Carl Henrik Gørbitz

Image of Carl Henrik Gørbitz
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Phone +47-22855460
Room VU 64
Username
Visiting address Sem Sælands vei 26 0371 OSLO
Postal address Postboks 1033 Blindern 0315 OSLO
Other affiliations Department of Chemistry

Academic Interests

We are studying the crystal structures of various amino acids and peptides, either alone or in complexes with other selected compounds.

We do systematic investigations of the way these molecules interact with each other. In this we become capable of using them as tools in crystal engineering of new classes of organic nanomaterials. These nanomaterials may be used for storageand slow release of bioactive substances by adsorption and desorption, as sensors, artificial receptors, in catalysts etc.

Single crystal X-ray diffraction is our main experimental method, but it is supplemented by a range of different model calculations, ab initio structure prediction,retrieval of information from structural databases and investigations carried out under extreme conditions (high pressure and/or temperature) at the University of Oslo or in cooperation with national and international partners.

 

Tags: Chemistry, Biological chemistry

Publications

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  • Antonsen, Simen Gjelseth; Stenstrøm, Yngve H.; Hansen, Trond Vidar; Gallantree-Smith, Harrison Christopher; Nolsøe, Jens Mortansson Jelstrup & Görbitz, Carl Henrik (2017). Total synthesis based on the originally claimed structure of mucosin.
  • Nolsøe, Jens Mortansson Jelstrup; Gallantree-Smith, Harrison; Antonsen, Simen Gjelseth; Gorbitz, Carl Henrik; Hansen, Trond Vidar & Stenstrøm, Yngve (2017). Total synthesis based on the originally claimed structure of mucosin.
  • Alebachew, Fassil & Görbitz, Carl Henrik (2016). X-ray structural investigation of protected oligopeptides as model compounds for the development of aquaporin inhibitors .
  • Day, Graeme M. & Gorbitz, Carl Henrik (2016). Introduction to the special issue on crystal structure prediction. Acta Crystallographica. Section B: Structural Science, Crystal Engineering and Materials.  ISSN 2052-5192.  72(4), s 435- 436 . doi: 10.1107/S2052520616012348
  • Zawadzka, Malgorzata Elzbieta; Wilson, Steven Ray Haakon & Görbitz, Carl Henrik (2016). Unravelling nature s sunglasses – Identifying the compound that protects bird eyes .
  • Jemterud, Torkild; Wenn, Camilla Cecilie; Holm, Sverre & Gorbitz, Carl Henrik (2015, 25. september). Tidskapsler - og andre spørsmål . [Radio].  NRK Ekko - Abels tårn.
  • Lausund, Kristian Blindheim; Wilson, Steven Ray Haakon; Gorbitz, Carl Henrik; Lundanes, Elsa & Nilsen, Ola (2015). Deposition of organic-inorganic hybrid films of Zr-1,4-BDC by ALD.
  • Lausund, Kristian Blindheim; Wilson, Steven Ray Haakon; Gorbitz, Carl Henrik; Lundanes, Elsa & Nilsen, Ola (2015). Nano-filters for Blood Sample Analysis.
  • Lausund, Kristian Blindheim; Wilson, Steven Ray Haakon; Gorbitz, Carl Henrik; Lundanes, Elsa & Nilsen, Ola (2015). Nano-filters for blood sample analysis.
  • Lausund, Kristian Blindheim; Wilson, Steven Ray Haakon; Gorbitz, Carl Henrik; Lundanes, Elsa & Nilsen, Ola (2015). Porous inorganic-organic hybrid materials by ALD.
  • Vogt, Yngve; Thorbjørnsrud, Helen Vikdal; Burschowsky, Daniel; Gorbitz, Carl Henrik & Krengel, Ute (2015). Molekylforskning kan gi ny medisin mot tuberkulose. Apollon : Forskningsmagasin for Universitetet i Oslo.  ISSN 0803-6926.
  • Hammami, Amir; Høiland, Klaus & Gorbitz, Carl Henrik (2014, 28. november). Abels Tårn. [Radio].  EKKO, NRK P2.
  • Holmsen, Marte Sofie; Gorbitz, Carl Henrik; Øien, Sigurd & Tilset, Mats (2014). Synthesis, Structure and Dynamics of New Rh(III) N-Heterocyclic Carbene Complexes.
  • Holmsen, Marte Sofie; Gorbitz, Carl Henrik; Øien, Sigurd & Tilset, Mats (2014). Synthesis, structure and dynamics of new Rh(III) N-heterocyclic carbene complexes.
  • Holmsen, Marte Sofie; Gorbitz, Carl Henrik; Øien, Sigurd & Tilset, Mats (2014). Synthesis, structure and dynamics of new Rh(III) N-heterocyclic carbene complexes.
  • Holmsen, Marte Sofie; Gørbitz, Carl Henrik; Øien, Sigurd & Tilset, Mats (2014). Synthesis, structure and dynamics of new Rh(III) N-heterocyclic carbene complexes.
  • Yadav, Vitthal Narayan; Görbitz, Carl Henrik & Bonge-Hansen, Tore (2013). Design and Synthesis of Microporous Dipeptide Structures and Guanidinium-carboxylate-based Organic Supramolecular Materials. .
  • Eilertsen, Einar Andre & Görbitz, Carl Henrik (2012). Synthesis of zeolites with controlled active sites and topology .
  • Schoultz, Bent Wilhelm & Görbitz, Carl Henrik (2012). Automated radiosynthesis of tracers for use in positron emission tomography .
  • Askarieh, Glareh; Görbitz, Carl Henrik; Knight, Stefan & Johansson, Jan (2011). Coupled folding and binding - Studies of BRICHOS and spider silk proteins. .
  • Gebreslasie, Hadgu G; Jacobsen, Øyvind & Gorbitz, Carl Henrik (2011). N-(tert-Butoxycarbonyl)-O-allyl-L-seryl-alpha-aminoisobutyryl-L-valine methyl ester: a protected tripeptide with an allylated serine residue. Acta Crystallographica Section C: Crystal Structure Communications.  ISSN 0108-2701.  67, s O359- O363 . doi: 10.1107/S0108270111029647
  • Siah, Huey San Melanie; Gundersen, Lise-Lotte & Gorbitz, Carl Henrik (2011). NMR and X-ray structural studies of 3-benzyl-8-bromoadenine.
  • Roggen, Heidi; Bohlin, Lars; Burman, Robert; Charnock, Colin; Felth, Jenny; Gorbitz, Carl Henrik; Larsson, Rolf; Tamm, Toomas & Gundersen, Lise-Lotte (2010). Synthesis, structure, reactivity and biological activity of agelasine analogs and synthetic intermediates.
  • Roggen, Heidi; Tamm, Toomas; Neier, Liina; Gorbitz, Carl Henrik & Gundersen, Lise-Lotte (2010). Tautomerism of 6-(Methoxyamino)-purines; Theoretical Calculations, NMR Experiments and X-ray Crystallography.
  • Tamm, Toomas; Neier, Liina; Gundersen, Lise-Lotte; Roggen, Heidi & Gorbitz, Carl Henrik (2010). Modeling of tautomeric equilibria in agelasine precursors.
  • Andersson, K. Kristoffer; Hsiao, Ya-Wen; Gorbitz, Carl Henrik; Ryde, Ulf & Hersleth, Hans-Petter (2009). Structural studies of the intermediates in the reaction between myoglobin and peroxides; effects of cryoradiolytic reduction. NBS-nytt.  ISSN 0801-3535.  s 65- 65
  • Hersleth, Hans-Petter; Hsiao, Ya-Wen; Nilsson, Kristina; Rydberg, P; Rod, T. H.; Røhr, Åsmund Kjendseth; Ryde, Ulf; Gorbitz, Carl Henrik & Andersson, K. Kristoffer (2009). Structural studies of the intermediates in the reaction between myoglobin and peroxides.
  • Hersleth, Hans-Petter; Hsiao, Ya-Wen; Ryde, Ulf; Gorbitz, Carl Henrik & Andersson, K. Kristoffer (2009). ChemInform Abstract: The Influence of X-Rays on the Structural Studies of Peroxide-Derived Myoglobin Intermediates. ChemInform.  ISSN 0931-7597.  40(2) . doi: 10.1002/chin.200902274
  • Hersleth, Hans-Petter; Hsiao, Ya-Wen; Gorbitz, Carl Henrik; Ryde, Ulf & Andersson, K. Kristoffer (2008). Structural Studies of the Intermediates in the Reaction Between Myoglobin and Peroxides.
  • Hersleth, Hans-Petter; Hsiao, Ya-Wen; Gorbitz, Carl Henrik; Ryde, Ulf & Andersson, K. Kristoffer (2008). Structural studies of the intermediate in the reaction between myoglobin and peroxides.
  • Hersleth, Hans-Petter; Hsiao, Ya-Wen; Ryde, Ulf; Gorbitz, Carl Henrik & Andersson, K. Kristoffer (2008). On the Quest for Metalloprotein Reaction Intermediates in the Radiation Damage Landscape of Protein Crystallography. NBS-nytt.  ISSN 0801-3535.  s 34- 34
  • Stølen, Svein; Gorbitz, Carl Henrik; Omtvedt, Jon Petter & Ødegaard, Knut Jørgen Røed (2008, 25. februar). Verdt å vite spesial: Grunnstoffene og periodesystemet. [Radio].  NRK P2.
  • Andersson, K. Kristoffer; Agasøster, Armelle Varnier; Harbitz, Espen; Røhr, Åsmund Kjendseth; Sørlie, Morten; Gorbitz, Carl Henrik & Hersleth, Hans-Petter (2007). Reactive complexes in myoglobin and nitric oxide synthase INOR 458.

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Published Nov. 11, 2010 9:00 AM - Last modified Sep. 24, 2012 11:47 AM