The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): Illuminating the Functional Diversity of Eukaryotic Life in the Oceans through Transcriptome Sequencing

Keeling et al. (Kjetill Jakobsen) in PLOS Biology

From the paper

Microbial ecology is plagued by prob- lems of an abstract nature. Cell sizes are so small and population sizes so large that both are virtually incomprehensible. Nich- es are so far from our everyday experience as to make their very definition elusive. Organisms that may be abundant and critical to our survival are little under- stood, seldom described and/or cultured, and sometimes yet to be even seen. One way to confront these problems is to use data of an even more abstract nature: molecular sequence data. Massive envi- ronmental nucleic acid sequencing, such as metagenomics or metatranscriptomics, promises functional analysis of microbial communities as a whole, without prior knowledge of which organisms are in the environment or exactly how they are interacting. But sequence-based ecological studies nearly always use a comparative approach, and that requires relevant reference sequences, which are an ex- tremely limited resource when it comes to microbial eukaryotes [1]. [Read more

Published 24 June, 2014

Tags: PLOS Biology
Published May 31, 2015 8:15 AM - Last modified May 31, 2015 8:15 AM