Hanne Hjorth Tønnesen

Professor - Seksjon for farmasi
Bilde av Hanne Hjorth Tønnesen
English version of this page
Telefon +47-22856593
Rom 187
Brukernavn
Besøksadresse Sem Sælands vei 3 Farmasibygningen 0371 OSLO
Postadresse Postboks 1068 Blindern 0316 OSLO

Faglige interesser

  • Fotoreaktivitet av legemidler
  • Formulering av legemidler med dårlig "drugability", herunder biomolekyler
  • Bruk av Natural Deep Eutectic Solvents (NADES) i aPDT
  • Formulering av legemidler til bruk i (antibakteriell) fotodynamisk terapi basert på nanopartikler
  • Stabilitet (primært fotostabilitet) av legemider og formuleringer
  • Standardisering av fotokjemisk stabilitetstesting
  • Farmasihistorie

Undervisning

Bakgrunn

Professor i galenisk farmasi

Dr.scient i galenisk farmasi

 

Se engelsk versjon av personprofil.

 

Emneord: Legemiddelteknologi, Legemiddelstabilitet, Lysstabilitet, Fotodynamisk terapi, Nanoteknologi, Life science, Farmasi, Legemiddelformulering, Legemidler

Publikasjoner

  • Tovsen, Marianne Lilletvedt; Tho, Ingunn & Tønnesen, Hanne Hjorth (2018). Viscosity reduction of isotonic solutions of the photosensitizer TPCS2a by cyclodextrin complexation. Drug Development and Industrial Pharmacy.  ISSN 0363-9045.  44(2), s 261- 265 . doi: 10.1080/03639045.2017.1386210
  • Bergh, Victoria Jeaninne Valeron & Tønnesen, Hanne Hjorth (2017). Interaction between the photosensitizer lumichrome and human serum albumin: effect of excipients. Pharmaceutical development and technology (Print).  ISSN 1083-7450.  22(8), s 992- 1000 . doi: 10.1080/10837450.2016.1212883
  • Bergh, Victoria Jeaninne Valeron & Tønnesen, Hanne Hjorth (2017). Interactions and solubilization of 5, 10, 15, 20-tetrakis(4-hydroxyphenyl)porphyrin with poloxamer 407 and β-cyclodextrin-derivatives in binary and ternary systems. Journal of Drug Delivery Science and Technology.  ISSN 1773-2247.  37, s 51- 60 . doi: 10.1016/j.jddst.2016.11.004
  • Wikene, Kristine Opsvik; Rukke, Håkon Valen; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2017). Investigation of the antimicrobial effect of natural deep eutectic solvents (NADES) as solvents in antimicrobial photodynamic therapy. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  171, s 27- 33 . doi: 10.1016/j.jphotobiol.2017.04.030 Vis sammendrag
  • Allain, Leonardo; Baertschi, Steven W.; Clapham, David; Foti, Chris; Lantaff, Wendy M.; Reed, Robert A.; Templeton, Allen C. & Tønnesen, Hanne Hjorth (2016). Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 3. Oral Drug Products. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  105(5), s 1586- 1594 . doi: 10.1016/j.xphs.2016.02.035
  • Bergh, Victoria Jeaninne Valeron & Tønnesen, Hanne Hjorth (2016). Interaction between the photosensitizer lumichrome and human serum albumin:effect of excipients. Pharmaceutical development and technology (Print).  ISSN 1083-7450. . doi: 10.1080/10837450.2016.1212883
  • Vukicevic, Milica & Tønnesen, Hanne Hjorth (2016). Interaction between curcumin and human serum albumin in the presence of excipients and the effect of binding on curcumin photostability. Pharmaceutical development and technology (Print).  ISSN 1083-7450.  21(4), s 428- 436 . doi: 10.3109/10837450.2015.1016618
  • Wikene, Kristine Opsvik; Rukke, Håkon Valen; Bruzell, Ellen Merete & Tønnesen, Hanne Hjorth (2016). Physicochemical characterisation and antimicrobial phototoxicity of an anionic porphyrin in natural deep eutectic solvents. European journal of pharmaceutics and biopharmaceutics.  ISSN 0939-6411.  105, s 75- 84 . doi: 10.1016/j.ejpb.2016.06.001 Vis sammendrag
  • Baertschi, Steven W.; Clapham, David; Foti, Chris; Kleinman, Mark H.; Kristensen, Solveig; Reed, Robert A.; Templeton, Allen C. & Tønnesen, Hanne Hjorth (2015). Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 2: Topical Drug Product. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  104(9), s 2688- 2701 . doi: 10.1002/jps.24396
  • Benediktsdóttir, Berglind Eva; Baldursson, Ólafur; Gudjónsson, Thorarinn; Tønnesen, Hanne Hjorth & Masson, Már (2015). Curcumin, bisdemethoxycurcumin and dimethoxycurcumin complexed with cyclodextrins have structure specific effect on the paracellular integrity of lung epithelia in vitro. Biochemistry and Biophysics Reports.  ISSN 2405-5808.  4, s 405- 410 . doi: 10.1016/j.bbrep.2015.11.004
  • Bergh, Victoria Jeaninne Valeron; Bruzell, Ellen Merete; Hegge, Anne Bee & Tønnesen, Hanne Hjorth (2015). Influence of formulation on photoinactivation of bacteria by lumichrome. Pharmazie.  ISSN 0031-7144.  70(9), s 574- 580 . doi: 10.1691/ph.2015.5006
  • Larsen, Benjamin Endré; Bjørnstad, Jorunn; Pettersen, Erik O; Tønnesen, Hanne Hjorth & Melvik, Jan Egil (2015). Rheological characterization of an injectable alginate gel system. BMC Biotechnology.  ISSN 1472-6750.  15:29 . doi: 10.1186/s12896-015-0147-7
  • Larsen, Benjamin Endré; Pettersen, Erik O; Tønnesen, Hanne Hjorth & Melvik, Jan Egil (2015). Microenvironment-dependent respiration of T-47D cells cultured in alginate biostructures. Cell Proliferation.  ISSN 0960-7722.  48(3), s 318- 329 . doi: 10.1111/cpr.12178 Vis sammendrag
  • Tovsen, Marianne Lilletvedt; Smistad, Gro; Bjerke, Trude Marie; Tønnesen, Hanne Hjorth & Kristensen, Solveig (2015). Physicochemical Stability of Emulsions and Admixtures for Parenteral Nutrition during Irradiation by Glass-Filtered Daylight at Standardized Conditions. PDA journal of pharmaceutical science and technology.  ISSN 1079-7440.  69, s 346- 354 . doi: 10.5731/pdajpst.2015.01036
  • Vukicevic, Milica; Hegge, Anne Bee; Vulic, Predrag & Tønnesen, Hanne Hjorth (2015). Poloxamer-based curcumin solid dispersions for ex tempore preparation of supersaturated solutions intended for antimicrobial photodynamic therapy. Pharmaceutical development and technology (Print).  ISSN 1083-7450.  20(7), s 863- 871 . doi: 10.3109/10837450.2014.930489
  • Wikene, Kristine Opsvik; Bruzell, Ellen Merete & Tønnesen, Hanne Hjorth (2015). Characterization and antimicrobial phototoxicity of curcumin dissolved in natural deep eutectic solvents. European Journal of Pharmaceutical Sciences.  ISSN 0928-0987.  80, s 26- 32 . doi: 10.1016/j.ejps.2015.09.013
  • Wikene, Kristine Opsvik; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2015). Improved antibacterial phototoxicity of a neutral porphyrin in natural deep eutectic solvents. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  148, s 188- 196 . doi: 10.1016/j.jphotobiol.2015.04.022
  • Wikene, Kristine Opsvik; Hegge, Anne Bee; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2015). Formulation and characterization of lyophilized curcumin solid dispersions for antimicrobial photodynamic therapy (aPDT): studies on curcumin and curcuminoids LII. Drug Development and Industrial Pharmacy.  ISSN 0363-9045.  41(6), s 969- 977 . doi: 10.3109/03639045.2014.919315
  • Lamperti, Marco; Maspero, Angelo; Tønnesen, Hanne Hjorth; Bondani, Maria & Nardo, Luca (2014). Elucidation of the relationships between H-bonding patterns and excited state dynamics in cyclovalone. Molecules.  ISSN 1420-3049.  19(9), s 13282- 13304 . doi: 10.3390/molecules190913282
  • Tovsen, Marianne Lilletvedt; Bruzell, Ellen; Ferrari, Erika; Saladini, Monica; Gaware, Vivek S.; Másson, Már; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2014). Antibacterial phototoxic effects of synthetic asymmetric and glycosylated curcuminoids in aqueous formulations: Studies on curcumin and curcuminoids. LIV. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  140, s 150- 156 . doi: 10.1016/j.jphotobiol.2014.07.013
  • Vukicevic, Milica; Randeberg, Lise Lyngsnes; Boschker, Jos Emiel; Tybell, Thomas & Tønnesen, Hanne Hjorth (2014). Influence of crystal modification on the photoinduced color change in riboflavin. Pharmazie.  ISSN 0031-7144.  69(2), s 117- 124 . doi: 10.1691/ph.2014.3064
  • Baertschi, Steven W; Clapham, David; Foti, Chris; Jansen, Patrick; Kristensen, Solveig; Reed, Robert A.; Templeton, Allen & Tønnesen, Hanne Hjorth (2013). Implications of in -use photostability: proposed guidance for photostability testing and labeling to support the administration of photosensitive pharmaceutical products, part 1: drug products administered by injection. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  102(11), s 3888- 3899 . doi: 10.1002/jps.23717
  • Hegge, Anne Bee; Mysterud, Ivar; Karlsen, Jan; Skulberg, Olav Magnus; Laane, Carl Morten Motzfeldt; Schumacher, Trond & Tønnesen, Hanne Hjorth (2013). Impaired secondary oxidant deactivation capacity and enhanced oxidative stress in serum from alveld affected lambs. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  126, s 126- 134 . doi: 10.1016/j.jphotobiol.2013.07.005
  • Hegge, Anne Bee; Vukicevic, Milica; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2013). Solid dispersions for preparation of phototoxic supersaturated solutions for antimicrobial photodynamic therapy (aPDT) Studies on curcumin and curcuminoides L. European journal of pharmaceutics and biopharmaceutics.  ISSN 0939-6411.  83(1), s 95- 105 . doi: 10.1016/j.ejpb.2012.09.011 Vis sammendrag
  • Singh, Ravinder; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2013). Influence of vehicle properties and excipients on hydrolytic and photochemical stability of curcumin in preparations containing Pluronics. Pharmazie.  ISSN 0031-7144.  68, s 160- 169
  • Singh, Ravinder; Tønnesen, Hanne Hjorth; Kristensen, Solveig & Berg, Kristian (2013). The influence of Pluronics (R) on dark cytotoxicity, photocytotoxicity, localization and uptake of curcumin in cancer cells: studies of curcumin and curcuminoids XLIX. Photochemical and Photobiological Sciences.  ISSN 1474-905X.  12(3), s 559- 575 . doi: 10.1039/c2pp25249j
  • Sobczynski, Jan; Tønnesen, Hanne Hjorth & Kristensen, Solveig (2013). Influence of aqueous media properties on aggregation and solubility of four structurally related meso-porphyrin photosensitizers evaluated by spectrophotometric measurements. Pharmazie.  ISSN 0031-7144.  68, s 100- 109 . doi: 10.1691/ph.2013.2130
  • Tønnesen, Hanne Hjorth; Mysterud, Ivar; Karlsen, Jan; Skulberg, Olav Magnus; Laane, Carl Morten Motzfeldt & Schumacher, Trond (2013). Identification of singlet oxygen photosensitizes in lambs drinking water in an alveld risk area in West Norway. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  119, s 37- 45 . doi: 10.1016/j.jphotobiol.2012.12.003 Vis sammendrag
  • Hegge, Anne Bee; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2012). Photoinactivation of Stahpylococcus epidermidis biofilms and suspensions by the hydrophobic photosensitizer curcumin- effect of selected nanocarrierStudies of curcumin and curcuminoides XLVII. European Journal of Pharmaceutical Sciences.  ISSN 0928-0987.  47(1), s 65- 74 . doi: 10.1016/j.ejps.2012.05.002
  • Hegge, Anne Bee; Terndrup Nielsen, Thorbjørn; Lambertsen Larsen, Kim; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2012). Impact of curcumin supersaturation in antibacterial photodynamic therapy - Effect of cyclodextrin type and amount: Studies on curcumin and curcuminoides XLV. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  101(4), s 1524- 1537 . doi: 10.1002/jps.23046
  • Nardo, Luca; Andreoni, Alessandra; Bondani, Maria; Másson, Már; Haukvik, Tone & Tønnesen, Hanne Hjorth (2012). Studies on Curcumin and Curcuminoids. XLVI. Photophysical Properties of Dimethoxycurcumin and Bis-dehydroxycurcumin. Journal of Fluorescence.  ISSN 1053-0509.  22(2), s 597- 608 . doi: 10.1007/s10895-011-0995-z
  • Nardo, Luca; Bondani, Maria & Tønnesen, Hanne Hjorth (2012). Elucidating the relationship between the phenolic substituents and the excited state dynamics of curcuminoids, In Jun Sasaki & Masaki Kichida (ed.),  Curcumin. Biosynthesis, medicinal uses and health benefits.  Nova Science Publishers, Inc..  ISBN 978-1-61942-481-4.  Chapter III.  s 81 - 105
  • Nardo, Luca; Kristensen, Solveig; Tønnesen, Hanne Hjorth; Høgset, Anders & Lilletvedt, Marianne (2012). Solubilization of the photosensitizers TPCS2a and TPPS2a in aqueous media evaluated by time-resolved fluorescence analysis. Pharmazie.  ISSN 0031-7144.  67(7), s 598- 600 . doi: 10.1691/ph.2012.1791
  • Singh, Ravinder; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2012). Influence of cosolvents, ionic strength and the method of sample preparation on the solubilization of curcumin by Pluronics and HP-γ-cyclodextrin Studies of curcumin and curcuminoids, XLIV. Pharmazie.  ISSN 0031-7144.  67(2), s 131- 142 . doi: 10.1691/ph.2012.1097
  • Singh, Ravinder; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2012). Influence of vehicle properties and excipients on hydrolytic and photochemical stability of curcumin in preparations containing Pluronics. Studies on curcumin and curcuminoids XLVIII. Pharmazie.  ISSN 0031-7144.  67(11), s 1- 10
  • Haukvik, Tone; Bruzell, E; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2011). A screening of curcumin derivatives for antibacterial phototoxic effects Studies on curcumin and curcuminoids. XLIII. Pharmazie.  ISSN 0031-7144.  66(1), s 69- 74 . doi: 10.1691/ph.2011.0154
  • Hegge, Anne Bee; Andersen, Therese; Melvik, J.E.; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2011). Formulation and Bacterial Phototoxicity of Curcumin Loaded Alginate Foams for Wound Treatment Applications: Studies on Curcumin and Curcuminoides XLII. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  100(1), s 174- 185 . doi: 10.1002/jps.22263
  • Lilletvedt, Marianne; Smistad, Gro; Tønnesen, Hanne Hjorth; Høgset, Anders & Kristensen, Solveig (2011). Solubilization of the novel anionic amphiphilic photosensitizer TPCS2a by nonionic Pluronic block copolymers. European Journal of Pharmaceutical Sciences.  ISSN 0928-0987.  43(3), s 180- 187 . doi: 10.1016/j.ejps.2011.04.004
  • Lilletvedt, Marianne; Tønnesen, Hanne Hjorth; Høgset, Anders; Sande, Sverre Arne & Kristensen, Solveig (2011). Evaluation of physicochemical properties and aggregation of the photosensitizers TPCS2a and TPPS2a in aqueous media. Pharmazie.  ISSN 0031-7144.  66(5), s 325- 333 . doi: 10.1691/ph.2011.0337
  • Nardo, Luca; Andreoni, Alessandra; Masson, Már; Haukvik, Tone & Tønnesen, Hanne Hjorth (2011). Studies on Curcumin and Curcuminoids. XXXIX. Photophysical Properties of Bisdemethoxycurcumin. Journal of Fluorescence.  ISSN 1053-0509.  21(2), s 627- 635 . doi: 10.1007/s10895-010-0750-x
  • Christensen, Terje; Morisbak, Else; Tønnesen, Hanne Hjorth & Bruzell, Ellen (2010). In vitro photosensitization initiated by camphorquinone and phenyl propanedione in dental polymeric materials. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  100(3), s 128- 134 . doi: 10.1016/j.jphotobiol.2010.05.012
  • Haukvik, Tone; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2010). Photokilling of bacteria by curcumin in selected polyethylene glycol 400 (PEG 400) preparations Studies on curcumin and curcuminoids, XLI. Pharmazie.  ISSN 0031-7144.  65(8), s 600- 606 . doi: 10.1691/ph.2010.0048
  • Hegge, Anne Bee; Andersen, T; Melvik, Jan Egil; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2010). Phototoxicity of curcumin loaded alginate foams to Enterococcus faecalis and Escherichia coil in vitro. Journal of Pharmacy and Pharmacology (JPP).  ISSN 0022-3573.  62(10), s 1458- 1459
  • Hegge, Anne Bee; Andersen, T; Melvik, Jan Egil; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2010). Evaluation of Novel Alginate Foams as Drug Delivery Systems in Antimicrobial Photodynamic Therapy (aPDT) of Infected Wounds An In Vitro Study: Studies on Curcumin and Curcuminoides XL. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  99(8), s 3499- 3513 . doi: 10.1002/jps.22119
  • Lilletvedt, Marianne; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2010). Lumichrome complexation by cyclodextrins: Influence of pharmaceutical excipients. Pharmazie.  ISSN 0031-7144.  65(12), s 871- 876 . doi: 10.1691/ph.2010.0680
  • Lilletvedt, Marianne; Kristensen, Solveig; Tønnesen, Hanne Hjorth; Høgset, Anders & Nardo, Luca (2010). Time-domain evaluation of drug-solvent interactions of the photosensitizers TPCS2a and TPPS2a as part of physicochemical characterization. Journal of Photochemistry and Photobiology A: Chemistry.  ISSN 1010-6030.  214(1), s 40- 47 . doi: 10.1016/j.jphotochem.2010.06.004
  • Lilletvedt, Marianne; Tønnesen, Hanne Hjorth; Høgset, Anders; Nardo, Luca & Kristensen, Solveig (2010). Physicochemical characterization of the photosensitizers TPCS2a and TPPS2a 1. Spectroscopic evaluation of drug - solvent interactions. Pharmazie.  ISSN 0031-7144.  65(8), s 588- 595 . doi: 10.1691/ph.2010.0025
  • Singh, Ravinder; Tønnesen, Hanne Hjorth; Vogensen, Stine Byskov; Loftsson, Thorsteinn & Másson, Már (2010). Studies of curcumin and curcuminoids. XXXVI. The stoichiometry and complexation constants of cyclodextrin complexes as determined by the phase-solubility method and UV-Vis titration. Journal of inclusion phenomena and molecular recognition in chemistry.  ISSN 0923-0750.  66(3-4), s 335- 348 . doi: 10.1007/s10847-009-9651-5
  • Tønnesen, Hanne Hjorth; Mysterud, Ivar; Karlsen, Jan; Skulberg, Olav Magnus; Laane, Carl Morten Motzfeldt & Schumacher, Trond (2010). Detection of singlet oxygen in blood serum samples of clinically healthy lambs and lambs suffering from alveld disease. Veterinary research communications.  ISSN 0165-7380.  34(4), s 347- 357 . doi: 10.1007/s11259-010-9362-9
  • Haukvik, Tone; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Photokilling of bacteria by curcumin in different aqueous preparations. Studies on curcumin and curcuminoids XXXVII. Pharmazie.  ISSN 0031-7144.  64(10), s 666- 673 . doi: 10.1691/ph.2009.9130
  • Hegge, Anne Bee; Másson, Már; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Investigation of curcumin-cyclodextrin inclusion complexation in aqueous solutions containing various alcoholic co-solvents and alginates using an UV-VIS titration method. Pharmazie.  ISSN 0031-7144.  64(6), s 382- 389 . doi: 10.1691/ph.2009.8380
  • Kristensen, Solveig; Edge, Ruth; Tønnesen, Hanne Hjorth; Bisby, Roger H. & Navaratnam, Suppiah (2009). Photoreactivity of biologically active compounds. XIX: Excited states and free radicals from the antimalarial drug primaquine. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  94(3), s 147- 157 . doi: 10.1016/j.jphotobiol.2008.11.006
  • Nardo, Luca; Andreoni, Alessandra; Bondani, Maria; Másson, Már & Tønnesen, Hanne Hjorth (2009). Studies on curcumin and curcuminoids. XXXIV. Photophysical properties of a symmetrical, non-substituted curcumin analogue. Journal of Photochemistry and Photobiology. B: Biology.  ISSN 1011-1344.  97(2), s 77- 86 . doi: 10.1016/j.jphotobiol.2009.08.004
  • Singh, Ravinder; Tønnesen, Hanne Hjorth; Vogensen, Stine Byskov; Loftsson, Thorsteinn & Másson, Már (2009). Studies of curcumin and curcuminoids. XXXVI. The stoichiometry and complexation constants of cyclodextrin complexes as determined by the phase-solubility method and UV-Vis titration. Journal of inclusion phenomena and molecular recognition in chemistry.  ISSN 0923-0750. . doi: 10.1007/s10847-009-9651-5

Se alle arbeider i Cristin

  • Alopaeus, Julia Fredrika; Nguyen, Lina Mai; Pohjavirta, Jennie; Hagesæther, Ellen; Tønnesen, Hanne Hjorth & Tho, Ingunn (2018). Evaluation of concentration-dependent self-assembling structures of Soluplus and their properties in oral drug delivery.
  • Grønlien, Krister Gjestvang & Tønnesen, Hanne Hjorth (2018). Characterization of collagen from turkey for application in pharmaceutical preparations.
  • Ovchinnikov, Kirill; Reinseth, Ingvild; Tønnesen, Hanne Hjorth; Carlsen, Harald & Diep, Dzung B. (2018). The leaderless bacteriocin enterocin K1 is highly potent against Enterococcus faecium: a study on structure, receptor and pre-formulation..
  • Bruzell, Ellen Merete; Wikene, Kristine Opsvik; Rukke, Håkon Valen & Tønnesen, Hanne Hjorth (2017). Pharmaceutical formulation as a measure to improve antimicrobial phototoxicity.
  • Sørheim, Kristin; Brunberg, Emma; Grøva, Lise; Lande, Unni Støbet; Tovsen, Marianne Lilletvedt; Grønlien, Krister Gjestvang; Tønnesen, Hanne Hjorth; Karlsen, Jan; Skulberg, Olav & Mysterud, Ivar (2016). Alveld hos lam - kan vi forebygge sykdommen?.
  • Alopaeus, Julia Fredrika; Tønnesen, Hanne Hjorth & Tho, Ingunn (2015). The influence of drug-cyclodextrin inclusion complexes on properties of hydroxypropyl cellulose based orodispersible films.
  • Tønnesen, Hanne Hjorth & Wikene, Kristine Opsvik (2015). Eutectic solvents and uses thereof.
  • Tønnesen, Hanne Hjorth & Karlsen, Jan (2014). Legemiddelformulering - allemannseie eller fagspesialitet?. Kjemi.  ISSN 0023-1983.  74(5), s 26- 30
  • Wikene, Kristine Opsvik; Hegge, Anne Bee; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2014). Formulation and characterisation of lyophilised curcumin solid dispersions for antimicrobial photodynamic therapy (aPDT).
  • Wikene, Kristine Opsvik; Rukke, Håkon Valen; Tønnesen, Hanne Hjorth & Bruzell, Ellen (2014). Antimicrobial photodynamic therapy does not induce OxyR and SoxS antioxidant defence systems in Escherichia coli.
  • Bruzell, Ellen; Hegge, Anne Bee & Tønnesen, Hanne Hjorth (2013). Antimicrobial photodynamic treatment of oral infections.
  • Hegge, Anne Bee; Vukicevic, Milica; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2013). Supersaturation and supersaturated drug delivery systems to surpass the outer membrane barriers of gram negative bacteria in antimicrobial photodynamic therapy (aPDT).
  • Sobczynski, Jan; Kristensen, Solveig; Smistad, Gro; Hegge, Anne Bee; Tønnesen, Hanne Hjorth & Berg, Alf Kristian (2013). The influence of Pluronic block copolymers on solubilization and photocytotoxicity of porphyrin photosensitizers.
  • Tønnesen, Hanne Hjorth; Hegge, Anne Bee & Bruzell, Ellen (2013). Application of nanovehicles in preparations for antimicrobial photodynamic therapy (aPDT).
  • Vukicevic, Milica; Hegge, Anne Bee & Tønnesen, Hanne Hjorth (2013). Ex tempore prepared supersaturated solutions of curcumin intended for aPDT.
  • Vukicevic, Milica; Hegge, Anne Bee & Tønnesen, Hanne Hjorth (2013). Formulation and characterization of solid dispersions of a model photosensitizer.
  • Vukicevic, Milica; Hegge, Anne Bee; Tønnesen, Hanne Hjorth & Bruzell, Ellen (2013). Ex tempore prepered superstaurated solutions of curcumin intended for aPDT.
  • Haukvik, Tone; Tønnesen, Hanne Hjorth; Kristensen, Solveig; Dahl, Jon Einar & Bruzell, Ellen (2012). Curcumin as a photosensitizer in antibacterial photodynamic therapy. Influence of formulation and molecular structure modifications.
  • Hegge, Anne Bee; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2012). Photoinactivation of bacterial biofilms and supensions by cyclodextrin complexes of curcumin.
  • Kristensen, Solveig; Lilletvedt, Marianne; Sobczyński, Jan; Smistad, Gro; Nardo, Luca; Høgset, Anders & Tønnesen, Hanne Hjorth (2012). Solubilization of porphyrin photosensitizers by nonionic Pluronic block copolymers.
  • Kristensen, Solveig; Lilletvedt, Marianne; Sobczyński, Jan; Tønnesen, Hanne Hjorth; Smistad, Gro; Nardo, Luca & Høgset, Anders (2012). INCORPORATION OF PORPHYRIN PHOTOSENSITIZERS INTO NONIONIC PLURONIC BLOCK COPOLYMERIC NANOCARRIERS.
  • Lilletvedt, Marianne; Tønnesen, Hanne Hjorth; Smistad, Gro; Nardo, Luca; Høgset, Anders & Kristensen, Solveig (2012). Pharmaceutical preformulation of a novel photosensitizer for use in the technology of photochemical internalization (PCI).
  • Skulberg, Olav Magnus; Mysterud, Ivar; Karlsen, Jan; Tønnesen, Hanne Hjorth; Laane, Carl Morten Motzfeldt & Schumacher, Trond (2012). Søkelys på cyanobakterier vi vet lite om. Biolog.  ISSN 0801-0722.  30(3), s 32- 41
  • Vukicevic, Milica; Hegge, Anne Bee; Tuveng, Tina Rise; Tønnesen, Hanne Hjorth & Kristensen, Solveig (2012). Solid state characterization of dispersions of the poorly soluble photosensitizer curcumin.
  • Hegge, Anne Bee; Bruzell, Ellen & Tønnesen, Hanne Hjorth (2011). Curcumin phototoxicity on gram negative bacteria using selected cyclodextrins - Impact of supersaturation on antibacterial photodynamic therapy (aPDT).
  • Lilletvedt, Marianne; Tønnesen, Hanne Hjorth; Høgset, Anders; Smistad, Gro & Kristensen, Solveig (2011). Pharmaceutical preformulation of the novel photosensitizer TPCS2a for use in photochemical internalization (PCI).
  • Mysterud, Ivar; Schumacher, Trond; Karlsen, Jan; Tønnesen, Hanne Hjorth; Laane, Carl Morten Motzfeldt & Skulberg, Olav Magnus (2011). Jakten på alveldens "missing link" (15). Sau og geit.  ISSN 0036-5009.  64(5), s 53- 57
  • Sobczynski, Jan; Tønnesen, Hanne Hjorth & Kristensen, Solveig (2011). Physicochemical evaluation of four structurally related meso-porphyrin photosensitizers as part of drug formulation.
  • Sobczynski, Jan; Tønnesen, Hanne Hjorth & Kristensen, Solveig (2011). Physicochemical evaluation of four structurally related meso-porphyrin photosensitizers as part of drug formulation.
  • Tønnesen, Hanne Hjorth (2011). Accelerated photostability testing.
  • Vukicevic, Milica; Randeberg, Lise Lyngsnes; Boschker, Jos Emiel; Tybell, Thomas; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2011). PHOTOINDUCED COLOR CHANGES IN TWO POLYMORFIC FORMS OF RIBOFLAVIN;.
  • Vukicevic, Milica; Randeberg, Lise Lyngsnes; Boschker, Jos Emiel; Tybell, Thomas; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2011). PHOTOINDUCED COLOR CHANGES IN TWO POLYMORFIC FORMS OF RIBOFLAVIN.
  • Hegge, Anne Bee; Andersen, Therese; Melvik, Jan Egil; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2010). In vitro photokilling of Enterococcus faecalis using the natural compound curcumin in vehicles of alginate and cyclodextrin.
  • Hegge, Anne Bee; Andersen, Therese; Melvik, Jan Egil; Bruzell, Ellen; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2010). Phototoxicity of curcumin loaded alginate foams to Enterococcus faecalis and Escherichia coli in vitro.
  • Baertschi, SW; Alsante, KM & Tønnesen, Hanne Hjorth (2010). A Critical Assessment of the ICH Guideline on Photostability Testing of New Drug Substances and Products (Q1B): Recommendation for Revision. Journal of Pharmaceutical Sciences.  ISSN 0022-3549.  99(7), s 2934- 2940 . doi: 10.1002/jps.22076
  • Lilletvedt, Marianne; Tønnesen, Hanne Hjorth; Nardo, Luca; Høgset, Anders & Kristensen, Solveig (2010). Characterization of the spectroscopic properties of the photosensitizers TPCS2a and TPPS2a as part of pharmaceutical preformulation.
  • Tønnesen, Hanne Hjorth & Baertschi, Steven W (2010). Photoreactivity of drugs in vitro and in vivo. [www ].
  • Haukvik, Tone; Bruzell, Ellen; Dragland, Inger Sofie; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Photokilling of Bacteria by Curcumin in Selected Polyethyleneglycol (PEG) Preparations.
  • Haukvik, Tone; Bruzell, Ellen; Dragland, Inger Sofie; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Photokilling of Bacteria by Curcumin in Selected Polyethyleneglycol (PEG) Preparations.
  • Andersen, Kjell-Erik; Fjeldstad, Trygve & Tønnesen, Hanne Hjorth (2009). Det står farmasøyter bak! Kjente produkter med rot i farmasien. Cygnus (Oslo).  ISSN 0809-4039.  15, s 16- 22
  • Benediktsdóttir, Berglind Eva; Gudjónsson, Thorarinn; Tønnesen, Hanne Hjorth; Másson, Már & Baldursson, Ólafur (2009). Curcumin increases transepithelial electrical resistance in vitro.
  • Benediktsdóttir, Berglind Eva; Gudjónsson, Thorarinn; Tønnesen, Hanne Hjorth; Másson, Már & Baldursson, Ólafur (2009). Effects of curcumin and curcuminoids on lung epithelia in vitro.
  • Hegge, Anne Bee; Andersen, Therese; Melvik, Jan Egil; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Effects of excipients on the photostability and drug release in formulations of a novel wound-dressing for Photodynamic Antimicrobial therapy (PACT).
  • Hegge, Anne Bee; Andersen, Therese; Melvik, Jan Egil; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Evaluation of novel alginate foams containing cyclodextrins as drug delivery systems in topical photodynamic therapy of infected wounds.
  • Hegge, Anne Bee; Andersen, Therese; Melvik, Jan Egil; Kristensen, Solveig & Tønnesen, Hanne Hjorth (2009). Preparation and evaluation of novel alginate-wound dressings loaded with a model photosensitizer.
  • Lilletvedt, Marianne; Tønnesen, Hanne Hjorth; Høgset, Anders & Kristensen, Solveig (2009). Spectroscopic evaluation of drug-solvent interactions of the photosensitizers TPCS2a and TPPS2a.

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Publisert 3. nov. 2010 15:45 - Sist endret 15. juni 2017 12:44

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