Services, research and activities

Collaborative Research

A  collaborative academic or industrial user is one who collaborate with the scientific leaders of the NMR Center; Frode Rise with the intent of producing a joint scientific product (e.g., journal article, technical report, book, conference abstract/presentation materials or a patent).

Independent academic research from a user at University of Oslo at our premises

An independent academic user from UiO is a person who has no plans to collaborate with the scientific leaders of the NMR Center nor having any intention of producing a joint scientific product (e.g., journal article, technical report, book, conference abstract/presentation or patent application) now or in the near future. 

Independent users from the Department of Chemistry and the School of Pharmacy at the University of Oslo are given sufficient training in how to use the 200, 300 and 400 MHz NMR-instruments in the course KJM-MENA 4010 Experimental methods module one NMR: which is given in the beginning of every semester. Other independent academic users from the University of Oslo are mainly supposed to have obtained sufficient experience elsewhere. However anyone eligible to register for the courses KJM-MENA 4010 Experimental methods module one NMR and KJM 5250 Organic NMR spectroscopy are advised to do so.  Independent academic users from other academic institutions than the School of Pharmacy and the Department of Chemistry at the University of Oslo are billed 100 NOK for each instrument hour when the user acquire the data herself/himself on the DPX200, DPX300 and AV400 NMR instruments. The hourly fee on the DRX 500 instrument is 200 NOK.On the AV600 NMR instrument a fee of 250 NOK is charged. These payments are used solely to pay for liquid helium, liquid nitrogen, spare parts and service.  

Independent academic users from UiO with insufficient NMR-training are prohibited from using the NMR-instruments for safety reasons. All academic projects at our premises including operator/engineer assistance must include a member of the permanent academic staff of the Department of Chemistry, University of Oslo. Such projects must be put forward through this member of the permanent academic staff at Department of Chemistry to the personnel of the NMR-Center. This person will the be a co-author of all publications resulting from the NMR research. The NMR Center has a very limited work capacity concerning operator and engeneering assistance and this resource is strictly reserved for projects involving a publishing member of the permanently hired academic staff at the Department of Chemistry.

Academic service at the Department of Chemistry

Permanantly employed academic personell and their students at the Department of Chemistry, University of Oslo are having the opportunity to submit samples for acquisition of NMR-spectra at the Bruker DRX 500 and AV 600 instruments (e.g. one dimensional 1H and 13C spectra as well as 1D spectra of the other nuclei which can be observed with the available probes, NOESY, ROESY, TOCSY, COSY, 1H-13C HMBC, 1H-13C HSQC, 1H-13C edited HSQC, 1H-13C HMQC, 1H-15N HSQC, 1H-15N HMQC, 1H-15N HMBC, NOEDIF, DEPT45, DEPT90, DEPT135, high and low temperature NMR experiments (only on the Bruker DRX500 instrument due to technical restrictions on the AV600 instrument) and other available experiments as well).  The NMR data are acquired by the NMR instrument operator and Associate Professors and Professors at Department of Chemistry are given paper copies of the spectra.  Master- and doctoral-students as well as post docs at the Department of Chemistry are given the raw NMR data and they are supposed to process and plot the spectra on their own since they have been trained to do this in  the NMR module in the course  KJM-MENA 4010.  Further processing and evaluation of the data is the responsibility of the user unless a Collaborative publishing agreement is reached with the Scientific leader of the NMR Center (see Collaborative Research above). All academic projects which include operator acquisition and plotting assistance must include a member of the permanently hired academic staff of the Department of Chemistry, University of Oslo. The NMR Center has a very limited work capacity concerning operator and engeneering assistance and this resource is strictly reserved for projects involving a member of the permanently hired academic staff at the Department of Chemistry.

Commercial service

Depending upon the availability of laboratory staff and instrument time the NMR-Center offers commercial services. Most of the companies renting our NMR-facilities have employed individuals who previously have been trained at the University of Oslo NMR Center. They acquire NMR data without any assistance. Commercial users with sufficient training sign a contract giving them access to the low field instruments Bruker AVII 400, DPX 200 and DPX 300. NMR spectra are also available at 500 and 600 MHz. At these field strengths you are also purchasing engineering assistance. The price (January 2011) for instrument time is differentiated according to field strength and probe type.

 

200, 300 and 400 MHz:	400 NOK + 25 % VAT pr hour
500 MHz:	600 NOK + 25 % VAT pr hour
600 MHz including cryo probe:	1000 NOK + 25 % VAT pr hour

 

The cost for setting up the experiments of a customer prepared sample including shimming, tuning/matching and a minimal processing of the data (no integration, no calibration of chemical shifts and no insertion of 1D spectra on the sides of the 2D spectra) is costing 1000 NOK + 25 % VAT pr hour. The data is transferred to the customers memory stick or copied to a CD-ROM for further processing, plotting and storage by the customer. 

A more extensive service can sometimes be included; such as sample preparation, integration and calibration of spectra as well as plotting (A4 or A3 paper) of the data with one dimensional spectra on the sides of two dimensional spectra does cost 1000 NOK + 25 % VAT pr hour. This service is not always available due to capacity limitations. The data can be transferred to the customer´s (new and previously unused) memory stick  for further processing and storage by the customer. 

All requests for commercial service shall be directed to the scientific leader of the Center.

Commercial service for academic users from the University of Oslo

Depending upon the availability of staff and instrument time the NMR Center offers commercial services to other University of Oslo institutions than the Department of Chemistry.  The current prices (January 2011) are NOK 400 (+ 25 % VAT) for each instrument hour when the NMR instrument is acquiring data after the experiments setup by the engineer.  The cost for setting up/starting the experiments and processing data is additionally NOK 1000 (+ 25 % VAT) for each personell hour (e.g. a total price of NOK 1400 (+ 25 % VAT ) pr hour for part of the time). All requests concerning commercial service from academic users at the University of Oslo must be directed to the scientific leader of the NMR Center.  

If you cannot afford these prices please include a professor or associate professor from the Department of Chemistry UiO as a collaborator as well as a co-author on all publications in the project and the service will be free of charge (with the obvious limitation that we must have available personnell).

MLS^UIO-service/collaborative projects under the interfaculty supported Molecular Life Science initiaive: A special and limited form of service or collaborative research is sponsored by MLS^UIO for University of Oslo users in the year 2010 solely on the Triple Alliance NMR Instrument - AVII600. Please see EMBIO´s web pages for more information (EMBIO is the predecessor of MLS^UIO.) You can also find the just established web pages belonging to  MLS^UIO. 

Acknowledgment

All users must acknowledge the University of Oslo NMR Center and also acknowledge the Research Council of Norway for financial contribution in connection with the purchase of all NMR instruments except the AV600 instrument which was financed solely by the Faculty of Mathematics and Natural Sciences at the University of Oslo in all publications, patents, books, meeting presentations and so forth resulting from the use of the facilities.

Links

NMR research in the Polymers and Organic Materials Research Group at Department of Chemistry - UiO.  Please contact Professor Eddy Walter Hansen

NMR research at IMBV - UiO

NMR research at UMB

MR research at ISB, NTNU

NMR research at NTNU

NMR research at UiB

NMR research at UiT - Please contact Professor Jon Sigurd Svendsen

NMR research is taking place in GE Healthcare in Oslo, in the  EWOS  company  in Dirdal near Stavanger, at FMC BioPolymer/NovaMatrix in Bærum outside Oslo, at Sintef in Oslo and Sintef in Trondheim and at FFI at Kjeller. If you are in need of obtaining information about whom to contact at these places please contact frode.rise@kjemi.uio.no .