Åsmund Kaupang
Postdoctoral Fellow

Norwegian version of this page
Phone
+47-22856509
Room
Ø177
Username
Visiting address
Dept. of Physics
Sem Sælands Vei 24
Postal address
PO Box 1068 Blindern
0316 Oslo
Norway
Academic Interests
Computational biology, structural biology, chemical biology, medicinal chemistry, synthetic organic chemistry, biochemistry, life science didactics.
Teaching
Autumn 2021: FARM2100, FARM4120, FARM5000
Higher education and employment history
2017 - 2019
Researcher, Dept. of Chemistry / Computational Biology Unit (CBU), University of Bergen
2011 - 2016
Ph.D. in Medicinal Chemistry/Chemical Biology, School of Pharmacy, University of Oslo
2008 - 2010
M.Sc. in Chemistry (synthetic organic chemistry), Department of Chemistry, University of Oslo
Publications
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Primdahl, Karoline Gangestad; Kaupang, Åsmund; Park, Jong-Duk; Seyedsayamdost, Mohammad R.; Nolsøe, Jens M. J. & Aursnes, Marius (2022). On the Structure of Thailandene A: Synthetic Examination of the Cryptic Natural Product Aided by a Theoretical Approach. Synthesis (Stuttgart). ISSN 0039-7881. doi: 10.1055/s-0041-1737242.
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Kaupang, Åsmund & Hansen, Trond Vidar (2020). The PPAR Ω Pocket: Renewed Opportunities for Drug Development. PPAR Research. ISSN 1687-4757. 2020. doi: 10.1155/2020/9657380. Full text in Research Archive
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Kaupang, Åsmund; Laitinen, Tuomo; Poso, Antti & Hansen, Trond Vidar (2017). Structural review of PPARγ in complex with ligands: Cartesian- and dihedral angle principal component analyses of X-ray crystallographic data. Proteins: Structure, Function, and Bioinformatics. ISSN 0887-3585. 85(9), p. 1684–1698. doi: 10.1002/prot.25325. Full text in Research Archive
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Kaupang, Åsmund; Kase, Eili Tranheim; Vo, Cecilie Xuan Trang; Amundsen, Marthe; Vik, Anders & Hansen, Trond Vidar (2016). Synthesis of 5-trifluoromethyl-2-sulfonylpyridine PPARβ/δ antagonists: Effects on the affinity and selectivity towards PPARβ/δ. Bioorganic & Medicinal Chemistry. ISSN 0968-0896. 24(2), p. 247–260. doi: 10.1016/j.bmc.2015.12.012.
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Kaupang, Åsmund; Hildonen, Siri; Halvorsen, Trine Grønhaug; Mortén, Magnus; Vik, Anders & Hansen, Trond Vidar (2015). Involvement of covalent interactions in the mode of action of PPARβ/δ antagonists. RSC Advances. ISSN 2046-2069. 5(93), p. 76483–76490. doi: 10.1039/c5ra15707b.
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Kaupang, Åsmund; Paulsen, Steinar Martin; Steindal, Calin Constantin; Ravna, Aina Westrheim; Sylte, Ingebrigt & Halvorsen, Trine Grønhaug [Show all 8 contributors for this article] (2015). Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618. European Journal of Medicinal Chemistry. ISSN 0223-5234. 94, p. 229–236. doi: 10.1016/j.ejmech.2015.03.006. Full text in Research Archive
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Kaupang, Åsmund; Gorbitz, Carl Henrik & Bonge-Hansen, Tore (2013). N,N'-Bis(2-diazoacetyl)piperazine. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 69(8). doi: 10.1107/S1600536813018801.
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Kaupang, Åsmund; Gorbitz, Carl Henrik & Bonge-Hansen, Tore (2013). A solid-state oxidation of 1,1,3,3-tetramethylguanidinium 4-methylbenzenesulfinate to 1,1,3,3-tetramethylguanidinium 4-methylbenzenesulfonate. Acta Crystallographica Section C: Crystal Structure Communications. ISSN 0108-2701. 69, p. 778–+. doi: 10.1107/S0108270113015011.
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Kaupang, Åsmund & Bonge-Hansen, Tore (2013). α-Bromodiazoacetamides – a new class of diazo compounds for catalyst-free, ambient temperature intramolecular C–H insertion reactions. Beilstein Journal of Organic Chemistry. ISSN 2195-951X. 9, p. 1407–1413. doi: 10.3762/bjoc.9.157.
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Kaupang, Åsmund; Gorbitz, Carl Henrik & Hansen, Tore (2011). 2-Diazo-1-(1,1-dioxothiomorpholin-4-yl)ethanone. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 67, p. O1844–U2037. doi: 10.1107/S1600536811023774.
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Kaupang, Åsmund; Gorbitz, Carl Henrik & Hansen, Tore (2010). tert-Butyl 4-(2-diazoacetyl)piperazine-1-carboxylate. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 66, p. O2199–U467. doi: 10.1107/S1600536810016211.
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Kaupang, Åsmund; Bolsones, M; Gamadeku, T; Hansen, Tore; Hennum, MJ & Gorbitz, Carl Henrik (2008). 2SR,3RS)-Benzyl[4-chloro-1-(4-chlorophenyl)-1-methoxycarbonyl-2-butyl]ammonium chloride. Acta Crystallographica Section E: Structure Reports Online. ISSN 1600-5368. 64, p. O2038–U4798. doi: 10.1107/S1600536808030742.
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Kaupang, Åsmund; Hildonen, Siri; Halvorsen, Trine Grønhaug; Mortén, Magnus; Vik, Anders & Hansen, Trond Vidar (2015). Investigations on the covalent antagonistic modulation of PPARβ/δ.
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Kaupang, Åsmund; Laitinen, Tuomo; Vik, Anders; Poso, Antti & Hansen, Trond Vidar (2013). Molecular modelling and synthesis of putative high-affinity inhibitors of hPPARδ.
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Kaupang, Åsmund; Laitinen, Tuomo; Poso, Antti & Hansen, Trond Vidar (2013). Vibrational fingerprinting of hPPARγ in complex with ligands – application to the natural product (-)-mucosin.
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Kaupang, Åsmund (2016). Development of PPAR Modulators and Investigations on their Mode of Action. Faculty of Mathematics and Natural Sciences, University of Oslo. Full text in Research Archive Show summary
Published Sep. 24, 2019 3:01 PM
- Last modified Aug. 25, 2021 2:53 PM