Roberto Rossini

• Rossini, Roberto; Oshaghi, Mohammadsaleh; Nekrasov, Maxim; Bellanger, Aurelie Nathalie Pascale; Domaschenz, Renae & Dijkwel, Yasmin [Show all 10 contributors for this article] (2023). Multi-level 3D genome organization deteriorates during breast cancer progression. bioRxiv. ISSN 2692-8205. doi: 10.1101/2023.11.26.568711.
• Rossini, Roberto; Kumar, Vipin; Mathelier, Anthony; Rognes, Torbjørn & Paulsen, Jonas (2022). MoDLE: high-performance stochastic modeling of DNA loop extrusion interactions. Genome Biology. ISSN 1465-6906. 23(1). doi: 10.1186/s13059-022-02815-7. Full text in Research Archive Show summary

  DNA loop extrusion emerges as a key process establishing genome structure and function. We introduce MoDLE, a computational tool for fast, stochastic modeling of molecular contacts from DNA loop extrusion capable of simulating realistic contact patterns genome wide in a few minutes. MoDLE accurately simulates contact maps in concordance with existing molecular dynamics approaches and with Micro-C data and does so orders of magnitude faster than existing approaches. MoDLE runs efficiently on machines ranging from laptops to high performance computing clusters and opens up for exploratory and predictive modeling of 3D genome structure in a wide range of settings.

• Rossini, Roberto; Kumar, Vipin; Rognes, Torbjorn; Mathelier, Anthony & Paulsen, Jonas (2022). MoDLE: High-performance stochastic modeling of DNA loop extrusion interactions. bioRxiv. ISSN 2692-8205. doi: 10.1101/2022.04.13.488157.

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• Nederbragt, Lex; Lemma, Roza Berhanu; Belova, Tatiana; Cheneby, Jeanne; Ibrahim, Mohamed & Akdeniz, Byram Cevdet [Show all 7 contributors for this article] (2022). Oslo Bioinformatics Workshop Week 2022. Show summary

  December 7th-13th 2022 will see the very first Oslo Bioinformatics Workshop Week at the University of Oslo, Norway. This event is organised by the Student Committee of the Centre for Bioinformatics at UiO, in collaboration with the ISCB Regional Student group in Norway. These workshops are open to the scientific community in Oslo and the surrounding area.

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