Åsmund Kaupang

Postdoctoral Fellow
Image of Åsmund Kaupang
Norwegian version of this page
Phone +47-22856509
Room Ø177
Username
Visiting address Dept. of Physics Sem Sælands Vei 24
Postal address PO Box 1068 Blindern 0316 Oslo Norway

Academic Interests

Molecular modelling, structural biology, chemical biology, medicinal chemistry, synthetic organic chemistry, biochemistry, life science didactics.

Teaching

to be updated

Higher education and employment history

2017 - 2019

Researcher, Dept. of Chemistry / Computational Biology Unit (CBU), University of Bergen

2011 - 2016

Ph.D. in Medicinal Chemistry/Chemical Biology, School of Pharmacy, University of Oslo

2008 - 2010

M.Sc. in Chemistry (synthetic organic chemistry), Department of Chemistry, University of Oslo

 

Tags: Biochemistry, Chemistry, Pharmaceutical Chemistry, Life Science, Molecular modelling, Organic chemistry, Structural biology, Synthetic organic chemistry, Chemical biology, Chemical education

Publications

  • Kaupang, Åsmund & Hansen, Trond Vidar (2020). The PPAR Ω Pocket: Renewed Opportunities for Drug Development. PPAR Research.  ISSN 1687-4757.  2020 . doi: 10.1155/2020/9657380 Show summary
  • Kaupang, Åsmund; Laitinen, Tuomo; Poso, Antti & Hansen, Trond Vidar (2017). Structural review of PPARγ in complex with ligands: Cartesian- and dihedral angle principal component analyses of X-ray crystallographic data. Proteins: Structure, Function, and Bioinformatics.  ISSN 0887-3585.  85(9), s 1684- 1698 . doi: 10.1002/prot.25325 Full text in Research Archive.
  • Kaupang, Åsmund; Kase, Eili Tranheim; Vo, Cecilie Xuan Trang; Amundsen, Marthe; Vik, Anders & Hansen, Trond Vidar (2016). Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ. Bioorganic & Medicinal Chemistry.  ISSN 0968-0896.  24(2), s 247- 260 . doi: 10.1016/j.bmc.2015.12.012
  • Kaupang, Åsmund; Hildonen, Siri; Halvorsen, Trine Grønhaug; Mortén, Magnus; Vik, Anders & Hansen, Trond Vidar (2015). Involvement of covalent interactions in the mode of action of PPARβ/δ antagonists. RSC Advances.  ISSN 2046-2069.  5(93), s 76483- 76490 . doi: 10.1039/c5ra15707b
  • Kaupang, Åsmund; Paulsen, Steinar Martin; Steindal, Calin Constantin; Ravna, Aina Westrheim; Sylte, Ingebrigt; Halvorsen, Trine Grønhaug; Thoresen, G. Hege & Hansen, Trond Vidar (2015). Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. European Journal of Medicinal Chemistry.  ISSN 0223-5234.  94, s 229- 236 . doi: 10.1016/j.ejmech.2015.03.006 Full text in Research Archive.
  • Gorbitz, Carl Henrik; Bonge-Hansen, Tore & Kaupang, Åsmund (2013). N,N'-Bis(2-diazoacetyl)piperazine. Acta Crystallographica Section E: Structure Reports Online.  ISSN 1600-5368.  69(8), s o1241 . doi: 10.1107/S1600536813018801
  • Kaupang, Åsmund & Bonge-Hansen, Tore (2013). α-Bromodiazoacetamides – a new class of diazo compounds for catalyst-free, ambient temperature intramolecular C–H insertion reactions. Beilstein Journal of Organic Chemistry.  ISSN 2195-951X.  9, s 1407- 1413 . doi: 10.3762/bjoc.9.157
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Bonge-Hansen, Tore (2013). A solid-state oxidation of 1,1,3,3-tetramethylguanidinium 4-methylbenzenesulfinate to 1,1,3,3-tetramethylguanidinium 4-methylbenzenesulfonate. Acta Crystallographica Section C: Crystal Structure Communications.  ISSN 0108-2701.  69, s 778- + . doi: 10.1107/S0108270113015011
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Hansen, Tore (2011). 2-Diazo-1-(1,1-dioxothiomorpholin-4-yl)ethanone. Acta Crystallographica Section E: Structure Reports Online.  ISSN 1600-5368.  67, s O1844- U2037 . doi: 10.1107/S1600536811023774
  • Kaupang, Åsmund; Gorbitz, Carl Henrik & Hansen, Tore (2010). tert-Butyl 4-(2-diazoacetyl)piperazine-1-carboxylate. Acta Crystallographica Section E: Structure Reports Online.  ISSN 1600-5368.  66, s O2199- U467 . doi: 10.1107/S1600536810016211
  • Kaupang, Åsmund; Bolsones, M; Gamadeku, T; Hansen, Tore; Hennum, MJ & Gorbitz, Carl Henrik (2008). 2SR,3RS)-Benzyl[4-chloro-1-(4-chlorophenyl)-1-methoxycarbonyl-2-butyl]ammonium chloride. Acta Crystallographica Section E: Structure Reports Online.  ISSN 1600-5368.  64, s O2038- U4798 . doi: 10.1107/S1600536808030742

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  • Kaupang, Åsmund (2016). Development of PPAR Modulators and Investigations on their Mode of Action. Full text in Research Archive. Show summary
  • Kaupang, Åsmund; Hildonen, Siri; Halvorsen, Trine Grønhaug; Mortén, Magnus; Vik, Anders & Hansen, Trond Vidar (2015). Investigations on the covalent antagonistic modulation of PPARβ/δ.
  • Kaupang, Åsmund; Laitinen, Tuomo; Poso, Antti & Hansen, Trond Vidar (2013). Vibrational fingerprinting of hPPARγ in complex with ligands – application to the natural product (-)-mucosin.
  • Kaupang, Åsmund; Laitinen, Tuomo; Vik, Anders; Poso, Antti & Hansen, Trond Vidar (2013). Molecular modelling and synthesis of putative high-affinity inhibitors of hPPARδ.

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Published Sep. 24, 2019 3:01 PM - Last modified Apr. 29, 2020 1:11 PM