HEALTHx2: patient-centered approaches for studying the effectiveness and reproductive safety of antidepressant medication in perinatal women
The HEALTHx2 project aims to generating and disseminating evidence about the effectiveness and reproductive safety of antidepressant medication in pregnancy and after childbirth. Involvement of patient stakeholders is central in the project.
Currently, we are additionally conducting a mixed-method study to understand women’s decisional conflicts about antidepressant treatment in the perinatal period. This is an important knowledge gap to fill in order to support shared decision-making on antidepressant treatment in pregnant and breastfeeding women.
Participation in the study involves filling out an electronic questionnaire (access via ID-porten) and for some women, a focus group interview later in 2020. The project is now seeking participants to address this latter research question, as outline in the figure below. Pregnant women, women who gave birth in the last 5 years, and women planning a pregnancy, can participate. Women must have been offered treatment with an antidepressant in the last 5 years to be eligible.
Delta i HEALTHx2 studie
The project will provide the evidence base for important clinical decisions: whether to treat a perinatal psychiatric disorder or no. It will also facilitate women empowerment in developing an evidence-based understanding of the benefits and risks of perinatal use of antidepressants.
Publications
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Ilic, Miljana; Nordeng, Hedvig Marie Egeland & Lupattelli, Angela (2021). Medical care contact for infertility and related medication use during pregnancy – a European, cross-sectional web-based study. Norsk Epidemiologi. ISSN 0803-2491. 29(1-2), p. 97–106. doi: 10.5324/nje.v29i1-2.4051. Full text in Research Archive
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Tauqeer, Fatima; Wood, Mollie; Andersen, Sarah Hjorth; Lupattelli, Angela & Nordeng, Hedvig (2021). Perinatal use of triptans and other drugs for migraine - A nationwide drug utilization study. PLOS ONE. ISSN 1932-6203. 16(8). doi: 10.1371/journal.pone.0256214. Full text in Research Archive
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Wood, Mollie; Lupattelli, Angela; Palmsten, Kristin; Bandoli, Gretchen; Hurault-Delarue, Caroline & Damase-Michel, Christine [Show all 9 contributors for this article] (2021). Longitudinal Methods for Modeling Exposures in Pharmacoepidemiologic Studies in Pregnancy. Epidemiologic Reviews. ISSN 0193-936X. 43(1), p. 130–146. doi: 10.1093/epirev/mxab002. Full text in Research Archive
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Gustavson, Kristin; Ystrøm, Eivind; Ask, Helga; Torvik, Fartein Ask; Hornig, Mady & Susser, Ezra [Show all 16 contributors for this article] (2021). Acetaminophen use during pregnancy and offspring attention deficit hyperactivity disorder - a longitudinal sibling control study. JCPP Advances. ISSN 2692-9384. 1(2). doi: 10.1002/jcv2.12020. Full text in Research Archive
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Vallee, Jennifer; Wong, Yih; Mannino, Eline; Nordeng, Hedvig Marie Egeland & Lupattelli, Angela (2020). Association between Antidepressant Treatment during Pregnancy and Postpartum Self-Harm Ideation in Women with Psychiatric Disorders: A Cross-Sectional, Multinational Study. International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. 18(1), p. 1–15. doi: 10.3390/ijerph18010046. Full text in Research Archive
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Lupattelli, Angela & Nordeng, Hedvig Marie Egeland (2021). Does antidepressant use in pregnancy increase the risk of ADHD in children? BestPractice nordic.
Published Apr. 27, 2020 10:32 AM
- Last modified Sep. 26, 2020 4:14 PM
