Fatima Tauqeer

• Nasrin, Tania; Tauqeer, Fatima; Bjørndal, Ludvig Daae; Kittel-Schneider, Sarah & Lupattelli, Angela (2024). Partner support for women’s antidepressant treatment and its association with depressive symptoms in pregnant women, mothers, and women planning pregnancy. Archives of Women's Mental Health. ISSN 1434-1816. doi: 10.1007/s00737-024-01435-3.
• Tauqeer, Fatima; Moen, Anne; Myhr, Kirsten; Wilson, Claire A. & Lupattelli, Angela (2023). Assessing decisional conflict and challenges in decision-making among perinatal women using or considering using antidepressants during pregnancy—a mixed-methods study. Archives of Women's Mental Health. ISSN 1434-1816. 26, s. 669–683. doi: 10.1007/s00737-023-01341-0. Fulltekst i vitenarkiv Vis sammendrag

  This study aims to investigate decisional conflict and elucidate challenges in decision-making among perinatal women using or considering using antidepressant (AD) during pregnancy. A sequential, mixed-methods study was employed among pregnant and postnatal women in Norway who had been offered ADs in the last 5 years. Quantitative data were obtained through an electronic questionnaire. Decisional conflict in pregnancy was assessed using the Decisional Conflict Scale (DCS) defined as either low (

• Maisonneuve, Emeline; Gerbier, Eva; Tauqeer, Fatima; Pomar, Léo; Favre, Guillaume & Winterfeld, Ursula [Vis alle 12 forfattere av denne artikkelen] (2023). Determinants of Vaccination and Willingness to Vaccinate against COVID-19 among Pregnant and Postpartum Women during the Third Wave of the Pandemic: A European Multinational Cross-Sectional Survey. Viruses. ISSN 1999-4915. 15(5). doi: 10.3390/v15051090. Fulltekst i vitenarkiv
• Tauqeer, Fatima; Ceulemans, Michael; Gerbier, Eva; Passier, Anneke; Oliver, Alison & Foulon, Veerle [Vis alle 9 forfattere av denne artikkelen] (2023). Mental health of pregnant and postpartum women during the third wave of the COVID-19 pandemic: a European cross-sectional study. BMJ Open. ISSN 2044-6055. 13(1). doi: 10.1136/bmjopen-2022-063391. Fulltekst i vitenarkiv Vis sammendrag

  Objective: To describe the mental health of perinatal women in five European countries during the third pandemic wave and identify risk factors related to depressive and anxiety symptoms. Design: A cross-sectional, online survey-based study. Setting: Belgium, Norway, Switzerland, the Netherlands and the UK, 10 June 2021-22 August 2021. Participants: Pregnant and up to 3 months postpartum women, older than 18 years of age. Primary outcome measure: The Edinburgh Depression Scale (EDS) and the Generalised Anxiety Disorder scale (GAD-7) were used to assess mental health status. Univariate and multivariate generalised linear models were performed to identify factors associated with poor mental health. Results: 5210 women participated (including 3411 pregnant and 1799 postpartum women). The prevalence of major depressive symptoms (EDS ≥13) was 16.1% in the pregnancy group and 17.0% in the postpartum . Moderate to severe generalised anxiety symptoms (GAD ≥10) were found among 17.3% of the pregnant and 17.7% of the postpartum women. Risk factors associated with poor mental health included having a pre-existing mental illness, a chronic somatic illness, having had COVID-19 or its symptoms, smoking, unplanned pregnancy and country of residence. Among COVID-19 restrictive measures specific to perinatal care, pregnant and postpartum women were most anxious about not having their partner present at the time of delivery, that their partner had to leave the hospital early and to be separated from their newborn after the delivery. Conclusion: Approximately one in six pregnant or postpartum women reported major depression or anxiety symptoms during the third wave of the pandemic. These findings suggest a continued need to monitor depression and anxiety in pregnancy and postpartum populations throughout and in the wake of the pandemic. Tailored support and counseling are essential to reduce the burden of the pandemic on perinatal and infant mental health.

• Araya, Robin Aasegg; Tauqeer, Fatima; Ceulemans, Michael; Gerbier, Eva; Maisonneuve, Emeline & Passier, Anneke [Vis alle 10 forfattere av denne artikkelen] (2023). Pregnancy- and Birth-Related Experiences among Postpartum Women during the Third Wave of the COVID-19 Pandemic—A Multinational European Study. Pharmacoepidemiology. ISSN 2813-0618. 2(1), s. 54–67. doi: 10.3390/pharma2010006. Fulltekst i vitenarkiv Vis sammendrag

  The objective of this study was to describe pregnancy- and birth-related experiences of postpartum women during the third wave of the COVID-19 pandemic and their association with mental health outcomes. An online questionnaire was distributed in five European countries (Belgium, The Netherlands, Norway, Switzerland, UK) between June and August 2021. Participants were recruited though socialmedia platforms including pregnancy- and motherhood-related websites, pregnancy fora, and apps. Postpartum women were asked eleven specific questions about pregnancyand birth-related changes and the presence of support during delivery. The Edinburgh Depression Scale was used to assess depressive and anxiety symptoms. Covariates included sociodemographics, health and reproductive characteristics, and COVID-19 status. Associations were estimated with logistic regression. The study included 1730 postpartum women. Frequent changes included the exclusion of the partner from pregnancy care appointments (83.2%), changed prenatal care settings (64.4%), and cancellation of hospital information visits (42.7%). Few women, however, were without support apart from medical staff during delivery (1.4%). The number of pregnancy- and birth-related changes was associated with each woman’s mental health status, as well as the type of change. Experiencing changes related to delivery and cancellation or reduction of prenatal examination was associated with a doubling in the odds of symptoms of major depression and anxiety postpartum. These findings highlight the importance of ensuring adequate maternity care for women’s mental health postpartum, as well as during a pandemic.

• Batool, Narjis; Saleem, Zikria; Saeed, Hamid; Yasmeen, Sadia; Anwar, Rabia & Ahmad, Faheem [Vis alle 8 forfattere av denne artikkelen] (2022). Factors affecting health-related quality of life (HRQoL) in Pakistani children with thalassemia. Family Medicine and Primary Care Review. ISSN 1734-3402. 24(1), s. 37–42. doi: 10.5114/fmpcr.2022.113012. Vis sammendrag

  Background. Thalassemic patients have deteriorated quality of life, which affects their social status, leisure activities, ability to focus on task or series of task and relationships. Objectives. The objective of this study is to find factors associated with health-related quality of life (HRQoL) that either hinder or augment the effectiveness of therapy in thalassemia patients in Pakistan. Material and methods. A cross-sectional observational study was conducted among 178 children and adolescents with thalassemia in Lahore, Pakistan. The clinical characteristics of patients were recorded by checking medical records, and HRQoL was calculated using the PedsQL (Pediatric Quality of Life Inventory) scale. Results. The average of the total summary score of the study population was 63.91 (SD: 15.52). For the subscales of the PedsQL score, it was revealed that the social functioning score was 10.24 (SD: 5.55), school functioning score was 10.66 (SD: 4.75), emotional functioning score was 10.68 (SD: 3.78), physical functioning score was 14.84 (SD: 15.52) and general health functioning score was 17.49 (SD: 3.15). It was shown that age, rural residence, as well as serum ferritin, urea and AST levels, were significantly associated with HRQoL. White blood cell count, red blood cell count, platelet count and alanine transaminase were not significant predictors of HRQoL. Conclusions. Keeping in mind the current scenario in Pakistan, our study revealed that there is a need for improvement in thalassemia treatment management. For this, a modification of healthcare services can improve HRQoL, and thus improve the percentage of treatment outcomes in thalassemic patients.

• Bjørndal, Ludvig Daae; Tauqeer, Fatima; Heiervang, Kristin Sverdvik; Clausen, Hanne Kristin; Heitmann, Kristine & Lupattelli, Angela (2022). Perceived risk of neurodevelopmental outcomes in offspring related to psychotropic and mental illness exposures in pregnancy and breastfeeding: a cross-sectional survey of women with past or current mental illness. BMJ Open. ISSN 2044-6055. 12(9), s. 1–11. doi: 10.1136/bmjopen-2022-061159. Fulltekst i vitenarkiv Vis sammendrag

  Objectives: To investigate the perceived risk of psychotropic and mental illness exposures (1) during pregnancy or (2) while breastfeeding on offspring neurodevelopment, and factors associated with this perception in women with past/current mental illness. Design: Cross-sectional, web-based study. Setting: Nationwide in Norway, June 2020-June 2021. Participants: Women aged 18-55 years who were pregnant, recent mothers or planning a pregnancy, and had been offered antidepressants in the last 5 years. Primary and secondary outcome measures: Perceived risk of prenatal and breastmilk exposure to psychotropic medications and maternal mental illness on offspring neurodevelopmental outcomes. Results: We included 448 women: 234 pregnant, 146 mothers and 68 planning a pregnancy. On a 0-10 scale, women perceived antidepressants as least harmful both (1) in pregnancy (mean score 4.2, 95% CI 3.6 to 4.8) and (2) while breastfeeding (mean score 3.8, 95% CI 3.3 to 4.4), relative to antipsychotics, anxiety/sleeping medication or antiepileptics (mean score range: 6.3-6.5 during pregnancy, 5.5-6.2 while breastfeeding). Many participants were unfamiliar with psychotropics other than antidepressants. The perceived risk of mental illness exposure exceeded that of antidepressants (mean score range 5.6-5.9) in both exposure periods. Using general linear models, factors associated with greater antidepressant risk perception in both exposure periods included having lower education, non-Norwegian native language, and employment status (range mean score difference (β): 2.07-6.07). For pregnant women and mothers, there was an inverse association between perceived risk and the perceived antidepressant effectiveness in both exposure periods (range of β: -0.18 to -0.25). Conclusions: In women with past/current mental illness, the perceived risk of antidepressant exposure on child neurodevelopment was lower than that for maternal mental illness. Other psychotropic medications were perceived as more harmful. As medication risk perception influences the decision-making regarding treatment of mental illness, pre- and pregnancy counselling should target women with characteristics associated with higher perceived risk. Keywords: EPIDEMIOLOGY; MENTAL HEALTH; OBSTETRICS; PSYCHIATRY; THERAPEUTICS. © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

• Gerbier, Eva; Favre, Guillaume; Tauqeer, Fatima; Winterfeld, Ursula; Stojanov, Milos & Oliver, Alison [Vis alle 13 forfattere av denne artikkelen] (2022). Self-Reported Medication Use among Pregnant and Postpartum Women during the Third Wave of the COVID-19 Pandemic: A European Multinational Cross-Sectional Study. International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. 19(9), s. 1–16. doi: 10.3390/ijerph19095335. Fulltekst i vitenarkiv
• Tauqeer, Fatima; Wood, Mollie; Andersen, Sarah Hjorth; Lupattelli, Angela & Nordeng, Hedvig (2021). Perinatal use of triptans and other drugs for migraine - A nationwide drug utilization study. PLOS ONE. ISSN 1932-6203. 16(8). doi: 10.1371/journal.pone.0256214. Fulltekst i vitenarkiv Vis sammendrag

  Objective To characterize nationwide utilization patterns of migraine pharmacotherapy before, during, and after pregnancy in women with triptan use. Methods Population-based data were obtained by linking the Medical Birth Registry of Norway and the Norwegian Prescription Database from 2006 to 2017. We included 22,940 pregnancies among 19,669 women with at least one filled triptan prescription, a proxy for migraine, in the year before pregnancy or during pregnancy. The population was classified into four groups: i) continuers; ii) discontinuers; iii) initiators, and vi) post-partum re-initiators. Participant characteristics and prescription fills for other drugs such as analgesics, antinauseants, and preventive drugs among the groups were examined, along with an array of triptan utilization parameters. Results In total, 20.0% of the women were classified as triptan continuers, 54.1% as discontinuers, 8.0% as initiators, and 17.6% as re-initiators. Extended use of triptans (�15 daily drug doses/month) occurred among 6.9% of the continuers in the first trimester. The top 10% of triptan continuers and initiators accounted for 41% (95% CI: 39.2% - 42.5%) and 33% (95% CI: 30.3% - 35.8%) of the triptan volume, respectively. Triptan continuers and initiators had similar patterns of acute co-medication during pregnancy, but use of preventive drugs was more common among the continuers before, during, and after pregnancy. Conclusion Among women using triptans before and during pregnancy, one in four continued triptan treatment during pregnancy, and extended triptan use was relatively low. Triptan discontinuation during and in the year after pregnancy was common. Use of other acute migraine treatments was higher among both continuers and initiators of triptans. Women using preventive migraine treatment were most commonly triptan continuers and re-initiators after pregnancy. Prescribing to and counseling of women with migraine should be tailored to the condition severity and their information needs to promote optimal migraine management in pregnancy. Introduction

• Dudman, Daniel C.; Tauqeer, Fatima; Kaur, Moninder; Ritchey, Mary E.; Li, Hu & Lopez-Leon, Sandra (2021). A systematic review and meta-analyses on the prevalence of pregnancy outcomes in migraine treated patients: a contribution from the IMI2 ConcePTION project. Journal of Neurology. ISSN 0340-5354. 269, s. 742–749. doi: 10.1007/s00415-021-10534-5.
• Umair, Muhammad; Ahmad, Mobasher; Saeed, Hamid; Saleem, Zikria & Tauqeer, Fatima (2020). Clinical efficacy of various anti-hypertensive regimens in hypertensive women of Punjab; A longitudinal cohort study. BMC Women's Health. ISSN 1472-6874. 20(1). doi: 10.1186/s12905-020-01033-2.
• Andersen, Sarah Hjorth; Wood, Mollie; Tauqeer, Fatima & Nordeng, Hedvig Marie Egeland (2020). Fertility treatment and oral contraceptive discontinuation for identification of pregnancy planning in routinely collected health data – an application to analgesic and antibiotic utilisation. BMC Pregnancy and Childbirth. ISSN 1471-2393. 20. doi: 10.1186/s12884-020-03435-4. Fulltekst i vitenarkiv
• Tauqeer, Fatima; Myhr, Kirsten & Gopinathan, Unni (2019). Institutional barriers and enablers to implementing and complying with internationally accepted quality standards in the local pharmaceutical industry of Pakistan: a qualitative study. Health Policy and Planning. ISSN 0268-1080. 34(6), s. 440–449. doi: 10.1093/heapol/czz054. Fulltekst i vitenarkiv Vis sammendrag

  Complying with good manufacturing practices (GMP) and ensuring a quality system is integral to production and supply of quality medicines and achieving universal health coverage. This study focus on the local production of medicines in Pakistan, a lower middle-income country that has observed considerable growth in the number of pharmaceutical companies over the past two decades. Against this background, we investigated: (1) How is quality assurance (QA) and GMP compliance understood and acted upon by local pharmaceutical manufacturers?; (2) What are the institutional barriers and enablers for QA and GMP compliance in the local pharmaceutical sector from the perspective of key stakeholders?; and (3) What are the institutional barriers and enablers for strengthening local regulatory capacity to improve QA in the industry in the long term? We used a qualitative study design involving 22 interviews of the drug regulatory bodies (n = 9), academia (n = 3) and local manufacturers (n = 10), identifying key themes in data by thematic analysis. Document analysis was used to collect additional information and supplement the interview data. We identified that manufacturing facilities operated under different GMP standards and interpretations, pointing towards an absence of harmonization in quality standards across the industry. Views diverged about the status of GMP compliance, with interviewees from academia presenting a more critical view compared with regulators who promoted a more positive story. Among the barriers explaining why companies struggled with quality standards, the lack of a mindset promoting quality and safety among profit-oriented manufacturers was prominent. At the federal level, DRAP’s establishment represented an institutional improvement aiming to promote QA through inspections and guidance. While some positive measures to promote quality have been observed, the need for DRAP to strengthen its technical and regulatory capacity, enhance its engagement in international collaboration and learning, and improve transparency and accountability were highlighted. Overall, since the challenges in Pakistan are shared with other low- and middle-income countries with local production, there is a need to commit to international collaborative mechanisms, such as those lead by WHO, on this issue.

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