Disputation: Krister Gjestvang Grønlien
Doctoral candidate Krister Gjestvang Grønlien at the Department of Pharmacy, Faculty of Mathematics and Natural Sciences, is defending the thesis "Sustainable use of rest raw materials: Properties of collagen from turkey (Meleagris gallopavo) and potential pharmaceutical and biomedical applications" for the degree of Philosophiae Doctor.
The PhD defence will be fully digital and streamed directly using Zoom. The host of the session will moderate the technicalities while the chair of the defence will moderate the disputation.
Ex auditorio questions: the chair of the defence will invite the audience to ask ex auditorio questions either written or oral. This can be requested by clicking 'Participants -> Raise hand'.
Title: Sustainable use of organic waste and byproducts in healthcare: what has been done and where are we heading?
Main research findings
The global demand and increase in consumption of meat products have led to the accumulation of large amounts of rest raw materials after the edible part is used. Rest raw materials such as skin, bones and tendons are often rich in fibrous proteins. Collagen is the major fibrous protein in both human and animal connective tissue, constituting about 20-30% of the total protein weight. In the present work, collagen was isolated from turkey (Meleagris gallopavo) rest raw materials and was characterized and utilized in development of products for pharmaceutical and biomedical applications. Previous research has revealed that collagen has properties that favor certain applications, including wound healing, tissue engineering and drug delivery. However, the physicochemical characteristics of collagen like slow gelation, and poor mechanical properties of the resulting products are challenging. The current work has applied natural solvents and nontoxic crosslinkers to achieve optimized products based on turkey collagen. Sponges, gels and sheets were prepared and characterized. The native antimicrobial properties of some of the preparations were increased in combination with light. The prototypes developed are promising and can contribute to a sustainable use of rest raw material from turkey.
- Medisinar med grøne råvarer kan lindra kroniske sår (Titan, June 2020 - in Norwegian)
- Restar av kalkun kan bli råstoff til medisin (Titan, June 2021 - in Norwegian)