Tackling long-standing biological questions using the Roche FLX platform
By Tom Gilbert
The advent of 'high-throughput sequencing by synthesis' platforms, such as the Roche FLX that will be opened in Oslo on the 30th, present great advantages with regards to the tackling of many traditional biological questions. Although only commercially released in 2006, a number of high impact papers have already been published that are based on this technology, challenging a range of questions, from the nature of neandertal-human coexistence, to the composition, diversity and spread of microbial communities that are otherwise unanalysable, to the evolution of eusociality. In this talk I will firstly introduce the audience to some of the questions that have so far been investigated in this way. Subsequently I will present unpublished results of studies that we in Copenhagen have produced, investigating the taxanomic relationship of extinct woolly mammoths and rhinos. To conclude, I will outline questions that the FLX might render answerable in the near future.
Program for the official opening of the Roche 454 FLX sequencer at the Centre for Ecological and Evolutionary Synthesis
Nov 30, 2007, 13:15-14:30
Aud 3 in Kristine Bonnevies Hus, University of Oslo, Blindern.
13:15-13:20: "Centre for Ecological and Evolutionary Synthesis CEES-CoE and its Roche GS FLX genome sequencer" by Nils Chr. Stenseth: about CEES
13:20-13:40: "Roche FLX Genome Sequencer - technology and applications" by Jens Buhrmester(Roche Diagnostics GmbH)
13:40-13:50: "The Roche GS FLX genome sequencer as a FUGE platform at CEES" by Kjetill S. Jakobsen
13:50-14:30: Key-note lecture: Tom Gilbert (Dept of Biology, University of Copenhagen)- "Tackling long-standing biological questions using the Roche FLX platform"
All are most welcome,
Nils Chr. Stenseth (Chair of CEES)