Publications

The list of publications includes selected publications related to the different research group's topics of interest. 

Hedvig Nordeng, Anteneh Desalegn, and Saeed Hayati headshots photo collages.

Photos: Private

Hedvig Nordeng's publications in PubMed

Anteneh Desalegn's Publications in PubMed

Saeed Hayati's Publications in PubMed

Selected publications

Medications in Pregnancy

  1. Meng LC, van Gelder MMHJ, Chuang HM, Lai HY, Chen LK, Hsiao FY, Nordeng HME. Valproate Use by Fathers and Risk of Neurodevelopmental Disorders in Children. NEJM Evid. 2026 Mar;5(3):EVIDoa2500254. doi: 10.1056/EVIDoa2500254. Epub 2026 Feb 24. PMID: 41733407.
  2. Reddy AS, Fawad F, Leite MA, Olstad EW, Gervin K, Kanduri C, Sandve GK, Brandlistuen R, Lupattelli A, von Koss Torkildsen J, Nordeng HME. Prenatal exposure to psychotropics and analgesics on cognitive, linguistic and educational outcomes - a scoping review with focus on validity and reliability of outcome measures. BMC Pregnancy Childbirth. 2025 Mar 3;25(1):234.
  3. Boissiere-O'Neill T, van Gelder MMHJ, Engjom HM, Nordeng HME. Exposure to systemic antimicrobials during pregnancy and risk of miscarriage: A population-based registry study. BJOG. 2025 Mar 28.
  4. Johnson H, Hjorth S, Morris J, Pottegård A, Leinonen M, Norby U, Nordeng H. Use of signal detection methods to identify associations between prenatal medication exposure and subsequent childhood cancers: a Nordic hypothesis-generating registry-based study. Expert Opin Drug Saf. 2025 Feb 12:1-12.
  5. Meng LC, van Gelder MMHJ, Chuang HM, Chen LK, Hsiao FY, Nordeng HME. Paternal metformin use and risk of congenital malformations in offspring in Norway and Taiwan: population-based, cross-national cohort study. BMJ. 2024 Oct 16;387:e080127. doi: 10.1136/bmj-2024-080127. PMID: 39414354; PMCID: PMC11480814.
  6. Harris GM, Wood M, Ystrom E, Nordeng H. Association of Maternal Use of Triptans During Pregnancy With Risk of Attention-Deficit/Hyperactivity Disorder in Offspring. JAMA Netw Open. 2022 Jun 1;5(6):e2215333. doi: 10.1001/jamanetworkopen.2022.15333.
  7. Hjorth S, Pottegård A, Broe A, Hemmingsen CH, Leinonen MK, Hargreave M, Nörby U, Nordeng H. Prenatal exposure to nitrofurantoin and risk of childhood leukaemia: a registry-based cohort study in four Nordic countries. Int J Epidemiol. 2022 Jun 13;51(3):778-788. doi: 10.1093/ije/dyab219.
  8. Lupattelli A, Barone-Adesi F, Nordeng H. Association between antidepressant use in pregnancy and gestational diabetes mellitus: Results from the Norwegian Mother, Father and Child Cohort Study. Pharmacoepidemiol Drug Saf. 2022 Feb;31(2):247-256. doi: 10.1002/pds.5388. Epub 2021 Dec 8.
  9. Trinh NTH, Nordeng H, Bandoli G, Eberhard-Gran M, Lupattelli A. Antidepressant and mental health care utilization in pregnant women with depression and/or anxiety: An interrupted time-series analysis. J Affect Disord. 2022 Jul 1;308:458-465. doi: 10.1016/j.jad.2022.04.101. Epub 2022 Apr 21.
  10. Trønnes JN, Lupattelli A, Ystrom E, Nordeng H. Analysis of Prenatal Exposure to Opioid Analgesics and Scholastic Skills in Children in Fifth Grade in Norway. JAMA Netw Open. 2022 Jul 1;5(7):e2222425. doi: 10.1001/jamanetworkopen.2022.22425.
  11. Morales DR, Fonkwen L, Nordeng H. Antithyroid drug use during pregnancy and the risk of birth defects in offspring: systematic review and meta-analysis of observational studies with methodological considerations. Br J Clin Pharmacol. 2021 Oct;87(10):3890-3900. doi: 10.1111/bcp.14805. Epub 2021 Mar 30.
  12. Lupattelli A, Mahic M, Handal M, Ystrom E, Reichborn-Kjennerud T, Nordeng H. Attention-deficit/hyperactivity disorder in children following prenatal exposure to antidepressants: results from the Norwegian mother, father and child cohort study. BJOG. 2021 Nov;128(12):1917-1927. doi: 10.1111/1471-0528.16743. Epub 2021 Jun 8.
  13. Grzeskowiak LE, Saha MR, Ingman WV, Nordeng H, Ystrom E, Amir LH. Incidence, antibiotic treatment and outcomes of lactational mastitis: Findings from The Norwegian Mother, Father and Child Cohort Study (MoBa). Paediatr Perinat Epidemiol. 2022 Mar;36(2):254-263. doi: 10.1111/ppe.12824. Epub 2021 Nov 28.
  14. Hjorth S, Hemmingsen CH, Bénévent J, Broe A, Pottegaard A, Mørch LS, Leinonen MK, Kjaer SK, Hargreave M, Nordeng H. Maternal Medication Use and Childhood Cancer in Offspring-Systematic Review and Considerations for Researchers. Am J Epidemiol. 2021 Nov 2;190(11):2487-2499. doi: 10.1093/aje/kwab154.
  15. van Gelder MMHJ, Nordeng H. Antiemetic Prescription Fills in Pregnancy: A Drug Utilization Study Among 762,437 Pregnancies in Norway. Clin Epidemiol. 2021 Feb 26;13:161-174. doi: 10.2147/CLEP.S287892.
  16. Hjorth S, Wood M, Tauqeer F, Nordeng H. Fertility treatment and oral contraceptive discontinuation for identification of pregnancy planning in routinely collected health data - an application to analgesic and antibiotic utilisation. BMC Pregnancy Childbirth. 2020 Nov 25;20(1):731. doi:10.1186/s12884-020-03435-4.
  17. Lupattelli A, Wood M, Ystrom E, Skurtveit S, Handal M, Nordeng H. Effect of Time-Dependent Selective Serotonin Reuptake Inhibitor Antidepressants During Pregnancy on Behavioral, Emotional, and Social Development in Preschool-Aged Children. J Am Acad Child Adolesc Psychiatry. 2018 Mar;57(3):200-208. doi: 10.1016/j.jaac.2017.12.010. Epub 2017 Dec 28.
  18. Ahmed SM, Sundby J, Aragaw YA, Nordeng H. Medication-related problems among hospitalized pregnant women in a tertiary teaching hospital in Ethiopia: a prospective observational study. BMC Pregnancy Childbirth. 2020 Nov 26;20(1):737. doi: 10.1186/s12884-020-03433-6.BMJ Open. 2018 Jan 23;8(1):e020106. doi: 10.1136/bmjopen-2017-020106.
  19. Smedberg J, Bråthen M, Waka MS, Jacobsen AF, Gjerdalen G, Nordeng H. Medication use and drug-related problems among women at maternity wards-a cross-sectional study from two Norwegian hospitals. Eur J Clin Pharmacol. 2016 Jul;72(7):849-57. doi: 10.1007/s00228-016-2042-0. Epub 2016 Mar 29.

Breast Milk Studies

  1. Baklouti S, Rigourd V, Panchaud A, Nordeng H, Allegaert K, Annaert P, Huang MC, Monfort A, Guidi M, Gandia P. Population pharmacokinetic modelling of amoxicillin in human breast milk-A contribution from the ConcePTION project. Br J Clin Pharmacol. 2026 Jan 25. doi: 10.1002/bcp.70434. Epub ahead of print. PMID: 41582095.
  2. Macente J, Nauwelaerts N, Badée JM, Bonan RH, Huang MC, Van Neste M, Smits A, Allegaert K, Nordeng H, Hovd M, Martins FS, Annaert P. Predicting Drug Transfer Into Human Milk With the Simcyp Simulator: A Contribution From the ConcePTION Project. CPT Pharmacometrics Syst Pharmacol. 2025 Jul 9. doi: 10.1002/psp4.70066. Epub ahead of print. PMID: 40632507.
  3. Liu X, Madsen KB, Zhu JL, Munk-Olsen T, Damkier P, Lupattelli A, Zoega H, Nordeng H, Kjeldsen MZ, Mægbæk ML, Madsen MG, Bergink V, Bliddal M. Psychotropic Medication Exposure via Breast Milk: A Population-Based Descriptive Study in Denmark. Paediatr Perinat Epidemiol. 2025 Sep 11. doi: 10.1111/ppe.70074. Epub ahead of print. PMID: 40931951.

Methods

  1. Zugic M, Pejic N, Hayati S, van Gelder MMHJ, Nordeng H. Development of a novel adherence scale for antidepressants in pregnancy: Results from a cross-sectional study. Explor Res Clin Soc Pharm. 2026 Jan 12;21:100704. doi: 10.1016/j.rcsop.2026.100704. PMID: 41694802; PMCID: PMC12905790.
  2. Sakai T, Nordeng H, van Gelder MMHJ. Response to: Is the Most Likely Value Also the Best Imputation? Paediatr Perinat Epidemiol. 2026 Feb 3. doi: 10.1111/ppe.70119. Epub ahead of print. PMID: 41635002.
  3. Olstad EW, Nordeng H, Bjørk MH, Selmer KK, Gervin K. Agreement Between Parental Self-Reported Antiseizure Medication Use and Dispensed Prescription Records From a National Prescription Database. Pharmacoepidemiol Drug Saf. 2025 Apr;34(4):e70139.
  4. Wood M, Lupattelli A, Palmsten K, Bandoli G, Hurault-Delarue C, Damase-Michel C, Chambers CD, Nordeng H, van Gelder MMHJ. Longitudinal Methods for Modeling Exposures in Pharmacoepidemiologic Studies in Pregnancy. Epidemiol Rev. 2022 Jan 14;43(1):130-146. doi: 10.1093/epirev/mxab002.
  5. Wood M, Lapane KL, van Gelder MMHJ, Rai D, Nordeng H. Making fair comparisons in pregnancy medication safety studies: An overview of advanced methods for confounding control. Pharmacoepidemiol Drug Saf. 2018 Feb;27(2):140-147. doi: 10.1002/pds.4336. Epub 2017 Oct 17

Vaccines

  1. Zidan M, Trinh NTH, Desalegn A, Smith LH, van Gelder MMHJ, Nordeng H, Lupattelli A. BNT162b2 mRNA COVID-19 vaccine effectiveness in pregnancy: Emulating trial NCT04754594 using observational data from Norwegian health registries. Vaccine. 2025 Nov 6;68:127908. doi: 10.1016/j.vaccine.2025.127908. Epub ahead of print. PMID: 41202612.
  2. Català M, Mercadé-Besora N, Kolde R, Trinh NTH, Roel E, Burn E, Rathod-Mistry T, Kostka K, Man WY, Delmestri A, Nordeng HME, Uusküla A, Duarte-Salles T, Prieto-Alhambra D, Jödicke AM. The effectiveness of COVID-19 vaccines to prevent long COVID symptoms: staggered cohort study of data from the UK, Spain, and Estonia. Lancet Respir Med. 2024 Jan 11:S2213-2600(23)00414-9. doi: 10.1016/S2213-2600(23)00414-9. Epub ahead of print. PMID: 38219763.
  3. Trinh NT, Jödicke AM, Català M, Mercadé-Besora N, Hayati S, Lupattelli A, Prieto-Alhambra D, Nordeng HM. Effectiveness of COVID-19 vaccines to prevent long COVID: data from Norway. Lancet Respir Med. 2024 Apr 10:S2213-2600(24)00082-1. doi: 10.1016/S2213-2600(24)00082-1. Epub ahead of print. PMID: 38614106.
  4. Moreno-Martos D, Zhao J, Li H, Nyberg F, Bjørndal LD, Hajiebrahimi M, Wettermark B, Aakjær M, Andersen M, Sessa M, Lupattelli A, Nordeng H, Morales DR. Impact of the early COVID-19 pandemic on adult mental health-related dispensed medications, hospitalizations and specialist outpatient visits in Norway and Sweden: Interrupted time series analysis. Br J Clin Pharmacol. 2024 Mar 31. doi: 10.1111/bcp.16044. Epub ahead of print. PMID: 38555909.
  5. Hurley E, Geisler BP, Lupattelli A, Poblador-Plou B, Lassalle R, Jové J, Bernard MA, Sakr D, Sanfélix-Gimeno G, Sánchez-Saez F, Rodríguez-Bernal CL, Sabaté M, Ballarín E, Aguilera C, Jordan S, Thayer D, Farr I, Ahmed S, Bartolini C, Limoncella G, Paoletti O, Gini R, Maglanoc LA, Dudukina E, Ehrenstein V, Alsina E, Vaz TA, Riera-Arnau J, Sturkenboom MCJM, Nordeng HME. COVID-19 and pregnancy: A European study on pre- and post-infection medication use. Eur J Clin Pharmacol. 2024 Feb 12. doi: 10.1007/s00228-024-03639-z. Online ahead of print. PMID: 38347228
  6. Pedersen E, Tripodi E, Aakjaer M, Li H, Cantarutti A, Nyberg F, Andersen M, Lupattelli A, Nordeng H. Drug utilisation in children and adolescents before and after the start of the COVID-19 pandemic: Interrupted time-series analyses in three European countries. Paediatr Perinat Epidemiol. 2024 Feb 1. doi: 10.1111/ppe.13046. Online ahead of print. PMID: 38299727
  7. Shakibfar S, Zhao J, Li H, Nordeng H, Lupattelli A, Pavlovic M, Sandve GK, Nyberg F, Wettermark B, Hajiebrahimi M, Andersen M, Sessa M. Machine learning-driven development of a disease risk score for COVID-19 hospitalization and mortality: a Swedish and Norwegian register-based study. Front Public Health. 2023 Dec 7;11:1258840. doi: 10.3389/fpubh.2023.1258840. eCollection 2023. PMID: 38146473
  8. Shakibfar S, Zhao J, Li H, Nordeng H, Lupattelli A, Pavlovic M, Sandve GK, Nyberg F, Wettermark B, Hajiebrahimi M, Andersen M, Sessa M. Machine learning-driven development of a disease risk score for COVID-19 hospitalization and mortality: a Swedish and Norwegian register-based study. Front Public Health. 2023 Dec 7;11:1258840. doi: 10.3389/fpubh.2023.1258840. eCollection 2023. PMID: 38146473
  9. Tauqeer F, Ceulemans M, Gerbier E, Passier A, Oliver A, Foulon V, Panchaud A, Lupattelli A, Nordeng H. Mental health of pregnant and postpartum women during the third wave of the COVID-19 pandemic: a European cross-sectional study. BMJ Open. 2023 Jan 11;13(1):e063391. doi: 10.1136/bmjopen-2022-063391. PMID: 36631239
  10. Ceulemans M, Foulon V, Ngo E, Panchaud A, Winterfeld U, Pomar L, Lambelet V, Cleary B, O'Shaughnessy F, Passier A, Richardson JL, Hompes T, Nordeng H. Mental health status of pregnant and breastfeeding women during the COVID-19 pandemic-A multinational cross-sectional study. Acta Obstet Gynecol Scand. 2021 Jul;100(7):1219-1229. doi: 10.1111/aogs.14092. Epub 2021 Feb 13.
  11. Ceulemans M, Foulon V, Panchaud A, Winterfeld U, Pomar L, Lambelet V, Cleary B, O'Shaughnessy F, Passier A, Richardson JL, Nordeng H. Self-Reported Medication Use among Pregnant and Breastfeeding Women during the COVID-19 Pandemic: A Cross-Sectional Study in Five European Countries. Int J Environ Res Public Health. 2022 Jan 26;19(3):1389. doi: 10.3390/ijerph19031389.

Pharmaco(epi)genetics

  1. Carson AC, Zidan M, Olstad EW, Gervin K, Galesloot TE, Scholte I, Ystrøm E, Nordeng H, van Gelder MMHJ. Genetically Informed Research Designs in Perinatal Pharmacoepidemiology: A Methodological Overview. Drug Saf. 2026 Mar 2. doi: 10.1007/s40264-026-01647-9. Epub ahead of print. PMID: 41770489.
  2. Olstad EW, Nordeng HME, Bjørk MH, Selmer K, Gervin K. Paternal valproate use and impact of shared genetic susceptibility on child neurodevelopment. Sci Rep. 2025 Nov 7;15(1):39033. doi: 10.1038/s41598-025-23377-1. PMID: 41203668; PMCID: PMC12595016.
  3. Gomes JDA, Olstad EW, Kowalski TW, Gervin K, Vianna FSL, Schüler-Faccini L, Nordeng H. Genetic Susceptibility to Drug Teratogenicity: A Systematic Literature Review. Front Genet. 2021 Apr 27;12:645555. doi: 10.3389/fgene.2021.645555. PMID: 33981330; PMCID: PMC8107476.
  4. Olstad EW, Nordeng HME, Gervin K. Prenatal medication exposure and epigenetic outcomes: a systematic literature review and recommendations for prenatal pharmacoepigenetic studies. Epigenetics. 2021 Apr 29:1-24. doi: 10.1080/15592294.2021.
  5. Olstad EW, Nordeng HME, Lyle R, Gervin K. No impact of prenatal paracetamol and folic acid exposure on cord blood DNA methylation in children with attention-deficit/hyperactivity disorder. Front Genet. 2023 Jun 15;14:1204879. doi: 10.3389/fgene.2023.1204879. PMID: 37396039; PMCID: PMC10310527.
  6. Olstad EW, Nordeng HME, Sandve GK, Lyle R, Gervin K. Effects of prenatal exposure to (es)citalopram and maternal depression during pregnancy on DNA methylation and child neurodevelopment. Transl Psychiatry. 2023 May 5;13(1):149. doi: 10.1038/s41398-023-02441-2. PMID: 37147306; PMCID: PMC10163054.
  7. Olstad EW, Nordeng HME, Sandve GK, Lyle R, Gervin K. Low reliability of DNA methylation across Illumina Infinium platforms in cord blood: implications for replication studies and meta-analyses of prenatal exposures. Clin Epigenetics. 2022 Jun 28;14(1):80. doi: 10.1186/s13148-022-01299-3. PMID: 35765087; PMCID: PMC9238140.

 

Text books

  1. Nilssen LS, Nordeng H. G7. Graviditet og legemidler. In: Pilskog S, ed. Norsk legemiddelhåndbok. Pilskog S (red). Norsk legemiddelhåndbok; 2022.
  2. Nordeng H, Nilssen LS. G8. Amming og legemidler. In: Pilskog S, ed. Norsk Legemiddelhåndbok. Pilskog S (red). Norsk legemiddelhåndbok; 2022.
  3. Nordeng H, Spigset O. Legemidler og bruken av dem. 3rd ed. Gyldendal Akademiske; 2018.
Published Oct. 24, 2013 10:57 AM - Last modified June 19, 2026 3:31 PM
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