Meike Tessa Wortel

Academic interests

In my PhD thesis titled "The Evolution of Metabolic Strategies" I have studied the adaptation of and selection pressures on the metabolism of microorganisms at the VU University in Amsterdam. I joined CEES to research the interactions between species and the effects those interactions can have on evolutionairy outcomes. More specifically, I will study requirements of biological systems that lead to Red Queen evolution—continued evolution driven by biotic interactions—with the analysis of general mathematical models of multiple species communities.

The benefit of evolution in microorganisms is that those can be experimentally tested. Therefore I will apply my knowledge about microbial metabolism to microbial communities to predict Red Queen evolution in microbial systems.

Publications

  • Bosdriesz, Evert; Wortel, Meike Tessa; Haanstra, Jurgen R.; Wagner, Marijke J.; De La Torre Cortes, Pilar & Teusink, Bas (2018). Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux. Scientific Reports.  ISSN 2045-2322.  8(1) . doi: 10.1038/s41598-018-23528-7
  • Palumbo, Pasquale; Vanoni, Marco; Papa, Federico; Busti, Stefano; Wortel, Meike Tessa; Teusink, Bas & alberghina, lilia (2018). An integrated model quantitatively describing metabolism, growth and cell cycle in budding yeast. Communications in Computer and Information Science.  ISSN 1865-0929.  830, s 165- 180 . doi: 10.1007/978-3-319-78658-2_13
  • Wortel, Meike Tessa; Noor, Elad; Ferris, Michael; Bruggeman, Frank J. & Liebermeister, Wolfram (2018). Metabolic enzyme cost explains variable trade-offs between microbial growth rate and yield. PloS Computational Biology.  ISSN 1553-734X.  14(2) . doi: 10.1371/journal.pcbi.1006010
  • Bonachela, Juan; Wortel, Meike Tessa & Stenseth, Nils Christian (2017). Eco-evolutionary Red Queen dynamics regulate biodiversity in a metabolite-driven microbial system. Scientific Reports.  ISSN 2045-2322.  7 . doi: 10.1038/s41598-017-17774-4 Full text in Research Archive.
  • Wortel, Meike Tessa; Bosdriesz, Evert; Teusink, Bas & Bruggeman, Frank J. (2016). Evolutionary pressures on microbial metabolic strategies in the chemostat. Scientific Reports.  ISSN 2045-2322.  6:29503, s 1- 11 . doi: 10.1038/srep29503

View all works in Cristin

  • Wortel, Meike Tessa (2015). The rich evolutionary dynamics of metabolic interactions: Is the Red Queen one of them?.

View all works in Cristin

Published Oct. 27, 2015 10:57 AM - Last modified Oct. 27, 2015 10:57 AM