Ingerid Knudtsen

• Eide, Hanne Astrid; Knudtsen, Ingerid Skjei; Sandhu, Vandana; Løndalen, Ayca; Halvorsen, Ann Rita; Abravan, Azadeh; Kure, Elin Wenche Hegland; Bogsrud, Trond; Brustugun, Odd Terje; Kyte, Jon A; Malinen, Eirik & Helland, Åslaug (2018). Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy. Advances in Radiation Oncology.  ISSN 2452-1094.  3(2), s 130- 138 . doi: 10.1016/j.adro.2017.12.007 Fulltekst i vitenarkiv.
• Abravan, Azadeh; Eide, Hanne Astrid; Knudtsen, Ingerid Skjei; Løndalen, Ayca; Helland, Åslaug & Malinen, Eirik (2017). Assessment of pulmonary 18F-FDG-PET uptake and cytokine profiles in non-small cell lung cancer patients treated with radiotherapy and erlotinib. Clinical and Translational Radiation Oncology.  ISSN 2405-6308.  4, s 57- 63 . doi: 10.1016/j.ctro.2017.04.002
• Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne Astrid; Løndalen, Ayca; Helland, Åslaug; van Luijk, Peter & Malinen, Eirik (2017). A new method to assess pulmonary changes using 18F-fluoro-2-deoxyglucose positron emission tomography for lung cancer patients following radiotherapy. Acta Oncologica.  ISSN 0284-186X.  56(11), s 1597- 1603 . doi: 10.1080/0284186X.2017.1349336
• Knudtsen, Ingerid Skjei; Svestad, Jørund Graadal; Sande, Erlend Peter Skaug; Rekstad, Bernt Louni; Rødal, Jan; van Elmpt, Wouter; Öllers, Michel; Hole, Eli Olaug & Malinen, Eirik (2016). Validation of dose painting of lung tumours using alanine/EPR dosimetry. Physics in Medicine and Biology.  ISSN 0031-9155.  61(6), s 2243- 2254 . doi: 10.1088/0031-9155/61/6/2243
• Arnesen, Marius Røthe; Knudtsen, Ingerid Skjei; Rekstad, Bernt Louni; Eilertsen, Karsten; Dale, Einar; Bruheim, Kjersti; Helland, Åslaug; Løndalen, Ayca Muftuler; Hellebust, Taran Paulsen & Malinen, Eirik (2015). Dose painting by numbers in a standard treatment planning system using inverted dose prescription maps. Acta Oncologica.  ISSN 0284-186X.  54(9), s 1607- 1613 . doi: 10.3109/0284186X.2015.1061690
• Knudtsen, Ingerid Skjei; Aalbergsjø, Siv Gundrosen; Hole, Eli Olaug & Sagstuen, Einar (2015). Radiation effects on crystalline l-asparagine, revisited: Radical formation by EMR and periodic DFT after X-irradiation at 275K. Radiation Physics and Chemistry.  ISSN 0969-806X.  106, s 151- 159 . doi: 10.1016/j.radphyschem.2014.07.008
• Øyen, Live Furnes; Aalbergsjø, Siv Gundrosen; Knudtsen, Ingerid Skjei; Hole, Eli Olaug & Sagstuen, Einar (2015). Direct Radiation Effects to the Amino Acid Side-Chain: EMR and Periodic DFT of X-Irradiated L-Asparagine at 6 K. Journal of Physical Chemistry B.  ISSN 1520-6106.  119(2), s 491- 502 . doi: 10.1021/jp5115866 Vis sammendrag

  Radical formation in single crystals of L-asparagine monohydrate following X-irradiation at 6 K has been investigated at 6 K and at elevated temperatures using various Electron Magnetic Resonance (EMR) techniques like Electron Paramagnetic Resonance (EPR), Electron Nuclear DOuble Resonance (ENDOR) and ENDOR-Induced EPR (EIE) spectroscopy. Molecular structures of the three free radicals stable at 6K were assessed by detailed analysis of the experimental data and Density Functional Theory (DFT) calculations in a periodic approach. Radical LI is assumed to result from one-electron reduction at the amide functional group in the asparagine side chain followed by protonation at the amide carbonyl oxygen by proton transfer from a neighboring molecule across a hydrogen bond. Radical LII is assigned to an one-electron reduction of the carboxyl group in amino acid backbone, followed by proton transfer across a hydrogen bond between a carboxylic oxygen and a neighboring asparagine molecule. Radical LIII is suggested formed by a net CO2 abstraction from an initial one-electron oxidized amino acid backbone. For the DFT modeling of LIII at 6 K, it was chosen to include the CO2 group stably embedded in the crystalline lattice. The assignments made are discussed in relation to previous work on L-asparagine. The relevance of these results to possible charge transfer processes in protein-DNA complexes is discussed.

• Knudtsen, Ingerid Skjei; van Elmpt, Wouter; Öllers, Michel & Malinen, Eirik (2014). Impact of PET reconstruction algorithm and threshold on dose painting of non-small cell lung cancer. Radiotherapy and Oncology.  ISSN 0167-8140.  113(2), s 210- 214 . doi: 10.1016/j.radonc.2014.09.012
• Skretting, Arne; Revheim, Mona Elisabeth; Knudtsen, Ingerid Skjei; Johnsrud, Kjersti & Bogsrud, Trond (2013). An implementation of time-efficient respiratory-gated PET acquisition by repeated breath-holds. Acta Radiologica.  ISSN 0284-1851.  54(6), s 672- 675 . doi: 10.1177/0284185113478007
• Knudtsen, Ingerid Skjei; Rødal, Jan; Brustugun, Odd Terje; Helland, Åslaug; Skretting, Arne & Malinen, Eirik (2011). Dynamic respiratory gated (18)FDG-PET of lung tumors - a feasibility study. Acta Oncologica.  ISSN 0284-186X.  50(6), s 889- 896 . doi: 10.3109/0284186X.2011.583266
• Malinen, Eirik; Rødal, Jan; Knudtsen, Ingerid Skjei; Søvik, Åste & Skogmo, Hege Kippenes (2011). Spatiotemporal analysis of tumor uptake patterns in dynamic (18)FDG-PET and dynamic contrast enhanced CT. Acta Oncologica.  ISSN 0284-186X.  50(6), s 873- 882 . doi: 10.3109/0284186X.2011.579161
• Rødal, Jan; Søvik, Åste; Skogmo, Hege K.; Knudtsen, Ingerid Skjei & Malinen, Eirik (2010). Feasibility of contrast-enhanced cone-beam CT for target localization and treatment monitoring. Radiotherapy and Oncology.  ISSN 0167-8140.  97(3), s 521- 524 . doi: 10.1016/j.radonc.2010.07.006 Vis sammendrag

  A dog with a spontaneous maxillary tumour was given 40 Gy of fractionated radiotherapy. At five out of 10 fractions cone-beam CT (CBCT) imaging before and after administration of an iodinated contrast agent were performed. Contrast enhancement maps were overlaid on the pre-contrast CBCT images. The tumour was clearly visualized in the images thus produced.

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• Grøndahl, Aurora Rosvoll; Knudtsen, Ingerid Skjei; Mulstad, Martine; Tomic, Oliver; Moe, Yngve Mardal; Indahl, Ulf Geir; Torheim, Turid Katrine Gjerstad; Dale, Einar; Malinen, Eirik & Futsæther, Cecilia Marie (2019). Automatic tumour delineation of head and neck cancers in PET/CT images using thresholding and machine learning methods.
• Grøndahl, Aurora Rosvoll; Midtfjord, Alise Danielle; Langberg, Geir Severin Rakh Elvatun; Tomic, Oliver; Indahl, Ulf Geir; Knudtsen, Ingerid Skjei; Malinen, Eirik; Dale, Einar & Futsæther, Cecilia Marie (2019). Prediction of treatment outcome for head and neck cancers using radiomics of PET/CT images. Radiotherapy and Oncology.  ISSN 0167-8140.  133, s 526- 526
• Grøndahl, Aurora Rosvoll; Mulstad, Martine; Moe, Yngve Mardal; Knudtsen, Ingerid Skjei; Torheim, Turid Katrine Gjerstad; Tomic, Oliver; Indahl, Ulf Geir; Malinen, Eirik; Dale, Einar & Futsæther, Cecilia Marie (2019). Comparison of automatic tumour segmentation approaches for head and neck cancers in PET/CT images. Radiotherapy and Oncology.  ISSN 0167-8140.  133, s 557- 557
• Knudtsen, Ingerid Skjei; Rusten, Espen; Grøndahl, Aurora Rosvoll; Furre, Torbjørn; Hellebust, Taran Paulsen; Futsæther, Cecilia Marie; Dale, Einar & Malinen, Eirik (2019). The BIORADIANCE project.
• Langberg, Geir Severin; Grøndahl, Aurora Rosvoll; Midtfjord, Alise Danielle; Tomic, Oliver; Liland, Kristian Hovde; Knudtsen, Ingerid Skjei; Dale, Einar; Malinen, Eirik & Futsæther, Cecilia Marie (2019). Establishing a complete radiomics framework for biomarker identification and outcome prediction using PET/CT images of head & neck cancers.
• Grøndahl, Aurora Rosvoll; Kuttner, Samuel; Elschot, Mattijs; Bathen, Tone Frost; Sundset, Rune; Knudtsen, Ingerid Skjei & Futsæther, Cecilia Marie (2018). Maskinlæring og medisinske bilder for bedre diagnostikk og persontilpasset kreftbehandling. HMT - Helsetjenesten Medisinsk Teknikk : helse, medisin, teknikk.  ISSN 1501-7729.  5
• Knudtsen, Ingerid Søberg Skjei; Eide, Hanne Astrid; Løndalen, Ayca; Abravan, Azadeh; Bogsrud, Trond; Sprauten, Mette; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2017). 18FDG-PET/CT for assessing short-term therapy response of advanced non-small cell lung cancer patients.
• Papoutsis, iosif; Arnesen, Marius Røthe; Sande, Erlend P. S.; Sagstuen, Einar; Knudtsen, Ingerid Skjei & Malinen, Eirik (2017). From dose prescription to dose delivery - can dose painting by numbers be accurately delivered?.
• Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne Astrid; Helland, Åslaug; van Luijk, Peter & Malinen, Eirik (2016). PET based response assessment of lung toxicity - assessment of two approaches for dose response. Radiotherapy and Oncology.  ISSN 0167-8140.  119, s 450- 450
• Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2015). FDG-PET response in the normal lung for lung cancer patients receiving fractionated radiotherapy and erlotinib. Radiotherapy and Oncology.  ISSN 0167-8140.  115, s s634- s634 . doi: 10.1016/S0167-8140(15)41159-4
• Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne Astrid; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2014). Assessing glycolytic response in normal tissues following fractionated radiotherapy.
• Abravan, Azadeh; Knudtsen, Ingerid Skjei; Eide, Hanne; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2014). Monitoring changes in lung glucose metabolism for patients with lung cancer receiving thoracic irradiation. Radiotherapy and Oncology.  ISSN 0167-8140.  111, s 664- 664
• Knudtsen, Ingerid Skjei; Eide, Hanne; Løndalen, Ayca Muftuler; Bogsrud, Trond Velde; Brustugun, Odd Terje; Helland, Åslaug & Malinen, Eirik (2014). 18FDG-PET/CT evaluation of non-small cell lung cancer patients receiving radiotherapy and erlotinib. Radiotherapy and Oncology.  ISSN 0167-8140.  111, s 667- 667
• Øyen, Live Furnes; Aalbergsjø, Siv Gundrosen; Knudtsen, Ingerid Skjei; Hole, Eli Olaug & Sagstuen, Einar (2014). Primary radiation-induced radicals in l-asparagine monohydrate at 6 K: EMR and DFT-PBC studies.
• Knudtsen, Ingerid Skjei; van Elmpt, Wouter; Öllers, Michel; De Ruysscher, Dirk & Malinen, Eirik (2013). Impact of PET reconstruction algorithm on dose painting strategies. Radiotherapy and Oncology.  ISSN 0167-8140.  106, s 229- 229
• Svestad, Jørund; Knudtsen, Ingerid Skjei; Sande, Erlend Peter Skaug; Rekstad, Bernt Louni; Rødal, Jan; van Elmpt, Wouter; Öllers, Michel; Hole, Eli Olaug & Malinen, Eirik (2013). PET-guided simultaneous integrated boost of lung tumors: Alanine/EPR dosimetry in an anthropomorphic phantom. Radiotherapy and Oncology.  ISSN 0167-8140.  106, s 292- 292
• Knudtsen, Ingerid Skjei; van Elmpt, Wouter; Öllers, Michel; De Ruysscher, Dirk & Malinen, Eirik (2012). IMPACT OF PET IMAGE RECONSTRUCTION ON BOOST VOLUME DEFINITION FOR BIOLOGIC IMAGE GUIDED RADIOTHERAPY OF LUNG TUMORS. Radiotherapy and Oncology.  ISSN 0167-8140.  103, s 335- 335
• Knudtsen, Ingerid Skjei; Rødal, Jan; Brustugun, Odd Terje; Helland, Åslaug; Skretting, Arne & Malinen, Eirik (2011). DYNAMIC RESPIRATORY GATED FDG-PET OF LUNG CANCER FOR RADIOTHERAPY PLANNING AND TUMOR CHARACTERIZATION. Radiotherapy and Oncology.  ISSN 0167-8140.  99, s 431- 431
• Knudtsen, Ingerid Skjei; Hole, Eli Olaug & Sagstuen, Einar (2008). Strålingsindusert radikaldannelse i enkrystaller av l-asparagin monohydrat ved 295 K.

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