Ian McKeague: Empirical likelihood based inference for concurrent functional linear regression with applications to wearable device data

his talk discusses a nonparametric inference framework for occupation time curves derived from wearable device data. Such curves provide the total time a subject maintains activity above a given level as a function of that level. Taking advantage of the monotonicity and smoothness properties of these curves, we develop a likelihood ratio approach to construct confidence bands for mean occupation time curves.  An extension to fitting concurrent functional regression models is also developed. Application to wearable device data from an ongoing study of an experimental gene therapy for mitochondrial DNA depletion syndrome will be discussed. Based on joint work with Hsin-Wen Chang (Academia Sinica).

 

Image may contain: Person, Forehead, Nose, Cheek, Smile.

Ian McKeague is Professor of biostatisticsat Mailman School of Public Health, Columbia University

Published Mar. 7, 2024 1:12 PM - Last modified Mar. 13, 2024 2:38 PM