Jannike Mørch Andersen

Image of Jannike Mørch Andersen
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Mobile phone +4799036395
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Visiting address Lovisenberggata 6 Oslo University Hospital 0456 OSLO
Postal address Postboks 1068 Blindern 0316 Oslo

Academic interests

  • Prenatal drug exposure
  • Neurobiology
  • Neurotoxicology
  • Opioid addiction

Courses taught

Autumn 2017:

FARM1110 - Pharmacology, Physiology and Cell Biology 1

FRM2000 - Drugs and How They Work Part II

Background

From 2017: Senior researcher (Oslo University Hospital), and associated professor (School of Pharmacy, University of Oslo)

PhD in neurobiology (2003)

Publications

  • Skottvoll, Frøydis Sved; Aizenshtadt, Aleksandra; Hansen, Frederik Andre; Martinez, Mikel Amirola; Andersen, Jannike Mørch & Bogen, Inger Lise [Show all 11 contributors for this article] (2021). Direct Electromembrane Extraction based Mass Spectrometry: A Tool for Studying Drug Metabolism Properties of Liver Organoids. Analysis & Sensing. ISSN 2629-2742. 2(1), p. 1–5. doi: 10.1002/anse.202100051. Full text in Research Archive
  • Zosen, Denis; Hadera, Mussie Ghezu; Lumor, Josephine Sena; Andersen, Jannike Mørch & Paulsen, Ragnhild Elisabeth Heimtun (2021). Chicken embryo as animal model to study drug distribution to the developing brain. Journal of pharmacological and toxicological methods. ISSN 1056-8719. 112, p. 1–5. doi: 10.1016/j.vascn.2021.107105.
  • Tuv, Silja Skogstad; Bergh, Marianne Skov-Skov; Andersen, Jannike Mørch; Steinsland, Synne; Vindenes, Vigdis & Baumann, Michael H. [Show all 8 contributors for this article] (2021). Comparative neuropharmacology and pharmacokinetics of methamphetamine and its thiophene analog methiopropamine in rodents. International Journal of Molecular Sciences. ISSN 1661-6596. 22(21), p. 1–16. doi: 10.3390/ijms222112002.
  • Andersen, Jannike Mørch; Bogen, Inger Lise; Karinen, Ritva Anneli; Brochmann, Gerd-Wenche; Mørland, Jørg Gustav & Vindenes, Vigdis [Show all 7 contributors for this article] (2021). Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study. Addiction. ISSN 0965-2140. 116(11), p. 3104–3112. doi: 10.1111/add.15492. Full text in Research Archive
  • Kongstorp, Mette; Bogen, Inger Lise; Stiris, Tom & Andersen, Jannike Mørch (2020). Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats. Drug and Alcohol Dependence. ISSN 0376-8716. 212(108008), p. 1–9. doi: 10.1016/j.drugalcdep.2020.108008. Full text in Research Archive
  • Kongstorp, Mette; Bogen, Inger Lise; Steinsland, Synne; Nerem, Elisabeth; Salih, Triske Woshyar & Stiris, Tom [Show all 7 contributors for this article] (2020). Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain. International Journal of Developmental Neuroscience. ISSN 0736-5748. 80(5), p. 443–453. doi: 10.1002/jdn.10043. Full text in Research Archive
  • Andersen, Jannike Mørch; Opdal, Siri Hauge; Müller, Christian P. & Boix, Fernando (2020). CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment. Behavioural Brain Research. ISSN 0166-4328. 390, p. 1–14. doi: 10.1016/j.bbr.2020.112676.
  • Andersen, Jannike Mørch; Høiseth, Gudrun & Nygaard, Egil (2020). Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis. Early Human Development. ISSN 0378-3782. 143:104997, p. 1–13. doi: 10.1016/j.earlhumdev.2020.104997. Full text in Research Archive
  • Kongstorp, Mette; Bogen, Inger Lise; Stiris, Tom & Andersen, Jannike Mørch (2019). High accumulation of methadone compared with buprenorphine in fetal rat brain after maternal exposure. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 371(1), p. 130–137. doi: 10.1124/jpet.119.259531.
  • Fjelldal, Marthe Fredheim; Hadera, Mussie Ghezu; Kongstorp, Mette; Austdal, Lars Peter Engeset; Sulovic, Ana & Andersen, Jannike Mørch (2019). Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken. International Journal of Developmental Neuroscience. ISSN 0736-5748. 78(C), p. 19–27. doi: 10.1016/j.ijdevneu.2019.07.009.
  • Kvello, Anne Marte Sjursen; Andersen, Jannike Mørch; Boix, Fernando; Mørland, Jørg & Bogen, Inger Lise (2019). The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice. Addiction Biology. ISSN 1355-6215. p. 1–10. doi: 10.1111/adb.12727. Full text in Research Archive
  • Avvisati, Riccardo; Bogen, Inger Lise; Andersen, Jannike Mørch; Vindenes, Vigdis; Mørland, Jørg & Badiani, Aldo [Show all 7 contributors for this article] (2019). The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat. Neuropharmacology. ISSN 0028-3908. 150, p. 192–199. doi: 10.1016/j.neuropharm.2018.12.023.
  • Kvello, Anne Marte Sjursen; Andersen, Jannike Mørch; Øiestad, Elisabeth Leere; Steinsland, Synne; Aase, Audun & Mørland, Jørg [Show all 7 contributors for this article] (2019). A monoclonal antibody against 6-acetylmorphine protects female mice offspring from adverse behavioral effects induced by prenatal heroin exposure. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 368(1), p. 106–115. doi: 10.1124/jpet.118.251504.
  • Thaulow, Cecilie Hasselø; Øiestad, Åse Marit Leere; Rogde, Sidsel; Andersen, Jannike Mørch; Høiseth, Gudrun & Handal, Marte [Show all 8 contributors for this article] (2018). Can measurements of heroin metabolites in post-mortem matrices other than peripheral blood indicate if death was rapid or delayed? Forensic Science International. ISSN 0379-0738. 290, p. 121–128. doi: 10.1016/j.forsciint.2018.06.041.
  • Thaulow, Cecilie Hasselø; Øiestad, Åse Marit Leere; Rogde, Sidsel; Karinen, Ritva Anneli; Brochmann, Gerd-Wenche & Andersen, Jannike Mørch [Show all 13 contributors for this article] (2018). Metabolites of heroin in several different post-mortem matrices. Journal of Analytical Toxicology. ISSN 0146-4760. 42(5), p. 311–320. doi: 10.1093/jat/bky002.
  • Bergh, Marianne Skov-Skov; Bogen, Inger Lise; Andersen, Jannike Mørch; Øiestad, Åse Marit Leere & Berg, Thomas (2017). Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC–MS/MS. Journal of chromatography. B. ISSN 1570-0232. 1072, p. 161–172. doi: 10.1016/j.jchromb.2017.11.016.
  • Hofer, Tim; Duale, Nur; Muusse, Martine; Eide, Dag Markus; Dahl, Hildegunn & Boix, Fernando [Show all 9 contributors for this article] (2017). Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation. Neurotoxicity research. ISSN 1029-8428. doi: 10.1007/s12640-017-9833-7.
  • Eriksen, Guro Søe; Andersen, Jannike Mørch; Boix, Fernando; Bergh, Marianne Skov-Skov; Vindenes, Vigdis & Rice, Kenner C. [Show all 8 contributors for this article] (2016). Comparison of (+)- and (-)-Naloxone on the acute psychomotor-stimulating effects of heroin, 6-acetylmorphine, and morphine in mice. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 358(2), p. 209–215. doi: 10.1124/jpet.116.233544.
  • Kvello, Anne Marte Sjursen; Andersen, Jannike Mørch; Øiestad, Elisabeth Leere; Mørland, Jørg & Bogen, Inger Lise (2016). Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 358(2), p. 181–189. doi: 10.1124/jpet.116.233510.
  • Bogen, Inger Lise; Boix, Fernando; Nerem, Elisabeth; Mørland, Jørg & Andersen, Jannike Mørch (2014). A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 349(3), p. 568–576. doi: 10.1124/jpet.113.212035.
  • Eriksen, Guro Søe; Andersen, Jannike Mørch; Boix, Fernando & Mørland, Jørg (2014). 3-Methoxynaltrexone is not a selective antagonist for the acute psychomotor stimulating effects of heroin and 6-monoacetylmorphine in mice. Pharmacology, Biochemistry and Behavior. ISSN 0091-3057. 122, p. 82–88. doi: 10.1016/j.pbb.2014.03.018.
  • Thaulow, Cecilie Hasselø; Høiseth, Gudrun; Andersen, Jannike Mørch; Handal, Marte & Mørland, Jørg (2014). Pharmacokinetic interactions between ethanol and heroin: a study on post-mortem cases. Forensic Science International. ISSN 0379-0738. 242, p. 127–134. doi: 10.1016/j.forsciint.2014.06.032.
  • Andersen, Jannike Mørch; Haugen, Karianne Slåtta; Ripel, Åse & Mørland, Jørg (2014). The interference of ethanol with heroin-stimulated psychomotor activation in mice is not related to changed brain concentrations of the active metabolites 6MAM or morphine. Basic & Clinical Pharmacology & Toxicology. ISSN 1742-7835. 114(2), p. 197–201. doi: 10.1111/bcpt.12133.
  • Høiseth, Gudrun; Andersen, Jannike Mørch & Mørland, Jørg (2013). Less glucuronidation of morphine in the presence of ethanol in vivo. European Journal of Clinical Pharmacology. ISSN 0031-6970. 69(9), p. 1683–1687. doi: 10.1007/s00228-013-1533-5.
  • Boix, Fernando; Andersen, Jannike Mørch & Mørland, Jørg (2013). Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice. Addiction Biology. ISSN 1355-6215. 18(1), p. 1–7. doi: 10.1111/j.1369-1600.2010.00298.x.
  • Sankararaman, Aparna; Masiulis, Irene; Richardson, Devon; Andersen, Jannike Mørch; Mørland, Jørg & Eisch, Amelia (2012). Methadone does not alter key parameters of adult hippocampal neurogenesis in the heroin-naive rat. Neuroscience Letters. ISSN 0304-3940. 516(1), p. 99–104. doi: 10.1016/j.neulet.2012.03.066.
  • Andersen, Jannike Mørch; Klykken, Christine & Mørland, Jørg (2012). Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain. Journal of Pharmacy and Pharmacology (JPP). ISSN 0022-3573. 64(6), p. 843–847. doi: 10.1111/j.2042-7158.2012.01469.x.
  • Boix, Fernando; Andersen, Jannike Mørch & Mørland, Jørg (2011). Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice. Addiction Biology. ISSN 1355-6215. 18(1), p. 1–7. doi: 10.1111/j.1369-1600.2010.00298.x.
  • Andersen, Jannike Mørch; Olaussen, Christine Fostveit; Ripel, Åse & Mørland, Jørg (2011). Long-term methadone treatment impairs novelty preference in rats both when present and absent in brain tissue. Pharmacology, Biochemistry and Behavior. ISSN 0091-3057. 98(3), p. 412–416. doi: 10.1016/j.pbb.2011.02.017.
  • Andersen, Jannike Mørch; Ripel, Åse; Boix, Fernando; Normann, Per Trygve & Mørland, Jørg (2009). Increased locomotor activity induced by heroin in mice: pharmacokinetic demonstration of heroin acting as a prodrug for the mediator 6-monoacetylmorphine in vivo. Journal of Pharmacology and Experimental Therapeutics. ISSN 0022-3565. 331(1), p. 153–161. doi: 10.1124/jpet.109.152462.
  • Karinen, Ritva Anneli; Andersen, Jannike Mørch; Ripel, Åse; Hasvold, Inger; Hopen, Anita Braute & Mørland, Jørg [Show all 7 contributors for this article] (2009). Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry. Journal of Analytical Toxicology. ISSN 0146-4760. 33(7), p. 345–350.
  • Zahl, Per Henrik; Gøtzsche, Peter C; Andersen, Jannike Mørch & Mæhlen, Jan (2006). Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics. Danish Medical Bulletin. ISSN 0907-8916. 53(4), p. 438–440.
  • Andersen, Jannike Mørch; Myhre, Oddvar; Aarnes, Halvor; Vestad, Tor Arne & Fonnum, Frode (2003). Identification of the Hydroxyl Radical and Other Reactive Oxygen Species in Human Neutrophil Granulocytes Exposed to a Fragment of the Amyloid Beta Peptide. Free radical research. ISSN 1071-5762. 37(3), p. 269–279.
  • Myhre, Oddvar; Andersen, Jannike Mørch; Aarnes, Halvor & Fonnum, Frode (2003). Evaluation of the probes 2´,7´-dichlorofluorescin diacetate, luminol, and lucigenin as indicatos of reactive species formation. Biochemical Pharmacology. ISSN 0006-2952. 65, p. 1575–1582.
  • Fonnum, Frode; Myhre, Oddvar; Voie, Øyvind Albert; Andersen, Jannike Mørch & Dreiem, Anne (2001). The formation of free radicals in human granulocytes in cerebellar granule cells. ATLA (Alternatives to Laboratory Animals). ISSN 0261-1929. 29(3), p. 283–285.

View all works in Cristin

  • Handal, Marte; Andersen, Jannike Mørch & Nygaard, Egil (2019). Barn født av mødre som bruker opioider under svangerskapet.
  • Nygaard, Egil; Andersen, Jannike Mørch & Høiseth, Gudrun (2019). Long-term outcomes after prenatal exposure to methadone or buprenorphine: A meta-analysis.
  • Andersen, Jannike Mørch; Opdal, Siri Hauge; Müller, Christian P. & Boix, Fernando (2017). Phosphorylation of alpha-CaMKII at Thr286 is not required for the acquisition of morphine-induced condition place preference in mice.
  • Hadera, Mussie Ghezu; Andersen, Jannike Mørch & Paulsen, Ragnhild Elisabeth (2017). Effects of methadone in the developing chicken embryo as a model of neurodevelopmental toxicity. Reproductive Toxicology. ISSN 0890-6238. 72, p. 216–217. doi: 10.1016/j.reprotox.2017.06.030.
  • Bogen, Inger Lise; Boix, Fernando; Nerem, Elisabeth; Mørland, Jørg & Andersen, Jannike Mørch (2013). Prekliniske studier av en heroin-vaksine.
  • Andersen, Jannike Mørch; Haugen, Karianne Slåtta; Ripel, Åse & Mørland, Jørg (2013). Hvorfor er kombinasjonen alkohol og heroin farlig?
  • Andersen, Jannike Mørch; Haugen, Karianne Slåtta; Ripel, Åse & Mørland, Jørg (2013). Hvorfor er alkohol og heroin en farlig kombinasjon?
  • Eriksen, Guro Søe; Andersen, Jannike Mørch; Boix, Fernando & Mørland, Jørg (2013). Vil vi i fremtiden kunne utvikle smertelindrende opioidbaserte preparater uten ruspotensial?
  • Bogen, Inger Lise; Boix, Fernando; Nerem, Elisabeth; Mørland, Jørg & Andersen, Jannike Mørch (2013). Preklinisk studie av en passiv heroinvaksine.
  • Boix, Fernando & Andersen, Jannike Mørch (2013). Avhengighet: en læringsprosess som setter avtrykk i hjernen.
  • Boix, Fernando & Andersen, Jannike Mørch (2013). Avhengighet: en læringsprosess som setter avtrykk i hjernen.
  • Bogen, Inger Lise; Andersen, Jannike Mørch; Boix, Fernando; Nerem, Elisabeth; Normann, Per Trygve & Mørland, Jørg (2012). Heroin abuse and addiction: Heroin metabolism as a key player and possible target for new pharmacotherapy.
  • Sankararaman, Aparna; Richardson, Devon; Andersen, Jannike Mørch; Mørland, Jørg & Eisch, Amelia (2012). Effect of methadone on neurogenesis in rats.
  • Gottås, Andre; Andersen, Jannike Mørch; Boix, Fernando; Handal, Marte; Normann, Per Trygve & Pettersen, Bjørg Sjøgren [Show all 11 contributors for this article] (2012). Heroin virker ikke i hjernen!
  • Eriksen, Guro Søe; Andersen, Jannike Mørch; Boix, Fernando & Mørland, Jørg (2012). Ulike µ-opioide subreseptorer medierer den stimulerende- og smertestillende effekten av heroin, 6MAM og morfin.
  • Gottås, Andre; Andersen, Jannike Mørch; Boix, Fernando; Handal, Marte; Normann, Per Trygve & Pettersen, Bjørg Sjøgren [Show all 11 contributors for this article] (2011). All you learned about how heroin acts in the brain is wrong.
  • Eriksen, Guro Søe; Andersen, Jannike Mørch; Boix, Fernando & Mørland, Jørg (2011). Medieres den lokomotoriske effekten av heroin, 6MAM, morfin og M6G gjennom forskjellige µ-opioide subreseptorer?
  • Haugen, Karianne Slåtta; Ripel, Åse & Andersen, Jannike Mørch (2011). Påvirker etanol metabolismen av heroin?
  • Andersen, Jannike Mørch; Olaussen, Christine Fostveit; Ripel, Åse & Mørland, Jørg (2011). Langvarig metadonbehandling svekker kognitiv funksjonsevne hos rotter.
  • Sankararaman, Aparna; Richardson, Devon; Andersen, Jannike Mørch; Mørland, Jørg & Eisch, Amelia (2011). Effect of methadone on neurogenesis in rats.
  • Andersen, Jannike Mørch; Ripel, Åse; Boix, Fernando; Normann, Per Trygve & Mørland, Jørg (2011). Glem heroin og morfin! - Det er 6MAM som medierer den umiddelbare heroinresponsen.
  • Boix, Fernando; Andersen, Jannike Mørch & Mørland, Jørg (2011). Heroin: det er 6-MAM som ”går rett i hodet”.
  • Boix, Fernando; Andersen, Jannike Mørch & Mørland, Jørg (2010). Farmakokinetikk av heroin i blod og hjerne i mus.
  • Andersen, Jannike Mørch; Ripel, Åse; Boix, Fernando; Normann, Per Trygve & Mørland, Jørg (2010). Glem morfin! – 6-monoacetylmorfin medierer den umiddelbare heroinresponsen.
  • Andersen, Jannike Mørch; Ripel, Åse; Boix, Fernando; Normann, Per Trygve & Mørland, Jørg (2009). The acute behavioural response to heroin in mice is mediated by the initial metabolite 6-acetylmorphine and not morphine.
  • Olaussen, Christine Fostveit; Lieng, Nina; Normann, Per Trygve & Andersen, Jannike Mørch (2009). Påvirker metadon kognitive funksjoner hos rotte?
  • Andersen, Jannike Mørch (2008). Påvirker metadon kognitive funksjoner?
  • Willoch, Frode; Lobmaier, Philipp Paul; Kunøe, Nikolaj; Waal, Helge; Andersen, Jannike Mørch & Sundet, Kjetil Søren [Show all 7 contributors for this article] (2008). ”Kognitiv evne og nevrobiologiske prosesser hos heroinavhengige i behandling”.
  • Ripel, Åse; Hasvold, Inger; Karinen, Ritva Anneli; Andersen, Jannike Mørch & Christophersen, Asbjørg S. (2008). Determination of heroin and the metabolites in blood by LC-MS/MS.
  • Andersen, Jannike Mørch; Billington, Camilla & Normann, Per Trygve (2007). Hvorfor er heroin et mye mer potent rusmiddel sammenliknet med morfin?
  • Andersen, Jannike Mørch; Boix, Fernando; Billington, Camilla; Normann, Per Trygve & Mørland, Jørg (2007). Heroin, 6MAM and morphine: locomotor activity and pharmacokinetic in mice.
  • Andersen, Jannike Mørch; Myhre, Oddvar; Vestad, Tor Arne; Aarnes, Halvor & Fonnum, Frode (2000). bA(25-35) produces free radicals in human neutrophil granulocytes. A study including fluorescence, electron paramagnetic resonance (EPR) spectroscopy and aromatic acid hydroxylation.
  • Andersen, Jannike Mørch & Olaussen, Christine Fostveit (2009). Does long-term methadone exposure affect cognitive functions in rats? Effects on novelty exploration and phosphorylation of CaMKII and ERK. University of Oslo.

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Published Sep. 25, 2017 10:57 AM - Last modified Aug. 15, 2019 10:18 AM

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