Torfinn; Vodak, Daniel & Bryne, Jan Christian [Show all 21 contributors for this article] (2016). Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations. OncoTarget. ISSN 1949-2553. 7(5), p. 5273–5288. doi: 10.18632/oncotarget.6567.
  • Hoff, Andreas Midbøe; Alagaratnam, Sharmini; Zhao, Sen; Bruun, Jarle; Andrews, PW & Lothe, Ragnhild A [Show all 7 contributors for this article] (2016). Identification of novel fusion genes in testicular germ cell tumors. Cancer Research. ISSN 0008-5472. 76(1), p. 108–116. doi: 10.1158/0008-5472.CAN-15-1790.
  • Cekaite, Lina; Eide, Peter Andreas Wold; Lind, Guro Elisabeth; Skotheim, Rolf I. & Lothe, Ragnhild A (2015). MicroRNAs as growth regulators, their function and biomarker status in colorectal cancer. OncoTarget. ISSN 1949-2553. 7(6), p. 6476–6505. doi: 10.18632/oncotarget.6390.
  • Munkley, Jennifer; Oltean, Sebastian; Vodak, Daniel; Wilson, Brian T.; Livermore, Karen E. & Zhou, Yan [Show all 20 contributors for this article] (2015). The androgen receptor controls expression of the cancerassociated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer. OncoTarget. ISSN 1949-2553. 6(33), p. 34358–34374. doi: 10.18632/oncotarget.6024. Full text in Research Archive
  • Johannessen, Bjarne; Sveen, Anita & Skotheim, Rolf Inge (2015). Tin: An R package for transcriptome instability analysis. Cancer Informatics. ISSN 1176-9351. 14, p. 109–112. doi: 10.4137/CIN.S31363.
  • Rounge, Trine Ballestad; Furu, Kari; Skotheim, Rolf Inge; Haugen, Trine B.; Grotmol, Tom & Enerly, Espen (2015). Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs. Molecular Cancer. ISSN 1476-4598. 14(153). doi: 10.1186/s12943-015-0411-4. Full text in Research Archive
  • Brabrand, Sigmund; Johannessen, Bjarne; Axcrona, Ulrika; Kraggerud, Sigrid M.; Berg, Kaja Christine Graue & Bakken, Anne Cathrine [Show all 11 contributors for this article] (2015). Exome sequencing of bilateral testicular germ cell tumors suggests independent development lineages. Neoplasia. ISSN 1522-8002. 17(2), p. 167–174. doi: 10.1016/j.neo.2014.12.005.
  • Bruun, Jarle; Kolberg, Matthias; Ahlquist, Terje Cruickshank; Røyrvik, Ellen Christine; Nome, Torfinn & Leithe, Edward [Show all 18 contributors for this article] (2015). Regulator of chromosome condensation 2 identifies high-risk patients within both major phenotypes of colorectal cancer. Clinical Cancer Research. ISSN 1078-0432. 21(16), p. 3759–3770. doi: 10.1158/1078-0432.CCR-14-3294.
  • Hoff, Andreas Midbøe; Johannessen, Bjarne; Alagaratnam, Sharmini; Zhao, Sen; Nome, Torfinn & Løvf, Marthe [Show all 11 contributors for this article] (2015). Novel RNA variants in colorectal cancers. OncoTarget. ISSN 1949-2553. 6(34), p. 36587–36602. doi: 10.18632/oncotarget.5500.
  • Kolberg, Matthias; Høland, Maren; Lind, Guro Elisabeth; Ågesen, Trude Holmeide; Skotheim, Rolf Inge & Hall, Kirsten Sundby [Show all 11 contributors for this article] (2015). Protein expression of BIRC5, TK1, and TOP2A in malignant peripheral nerve sheath tumours - A prognostic test after surgical resection. Molecular Oncology. ISSN 1574-7891. 9(6), p. 1129–1139. doi: 10.1016/j.molonc.2015.02.005.
  • Mesquita, Diana; Barros-Silva, João D.; Santos, Joana; Skotheim, Rolf Inge; Lothe, Ragnhild A & Paulo, Paula [Show all 7 contributors for this article] (2015). Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts. OncoTarget. ISSN 1949-2553. 6(7), p. 5217–5236. doi: 10.18632/oncotarget.2847.
  • Vedeld, Hege Marie; Skotheim, Rolf Inge; Lothe, Ragnhild A & Lind, Guro Elisabeth (2014). The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer. Epigenetics. ISSN 1559-2294. 9(3), p. 346–350. doi: 10.4161/epi.27582.
  • Sveen, Anita; Johannessen, Bjarne; Teixeira, Manuel; Lothe, Ragnhild A & Skotheim, Rolf Inge (2014). Transcriptome instability as a molecular pan-cancer characteristic of carcinomas. BMC Genomics. ISSN 1471-2164. 15(1). doi: 10.1186/1471-2164-15-672.
  • Løvf, Marthe; Nome, Torfinn; Bruun, Jarle; Eknæs, Mette; Bakken, Anne Cathrine & Mpindi, John-Patrick [Show all 12 contributors for this article] (2014). A novel transcript, VNN1-AB, as a biomarker for colorectal cancer. International Journal of Cancer. ISSN 0020-7136. 135(9), p. 2077–2084. doi: 10.1002/ijc.28855.
  • Oppelt, Angela; Haugsten, Ellen Margrethe; Zech, Tobias; Danielsen, Håvard Emil; Sveen, Anita & Lobert, Viola Helene [Show all 8 contributors for this article] (2014). PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. Biochemical Journal. ISSN 0264-6021. 461(3), p. 383–390. doi: 10.1042/BJ20140132.
  • Smebye, Marianne Lislerud; Sveen, Anita; Haugom, Lisbeth; Davidson, Ben; Tropé, Claes Gøran & Lothe, Ragnhild A [Show all 9 contributors for this article] (2014). Chromosome 19 rearrangements in ovarian carcinomas: Zinc finger genes are particularly targeted. Genes, Chromosomes and Cancer. ISSN 1045-2257. 53(7), p. 558–567. doi: 10.1002/gcc.22166.
  • Nome, Torfinn; Hoff, Andreas Midbøe; Bakken, Anne Cathrine; Rognum, Torleiv Ole; Nesbakken, Arild & Skotheim, Rolf Inge (2014). High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: Novel fusion partner and splice variants. PLOS ONE. ISSN 1932-6203. 9(3). doi: 10.1371/journal.pone.0091264. Full text in Research Archive
  • Avery, Stuart; Hirst, Adam J.; Baker, Duncan; Lim, Chin Yan; Alagaratnam, Sharmini & Skotheim, Rolf I. [Show all 12 contributors for this article] (2013). BCL-XL mediates the strong selective advantage of a 20q11.21 amplification commonly found in human embryonic stem cell cultures. Stem Cell Reports. ISSN 2213-6711. 1(5), p. 379–386. doi: 10.1016/j.stemcr.2013.10.005.
  • Sveen, Anita; Nesbakken, Arild; Ågesen, Trude Holmeide; Guren, Marianne; Tveit, Magne Kjell & Skotheim, Rolf Inge [Show all 7 contributors for this article] (2013). Anticipating the Clinical Use of Prognostic Gene Expression-Based Tests for Colon Cancer Stage II and III: Is Godot Finally Arriving? Clinical Cancer Research. ISSN 1078-0432. 19(24), p. 6669–6677. doi: 10.1158/1078-0432.CCR-13-1769.
  • Paulo, Paula; Bakken, Anne Cathrine; Cerveira, Nuno; Løvf, Marthe; Henrique, Rui & Jerónimo, Carmen [Show all 10 contributors for this article] (2013). Novel 5 ' Fusion Partners of ETV1 and ETV4 in Prostate Cancer. Neoplasia. ISSN 1522-8002. 15(7), p. 720–726. doi: 10.1593/neo.13232.
  • Løvf, Marthe; Thomassen, Gard O Sundby; Mertens, Fredrik; Cerveira, Nuno; Teixeira, Manuel & Lothe, Ragnhild A [Show all 7 contributors for this article] (2013). Assessment of Fusion Gene Status in Sarcomas Using a Custom Made Fusion Gene Microarray. PLOS ONE. ISSN 1932-6203. 8(8). doi: 10.1371/journal.pone.0070649.
  • Nome, Torfinn; Thomassen, Gard O Sundby; Bruun, Jarle; Ahlquist, Terje Cruickshank; Bakken, Anne Cathrine & Hoff, Andreas Midbøe [Show all 17 contributors for this article] (2013). Common fusion transcripts identified in colorectal cancer cell lines by high throughput RNA sequencing. Translational Oncology. ISSN 1944-7124. 6(5), p. 546–553. doi: 10.1593/tlo.13457. Full text in Research Archive
  • Chung, Charles C.; Kanetsky, Peter A.; Wang, Zhaoming; Hildebrandt, Michelle A.T.; Koster, Roelof & Skotheim, Rolf Inge [Show all 30 contributors for this article] (2013). Meta-analysis identifies four new loci associated with testicular germ cell tumor. Nature Genetics. ISSN 1061-4036. 45(6), p. 680–685. doi: 10.1038/ng.2634.
  • Schumacher, Frecrick R.; Wang, Zhaoming; Skotheim, Rolf Inge; Koster, Roelof; Chung, Charles C. & Hildebrandt, Michelle A.T. [Show all 35 contributors for this article] (2013). Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23. Human Molecular Genetics. ISSN 0964-6906. 22(13), p. 2748–2753. doi: 10.1093/hmg/ddt109.
  • Kraggerud, Sigrid M.; Høi-Hansen, Christina E.; Alagaratnam, Sharmini; Skotheim, Rolf Inge; Abeler, Vera Maria & Rajpert-De Meyts, Ewa [Show all 7 contributors for this article] (2013). Molecular characteristics of malignant ovarian germ cell tumors and comparison with testicular counterparts : implications for pathogenesis. Endocrine reviews. ISSN 0163-769X. 34(3), p. 339–376. doi: 10.1210/er.2012-1045.
  • Alagaratnam, Sharmini; Harrison, Neil; Bakken, Anne Cathrine; Hoff, Andreas Midbøe; Jones, Mark & Sveen, Anita [Show all 10 contributors for this article] (2013). Transforming Pluripotency: An Exon-Level Study of Malignancy-Specific Transcripts in Human Embryonal Carcinoma and Embryonic Stem Cells. Stem Cells and Development. ISSN 1547-3287. 22(7), p. 1136–1146. doi: 10.1089/scd.2012.0369.
  • Camões, Maria J; Paulo, Paula; Ribeiro, Franclim R; Barros-Silva, Joao D.; Almeida, Mafalda & Costa, Vera L [Show all 12 contributors for this article] (2012). Potential Downstream Target Genes of Aberrant ETS Transcription Factors Are Differentially Affected in Ewing's Sarcoma and Prostate Carcinoma. PLOS ONE. ISSN 1932-6203. 7(11). doi: 10.1371/journal.pone.0049819.
  • Sveen, Anita; Ågesen, Trude Holmeide; Nesbakken, Arild; Meling, Gunn Iren; Rognum, Torleiv Ole & Liestøl, Knut [Show all 8 contributors for this article] (2012). ColoGuidePro: A Prognostic 7-Gene Expression Signature for Stage III Colorectal Cancer Patients. Clinical Cancer Research. ISSN 1078-0432. 18(21), p. 6001–6010. doi: 10.1158/1078-0432.CCR-11-3302.
  • Paulo, Paula; Ribeiro, Franclim R; Santos, Joana; Mesquita, Diana; Almeida, Mafalda & Barros-Silva, Joao D. [Show all 14 contributors for this article] (2012). Molecular Subtyping of Primary Prostate Cancer Reveals Specific and Shared Target Genes of Different ETS Rearrangements. Neoplasia. ISSN 1522-8002. 14(7), p. 600–+. doi: 10.1593/neo.12600.
  • Celestino, Ricardo; Sigstad, Eva; Løvf, Marthe; Thomassen, Gard O Sundby; Kotanska-Grøholt, Krystyna & Jørgensen, Lars Hilmar [Show all 13 contributors for this article] (2012). Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes. Genes, Chromosomes and Cancer. ISSN 1045-2257. 51(12), p. 1154–1164. doi: 10.1002/gcc.22003.
  • Ågesen, Trude Holmeide; Sveen, Anita; Merok, Marianne Aarstad; Lind, Guro Elisabeth; Nesbakken, Arild & Skotheim, Rolf Inge [Show all 7 contributors for this article] (2012). ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis. Gut. ISSN 0017-5749. 61(11), p. 1560–1567. doi: 10.1136/gutjnl-2011-301179.
  • Paulo, Paula; Barros-Silva, Joao D.; Ribeiro, Franclim R; Ramalho-Carvalho, Joao; Jeronimo, Carmen & Henrique, Rui [Show all 10 contributors for this article] (2012). FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer. Genes, Chromosomes and Cancer. ISSN 1045-2257. 51(3), p. 240–249. doi: 10.1002/gcc.20948.
  • Matheu, Ander; Collado, Manuel; Wise, Clare; Manterola, Lorea; Cekaite, Lina & Tye, Angela J. [Show all 16 contributors for this article] (2012). Oncogenicity of the Developmental Transcription Factor Sox9. Cancer Research. ISSN 0008-5472. 72(5), p. 1301–1315. doi: 10.1158/0008-5472.CAN-11-3660.
  • Sveen, Anita; Bakken, Anne Cathrine; Ågesen, Trude Holmeide; Lind, Guro Elisabeth; Nesbakken, Arild & Nordgård, Oddmund [Show all 10 contributors for this article] (2012). The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer. International Journal of Cancer. ISSN 0020-7136. 131(6), p. 1479–1485. doi: 10.1002/ijc.27399.
  • Cekaite, Lina; Rantala, Juha K.; Bruun, Jarle; Guriby, Marianne; Ågesen, Trude Holmeide & Danielsen, Stine Aske [Show all 11 contributors for this article] (2012). MiR-9,-31, and-182 Deregulation Promote Proliferation and Tumor Cell Survival in Colon Cancer. Neoplasia. ISSN 1522-8002. 14(9), p. 868–U126. doi: 10.1593/neo.121094.
  • Nyquist, Kaja Beate; Panagopoulos, Ioannis; Thorsen, Jim; Haugom, Lisbeth; Gorunova, Ludmila & Bjerkehagen, Bodil [Show all 13 contributors for this article] (2012). Whole-Transcriptome Sequencing Identifies Novel IRF2BP2-CDX1 Fusion Gene Brought about by Translocation t(1;5)(q42;q32) in Mesenchymal Chondrosarcoma. PLOS ONE. ISSN 1932-6203. 7(11). doi: 10.1371/journal.pone.0049705.
  • Sveen, Anita; Ågesen, Trude Holmeide; Nesbakken, Arild; Rognum, Torleiv Ole; Lothe, Ragnhild A & Skotheim, Rolf Inge (2011). Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival. Genome Medicine. ISSN 1756-994X. 3(5). doi: 10.1186/gm248.
  • Alagaratnam, Sharmini; Lind, Guro Elisabeth; Kraggerud, Sigrid M.; Lothe, Ragnhild A & Skotheim, Rolf Inge (2011). The testicular germ cell tumour transcriptome. International Journal of Andrology. ISSN 0105-6263. 34(4pt2), p. e133–e151. doi: 10.1111/j.1365-2605.2011.01169.x.
  • Ågesen, Trude Holmeide; Berg, Marianne; Clancy, Trevor; Thiis-Evensen, Espen; Cekaite, Lina & Lind, Guro Elisabeth [Show all 16 contributors for this article] (2011). CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer. Genes and Immunity. ISSN 1466-4879. 12(8), p. 653–662. doi: 10.1038/gene.2011.43.
  • Danielsen, Stine Aske; Cekaite, Lina; Ågesen, Trude Holmeide; Sveen, Anita; Nesbakken, Arild & Thiis-Evensen, Espen [Show all 9 contributors for this article] (2011). Phospholipase C Isozymes Are Deregulated in Colorectal Cancer - Insights Gained from Gene Set Enrichment Analysis of the Transcriptome. PLOS ONE. ISSN 1932-6203. 6(9). doi: 10.1371/journal.pone.0024419.
  • Lind, Guro Elisabeth; Danielsen, Stine Aske; Ahlquist, Terje Cruickshank; Merok, Marianne Aarstad; Andresen, Kim & Skotheim, Rolf Inge [Show all 14 contributors for this article] (2011). Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas. Molecular Cancer. ISSN 1476-4598. 10. doi: 10.1186/1476-4598-10-85.
  • Ribeiro, Franclim R; Paulo, Paula; Costa, Vera L; Barros-Silva, Joao D.; Ramalho-Carvalho, Joao & Jeronimo, Carmen [Show all 11 contributors for this article] (2011). Cysteine-Rich Secretory Protein-3 (CRISP3) Is Strongly Up-Regulated in Prostate Carcinomas with the TMPRSS2-ERG Fusion Gene. PLOS ONE. ISSN 1932-6203. 6(7). doi: 10.1371/journal.pone.0022317.
  • Sagona, Antonia; Nezis, Ioannis; Bache, Kristi Cecilie Grønvold; Haglund, Kaisa; Bakken, Anne Cathrine & Skotheim, Rolf Inge [Show all 7 contributors for this article] (2011). A Tumor-Associated Mutation of FYVE-CENT Prevents Its Interaction with Beclin 1 and Interferes with Cytokinesis. PLOS ONE. ISSN 1932-6203. 6(3). doi: 10.1371/journal.pone.0017086.
  • Løvf, Marthe; Thomassen, Gard O Sundby; Bakken, Anne Cathrine; Celestino, Ricardo; Fioretos, Thoas & Lind, Guro Elisabeth [Show all 8 contributors for this article] (2011). Fusion Gene Microarray Reveals Cancer Type-Specificity Among Fusion Genes. Genes, Chromosomes and Cancer. ISSN 1045-2257. 50(5), p. 348–357. doi: 10.1002/gcc.20860.
  • Costa, Vera L; Henrique, Rui; Danielsen, Stine Aske; Duarte-Pereira, S; Eknæs, Mette & Skotheim, Rolf Inge [Show all 13 contributors for this article] (2010). Three Epigenetic Biomarkers, GDF15, TMEFF2, and VIM, Accurately Predict Bladder Cancer from DNA-Based Analyses of Urine Samples. Clinical Cancer Research. ISSN 1078-0432. 16(23), p. 5842–5851. doi: 10.1158/1078-0432.CCR-10-1312.
  • Auensen, Espen; Skotheim, Rolf Inge; Schjølberg, Aasa Rambæk; Røislien, Jo; Lothe, Ragnhild A & Clausen, Ole Petter Fraas (2010). Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors. Journal of Carcinogenesis. ISSN 0974-6773. 9(1), p. 1–1. doi: 10.4103/1477-3163.60358.
  • Micci, Francesca; Skotheim, Rolf Inge; Haugom, Lisbeth; Weimer, J; Eibak, Anne Mette E. & Abeler, Vera Maria [Show all 10 contributors for this article] (2010). Array-CGH Analysis of Microdissected Chromosome 19 Markers in Ovarian Carcinoma Identifies Candidate Target Genes. Genes, Chromosomes and Cancer. ISSN 1045-2257. 49(11), p. 1046–1053. doi: 10.1002/gcc.20813.
  • Sagona, Antonia; Nezis, Jonnis P; Pedersen, Nina Marie; Liestøl, Knut; Poulton, J & Rusten, Tor Erik [Show all 9 contributors for this article] (2010). PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody. Nature Cell Biology. ISSN 1465-7392. 12(4), p. 362–U140. doi: 10.1038/ncb2036.
  • Berg, Marianne; Ågesen, Trude Holmeide; Thiis-Evensen, Espen; Merok, Marianne Aarstad; Teixeira, Manuel & Vatn, Morten H [Show all 9 contributors for this article] (2010). Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci. Molecular Cancer. ISSN 1476-4598. 9. doi: 10.1186/1476-4598-9-100.
  • Brekke, Helge Roar; Ribeiro, Franclim R; Kolberg, Matthias; Ågesen, Trude H.; Lind, Guro Elisabeth & Eknæs, Mette [Show all 15 contributors for this article] (2010). Genomic Changes in Chromosomes 10, 16, and X in Malignant Peripheral Nerve Sheath Tumors Identify a High-Risk Patient Group. Journal of Clinical Oncology. ISSN 0732-183X. 28(9), p. 1573–1582. doi: 10.1200/JCO.2009.24.8989.
  • Skotheim, Rolf Inge; Thomassen, Gard O Sundby; Eken, Marthe; Lind, Guro Elisabeth; Micci, Francesca & Ribeiro, FR [Show all 11 contributors for this article] (2009). A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. Molecular Cancer. ISSN 1476-4598. 8. doi: 10.1186/1476-4598-8-5. Full text in Research Archive
  • Micci, Francesca; Weimer, J; Haugom, L; Skotheim, Rolf Inge; Grunewald, R & Abeler, Vera Maria [Show all 11 contributors for this article] (2009). Reverse Painting of Microidissected Chromosome 19 Markers in Ovarian Carcinoma Identifies a Complex Rearrangement Map. Genes, Chromosomes and Cancer. ISSN 1045-2257. 48(2), p. 184–193. doi: 10.1002/gcc.20628.
  • Godmann, M; Gashaw, I; Eildermann, K; Schweyer, S; Bergmann, M & Skotheim, Rolf Inge [Show all 7 contributors for this article] (2009). The pluripotency transcription factor Kruppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma. Molecular human reproduction. ISSN 1360-9947. 15(8), p. 479–488. doi: 10.1093/molehr/gap040.
  • Brekke, Helge Roar; Kolberg, Matthias; Skotheim, Rolf Inge; Hall, Kirsten Sundby; Bjerkehagen, Bodil & Risberg, Bjørn [Show all 13 contributors for this article] (2009). Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors. Neuro-Oncology. ISSN 1522-8517. 11(5), p. 514–528. doi: 10.1215/15228517-2008-127.
  • Alagaratnam, Sharmini; Hardy, JR; Lothe, Ragnhild A; Skotheim, Rolf Inge & Byrne, JA (2009). TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours. Molecular and Cellular Endocrinology. ISSN 0303-7207. 306(1-2), p. 75–80. doi: 10.1016/j.mce.2008.10.043.
  • Ahlquist, Terje Cruickshank; Lind, Guro Elisabeth; Costa, Vera L; Meling, Gunn Iren; Vatn, Morten H & Hoff, Geir S [Show all 10 contributors for this article] (2008). Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers. Molecular Cancer. ISSN 1476-4598. 7. doi: 10.1186/1476-4598-7-94.

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  • Rajpert-De Meyts, Ewa & Skotheim, Rolf I. (2018). Complex Polygenic Nature of Testicular Germ Cell Cancer Suggests Multifactorial Aetiology. European Urology. ISSN 0302-2838. 73(6), p. 832–833. doi: 10.1016/j.eururo.2018.02.023.
  • Rounge, Trine Ballestad; Furu, Kari; Skotheim, Rolf Inge; Haugen, Trine B.; Enerly, Espen & Grotmol, Tom (2015). Small RNA profiling of human testicular cancer tissue samples shows abundant tRNA fragments and global loss of piRNA.
  • Skotheim, Rolf Inge; Nome, Torfinn; Thomassen, Gard O Sundby; Johannessen, Bjarne; Bakken, Anne Cathrine & Bruun, Jarle [Show all 10 contributors for this article] (2012). Identification of Fusion Transcripts in Colorectal Cancer by Combined RNA-seq and Exon Microarray Analyses. European Journal of Cancer. ISSN 0959-8049. 48, p. S121–S121.
  • Skotheim, Rolf Inge; Meza-Zepeda, Leonardo Andrés; Hovig, Eivind; Lønning, Per Eystein; Lothe, Ragnhild A & Myklebost, Ola (2012). Genomsekvensering for persontilpasset kreftbehandling. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 132, p. 2406–2408. doi: 10.4045/tidsskr.12.0784.
  • Ågesen, Trude Holmeide; Berg, Marianne; Cekaite, Lina; Thiis-Evensen, Espen; Merok, Marianne Aarstad & Nesbakken, Arild [Show all 8 contributors for this article] (2010). Transcriptional profiling of early onset colorectal cancer identifies CLC as a potential cancer susceptibility gene. European Journal of Cancer. ISSN 0959-8049. 8(5), p. 205–205.
  • Paulo, Paula; Barros-Silva, João D.; Ribeiro, Franclim R; Ramalho-Carvalho, João; Mesquita, Bárbara & Jerónimo, Carmen [Show all 10 contributors for this article] (2010). Quantitative expression analysis of nine ETS transcription factors and of the MYC and PTEN genes in a consecutive series of 200 prostate carcinomas. European Journal of Cancer. ISSN 0959-8049. 8(5), p. 169–169.
  • Kolberg, Matthias; Ågesen, Trude Holmeide; Brekke, Helge Roar; Skotheim, Rolf Inge; Hall, Kirsten Sundby & van den Berg, Eva [Show all 10 contributors for this article] (2010). Prognostic value of gene expression targeted by gain of 17q sequences in malignant peripheral nerve sheath tumours. European Journal of Cancer. ISSN 0959-8049. 8(5), p. 32–32.
  • Cekaite, Lina; Danielsen, Stine Aske; Ågesen, Trude Holmeide; Sveen, Anita; Thiis-Evensen, Espen & Merok, Marianne Aarstad [Show all 9 contributors for this article] (2010). New insights into molecular pathways of colorectal cancer from genome-level expression data. European Journal of Cancer. ISSN 0959-8049. 8(5), p. 223–223.
  • Berg, Marianne; Ågesen, Trude Holmeide; Danielsen, Stine Aske; Ahlquist, Terje Cruickshank; Merok, Marianne Aarstad & Mala, Tom [Show all 10 contributors for this article] (2010). Genome copy number variation and gene mutation profiling show different somatic development of colorectal cancers in young and elderly patients. European Journal of Cancer. ISSN 0959-8049. 8(5), p. 201–202.
  • Løvf, Marthe; Thomassen, Gard O Sundby; Lind, Guro Elisabeth; Lothe, Ragnhild A & Skotheim, Rolf Inge (2010). An oligo microarray design for detection of known and putative oncogenic fusion transcripts. European Journal of Cancer. ISSN 0959-8049. 8(5), p. 199–199.
  • Burum-Auensen, E; Skotheim, Rolf Inge; Schjolberg, AR; Roislien, JO; Lothe, Ragnhild A & Clausen, Ole Petter Fraas (2009). Spindle proteins show significant changes in expression during germ cell carcinogenesis and are differently expressed in the subgroups of testicular germ cell cancer. APMIS - Journal of Pathologiy, Microbiology and Immunology. ISSN 0903-4641. 117(3), p. 236–237.
  • Skotheim, Rolf Inge; Eken, Marthe; Thomassen, Gard O Sundby; Lind, Guro Elisabeth & Lothe, Ragnhild A (2009). A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis. European Journal of Cancer. ISSN 0959-8049. 7(2), p. 147–148.
  • Berg, Marianne; Agesen, TH; Nesbakken, Arild; Thiis-Evensen, E; Lothe, Ragnhild A & Skotheim, Rolf Inge (2008). DNA copy number profiling of early onset colorectal cancer. Cellular Oncology. ISSN 1570-5870. 30(2), p. 153–154.

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Published June 3, 2014 10:04 AM - Last modified Nov. 28, 2022 12:37 PM