Jorrit Martijn Enserink

Norwegian version of this page
Visiting address Blindernveien 31 0371 Oslo
Postal address Postboks 1066 Blindern 0316 Oslo


  • Ramos Alonso, Lucia; Garcia Llorente, Ignacio; Enserink, Jorrit & Chymkowitch, Pierre (2022). Analysis of the pheromone signaling pathway by RT-qPCR in the budding yeast Saccharomyces cerevisiae. STAR Protocols. ISSN 2666-1667. 3(1). doi: 10.1016/j.xpro.2022.101210.
  • Zhao, Xu; Hendriks, Ivo A; Le Gras, Stephanie; Ye, Tao; Ramos Alonso, Lucia & Nguéa P, Aurélie [Show all 13 contributors for this article] (2022). Waves of sumoylation support transcription dynamics during adipocyte differentiation. Nucleic Acids Research (NAR). ISSN 0305-1048. 50(3), p. 1351–1369. doi: 10.1093/nar/gkac027.
  • Enserink, Jorrit & Chymkowitch, Pierre (2022). Cell Cycle-Dependent Transcription: The Cyclin Dependent Kinase Cdk1 Is a Direct Regulator of Basal Transcription Machineries. International Journal of Molecular Sciences. ISSN 1661-6596. 23(3). doi: 10.3390/ijms23031293.
  • Melvold, Katrine; Giliberto, Mariaserena; Karlsen, Linda; Ayuda-Duran, Maria del Pilar; Hanes, Robert & Holien, Toril [Show all 11 contributors for this article] (2021). Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies. Molecular Oncology. ISSN 1574-7891. p. 1–18. doi: 10.1002/1878-0261.13153. Full text in Research Archive
  • Garcia Llorente, Ignacio; Orellana Munoz, Sara; Ramos Alonso, Lucia; Andersen, Aram Nikolai; Zimmermann, Christine & Eriksson, Jens [Show all 11 contributors for this article] (2021). Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway. Cell reports. ISSN 2211-1247. 37(13), p. 1–20. doi: 10.1016/j.celrep.2021.110186. Full text in Research Archive
  • Rønneberg, Leiv; Cremaschi, Andrea; Hanes, Robert; Enserink, Jorrit & Zucknick, Manuela (2021). bayesynergy: flexible Bayesian modelling of synergistic interaction effects in in vitro drug combination experiments. Briefings in Bioinformatics. ISSN 1467-5463. 22(6), p. 1–12. doi: 10.1093/bib/bbab251. Full text in Research Archive
  • Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud Khaled; Abdoli, Asghar & Abudu, Yakubu Princely [Show all 50 contributors for this article] (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) . Autophagy. ISSN 1554-8627. 17(1), p. 1–382. doi: 10.1080/15548627.2020.1797280.
  • Caulier, Benjamin William; Enserink, Jorrit & Wälchli, Sébastien (2021). Pharmacologic control of CAR T cells. International Journal of Molecular Sciences. ISSN 1661-6596. 22(9), p. 1–23. doi: 10.3390/ijms22094320. Full text in Research Archive
  • Grad, Iwona; Hanes, Robert; Ayuda-Duran, Maria del Pilar; Kuijjer, Marieke Lydia; Enserink, Jorrit & Meza, Leonardo Zepeda [Show all 7 contributors for this article] (2021). Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening. PLOS ONE. ISSN 1932-6203. 16(3), p. 1–23. doi: 10.1371/journal.pone.0248140. Full text in Research Archive
  • Tadele, Dagim Shiferaw; Robertson, Joseph; Crispin, Richard; Herrera, Carmen; Chlubnová, Markéta & Piechaczyk, Laure Isabelle [Show all 14 contributors for this article] (2020). A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation. Journal of Biological Chemistry. ISSN 0021-9258. 296. doi: 10.1074/jbc.RA120.015285.
  • Omsland, Maria; Andresen, Vibeke; Gullaksen, Stein-Erik; Ayuda-Duran, Maria del Pilar; Popa, Mihaela Lucia & Hovland, Randi [Show all 10 contributors for this article] (2020). Tyrosine kinase inhibitors and interferon‐α increase tunneling nanotube (TNT) formation and cell adhesion in chronic myeloid leukemia (CML) cell lines (. The FASEB Journal. ISSN 0892-6638. 34, p. 3774–3791. doi: 10.1096/fj.201802061RR.
  • Nguéa P, Aurélie; Robertson, Joseph; Herrera, Maria Carmen; Chymkowitch, Pierre & Enserink, Jorrit (2019). Desumoylation of RNA polymerase III lies at the core of the Sumo stress response in yeast. Journal of Biological Chemistry. ISSN 0021-9258. 294(49), p. 18784–18795. doi: 10.1074/jbc.RA119.009721. Full text in Research Archive
  • Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard & Manaf, Adeel [Show all 16 contributors for this article] (2019). 5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication. Scientific Reports. ISSN 2045-2322. 9. doi: 10.1038/s41598-019-47528-3. Full text in Research Archive
  • Herrera, Maria Carmen; Chymkowitch, Pierre; Robertson, Joseph; Eriksson, Jens; Bøe, Stig Ove & Alseth, Ingrun [Show all 7 contributors for this article] (2018). Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity. Nucleic Acids Research (NAR). ISSN 0305-1048. 46(22), p. 11698–11711. doi: 10.1093/nar/gky846. Full text in Research Archive
  • Kruitwagen, Tom; Chymkowitch, Pierre; Denoth-Lippuner, Annina; Enserink, Jorrit & Barral, Yves (2018). Centromeres License the Mitotic Condensation of Yeast Chromosome Arms. Cell. ISSN 0092-8674. 175(3), p. 780–795.e15. doi: 10.1016/j.cell.2018.09.012. Full text in Research Archive
  • Chymkowitch, Pierre & Enserink, Jorrit (2018). Regulation of tRNA synthesis by posttranslational modifications of RNA polymerase III subunits. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms. ISSN 1874-9399. 1861(4), p. 310–319. doi: 10.1016/j.bbagrm.2017.11.001.
  • Zimmermann, Christine; Garcia Llorente, Ignacio; Omerzu, Manja; Chymkowitch, Pierre; Zhang, Beibei & Enserink, Jorrit (2017). Mapping the synthetic dosage lethality network of CDK1/CDC28. G3: Genes, Genomes, Genetics. ISSN 2160-1836. 7(6), p. 1753–1766. doi: 10.1534/g3.117.042317. Full text in Research Archive
  • Pietarinen, Paavo O; Eide, Christopher A; Ayuda-Duran, Maria del Pilar; Potdar, Swapnil; Kuusanmäki, Heikki & Andersson, Emma I [Show all 18 contributors for this article] (2017). Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors. OncoTarget. ISSN 1949-2553. 8(14), p. 22606–22615. doi: 10.18632/oncotarget.15146. Full text in Research Archive
  • Enserink, Jorrit (2017). Regulation of cellular processes by SUMO: Understudied topics. Advances in Experimental Medicine and Biology. ISSN 0065-2598. 963, p. 89–97. doi: 10.1007/978-3-319-50044-7_5.
  • Chymkowitch, Pierre; Nguéa P, Aurélie; Aanes, Håvard; Robertson, Joseph; Klungland, Arne & Enserink, Jorrit (2017). TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 114(5), p. 1039–1044. doi: 10.1073/pnas.1615093114.
  • Chymkowitch, Pierre; Nguéa P, Aurélie & Enserink, Jorrit (2015). SUMO-regulated transcription: Challenging the dogma. Bioessays. ISSN 0265-9247. 37(10), p. 1095–1105. doi: 10.1002/bies.201500065.
  • Chymkowitch, Pierre; Nguéa P, Aurélie; Aanes, Håvard; Koehler, Christian; Thiede, Bernd & Lorenz, Susanne [Show all 9 contributors for this article] (2015). Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes. Genome Research. ISSN 1088-9051. 25(6), p. 897–906. doi: 10.1101/gr.185793.114.
  • Enserink, Jorrit (2015). Sumo and the cellular stress response. Cell Division. ISSN 1747-1028. 10. doi: 10.1186/s13008-015-0010-1.
  • Davydova, Erna; Ho, Angela Yeuan Yen; Malecki, Jedrzej Mieczyslaw; Moen, Anders; Enserink, Jorrit & Jakobsson, Magnus [Show all 8 contributors for this article] (2014). Identification and characterization of a novel evolutionarily conserved lysine-specific methyltransferase targeting eukaryotic translation elongation factor 2 (eEF2). Journal of Biological Chemistry. ISSN 0021-9258. 289(44), p. 30499–30510. doi: 10.1074/jbc.M114.601658.
  • Chymkowitch, Pierre & Enserink, Jorrit (2013). The cell cycle rallies the transcription cycle: Cdc28/Cdk1 is a cell cycle-regulated transcriptional CDK. Transcription. ISSN 2154-1264. 4(1), p. 3–6. doi: 10.4161/trns.22456.
  • Zimmermann, Christine; Santos, Aline; Gable, Kenneth; Epstein, Sharon; Gururaj, Charulatha & Chymkowitch, Pierre [Show all 16 contributors for this article] (2013). TORC1 Inhibits GSK3-Mediated Elo2 Phosphorylation to Regulate Very Long Chain Fatty Acid Synthesis and Autophagy. Cell reports. ISSN 2211-1247. 5(4), p. 1036–1046. doi: 10.1016/j.celrep.2013.10.024.
  • Chymkowitch, Pierre; Eldholm, Vegard; Lorenz, Susanne; Zimmermann, Christine; Lindvall, Jessica M. & Bjørås, Magnar [Show all 8 contributors for this article] (2012). Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 109(26), p. 10450–10455. doi: 10.1073/pnas.1200067109.
  • Enserink, Jorrit & Kolodner, Richard D. (2012). What makes the engine hum: Rad6, a cell cycle supercharger. Cell Cycle. ISSN 1538-4101. 11(2), p. 249–252. doi: 10.4161/cc.11.2.19023.
  • Pultz, Dennis; Bennetzen, Martin V.; Rodkær, Steven Vestergaard; Zimmermann, Christine; Enserink, Jorrit & Andersen, Jens S. [Show all 7 contributors for this article] (2012). Global mapping of protein phosphorylation events identifies Ste20, Sch9 and the cell-cycle regulatory kinases Cdc28/Pho85 as mediators of fatty acid starvation responses in Saccharomyces cerevisiae. Molecular Biosystems. ISSN 1742-206X. 8(3), p. 796–803. doi: 10.1039/c2mb05356j.
  • Enserink, Jorrit (2012). Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways. Molecules. ISSN 1420-3049. 17(8), p. 9258–9273. doi: 10.3390/molecules17089258.
  • Zimmermann, Christine; Chymkowitch, Pierre; Eldholm, Vegard; Putnam, Christopher D.; Lindvall, Jessica Margareta & Omerzu, Manja [Show all 9 contributors for this article] (2011). A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 108(46), p. 18748–18753. doi: 10.1073/pnas.1115885108.
  • Enserink, Jorrit & Kolodner, Richard D. (2010). An overview of Cdk1-controlled targets and processes. Cell Division. ISSN 1747-1028. 5. doi: 10.1186/1747-1028-5-11.
  • Kats, Ellen S; Enserink, Jorrit; Martinez, Sandra & Kolodner, RD (2009). The Saccharomyces cerevisiae Rad6 Postreplication Repair and Siz1/Srs2 Homologous Recombination-Inhibiting Pathways Process DNA Damage That Arises in asf1 Mutants. Molecular and Cellular Biology. ISSN 0270-7306. 29(19), p. 5226–5237. doi: 10.1128/MCB.00894-09.
  • Enserink, Jorrit; Hombauer, Hans; Huang, Meng-Er & Kolonder, Richard D. (2009). Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. Journal of Cell Biology. ISSN 0021-9525. 185(3), p. 423–437. doi: 10.1083/jcb.200811083.
  • Bryn, Tone; Mahic, Milada; Enserink, Jorrit; Schwede, Frank; Aandahl, Einar Martin & Tasken, Kjetil (2006). The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages. Journal of Immunology. ISSN 0022-1767. 176.
  • Enserink, Jorrit; Smolka, Marcus B.; Zhou, Huilin & Kolodner, Richard D. (2006). Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae. Journal of Cell Biology. ISSN 0021-9525. 175(5), p. 729–741. doi: 10.1083/jcb.200605080.
  • Enserink, Jorrit; Smolka, Marcus B.; Chen, Sheng-hong; Maddox, Paul S.; Albuquerque, Claudio P. & Wei, Xiao X. [Show all 9 contributors for this article] (2006). An FHA domain–mediated protein interaction network of Rad53 reveals its role in polarized cell growth. Journal of Cell Biology. ISSN 0021-9525. 175(5), p. 743–753. doi: 10.1083/jcb.200605081.
  • Vang, Torkel; Abrahamsen, Hilde; Myklebust, Sondre; Enserink, Jorrit; Prydz, Hans Peter B & Mustelin, Tomas [Show all 8 contributors for this article] (2004). Csk knockdown by RNA interference augments T cell receptor-mediated signaling in normal, peripheral T cells. European Journal of Immunology. ISSN 0014-2980. p. 2191–2199.
  • Enserink, Jorrit; Price, L.; Methi, Trond; Mahic, Milada; Sonnenberg, A. & Bos, Johannes L. [Show all 7 contributors for this article] (2004). cAMP, Epac and Rap1 regulate adhesion to laminin-5 through the alfa3beta1 integrin but not the alfa6beta4 integrin. Journal of Biological Chemistry. ISSN 0021-9258. 279, p. 44889–44896.
  • Enserink, Jorrit; Bos, Johanes L.; de Bruyn, K.; Kuiperij, Bea; Rangarajan, Savithri & Riedl, John [Show all 9 contributors for this article] (2003). The role of Rap1 in integrin-mediated cell adhesion. Biochemical Society Transactions. ISSN 0300-5127. p. 83–86.
  • Enserink, Jorrit; Rangarajan, Savithri; Kuiperij, Bea; de Rooij, Johan; Price, Leo S. & Schwede, Frank [Show all 7 contributors for this article] (2003). Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β2-adrenergic receptor. Journal of Cell Biology. ISSN 0021-9525. 160(4), p. 487–493. doi: 10.1083/jcb.200209105.
  • Enserink, Jorrit; Verschure, Pernette J.; van der Kraan, Ineke; Moné, Martijn J.; Manders, Erik M.M. & van Driel, Roel (2002). Large-scale Chromatin Organization and the Localization of Proteins Involved in Gene Expression in Human Cells. Journal of Histochemistry and Cytochemistry. ISSN 0022-1554. 50(10), p. 1303–1312. doi: 10.1177/002215540205001003.
  • Enserink, Jorrit; Staal, Ada; Stein, Janet L.; Stein, Gary S. & van Wijnen, Andre J. (2000). Molecular characterization of Celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2. Journal of Cellular Physiology. ISSN 0021-9541. 185(2), p. 269–279. doi: 10.1002/1097-4652%28200011%29.

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  • Enserink, Jorrit (2022). Brukermedvirkning i Kreftforskning.
  • Enserink, Jorrit (2022). Brukermedvirkning - Forskernes perspektiv.
  • Enserink, Jorrit (2022). Novel Methods for Stratification of Acute Myeloid Leukemia .
  • Zhang, Beibei; Ayuda-Duran, Maria del Pilar; Piechaczyk, Laure Isabelle; Fløisand, Yngvar; Mayoral Safont, Mireia & Karlsen, Ida Tveit [Show all 14 contributors for this article] (2019). GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells. Haematologica. ISSN 0390-6078. 104(5). doi: 10.3324/haematol.2019.220533.
  • Ayuda-Duran, Maria del Pilar; Zhang, B; Piechaczyck, L.; Popa, Mihaela Lucia; Tadele, Dagim Shiferaw & Rowe, Alexander D. [Show all 12 contributors for this article] (2017). a precision medicin platform for acute myeloid leukemia to help unraveling the molecular addictions of FLT3-ITD-driven AML.
  • Enserink, Jorrit (2013). Cdk1 is part of a network of priming kinases that directly regulate the basal transcription machinery. Yeast. ISSN 0749-503X. 30, p. 66–66.
  • Zimmermann, Christine; Chymkowitch, Pierre; Eldholm, Vegard; Putnam, Christopher D.; Lindvall, Jessica M. & Omerzu, Manja [Show all 9 contributors for this article] (2012). A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression. The FASEB Journal. ISSN 0892-6638. 26.
  • Enserink, Jorrit; Christensen, Anne Elisabeth; de Rooij, Johan; van Triest, Miranda; Schwede, Frank & Genieser, Hans-Gottfried [Show all 9 contributors for this article] (2002). A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. Nature Cell Biology. ISSN 1465-7392. 4(11), p. 901–906.

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Published Dec. 8, 2021 10:41 AM - Last modified Dec. 8, 2021 10:41 AM


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