The NADESept products can be applied for disinfection (e.g. implants), or treatment of infections (e.g. wounds, oral infections) and can be classified as either medical- or drug products.
Spray formulations can be optimal for disinfection of surfaces such as implants or medical devices, or as sprayable wound dressings. For both applications, the spray will provide a large contact surface area of the formulation; and it will be easy and fast to administer even to poorly accessible areas of an implant or deep wound. The formulation will leave a protective, hydrophilic film on the contact surface. In case of wound infections, the film can be covered with a secondary bandage and will provide an optimal moist environment for wound healing to occur.
The major benefits of biocompatible sponges include their ability to absorb large quantities of tissue exudates, and their smooth adherence to moist wounds with preservation of the microclimate as well as shielding against secondary bacterial infections and mechanical harm. Porous sponges prepared from certain biomolecules can promote the activity of inflammatory cells and facilitate cellular growth. Such sponges can be considered as "active" dressings, which will benefit the wound healing process.
Tailoring of medicinal products and treatment to the individual characteristics of each patient improves the ability to detect, prevent and treat disease at an early stage. Technologies like 3D printing and electrospinning offer the possibility to tailor antimicrobial devices for a specific purpose or patient. The device, whether a printed unit or a polymeric nanofiber, can be functionalized with antimicrobial agents. These technologies are versatile to optimize the applicability and therapeutic abilities of antimicrobial products by adjusting e.g. product shape, size, pore structure, payload and release of antimicrobial agent.