Steven Ray Haakon Wilson

Image of Steven Ray Haakon Wilson
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Phone +47 22844325
Mobile phone 97010953
Room Ø 123
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Visiting address Sem Sælands vei 26 0371 Oslo
Postal address Postboks 1033,Blindern 0315 Oslo

I am a professor of analytical chemistry, specializing in chromatography and mass spectrometry (LC-MS). My current focus is on using LC-MS to study organoids, i.e. lab-grown organs. I am a group leader in a Center of Excellence on this topic (Hybrid Technology Hub). I also have several collaborations with hospitals, related to diagnostics (proteomics, metabolomics). I am also group leader in the Norwegian Network of Advanced Proteomics Infrastructure (NAPI).

I also work as the head of education for the Department of Chemistry. Read my blog here:

I teach several subjects, including analytical chemistry and biochemistry, and have won several teaching awards.

In addition, I am an active science communicator, with many contributions through television, newspapers and radio/podcasts.

 

Tags: Chemistry, Bioanalytical Chemistry

Publications

Recent, selected publications:

Direct Electromembrane Extraction-Based Mass Spectrometry: A Tool for Studying Drug Metabolism Properties of Liver Organoids. Frøydis Sved Skottvoll et al. Analysis and Sensing, 2022, https://doi.org/10.1002/anse.202100051.

On-line reduction of insulin disulfide bonds with photoinduced radical reactions, upstream to nano liquid chromatography-mass spectrometry. Christine Olsen et al. Separation Science Plus, 2022, https://doi.org/10.1002/sscp.202200022.

Bridging the polar and hydrophobic metabolome in single-run untargeted liquid chromatography-mass spectrometry dried blood spot metabolomics for clinical purposes. Hanne Bendiksen Skogvold et al. Journal of Proteome Research, 2021, 20, 8, 4010–4021.

Electromembrane extraction and mass spectrometry for liver organoid drug metabolism studies. Frøydis Sved Skottvoll et al. Analytical Chemistry, 2021, 93, 3576–3585. 

See also my Scholer page for a full list of publications.

View all works in Cristin

  • Wilson, Steven Ray Haakon (2021). "Selected Talk: Direct Coupling of Organ-on-Chip with Electromembrane Extraction and Mass Spectrometry".
  • Moe, Harald; Lundanes, Elsa; Wilson, Steven Ray Haakon; Lund, Reidar & Røberg-Larsen, Hanne (2021). Releasing anitmicrobial peptides through liposomal nanocarriers to fight multidrug-resistant bacteria.
  • Nordli, Henriette; Røberg-Larsen, Hanne; Lundanes, Elsa & Wilson, Steven Ray Haakon (2021). Determination of sterols in liver organoids using liquid chromatography-mass spectrometry (LC-MS).
  • Nordli, Henriette; Aizenshtadt, Aleksandra; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2021). Oxysterols secreted from a Non-Alcoholic Fatty Liver Disease (NAFLD) induced liver organoids.
  • Wiborg, Elisa; Hermansen, Astrid; Olsen, Christine; Wilson, Steven Ray Haakon & Lundanes, Elsa (2021). Silica-based narrow inner diameter open tubular liquid chromatography columns for use in proteomics.
  • Bakketeig, Eris Aas; Olsen, Christine; Berg, Henriette Engen; Nyman, Tuula Anneli; Thiede, Bernd & Lundanes, Elsa [Show all 8 contributors for this article] (2021). Optimization of concatenation of fractions in comprehensive two dimensional liquid chromatography bottom-up proteomics.
  • Olsen, Christine; Lundanes, Elsa & Wilson, Steven Ray Haakon (2021). Disulfide bond reduction upfront liquid chromatography mass spectrometry for protein analysis.
  • Røberg-Larsen, Hanne; Websdale, Alex; Solheim, Stian Kjønnås; Sande, Maria Therese; Hutchinson, Samantha A & Lundanes, Elsa [Show all 8 contributors for this article] (2020). Fast LC-MS for determination of oxysterols in breast cancer tumours.
  • Røberg-Larsen, Hanne & Wilson, Steven Ray Haakon (2020). Low-flow Rate Separations of Lipids. In Griffiths, William & Wang, Yuqing (Ed.), Lipidomics: Current and Emerging Techniques . Royal Society of Chemistry (RSC) Publishing. ISSN 978-1-78801-160-0. p. 49–73. doi: 10.1039/9781788013109-00049.
  • Wilson, Steven Ray Haakon & Gundersen, Lise-Lotte (2020). Fra Tippeligaen til Champions League. Aftenposten (morgenutg. : trykt utg.). ISSN 0804-3116.
  • Skottvoll, Frøydis Sved; Harrison, Sean; Hansen, Frederik; Pedersen-Bjergaard, Stig; Sullivan, Gareth & Bogen, Inger Lise [Show all 8 contributors for this article] (2020). Liver mini-organ analyses using liquid chromatography mass spectrometry.
  • Schüller, Maria; Skottvoll, Frøydis Sved; Lundanes, Elsa & Wilson, Steven Ray Haakon (2020). Bottom-up proteomics of biomarkers to investigate drug-induced hepatotoxicity in human liver organoids as part of preclinical development.
  • Boger, Ida Caroline Sneis; Nerem, Elisabeth; Skottvoll, Frøydis Sved; Harrison, Sean; Sullivan, Gareth & Lundanes, Elsa [Show all 8 contributors for this article] (2020). Determination of liver organoid-induced drug metabolites using liquid chromatography-mass spectrometry (LC-MS)”.
  • Mrša, Ago; Skottvoll, Frøydis Sved; Harrison, Sean; Lundanes, Elsa; Sullivan, Gareth & Wilson, Steven Ray Haakon (2020). Miniaturized liquid chromatography systems for small molecule analysis of organoids.
  • Hermansen, Astrid; Skottvoll, Frøydis Sved; Olsen, Christine; Desmet, Gert; Wilson, Steven Ray Haakon & Lundanes, Elsa (2020). Preparation of porous layer open tubular columns for sensitive proteomics.
  • Olsen, Christine; Scholz, Hanne; Wilson, Steven Ray Haakon & Lundanes, Elsa (2020). Towards online reduction and protein digestion of secreted proteins from pancreatic islets of Langerhans related to diabetes mellitus type I.
  • Flatval, Jonas; Berg, Henriette Engen; Lillerud, Karl Petter; Olsbye, Unni; Nielsen, Claus Jørgen & Wilson, Steven Ray Haakon [Show all 7 contributors for this article] (2020). Retention of nitramines on UiO-66 ZrMOF materials and silica-based reversed phase materials .
  • Andersen, Kari Anne; Flatval, Jonas; Mrša, Ago; Berg, Henriette Engen; Chavan, Sachin Maruti & Olsbye, Unni [Show all 8 contributors for this article] (2020). Metal organic framework material UiO-66 as a stationary phase in liquid chromatography.
  • Berg, Henriette Engen; Hvinden, Ingvild Comfort; Sachse, Daniel; Skaga, Erlend; Lundanes, Elsa & Sandberg, Cecilie [Show all 9 contributors for this article] (2020). Observation of brain cancer cells’ molecular responses to chemotherapy .
  • Berg, Henriette Engen; Halldórsson, Skarphéðinn; Thiede, Bernd; Vik-Mo, Einar O.; Lundanes, Elsa & Wilson, Steven Ray Haakon (2020). Micro pillar array columns for comprehensive proteomics.
  • Skogvold, Hanne Bendiksen; Østeby, Anja; Sandås, Elise Mørk; Rootwelt, Helge; Woldseth, Berit & Wilson, Steven Ray Haakon [Show all 11 contributors for this article] (2019). Effects of storage time on the dried blood spot metabolome.
  • Hermansen, Astrid; Schüller, Maria; Skottvoll, Frøydis Sved; Hara, T; Desmet, Gert & Lundanes, Elsa [Show all 7 contributors for this article] (2019). Protein Analysis of Liver Oganoids with Minaturized LC-MS: Nano and PLOT Format.
  • Wilson, Steven Ray Haakon; Berg, Henriette Engen; Røberg-Larsen, Hanne & Lundanes, Elsa (2019). Hyphenations of one-dimensional capillary liquid chromatography with mass spectrometry: state-of-the-art applications . In Tranchida, Peter & Mondello, Luigi (Ed.), Hyphenations of Capillary Chromatography with Mass Spectrometry. Elsevier. ISSN 9780128096383. p. 319–358.
  • Mrša, Ago; Boger, Ida Caroline Sneis; Nerem, Elisabeth; Skottvoll, Frøydis Sved; Harrison, Sean & Lundanes, Elsa [Show all 9 contributors for this article] (2019). Studying organoid drug metabolism using UHPLC/nanoLC-MS.
  • Skottvoll, Frøydis Sved; Boger, Ida Caroline Sneis; Harrison, Sean; Nerem, Elisabeth; Bogen, Inger Lise & Sullivan, Gareth [Show all 7 contributors for this article] (2019). LC-MS approaches to liver organoid analyses.
  • Berg, Henriette Engen; Skottvoll, Frøydis Sved; Bjørseth, Kamilla; Sæterdal, Kristina Erikstad; Brandtzaeg, Ole Kristian & Vehus, Tore [Show all 11 contributors for this article] (2018). Development of nanoLC column technology for proteomic studies .
  • Skjærvø, Øystein; Pilarova, Veronika; Khalikova, Maria; Reubsaet, Leon; Halvorsen, Trine Grønhaug & Gjelstad, Astrid [Show all 10 contributors for this article] (2018). Those Who Can, Teach: Pharma Stars. The Analytical Scientist. ISSN 2051-4077. 1118, p. 40–45.
  • Skogvold, Hanne Bendiksen; Sandås, Elise Mørk; Østeby, Anja; Rootwelt, Helge; Arnesen, Camilla Elene & Wilson, Steven Ray Haakon [Show all 8 contributors for this article] (2018). Development and evaluation of an LC-Orbitrap MS method for untargeted metabolomics of dried blood spots.
  • Røberg-Larsen, Hanne; Sande, Maria Therese; Hutchinson, Samantha A; Solheim, Stian Kjønnås; Lundanes, Elsa & Thorne, James L [Show all 7 contributors for this article] (2018). Rapid determination of oxysterols in breast cancer tumors.
  • Skjærvø, Øystein; Pilarova, Veronika; Khalikova, Maria; Reubsaet, Leon; Halvorsen, Trine Grønhaug & Gjelstad, Astrid [Show all 10 contributors for this article] (2018). Those Who Can, Teach: Pharma Stars. The Analytical Scientist. ISSN 2051-4077. 1118, p. 40–45.
  • Brandtzaeg, Ole Kristian; Levernæs, Maren Christin Stillesby; Halvorsen, Trine Grønhaug; Reubsaet, Leon; Røen, Bent Tore & Vehus, Tore [Show all 9 contributors for this article] (2018). Online sample processing systems for targeted nano liquid chromatography mass spectrometry bioanalysis.
  • Hassine, Esma Ben; Berg, Henriette Engen; Brandtzaeg, Ole Kristian; Vehus, Tore; Wilson, Steven Ray Haakon & Lundanes, Elsa (2018). Capillary poly(styrene-co-octadecene-co-divinylbenzene) monolithic columns.
  • Skytte Af Sätra, Jenny Marie; Nielsen, Claus Jørgen; Van Bavel, Albert; Lundanes, Elsa & Wilson, Steven Ray Haakon (2018). Developing procedures for trace analysis of small amines in water, using LC-MS and GC-MS.
  • Racz, Beatrix; Zawadzka, Malgorzata Elzbieta; Skytte Af Sätra, Jenny Marie; Ringvold, Amund; Rise, Frode & Lundanes, Elsa [Show all 7 contributors for this article] (2018). Identification of “compound X” in goose aqueous humour.
  • Kular, Ramneet Kaur; Wilson, Steven Ray Haakon; Røberg-Larsen, Hanne & Lundanes, Elsa (2018). Towards ultrafast liquid chromatography of 3’-phosphoadenosine-5’-phosphosulfate using a short hydrophilic interaction chromatography column.
  • Olsen, Christine; Brandtzaeg, Ole Kristian; Lundanes, Elsa & Wilson, Steven Ray Haakon (2018). On-line trapping of proteins with monolith-bound drugs, as a tool in drug target discovery.
  • Hvinden, Ingvild Comfort; Rise, Frode; Berg, Henriette Engen; Lundanes, Elsa & Wilson, Steven Ray Haakon (2018). Approaches to untargeted metabolomics of glioblastoma: NMR and MS.
  • Skottvoll, Frøydis Sved; Nilsen, Ola; Krauss, Stefan; Sullivan, Gareth & Wilson, Steven Ray Haakon (2018). Integrating highly miniaturized LC-MS systems with “Organ on a Chip”; the future of preclinical modelling .
  • Røberg-Larsen, Hanne; Hutchinson, Sam Alex; Solheim, Stian; Wilson, Steven Ray Haakon; Lundanes, Elsa & Thorne, James L (2018). Oxysterols in breast cancer.
  • Brandtzaeg, Ole Kristian; Røen, Bent Tore; Lundanes, Elsa & Wilson, Steven Ray Haakon (2018). Qualitative detection of ricin using a multichannel enzyme reactor coupled online with nano liquid chromatography with mass spectrometry detection.
  • Berg, Henriette Sjånes; Bjørseth, Kamilla; Sæterdal, Kristina Erikstad; Smetop, Tone; Skottvoll, Frøydis Sved & Vehus, Tore [Show all 8 contributors for this article] (2018). Evaluation of isolation methods of glioma exosomes for biomarker discovery.
  • Wilson, Steven Ray Haakon (2017). Smedslunds hjertesukk : Jan Smedslund er for resignert på empiriens vegne. Tidsskrift for Norsk Psykologforening. ISSN 0332-6470. 54(5), p. 488–489.
  • Røberg-Larsen, Hanne; Horne, Hildegunn; Holme, Ane Moe; Holm, Maia Blomhoff; Roland, Marie Cecilie & Michelsen, Trond [Show all 8 contributors for this article] (2017). Human in vivo studies of placenta physiology: oxysterols and metabolomic profiling.
  • Røberg-Larsen, Hanne; Skottvoll, Frøydis Sved; Solheim, Stian; Bjørseth, Kamilla; Thorne, James L & Lundanes, Elsa [Show all 7 contributors for this article] (2017). Oxysterols in cancer.
  • Bakketeig, Eris Aas; Wilson, Steven Ray Haakon; Lundanes, Elsa; Berg, Henriette Engen; Olsen, Christine & Reubsaet, Leon [Show all 8 contributors for this article] (2021). The setup and optimization of a complete global proteomics two-dimensional liquid chromatography system, using Spider Fractionation. Universitetet i Oslo, Det matematisk-naturvitenskapelige fakultet.
  • Erlandsson, Tonje Monica; Wilson, Steven Ray Haakon; Skottvold, Frøydis Sved & Lundanes, Elsa (2021). Investigation of CYP activity in liver organoids by establishing a liquid chromatography-mass spectrometry method for measuring drug metabolism. Universitetet i Oslo, Det matematisk-naturvitenskapelige fakultet.
  • Nordli, Henriette; Wilson, Steven Ray Haakon; Lundanes, Elsa & Røberg-Larsen, Hanne (2021). Towards method miniaturization for determination of sterols in liver organoids: an investigation of nano liquid chromatography-mass spectrometry (nLC-MS). Universitetet i Oslo, Det matematisk-naturvitenskapelige fakultet.
  • Moe, Harald Røsand; Wilson, Steven Ray Haakon; Lundanes, Elsa; Røberg-Larsen, Hanne & Lund, Reidar (2021). Establishing a liquid chromatography-mass spectrometry method for the quantification of colistin A, a last line of defense against antibiotic resistance. Matematisk-naturvitenskapelig fakultet, Universitetet i Oslo.
  • Bergh, Marianne Skov-Skov; Øiestad, Åse Marit Leere; Bogen, Inger Lise & Wilson, Steven Ray Haakon (2020). Fentanyl Analogs: Development of Bioanalytical Methods for Forensic Case Work and Studies of Metabolism and Pharmacodynamic Effects. Matematisk Naturvitenskapelig fakultet, Universitetet i Oslo. ISSN 1501-7710. 2020(2287).
  • Mrša, Ago & Wilson, Steven Ray Haakon (2020). Miniaturized liquid chromatography systems for small molecule analysis of organoids. Kjemisk Institutt, Universitetet i Oslo.
  • Flatval, Jonas; Lundanes, Elsa; Wilson, Steven Ray Haakon; Olsbye, Unni; Nielsen, Claus Jørgen & Berg, Henriette Engen (2020). Retention of nitramines on silica-based reversed phase materials and UiO-66 MOF materials. Kjemisk Institutt, Universitetet i Oslo.
  • Andersen, Kari Anne; Lundanes, Elsa; Berg, Henriette Engen; Wilson, Steven Ray Haakon; Chavan, Sachin Maruti & Lillerud, Karl Petter [Show all 7 contributors for this article] (2020). UiO-66 metal-organic framework materials as stationary phases in liquid chromatography. Kjemisk Institutt, Universitetet i Oslo.
  • Boger, Ida Caroline Sneis; Wilson, Steven Ray Haakon; Skottvoll, Frøydis Sved; Lundanes, Elsa & Bogen, Inger Lise (2020). Determination of liver organoid- and spheroid induced drug metabolites using liquid chromatography-mass spectrometry. Kjemisk Institutt, Universitetet i Oslo.
  • Schüller, Maria; Wilson, Steven Ray Haakon; Lundanes, Elsa & Skottvoll, Frøydis Sved (2020). A targeted proteomics approach for the investigation of drug-induced liver injury in hepatic organoids using nano liquid chromatography mass spectrometry. Kjemisk Institutt, Universitetet i Oslo.
  • Hermansen, Astrid; Skottvoll, Frøydis Sved; Wilson, Steven Ray Haakon & Lundanes, Elsa (2020). Development and implementation of open tubular columns for high-sensitivity liquid chromatography-mass spectrometry proteomics of liver organoids. Kjemisk Institutt, Universitetet i Oslo.
  • Haugan, Hege Sofie; Elgstøen, Katja B. Prestø; Skogvold, Hanne Bendiksen & Wilson, Steven Ray Haakon (2020). Investigating the Lipid Coverage of the Dried Blood Spot Metabolome using Liquid Chromatography – Mass Spectrometry for Global Metabolomics. Kjemisk Institutt, Universitetet i Oslo.
  • Kogler, Stian & Wilson, Steven Ray Haakon (2019). On-line “Organ-in-a-Column” Liquid Chromatography Electrospray Ionization Mass Spectrometry for Drug Metabolism Studies. Kjemisk institutt, Universitetet i Oslo.
  • Riddervold, Jan Thomas & Wilson, Steven Ray Haakon (2019). Immunocapture of oxytocin followed by liquid chromatography-mass-spectrometric detection. Kjemisk institutt, Universitetet i Oslo.
  • Sande, Maria Therese; Wilson, Steven Ray Haakon; Lundanes, Elsa & Røberg-Larsen, Hanne (2019). Enzymatic hydrolysis with cholesterol esterase in the presence of surfactant improves efficiency for sample preparation of side-chain oxysterols in biosamples. Universitetet i Oslo.
  • Olsen, Christine; Wilson, Steven Ray Haakon; Skottvoll, Frøydis Sved; Brandtzaeg, Ole Kristian; Rongved, Pål & Lundanes, Elsa (2019). Synthesis and immobilization of linked Wnt-signaling pathway inhibitor on organic monoliths as a proof-of-concept of a capti remedium ad monolitus reactor for online drug deconvolution. Universitetet i Oslo.
  • Kular, Ramneet Kaur; Wilson, Steven Ray Haakon; Røberg-Larsen, Hanne & Lundanes, Elsa (2018). Towards ultrafast liquid chromatography of 3’-phosphoadenosine-5’-phosphosulfate using zwitterionic hydrophilic interaction liquid chromatography-mass spectrometry. Universitetet i Oslo.
  • Sandås, Elise Mørk; Elgstøen, Katja B. Prestø; Østeby, Anja; Skogvold, Hanne Bendiksen & Wilson, Steven Ray Haakon (2018). Liquid chromatography - Orbitrap mass spectrometry is a useful tool in untargeted metabolomics analysis of dried blood spots in clinical chemistry. Department of Chemistry, Faculty of Mathematics and Natural Sciences.
  • Ben Hassine, Esma; Lundanes, Elsa; Wilson, Steven Ray Haakon; Vehus, Tore; Brandtzaeg, Ole Kristian & Berg, Henriette Engen (2018). Capillary poly(styrene-co-octadecene-co-divinylbenzene) monolithic trap columns for bioanalytical analysis. Department of Chemistry Faculty of Mathematics and Natural Sciences.
  • Racz, Beatrix; Wilson, Steven Ray Haakon; Rise, Frode & Lundanes, Elsa (2018). Identification of a major UV absorbing compound in goose aqueous humour. Kjemisk Institutt, Universitetet i Oslo.
  • Amundsen, Sunniva Furre; Wilson, Steven Ray Haakon; Berg, Henriette Engen; Røberg-Larsen, Hanne & Lundanes, Elsa (2018). Online entrapment of epitope-containing peptides from integrins using immobilized antibodies. Kjemisk Institutt, Universitetet i Oslo.
  • Hvinden, Ingvild Comfort; Wilson, Steven Ray Haakon; Rise, Frode; Berg, Henriette Engen & Lundanes, Elsa (2018). Nuclear magnetic resonance spectroscopy based metabolomics discovers biomarkers of glioblastoma drug response. Kjemisk Institutt, Universitetet i Oslo.
  • Solheim, Stian Kjønnås; Lundanes, Elsa; Wilson, Steven Ray Haakon & Røberg-Larsen, Hanne (2018). Exploring selectivity and sensitivity for oxysterol measurements using liquid chromatography-mass spectrometry (LC-MS). Kjemisk Institutt, Universitetet i Oslo.
  • Vehus, Tore; Wilson, Steven Ray Haakon; Lundanes, Elsa; Krauss, Stefan; Halvorsen, Trine Grønhaug & Morth, Jens Preben (2018). Nano Liquid Chromatography-Tandem Mass Spectrometry Platforms for Determination of Low Abundant Wnt/Beta-Catenin Proteins in Cancer Research. Universitetet i Oslo. ISSN 1501-7710. 2018(1962).
  • Brandtzaeg, Ole Kristian; Wilson, Steven Ray Haakon; Lundanes, Elsa; Reubsaet, Leon; Krauss, Stefan & Martinsen, Ørjan Grøttem (2018). Online sample Preparation Platforms for Targeted Nano Liquid Chromatography Mass Spectrometry Bioanalysis. Universitetet i Oslo. ISSN 1501-7710. 2018(1968).
  • Pabst, Oliver; Martinsen, Ørjan Grøttem; Tronstad, Christian & Wilson, Steven Ray Haakon (2018). Electrical properties of human skin: From linear recordings of exogenous electrodermal activity to non-linear memristor measurements. Universitetet i Oslo. ISSN 1501-7710. 2018(1971).
  • Demir, Deniz; Lundanes, Elsa; Wilson, Steven Ray Haakon; Abele, Silvija & Røberg-Larsen, Hanne (2017). Automatic capillary liquid chromatography tandem mass spectrometry method for pharmaceutical products in environmental water samples. Universitetet i Oslo.
  • Skottvoll, Frøydis Sved; Berg, Henriette Engen; Lund, Kaja; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon & Lundanes, Elsa (2017). Critical evaluation of isolation and characterization techniques of breast cancer exosomes. Universitetet i Oslo.
  • Bjørseth, Kamilla; Wilson, Steven Ray Haakon; Brandtzaeg, Ole Kristian & Lundanes, Elsa (2017). Evaluation of exosome isolation techniques for hydrophilic interaction liquid chromatography-mass spectrometry based metabolomics. Universitetet i Oslo.
  • Skogvold, Hanne Bendiksen; Elgstøen, Katja B. Prestø; Østeby, Anja & Wilson, Steven Ray Haakon (2017). Laboratory diagnostics: Maximizing sensitivity of a Q-Exactive Orbitrap mass spectrometer for untargeted metabolomics of dried blood spots. Universitetet i Oslo.
  • Arnesen, Camilla Elene; Wilson, Steven Ray Haakon; Elgstøen, Katja B. Prestø & Østeby, Anja (2017). Optimization of liquid chromatographic parameters for untargeted metabolomics of dried blood spots. Universitetet i Oslo.

View all works in Cristin

Published Nov. 11, 2010 9:00 AM - Last modified May 11, 2022 12:32 PM

Research groups

  • Bio3
  • Bioanalytical chemistry