We have for some 20 years worked on comparative respiratory and circulatory physiology, and comparative neurobiology
The Sandlie group studied the structure and function of antibodies and T-cell receptors, the specific detection molecules of the adaptive immune system. The purpose of the work was to engineer antibodies and other molecules for use in therapy and research.
In our group we study a wide range of questions in ecology, evolution, and archaeology using (ancient) DNA and genomics.
Anti-microbial/bacterial peptides (AMPs) are widely distributed in nature; they are produced by bacteria, plants and a wide variety of animals - both invertebrates and vertebrates.
The Falnes group's main research interest is the identification and characterisation of novel human enzymes, in particular so-called methyltransferases that target nucleic acids and proteins to regulate their function.
This page is under reconstruction.
Our research aims to understand how membrane traffic is regulated in eukaryotic cells, and how it functions in concert with the cytoskeleton.
Our research focuses on the molecular mechanisms by which hormones, in particular the male hormone testosterone, regulate intracellular signaling events resulting in cellular responses. In addition, we are interested in stress signaling pathways and their functional role in normal and cancer cells. We are studying how disruption in these signaling events, especially in prostate cancer cells, have disease promotion effects.
CELS will address fundamental biological questions related to the genotype-phenotype paradigm in an evolutionary context using a computational inference approach
The Centre for Ecological and Evolutionary Synthesis (CEES) combines a broad spectrum of disciplines (such as population biology, statistical and mathematical modelling, and genomics) to foster the concept of ecology as a driving force of evolution via selective processes, with a corresponding influence of evolutionary changes on ecology.
CIR is a Centre of Exellence that involves groups from The Faculty of Medicine and The Faculty of Mathematics and Natural Sciences.
The Centre for Integrative Microbial Evolution (CIME) (2014-2019) combined expertise in organismal and molecular biology involving taxonomy, phylogenetics, genomics, epigenetics, ecology, evolutionary biology and developmental biology with extensive experience in different model systems to address fundamental questions of microbial evolution.
The Earth BioGenome Project (EBP) is a global non-profit initiative that aims to sequence and catalogue the genomes of all of Earth's 1.5 million currently described eukaryotic species over a period of ten years. EBP-Nor is the Norwegian initiative of EBP, and a partnership among national and international partners.
Gene expression is controlled at many levels. We are interested in uncovering how gene regulation, particularly at the post-transcriptional level, controls fundamental biological processes, including the developmental or metabolic plasticity, explained below, with important biomedical implications. Our experimental models are the genetically tractable nematode, Caenorhabditis elegans, and mammalian cells. Our interdisciplinary approach combines genetics, genomics, molecular biology, and biochemistry.
In bacteria, the cell surface is a key interface for the interaction with different environments. In our research group, we study phenomena such as adhesion, biofilm formation, and membrane transport processes.
Our approach is comparative: how do closely related species of bacteria interact differently with different hosts or surfaces? What are the molecular factors underlying these interactions?
Our projects are often interdisciplinary, and span topics in both basic and applied science. Our methods range from microbiology and structural biology to genome sequencing, chemical analytics and biophysical approaches.
Our model species are typically Gram-negative pathogens. As we are interested in host specificity, we like to look at species groups that have diverse hosts, from human to fish.
The Winnie Eskild group is working with a novel mouse model for liver fibrosis and lysosomal disorders.
Regulation of the cell cycle transitions in eukaryotes.
Marine botany addresses all organisms in aquatic environments that are photosynthetic. Algae and seagrasses are increasingly important to understand as they are the primary producers in water.
Ecology, population dynamics, genomics and bioeconomics of marine fish stocks
Our focus is the developmental biology of plant reproduction, i.e. the generation of plant germlines from a somatic tissue, the differentiation and functional biology of plant gametes, culminating in double fertilization and the development of the embryo and the product of the second fertilization event, the endosperm inside the maternal structures of the seed.
The research in pelagic ecology addresses life and environmental interactions in the free water masses of the sea.
The Aarnes group studies ammonium toxicity in duckweed.
The Klein Group research centers on the molecular machinery that degrades mRNAs in chloroplasts.
The proteomics group provides service and performs independent research on method development.
Our group uses a combination of experimental and computational approaches to analyze and model gene regulation and the life and fate of RNA molecules.
The Structural Redox Enzymology (ROX) group uses a combination of biophysical and biochemical methods to understand the structure and function of redox enzyme systems by using protein crystallography, enzyme kinetics, binding studies and different types of spectroscopies.
This is a consortium of research groups at The Faculty of Mathematics and Natural Sciences, University of Oslo studying the structures, interactions, and functions of complex sugars attached to proteins and lipids.
We are studying pathogenic bacteria, especially N. gonorrhoeae, with a particular focus on how pathogenic bacteria cause disease in man.
The Gabrielsen Group is focusing on understanding the molecular function of one specific transcription factor, c-Myb, a cancer-related transcription factor operating as a regulator of stem and progenitor cells in the bone marrow
We investigate the mechanisms regulating chromatin and gene expression during cellular differentiation and cell cycle progression in yeast and mammals.
We are pursuing two different lines of research.
We study gene regulation, - more specifically, the molecular mechanisms that govern differential regulation of our ~20,000 genes in different cell types, tissues, and organs.