Determination of amphetamine enantiomers in urine by conductive vial electromembrane

Amphetamines are commonly used for managing ADHD and narcolepsy, but are unfortunately also the most common drugs of abuse world-wide. During synthesis, a racemic mixture is produced, where in illicit preparations, both enantiomers are present, while the most pharmacologically active enantiomer is isolated in medicinal products. This creates an avenue for identifying recreational users through the detection of both enantiomers in urine. In this work, a validated EME method was developed for the extraction of both amphetamine enantiomers and compared to the routine method used at St. Olav University Hospital. This paper is an engaging read for both newcomers and experienced EME users.

Click here to read the article...