Eric Ofosu Kissi

Image of Eric Ofosu Kissi
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Mobile phone +4792015729
Room 226
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Visiting address Sem Sælands vei 3 Farmasibygningen 0371 OSLO
Postal address Postboks 1068 Blindern 0316 OSLO
Other affiliations Department of Education (Student)

 

Presentation

3D printing is an additive manufacturing technique and materials are deposited layer by layer. This allows the design of solid dosage forms and personal medicines. The current 3D printing technique that we are using is fused deposition modelling (FDM) which is a thermodynamic pathway of producing amorphous and amorphous solid dispersion (ASD). We use hotmelt extrusion to prepare ASD filaments and print solid dosage forms using 3D printer. Currently, we are combining knowledge in amorphous pharmaceutics, formulation, solid-state characterisation and pharmaceutical technology to develop personalised medicines.


Research Interest

3D printing, personalised dosage form, amorphous pharmaceutics, poorly soluble drugs, terahertz spectroscopy, solid-state pharmaceutics, molecular mobility, thermal analysis


Background

Aug 2015-Sep 2018: PhD Pharmaceutical Sciences, University of Copenhagen, Copenhagen-Denmark

Sep 2012- June 2014: MSc Photonics (physics), University of Eastern Finland, Joensuu-Finland

Aug 2005- May 2009: BSc Chemistry, University of Cape Coast, Cape Coast-Ghana

June 2019: Guest researcher at Solid Solid State Pharmaceutics Group, University of Copenhagen, Copenhagen-Denmark

March 2019: Guest researcher at Chalmers University of Technology, Gothenburg-Sweden

Oct-Nov 2016: Guest researcher at Terahertz Application Group, University of Cambridge, Cambridge- UK


Publications

  1. Kissi, E. O.; Kasten G.; Löbmann, K.; Rades, T. and Grohganz, H. The Role of Glass Transition Temperatures in Co-Amorphous Drug-Amino Acid Formulations Mol. Pharmaceutics 2018, DOI:10.1021/acs.molpharmaceut.8b00650
  2. E. O. Kissi, H. Grohganz, K. Löbmann, M. T. Ruggiero, J. A. Zeitler, and T. Rades. Glass transition temperature of the β-relaxation as the major predictive parameter for recrystallization of neat amorphous drugs J Phy Chem B 2018. 122 (10), pp 2803–2808.
  3. M. T. Ruggiero, M. Krynski, E. O. Kissi, J. Sibik, D. Markl, N. Y. Tan, D. Arslanov, W. v. d. Zande, B. Redlich, T. M. Korter, H. Grohganz, K. Löbmann, T. Rades, S.R. Elliott, and J. A. Zeitler. The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallization. Phys. Chem. Chem. Phys. 2017, 19, 30039-30047.
  4. Eric Ofosu Kissi, Prince Bawuah, Pertti Silfsten, Kai-Erik Peiponen. A tape method for fast characterization and identification of active pharmaceutical ingredients in the 2-18 THz spectral range. J. Infrared Milli. Terahz. Wave March 2015, Volume 36, Issue 3, pp 278–290.

Google Scholar Publications

LinkedIn profile

Tags: 3D printing, personalised medicine, amorphous drug delivery, Hotmelt extrusion, Pharmaceutics, Pharmaceutical technology

Publications

  • Kissi, Eric Ofosu; Khorami, Keyoomars & Rades, Thomas (2019). Determination of Stable Co-Amorphous Drug–Drug Ratios from the Eutectic Behavior of Crystalline Physical Mixtures. Pharmaceutics.  ISSN 1999-4923.  11(12), s 1- 11 . doi: 10.3390/pharmaceutics11120628
  • Kissi, Eric Ofosu; Ruggiero, Michael T; Hempel, Nele-Johanna; Song, Zihui; Grohganz, Holger; Rades, Thomas & Lobmann, Korbinian (2019). Characterising glass transition temperatures and glass dynamics in mesoporous silica-based amorphous drugs. Physical Chemistry, Chemical Physics - PCCP.  ISSN 1463-9076.  21(35), s 19686- 19694 . doi: 10.1039/c9cp01764j
  • Lababidi, Nashrawan; Kissi, Eric Ofosu; Elgaher, Walid AM; Sigal, Valentin; Haupenthal, Jorg; Schwarz, Bianca C; Hirsch, Anna KH; Rades, Thomas & Schneider, Marc (2019). Spray-drying of inhalable, multifunctional formulations for the treatment of biofilms formed in cystic fibrosis. Journal of Controlled Release.  ISSN 0168-3659.  314, s 62- 71 . doi: 10.1016/j.jconrel.2019.10.038
  • Leng, Donglei; Kissi, Eric Ofosu; Lobmann, Korbinian; Thanki, Kaushik; Fattal, Elias; Rades, Thomas; Foged, Camilla & Yang, Mingshi (2019). Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy. AAPS PharmSciTech.  ISSN 1530-9932.  20(3) . doi: 10.1208/s12249-019-1344-9
Published Jan. 10, 2019 9:33 AM - Last modified Jan. 22, 2020 3:43 PM