Nico König

• Elbers, Mirko; Sternemann, Christian; Julius, Karin; Paulus, Michael; Surmeier, Göran; König, Nico; Nase, Julia; Bolle, Jennifer; Wagner, Ralf; Irifune, Tetsuo & Tolan, Metin (2020). Pressure stability of the first hydration shell of yttrium in aqueous YCl3 solution. High Pressure Research.  ISSN 0895-7959.  40(1), s 194- 204 . doi: 10.1080/08957959.2020.1724998
• König, Nico; Willner, Lutz; Carlström, Göran; Zinn, Thomas; Knudsen, Kenneth Dahl; Rise, Frode; Topgaard, Daniel & Lund, Reidar (2020). Spherical Micelles with Nonspherical Cores: Effect of Chain Packing on the Micellar Shape. Macromolecules.  ISSN 0024-9297.  53(23), s 10686- 10698 . doi: 10.1021/acs.macromol.0c01936 Full text in Research Archive.
• König, Nico; Willner, Lutz; Pipich, Vitaliy; Mahmoudi, Najet & Lund, Reidar (2020). Tale of Two Tails: Molecular Exchange Kinetics of Telechelic Polymer Micelles. Physical Review Letters.  ISSN 0031-9007.  124(19) . doi: 10.1103/PhysRevLett.124.197801
• König, Nico; Willner, Lutz & Lund, Reidar (2019). Structure and thermodynamics of mixed polymeric micelles with crystalline cores: Tuning properties: Via co-assembly. Soft Matter.  ISSN 1744-683X.  15(39), s 7777- 7786 . doi: 10.1039/c9sm01452g
• König, Nico; Willner, Lutz; Pipich, Vitaliy; Zinn, Thomas & Lund, Reidar (2019). Cooperativity during Melting and Molecular Exchange in Micelles with Crystalline Cores. Physical Review Letters.  ISSN 0031-9007.  122(7) . doi: 10.1103/PhysRevLett.122.078001 Full text in Research Archive.
• Julius, Karin; Weine, Jonathan; Berghaus, Melanie; König, Nico; Gao, Mimi; Latarius, Jan; Paulus, Michael; Schroer, Martin; Tolan, Metin & Winter, Roland (2018). Water-mediated protein-protein interactions at high pressures are controlled by a deep-sea osmolyte. Physical Review Letters.  ISSN 0031-9007.  121, s 038101 . doi: 10.1103/physrevlett.121.038101
• König, Nico; Paulus, Michael; Julius, Karin; Schulze, Julian; Voetz, Matthias & Tolan, Metin (2017). Antibodies under pressure: A Small-Angle X-ray Scattering study of Immunoglobulin G under high hydrostatic pressure. Biophysical Chemistry.  ISSN 0301-4622.  231, s 45- 49 . doi: 10.1016/j.bpc.2017.05.016
• Schulze, Julian; Möller, Johannes; Weine, Jonathan; Julius, Karin; König, Nico; Nase, Julia; Paulus, Michael; Tolan, Metin & Winter, Roland (2016). Phase behavior of lysozyme solutions in the liquid–liquid phase coexistence region at high hydrostatic pressures. Physical Chemistry, Chemical Physics - PCCP.  ISSN 1463-9076.  18, s 14252- 14256 . doi: 10.1039/C6CP01791F

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• König, Nico (2020). A Tale of Two Tails - Exchange Kinetics in Telechelic Polymer Micelles.
• König, Nico (2020). Structure and Exchange Kinetics of Nanocrystalline Micelles, Telechelic Hydrogels and Self-Assembling Antimicrobial Peptides. Series of dissertations submitted to the Faculty of Mathematics and Natural Sciences, University of Oslo.. 2286. Show summary

  Self-assembly represents an easy way to create large quantities of various kinds of nanoparticles. Small molecules are “programmed” to self-organize into nanostructures, without external manipulation. These nanostructures are of great commercial interest, not only as drug delivery vehicles but also as components of complex fluids, cleaning materials and other everyday products. In this dissertation, we investigated fundamental laws governing self-assembly. As a model system, we used amphiphilic polymer molecules carrying both water-repellent and water-compatible blocks, which spontaneously self-organize into so-called “micelles” when dispersed in water. We then examined how the self-assembly of these micelles was affected when we blended polymers of different length or when we let them crystallize. We also discovered a new mechanism how molecules move between different micelles. The results of this thesis will help to create more kinds of useful nanoparticles in the future. In addition, we investigated self-assembled structures, so-called “fibers”, of an antimicrobial peptide, a potential new antibiotic. The fibers proved to be extraordinarily stable which is helpful insight for the further development of this drug candidate.

• König, Nico (2018). End of Cooperativity - Chain Exchange Kinetics in Mixed Polymeric Micelles with Partially Crystalline Cores.
• König, Nico (2018). On the Cooperativity during Melting and Molecular Exchange in Micelles with Crystalline Cores.

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