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Guest lecture by professor Philippe Guérin, University of Oxford, UK.
Guest lecture by Caroline Maltepe, Hospital for Sick Children, Toronto.
The talk will focus on "Nanoparticle interaction with early human placenta", an upcoming topic in reproductive toxicology. Exposure to engineered nanomaterial is steadily increasing, but next to nothing is known about the interaction of nanomaterials with the maternal-embryonic interface in humans. This issue is especially challenging because the kinetics of nanomaterials is considered to be more dependent on the (highly species specific) histologic structure of the placental barrier than the kinetics of low molecular weight substances. This knowledge is important in order to address toxicological concerns but would also facilitate the future development of new therapeutic strategies for a target oriented treatment in pregnancy.