Norwegian version of this page

Chubina Pathma Kumarananthan

Doctoral Research Fellow - Section for Pharmaceutical Chemistry

Email c.p.kumarananthan@farmasi.uio.no

Username

Visiting address Sem Sælands vei 3 Farmasibygningen 0371 Oslo

Postal address Postboks 1068 Blindern 0316 Oslo

Other affiliations Faculty of Mathematics and Natural Sciences (Student)

Download business card

Publications

Roy, Tamal; Pogorilyy, Eduard; Kumarananthan, Chubina Pathma; Kvitastein, Nina Augestad; Foscato, Marco & Törnroos, Karl Wilhelm [Show all 8 contributors for this article] (2024). Synthesis and stability of the [<sup>45</sup>Ti]Ti-DOTA complex: en route towards aza-macrocyclic <sup>45</sup>Ti-based radiopharmaceuticals. Chemical Communications. ISSN 1359-7345. 60, p. 7148–7151. doi: 10.1039/d4cc01800a. Full text in Research Archive Show summary
We report the use of DOTA as a chelator for titanium. The resulting complex is fully characterised and in vitro stability studies reveal its high kinetic inertness against transmetallation and transchelation. The radiolabeling of DOTA with 45Ti, via a guaiacol-based liquid–liquid extraction method, leads to a high radiochemical conversion up to 98%.

Pogorilyy, Eduard; Roy, Tamal; Kumarananthan, Chubina Pathma; Foscato, Marco; Törnroos, Karl Wilhelm & Adamsen, Tom Christian Holm [Show all 7 contributors for this article] (2025). Reactivity of Aza-Macrocycle Chelators with Titanium and Radiolabeling of DOTA with Titanium-45. Nuclear Medicine and Biology. ISSN 0969-8051. 150-151. doi: 10.1016/j.nucmedbio.2025.109231. Full text in Research Archive
Roy, Tamal; Pogorilyy, Eduard; Kumarananthan, Chubina Pathma; Foscato, Marco; Törnroos, Karl Wilhelm & Adamsen, Tom Christian Holm [Show all 7 contributors for this article] (2025). Reactivity of Aza-Macrocycle Chelators with Titanium and Radiolabeling of DOTA with Titanium-45. Full text in Research Archive

Published Sep. 25, 2026 12:47 PM - Last modified Sep. 25, 2026 12:47 PM