Dr. Chloé-Agathe Azencott
Dr. Chloé-Agathe Azencott, Researcher at the Centre for Computational Biology (CBIO) of Mines ParisTech, Institut Curie, and INSERM, Paris, France, will present her work on "Network-guided genome-wide association studies."
Many problems in genomics require the ability to identify relevant features in data sets containing many more orders of magnitude than samples. One such example is genome-wide association studies (GWAS), in which hundreds of thousands of single nucleotide polymorphisms (SNPs) are measured for typically thousands of samples. This setup poses both computational and statistical difficulties.
In my talk I will discuss how to use biological networks, which allow us to understand mutations in their genomic context, to address these issues by building on the hypothesis that genomic regions that are involved in a given phenotype are more likely to be connected on a given biological network than not.
Zoom connection information
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