Alexander Harald Sandtorv
We focus on development of synthetic methodology for chemical systems with biological activity. Two cyclic structures of interest are hydantoins and indoles, and our current efforts are primarily aimed at novel hydantoin functionalization reactions.
The Sandtorv-group works interdisciplinarly towards pharmacy, medicine, catalysis and theoretical chemistry. Projects in the group have an interdisciplinary dimension, depending on the spesific project and challenges. Typical projects deal with global challenges, such as antibiotic resistance and treatment of cancer.
Assoc. Prof. Sandtorv is also dedicated to teaching and scientific outreach, and is the author of a growing portfolio of books, both fiction and non-fiction. He features frequently in the Norwegian media. He is also a member The Young Academy of Norway
- Organic chemistry I (KJM1111) from spring 2019
- Organic synthesis (KJM5270/KJM9270) from fall 2020
Projects in the group?
We are currently accepting UiO bachelor and masterstudents for projects in the group. If you are interested, please contact Assoc. Prof. Sandtorv directly.
Some projects available for BSc- and MSc-students:
1. Synthesis and design of structures with antibiotic properties. Elucidation of potentially novel mechanism of action in collaboration with the group of Hans-Petter Hersleth (IBV, UiO).
2. Development of novel methods for synthesis of hydantoins with studies on breast cancer cell lines, in collaboration with Assoc. Prof. Antoni Hortado (NCCM, UiO / Barcelona University Hospital.
If you are an external Phd- or postdoc student, we only accept students with a strong record who wish to apply for external funding (ie Marie Curie, etc). No unsolicited applications will be considered (so stop sending them, PLEASE!).
- Brian C. Gilmour (summer student)
- George Peletis (master student)
- Alexander H. Sandtorv, Kjemi - Enkelt forklart, Universitetsforlaget, 2016
- Alexander H. Sandtorv, God kjemi, Kagge forlag, 2018
- Jarle S. Diesen og Alexander H. Sandtorv, Organisk kjemi, Universitetsforlaget, 2018
- Alexander H. Sandtorv, Reaksjoner og mekanismer i organisk kjemi, Universitetsforlaget, 2019
- Alexander H. Sandtorv, Kjemi for ingeniører, Universitetsforlaget, 2019
- Alexander H. Sandtorv, Kjemi enkelt forklart 2. utgave, Universitetsforlaget, 2019
Articles and book chapters after independent career at UiO
- Linn Neerbye Berntsen, Ainara Nova, David S. Wragg and Alexander H. Sandtorv, Cu-catalyzed N-3-arylation of hydantoins using diaryliodonium salts, Org. Lett, 2020, 22, 2687. Link
Selected articles and book chapters prior to independent career at UiO
- Alexander H. Sandtorv and David. R. Stuart, Metal-free Synthesis of Aryl Amines: Beyond Nucleophilic Aromatic Substitution. Angew. Chem. Int. Ed. 2016, 51, 15812-15815, featured in Synfacts (02-2017).
- Alexander H. Sandtorv, Calum Leitch, Siv Lise Bedringaas, Bjørn Tore Gjertsen, and Hans-René Bjørsvik. Synthesis of 4-substituted Ag-NHCs with anti-leukemic effect. Chem. Med. Chem. 2015, 10, 1522-1527. Inside cover of Chem. Med. Chem.
- Alexander H. Sandtorv, Transition Metal Catalyzed C-H Activation of Indoles, Adv. Synth. Catal. 2015, 11, 2403-2435. Most accesses article in Adv. Synth. Catal. for 2015-2016
- Alexander H. Sandtorv and Hans-René Bjørsvik. Fast Halogenation of N-heterocycles by means of N,N'-diiodo-5,5-dimethylhydantoin, Adv. Synth. Catal. 2013, 355, 499–507.
- Alexander H. Sandtorv and Hans-René Bjørsvik. A Three-way switchable Process for the Suzuki Cross Coupling, Hydrodehalogenation, or an Assisted Tandem Hydrodehalogenation and Suzuki Cross Coupling sequence, Adv. Synth. Catal. 2013, 355, 3231-3243.
Brian C. Gilmour (summer student 2019, currently masterstudent at Oslo University Hospital)