Professional interests
Preparation and physical characterization of formulations for drug delivery, with a special heart for nanoparticulate formulations like liposomal systems.
Characterization methods:
Dynamic Light Scattering (DLS), Electrophoretic Light Scattering (ELS), Differential Scanning Calorimetry (DSC), Texture Analysis, Rheology
Teaching:
Laboratory courses in preparation of powders, capsules and tablets - and preparation/characterization of nanoparticles.
Development and operation of the virtual learning environment for production and control of medicinal products.
Background
Statens reseptarhøgskole
Prescriptionist (Bachelor level pharmacist)
1989
University of Oslo
Individual topics: Biochemistry, Statistics, Physiology, Pharmacology, Pharmaceutics
1991-2007
Norges landbrukshøgskole (NMBU)
University pedagogy for engineers
2003
Appointments
- Member, The Department Board, Department of Pharmacy (2022-2024)
- Member, Promotion Committe, Department of Pharmacy (2008 - )
Publications
Teklu, Solomon; Gundersen, Lise-Lotte; Larsen, Tove; Malterud, Karl Egil; Rise, Frode. Indolizine 1-sulfonates as potent inhibitors of 15-lipoxygenase from soybeans. Bioorganic & Medicinal Chemistry 2005;13:3127-3139
Stensrud, G., Passi, S., Larsen, T., Sandset, P.M., Smistad, G., Mönkkönen, J., Karlsen, J., Toxicity of gamma irradiated liposomes. 1. In vitro interactions with blood components, Int. J. Pharm., 178 (1999) 33-46
Stensrud, G., Smistad, G., Ågren, T.L., Sande, S.A., Karlsen, J., Effects of gamma irradiation on the physical stability of liposomal phospholipids.. Journal of Liposome Research, 7 (1997) 503-528
Stensrud, G., Rantanen, L., Ågren, T.L., Smistad, G. and Karlsen, J., Effects of γ-irradiation on the phase transition behaviour of phospholipids as solids and liposomes, Progress in Drug Delivery System, V (1996) 9-12
Henriksen, I., Sande, S.A., Smistad, G., Ågren, T.L. and Karlsen, J., In vitro evaluation of drug release kinetics from liposomes by fractional dialysis, International Journal of Pharmaceutics, 119 (1995) 231-238
Bjåen, A-K., Nord, K., Furuseth, S., Ågren, T., Tønnesen, H.H. and Karlsen, J., Polymorphism of chloroquine diphosphate, International Journal of Pharmaceutics, 92 (1993) 183-189
Tønnesen, H.H., Smistad, G., Ågren, T. and Karlsen, J., Studies on curcumin and curcuminoids. XXIII: Effects of curcumin on liposomal lipid peroxidation, International Journal of Pharmaceutics, 90 (1993) 221-228
Smistad, G., Rolfsen, T., Ågren, T., Tønnesen, H.H., Roos, N. and Karlsen, J., Cryo-electron microscopy of fully-hydrated liposomes as a quality control method, Micron and Microscopica Acta, 22 (1991) 85-86