Structural Redox Biochemistry - Hersleth

The Structural Redox Biochemistry (ROX) team uses a combination of biophysical and biochemical methods to understand the structure and function of redox protein systems by using protein crystallography, enzyme kinetics, binding studies and different types of spectroscopies.

We are part of the Section for Biochemistry and Molecular Biology (BMB) at Department of Biosciences and associated with the Section for Chemical Life Sciences (Bio3) at Department of Chemistry.

We focus on three research areas:

  1. Enzyme activation: How are different enzymes activated by redox partner proteins? We are looking at the flavoprotein redox network used to activate ribonucleotide reductase and nitric oxide synthase
  2. Single-crystal spectroscopy: Developing single-crystal spectroscopic methods to understand the redox chemistry in crystal structures determined with protein crystallography.  
  3. Extracellular electron transfer: How does extracellular electron transfer (EET) work in Shewanella bacteria? EET can be important in both the break down of toxic compounds in nature as well as in the production of clean energy. 





Tags: Biochemistry, structural biology, protein structure, protein crystallography, Synchrotron
Published July 2, 2017 9:18 PM - Last modified Oct. 30, 2019 10:04 PM
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