About the project
- Propionate enters GABAergic neurons, inhibits GABA transaminase, causes GABA accumulation and lethargy in a model of propionic acidemia. Cecilie Morland, Anne-Sofie Frøland, Mi Nguyen Pettersen, Jon Storm-Mathisen, Vidar Gundersen, Frode Rise, Bjørnar Hassel. http://www.biochemj.org/content/early/2018/01/16/BCJ20170814
- Uptake and metabolism of fructose by rat neocortical cells in vivo and by isolated nerve terminals in vitro Hassel, Bjornar; Elsais, Ahmed; Froland, Anne-Sofie; Tauboll, Erik; Gjerstad, Leif; Quan, Yi; Dingledine, Raymond; Rise, Frode Journal of Neurochemistry (2015), 133(4), 572-581.
- Nguyen, N. T. H.; Morland, C; Gonzales, S. V.; Rise, F.; Storm-Mathiesen, J; Gundersen, V.; Hassel, B. Propionate increases neuronal histone acetylation, but is metabolized oxidatively by glia. Relevance for propionic acidemia.. Journal of Neurochemistry (2007), 101(3), 806-814.
- Nguyen, N. T. H.; Gonzales, S. V; Rise, F; Hassel, B. Cerebral metabolism of glucose and pyruvate in soman poisoning A (13)C nuclear magnetic resonance spectroscopic study. Neurotoxicology (2007); 28(1):13-18.
Tools
The AVI600 nmr instrument from University of Oslo NMR Center is used in these studies.