Kjetill Sigurd Jakobsen

Image of Kjetill Sigurd Jakobsen
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Phone +47-22854602
Mobile phone +47-90741779
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Visiting address Blindernveien 31 None 0371 OSLO
Postal address Postboks 1066 Blindern 0316 OSLO

Centre for Ecological and Evolutionary Synthesis (CEES)

I have been the Chair of CEES since the end of September 2018. (CEES News)

The Norwegian Sequencing Centre

I founded (in 2009) the Norwegian Sequencing Centre (NSC) – a national high throughput sequencing infrastructure.

Research interests

My research has dealt with quite diverse aspects of evolutionary genetics and genomics. A main theme in my work relates to the genetic forces (both ongoing and historical) acting upon populations, and how the genetics relates to ecological and evolutionary processes. In this context, issues such as phenotypic plasticity, selective forces and epigenetic phenomena are of particular interest.

Essential ingredients in my interdisciplinary approach are genomics, bioinformatics, statistics and phylogeny, combined with evolutionary and ecological thinking. Through this, I aim to contribute to bridging the gap between organism-oriented research (evolutionary and ecological research), and genomics/molecular biology (phenotype-genotype issues).

Biological systems

I have worked on many biological systems ranging from cyanobacteria and protists to higher plants, fishes and mammals. Currently my research group focuses on bacteria – particularly cyanobacteria – and several protist and algal groups. The protist research is driven by a wish to understand the processes shaping such “alien” genomes –including endosymbiosis, gene transfer and protistt phylogenomics. From a large-scale phylogenetic viewpoint Dinoflagellates, Chromista, Rhizaria and some groups of deep branching unikont protists are my favorites. Another favorite group – Cyanobacteria being the key organisms in evolution of many protist groups and the most successful group of organisms throughout the evolutionary history – are being investigated at the comparative genome level and for their non-ribosomal peptide syntethases.

Endosymbiosis, eukaryotic supergroups, evolution of multicellularity, horizontal gene transfer in eukaryotes, and reticulate evolution in plants

My colleagues and I have made significant contributions to endosymbiosis (Tengs et al. MBE 2000; Shalchian-Tabrizi et al. MBE 2006), eukaryotic supergroups (Burki et al. PLoS ONE 2007), evolution of multicellularity (Shalchian-Tabrizi et al. PLoS ONE 2008; Minge PRSB 2009), horizontal gene transfer in eukaryotes (Stüken et al. PLoS ONE 2011) and reticulate evolution in plants (Marcussen et al. Syst Biol 2012, 2014; Marcussen et al. Science 2014).

Sequencing of the Atlantic cod and the evolution of the immune system

A major achievement has been the sequencing of the Atlantic cod (Gadus morhua) genome and the implications for our understanding of the vertebrate immune system. (Star et al. Nature 2011).

The evolution of the immune system in codfishes and other teleosts has been further investigated by experimental approaches and by complete genome sequencing of more than 100 species – and the results suggest that immunological innovation is correlated with high speciation rates (Malmstrøm et al. Nature Genetics 2016, and  Solbakken et al.  Proceedings of the Royal Society B 2017). Further, population genomics of Atlantic cod and salmon is studied in a large project funded with 40 MNOK from the Research Council of Norway (RCN) by whole genome sequencing of thousands of individuals. The results from Atlantic cod have so far revealed a highly unusual sex locus (Star et al. Scientific Reports 2016) that the genomic divergence between stationary and migratory cod is caused by a few large non-recombining genomic regions (Berg et al. Scientific Reports 2016, 2017, Star et al. PNAS 2017).

Tags: Life sciences

Publications

  • Eide, Marta; Rydbeck, Halfdan; Tørresen, Ole K.; Lille-Langøy, Roger; Puntervoll, Pål; Goldstone, Jared V.; Jakobsen, Kjetill Sigurd; Stegeman, John; Goksøyr, Anders & Karlsen, Odd Andre (2018). Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports.  ISSN 2045-2322.  8, s 1- 13 . doi: 10.1038/s41598-018-28498-4 Full text in Research Archive.
  • Hoff, Siv Nam Khang; Baalsrud, Helle Tessand; Tooming-Klunderud, Ave; Skage, Morten; Richmond, Todd; Obernosterer, Gregor; Shirzadi, Reza; Tørresen, Ole K.; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2018). Long‐read sequence capture of the haemoglobin gene clusters across codfish species. Molecular Ecology Resources.  ISSN 1755-098X. . doi: 10.1111/1755-0998.12955
  • Jørgensen, Tor Erik; Karlsen, Bård Ove; Emblem, Åse; Breines, Ragna; Andreassen, morten; Rounge, Trine Ballestad; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd; Nymark, Marianne; Ursvik, anita; Coucheron, Dag H; Jakt, Lars Martin; Nordeide, Jarle Tryti; Moum, Truls Borg & Johansen, Steinar Daae (2018). Mitochondrial genome variation of Atlantic cod. BMC Research Notes.  ISSN 1756-0500.  11:397, s 1- 7 . doi: 10.1186/s13104-018-3506-3 Full text in Research Archive.
  • Malmstrøm, Martin; Britz, Ralf; Matschiner, Michael; Tørresen, Ole K.; Hadiaty, Renny Kurnia; Yaakob, Norsham; Tan, Heok Hui; Jakobsen, Kjetill Sigurd; Salzburger, Walter & Rüber, Lukas (2018). The Most Developmentally Truncated Fishes Show Extensive Hox Gene Loss and Miniaturized Genomes. Genome Biology and Evolution.  ISSN 1759-6653.  10(4), s 1088- 1103 . doi: 10.1093/gbe/evy058
  • Riiser, Even Sannes; Haverkamp, Thomas Hendricus Augustus; Borgan, Ørnulf; Jakobsen, Kjetill Sigurd; Jentoft, Sissel & Star, Bastiaan (2018). A single vibrionales 16S rRNA oligotype dominates the intestinal microbiome in two geographically separated Atlantic cod populations. Frontiers in Microbiology.  ISSN 1664-302X.  9 . doi: 10.3389/fmicb.2018.01561
  • Tørresen, Ole K.; Brieuc, Marine Servane; Solbakken, Monica Hongrø; Sørhus, Elin; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd; Meier, Sonnich; Edvardsen, Rolf & Jentoft, Sissel (2018). Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats. BMC Genomics.  ISSN 1471-2164.  19(240), s 1- 17 . doi: 10.1186/s12864-018-4616-y Full text in Research Archive.
  • Vader, Anna; Laughinghouse IV, Haywood; Griffiths, Colin; Jakobsen, Kjetill Sigurd & Gabrielsen, Tove M. (2018). Proton-pumping rhodopsins are abundantly expressed by microbial eukaryotes in a high-Arctic fjord. Environmental Microbiology.  ISSN 1462-2912.  20(2), s 890- 902 . doi: 10.1111/1462-2920.14035
  • Varadharajan, Srinidhi; Sandve, Simen Rød; Gillard, Gareth Benjamin; Tørresen, Ole K.; Mulugeta, Teshome Dagne; Hvidsten, Torgeir Rhoden; Lien, Sigbjørn; Vøllestad, Leif Asbjørn; Jentoft, Sissel; Nederbragt, Alexander Johan & Jakobsen, Kjetill Sigurd (2018). The grayling genome reveals selection on gene expression regulation after whole-genome duplication. Genome Biology and Evolution.  ISSN 1759-6653.  10(10), s 2785- 2800 . doi: 10.1093/gbe/evy201
  • Baalsrud, Helle Tessand; Tørresen, Ole Kristian; Solbakken, Monica Hongrø; Salzburger, Walter; Hanel, Reinhold; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2017). De novo gene evolution of antifreeze glycoproteins in codfishes revealed by whole genome sequence data. Molecular biology and evolution.  ISSN 0737-4038.  35(3), s 593- 606 . doi: 10.1093/molbev/msx311
  • Baalsrud, Helle Tessand; Voje, Kjetil L.; Tørresen, Ole Kristian; Solbakken, Monica Hongrø; Matschiner, Michael; Malmstrøm, Martin; Hanel, Reinhold; Salzburger, Walter; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2017). Evolution of Hemoglobin Genes in Codfishes Influenced by Ocean Depth. Scientific Reports.  ISSN 2045-2322.  7, s 1- 10 . doi: doi:10.1038/s41598-017-08286-2 Full text in Research Archive. Show summary
  • Barth, Julia Maria Isis; Berg, Paul Ragnar; Jonsson, Per R; Bonanomi, Sara; Corell, Hanna; Hemmer-Hansen, Jakob; Jakobsen, Kjetill Sigurd; Johannesson, Kerstin; Jorde, Per Erik; Knutsen, Halvor; Moksnes, Per-Olav; Star, Bastiaan; Stenseth, Nils Christian; Svedang, Henrik; Jentoft, Sissel & Andre, Carl (2017). Genome architecture enables local adaptation of Atlantic cod despite high connectivity. Molecular Ecology.  ISSN 0962-1083.  26(17), s 4452- 4466 . doi: 10.1111/mec.14207 Full text in Research Archive.
  • Berg, Paul Ragnar; Star, Bastiaan; Pampoulie, Christophe; Bradbury, Ian R.; Bentzen, Paul; Hutchings, Jeffrey; Jentoft, Sissel & Jakobsen, Kjetill Sigurd (2017). Trans-oceanic genomic divergence of Atlantic cod ecotypes is associated with large inversions. Heredity.  ISSN 0018-067X.  119, s 418- 428 . doi: 10.1038/hdy.2017.54 Full text in Research Archive.
  • Malmstrøm, Martin; Matschiner, Michael; Tørresen, Ole Kristian; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2017). Whole genome sequencing data and de novo draft assemblies for 66 teleost species. Scientific Data.  ISSN 2052-4463.  4, s 1- 13 . doi: 10.1038/sdata.2016.132 Full text in Research Archive.
  • Solbakken, Monica Hongrø; Voje, Kjetil L.; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2017). Linking species habitat and past palaeoclimatic events to evolution of the teleost innate immune system. Proceedings of the Royal Society of London. Biological Sciences.  ISSN 0962-8452.  284(1853), s 1- 9 . doi: 10.1098/rspb.2016.2810 Full text in Research Archive. Show summary
  • Star, Bastiaan; Boessenkool, Sanne; Gondek, Agata Teresa; Nikulina, Elena A.; Hufthammer, Anne Karin; Pampoulie, Christophe; Knutsen, Halvor; André, Carl; Nistelberger, Heidi Maria; Dierking, Jan; Petereit, Christoph; Heinrich, Dirk; Jakobsen, Kjetill Sigurd; Stenseth, Nils Christian; Jentoft, Sissel & Barrett, James H. (2017). Ancient DNA reveals the Arctic origin of Viking Age cod from Haithabu, Germany. Proceedings of the National Academy of Sciences of the United States of America.  ISSN 0027-8424.  114(34), s 9152- 9157 . doi: 10.1073/pnas.1710186114 Full text in Research Archive.
  • Tørresen, Ole Kristian; Star, Bastiaan; Jentoft, Sissel; Reinar, William Brynildsen; Grove, Harald; Miller, Jason R.; Walenz, Brian; Knight, James; Ekholm, Jenny M.; Peluso, Paul; Edvardsen, Rolf; Tooming-Klunderud, Ave; Skage, Morten; Lien, Sigbjørn; Jakobsen, Kjetill Sigurd & Nederbragt, Alexander Johan (2017). An improved genome assembly uncovers prolific tandem repeats in Atlantic cod. BMC Genomics.  ISSN 1471-2164.  18, s 1- 23 . doi: 10.1186/s12864-016-3448-x Full text in Research Archive.
  • Berg, Paul Ragnar; Star, Bastiaan; Pampoulie, Christophe; Sodeland, Marte; Barth, Julia Maria Isis; Knutsen, Halvor; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2016). Three chromosomal rearrangements promote genomic divergence between migratory and stationary ecotypes of Atlantic cod. Scientific Reports.  ISSN 2045-2322.  6, s 1- 12 . doi: 10.1038/srep23246 Full text in Research Archive.
  • Gante, Hugo F; Matschiner, Michael; Malmstrøm, Martin; Jakobsen, Kjetill Sigurd; Jentoft, Sissel & Salzburger, Walter (2016). Genomics of speciation and introgression in Princess cichlid fishes from Lake Tanganyika. Molecular Ecology.  ISSN 0962-1083.  25(24), s 6143- 6161 . doi: 10.1111/mec.13767 Show summary
  • Hicks, Natalie; Vik, Unni; Taylor, Peter; Ladoukakis, Efthymios; Park, Joonsang; Kolisis, Frangiskos & Jakobsen, Kjetill Sigurd (2016). Using Prokaryotes for Carbon Capture Storage. Trends in Biotechnology.  ISSN 0167-7799.  35(1), s 22- 32 . doi: 10.1016/j.tibtech.2016.06.011 Show summary
  • Lien, Sigbjørn; Koop, Ben F; Sandve, Simen Rød; Miller, Jason R.; Kent, Matthew Peter; Nome, Torfinn; Hvidsten, Torgeir Rhoden; Leong, Jong; Minkley, David R.; Zimin, Aleksey; Grammes, Fabian; Grove, Harald; Gjuvsland, Arne Bjørke; Walenz, Brian; Hermansen, Russell A.; von Schalburg, Kristian R.; Rondeau, Eric; Genova, Alex Di; Antony Samy, Jeevan Karloss; Vik, Jon Olav; Vigeland, Magnus Dehli; Caler, Lis; Grimholt, Unni; Jentoft, Sissel; Våge, Dag Inge; de Jong, Pieter J.; Moen, Thomas; Baranski, Matthew; Palti, Yniv; Smith, Douglas W.; Yorke, James A.; Nederbragt, Alexander J.; Tooming-Klunderud, Ave; Jakobsen, Kjetill Sigurd; Jiang, Xuanting; Fan, Dingding; Hu, Yan; Liberles, David A.; Vidal, Rodrigo; Iturra, Patricia; Jones, Steven J.M.; Jonassen, Inge; Maass, Alejandro; Omholt, Stig William & Davidson, William S (2016). The Atlantic salmon genome provides insights into rediploidization. Nature.  ISSN 0028-0836.  533(7602), s 200- 205 . doi: 10.1038/nature17164 Full text in Research Archive.
  • Malmstrøm, Martin; Matschiner, Michael; Tørresen, Ole Kristian; Star, Bastiaan; Snipen, Lars-Gustav; Hansen, Thomas F; Baalsrud, Helle Tessand; Nederbragt, Alexander Johan; Hanel, Reinhold; Salzburger, Walter; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2016). Evolution of the immune system influences speciation rates in teleost fishes. Nature Genetics.  ISSN 1061-4036.  48(10), s 1204- 1210 . doi: 10.1038/ng.3645 Full text in Research Archive.
  • Solbakken, Monica Hongrø; Rise, Matthew L.; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2016). Successive losses of central immune genes characterize the Gadiformes’ alternate immunity. Genome Biology and Evolution.  ISSN 1759-6653.  8(11), s 3508- 3515 . doi: 10.1093/gbe/evw250 Full text in Research Archive. Show summary
  • Solbakken, Monica Hongrø; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Seppola, Marit; Gregers, Tone Fredsvik; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2016). Evolutionary redesign of the Atlantic cod (Gadus morhua L.) Toll-like receptor repertoire by gene losses and expansions. Scientific Reports.  ISSN 2045-2322.  6 . doi: 10.1038/srep25211 Full text in Research Archive. Show summary
  • Star, Bastiaan; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd; Pampoulie, Christophe & Jentoft, Sissel (2016). Genomic characterization of the Atlantic cod sex-locus. Scientific Reports.  ISSN 2045-2322.  6, s 1- 9 . doi: 10.1038/srep31235 Full text in Research Archive.
  • Tørresen, Ole Kristian; Rise, Matthew L.; Jin, Xingkun; Star, Bastiaan; MacKenzie, Simon; Jakobsen, Kjetill Sigurd; Nederbragt, Alexander Johan & Jentoft, Sissel (2016). An improved version of the Atlantic cod genome and advancements in functional genomics: implications for the future of cod farming, In Simon MacKenzie & Sissel Jentoft (ed.),  Genomics in Aquaculture.  Elsevier.  ISBN 9780128014189.  3.  s 45 - 72
  • Tørresen, Ole Kristian; Star, Bastiaan; Jentoft, Sissel; Jakobsen, Kjetill Sigurd & Nederbragt, Alexander Johan (2016). The new era of genome sequencing using high-throughput sequencing technology: Generation of the first version of the Atlantic cod genome, In Simon MacKenzie & Sissel Jentoft (ed.),  Genomics in Aquaculture.  Elsevier.  ISBN 9780128014189.  1.  s 1 - 20
  • Berg, Paul Ragnar; Jentoft, Sissel; Star, Bastiaan; Ring, Kristoffer Hofaker; Knutsen, Halvor; Lien, Sigbjørn; Jakobsen, Kjetill Sigurd & Andre, Carl (2015). Adaptation to low salinity promotes genomic divergence in Atlantic Cod (Gadus morhua L.). Genome Biology and Evolution.  ISSN 1759-6653.  7(6), s 1644- 1663 . doi: 10.1093/gbe/evv093 Full text in Research Archive.
  • Marcussen, Thomas; Heier, Lise; Brysting, Anne Krag; Oxelman, Bengt & Jakobsen, Kjetill Sigurd (2015). From gene trees to a dated allopolyploid network: insights from the angiosperm genus Viola (Violaceae). Systematic Biology.  ISSN 1063-5157.  64(1), s 84- 101 . doi: 10.1093/sysbio/syu071
  • Sandve, Simen Rød; Marcussen, Thomas; Mayer, Klaus F X; Jakobsen, Kjetill Sigurd; Heier, Lise; Steuernagel, Burkhard; Wulff, Brande B.H. & Olsen, Odd-Arne (2015). Chloroplast phylogeny of Triticum/Aegilops species is not incongruent with an ancient homoploid hybrid origin of the ancestor of the bread wheat D-genome. New Phytologist.  ISSN 0028-646X.  208(1), s 9- 10 . doi: 10.1111/nph.13487
  • Stüken, Anke; Riobo, Pilar; Franco, Jose; Jakobsen, Kjetill Sigurd; Guillou, L & Figueroa, Rosa (2015). Paralytic shellfish toxin content is related to genomic sxtA4 copy number in Alexandrium minutum strains. Frontiers in Microbiology.  ISSN 1664-302X.  6, s 1- 10 . doi: 10.3389/fmicb.2015.00404 Full text in Research Archive.
  • Brembu, Tore; Winge, Per; Tooming-Klunderud, Ave; Nederbragt, Alexander Johan; Jakobsen, Kjetill Sigurd & Bones, Atle M. (2014). The chloroplast genome of the diatom Seminavis robusta: New features introduced through multiple mechanisms of horizontal gene transfer. Marine Genomics.  ISSN 1874-7787.  16(1), s 17- 27 . doi: 10.1016/j.margen.2013.12.002
  • Haverkamp, Thomas Hendricus Augustus; Hammer, Øyvind & Jakobsen, Kjetill Sigurd (2014). Linking geology and microbiology: Inactive pockmarks affect sediment microbial community structure. PLoS ONE.  ISSN 1932-6203.  9(1) . doi: 10.1371/journal.pone.0085990 Full text in Research Archive.
  • Keeling, Patrick J.; Burki, Fabien; Wilcox, Heather M.; Allam, Bassem; Allen, Eric E.; Amaral-Zettler, Linda A.; Armbrust, E. Virginia; Archibald, John M.; Bharti, Arvind K.; Bell, Callum J.; Beszteri, Bank; Bidle, Kay D; Cameron, Connor T; Campbell, Lisa; Caron, David A; Cattolico, Rose Ann; Collier, Jackie L; Coyne, Kathryn; Davy, Simon K; Deschamps, Phillipe; Dyhrman, Sonya T; Edvardsen, Bente; Gates, Ruth D; Gobler, Christopher J; Greenwood, Spencer J; Guida, Stephanie M; Jacobi, Jennifer L; Jakobsen, Kjetill Sigurd; James, Erick R; Jenkins, Bethany; John, Uwe; Johnson, Matthew D; Juhl, Andrew R; Kamp, Anja; Katz, Laura A; Kiene, Ronald; Kudryavtsev, Alexander; Leander, Brian S; Lin, Senjie; Lovejoy, Connie; Lynn, Denis; Marchetti, Adrian; McManus, George; Nedelcu, Aurora M; Menden-Deuer, Susanne; Miceli, Cristina; Mock, Thomas; Montresor, Marina; Moran, Mary Ann; Murray, Shauna; Nadathur, Govind; Nagai, Satoshi; Ngam, Peter B; Palenik, Brian; Pawlowski, Jan; Petroni, Giulio; Piganeau, Gwenael; Posewitz, Matthew C; Rengefors, Karin; Romano, Giovanna; Rumpho, Mary E; Rynearson, Tatiana; Schilling, Kelly B; Schroeder, Declan C; Simpson, Alastair G B; Slamovits, Claudio H; Smith, David R; Smith, G Jason; Smith, Sarah R; Sosik, Heidi M; Stief, Peter; Theriot, Edward; Twary, Scott N; Umale, Pooja E; Vaulot, Daniel; Wawrik, Boris; Wheeler, Glen L; Wilson, William H; Xu, Yan; Zingone, Adriana & Worden, Alexandra Z (2014). The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): Illuminating the Functional Diversity of Eukaryotic Life in the Oceans through Transcriptome Sequencing. PLoS biology.  ISSN 1544-9173.  12:e1001889(6) . doi: 10.1371/journal.pbio.1001889 Full text in Research Archive.
  • Marcussen, Thomas; Sandve, Simen Rød; Heier, Lise; Spannagl, Manuel; Pfeifer, Matthias; The International Wheat Genom, IWGSC; Jakobsen, Kjetill Sigurd; Wulff, Brande B.H.; Steuernagel, Burkhard; Mayer, Klaus & Olsen, Odd-Arne (2014). Ancient hybridizations among the ancestral genomes of bread wheat. Science.  ISSN 0036-8075.  345(6194) . doi: 10.1126/science.1250092
  • Siddiqui, Huma; Lagesen, Karin; Nederbragt, Alexander Johan; Eri, Lars Magne; Jeansson, Stig & Jakobsen, Kjetill Sigurd (2014). Pathogens in Urine from a Female Patient with Overactive Bladder Syndrome Detected by Culture-Independent High Throughput Sequencing: A Case Report. Open Microbiology Journal.  ISSN 1874-2858.  8, s 148- 153 . doi: 10.2174/1874285801408010148
  • Skog, Anna; Vøllestad, Leif Asbjørn; Stenseth, Nils Christian; Kasumyan, Alexander & Jakobsen, Kjetill Sigurd (2014). Circumpolar phylogeography of the northern pike (Esox lucius) and its relationship to the Amur pike (E. reichertii). Frontiers in Zoology.  ISSN 1742-9994.  11(67) . doi: 10.1186/s12983-014-0067-8 Full text in Research Archive.
  • Star, Bastiaan; Nederbragt, Alexander Johan; Hansen, Marianne Helén Selander; Skage, Morten; Gilfillan, Gregor Duncan; Bradbury, Ian R.; Pampoulie, Christophe; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2014). Palindromic sequence artifacts generated during next generation sequencing library preparation from historic and ancient DNA. PLoS ONE.  ISSN 1932-6203.  9(3) . doi: 10.1371/journal.pone.0089676 Full text in Research Archive.
  • Xiao, Xi; Sogge, Hanne; Lagesen, Karin; Tooming-Klunderud, Ave; Jakobsen, Kjetill Sigurd & Rohrlack, Thomas (2014). Use of high throughput sequencing and light microscopy show contrasting results in a study of phytoplankton occurrence in a freshwater environment. PLoS ONE.  ISSN 1932-6203.  9(8) . doi: 10.1371/journal.pone.0106510 Full text in Research Archive.
  • Frisli, Trine; Haverkamp, Thomas Hendricus Augustus; Jakobsen, Kjetill Sigurd; Stenseth, Nils Christian & Rudi, Knut (2013). Estimation of metagenome size and structure in an experimental soil microbiota from low coverage next-generation sequence data. Journal of Applied Microbiology.  ISSN 1364-5072.  114(1), s 141- 151 . doi: 10.1111/jam.12035
  • Håvelsrud, Othilde Else; Haverkamp, Thomas Hendricus Augustus; Kristensen, Tom; Jakobsen, Kjetill Sigurd & Rike, Anne Gunn Larsen (2013). Metagenomics in CO2 Monitoring. Energy Procedia.  ISSN 1876-6102.  37, s 4215- 4233 . doi: 10.1016/j.egypro.2013.06.324 Full text in Research Archive. Show summary
  • Malmstrøm, Martin; Jentoft, Sissel; Gregers, Tone Fredsvik & Jakobsen, Kjetill Sigurd (2013). Unraveling the Evolution of the Atlantic Cod’s (Gadus morhua L.) Alternative Immune Strategy. PLoS ONE.  ISSN 1932-6203.  8(9) . doi: 10.1371/journal.pone.0074004 Full text in Research Archive.
  • Orr, Russell; Stüken, Anke; Murray, Shauna A. & Jakobsen, Kjetill Sigurd (2013). Evolution and Distribution of Saxitoxin Biosynthesis in Dinoflagellates. Marine Drugs.  ISSN 1660-3397.  11(8), s 2814- 2828 . doi: 10.3390/md11082814
  • Orr, Russell; Stüken, Anke; Murray, Shauna A. & Jakobsen, Kjetill Sigurd (2013). Evolutionary Acquisition and Loss of Saxitoxin Biosynthesis in Dinoflagellates: the Second "Core" Gene, sxtG. Applied and Environmental Microbiology.  ISSN 0099-2240.  79(7), s 2128- 2136 . doi: 10.1128/AEM.03279-12 Full text in Research Archive.
  • Sogge, Hanne; Rohrlack, Thomas; Rounge, Trine Ballestad; Sønstebø, Jørn Henrik; Tooming-Klunderud, Ave; Kristensen, Tom & Jakobsen, Kjetill Sigurd (2013). Gene flow, recombination, and selection in cyanobacteria: population structure of geographically related Planktothrix Freshwater Strains. Applied and Environmental Microbiology.  ISSN 0099-2240.  79(2), s 508- 515 . doi: 10.1128/AEM.02417-12 Full text in Research Archive. Show summary
  • Star, Bastiaan; Haverkamp, Thomas Hendricus Augustus; Jentoft, Sissel & Jakobsen, Kjetill Sigurd (2013). Next generation sequencing shows high variation of the intestinal microbial species composition in Atlantic cod caught at a single location. BMC Microbiology.  ISSN 1471-2180.  13:248 . doi: 10.1186/1471-2180-13-248
  • Stüken, Anke; Dittami, Simon; Eikrem, Wenche; McNamee, Sara; Campbell, Katrina; Jakobsen, Kjetill Sigurd & Edvardsen, Bente (2013). Novel hydrolysis-probe based qPCR assay to detect saxitoxin transcripts of dinoflagellates in environmental samples. Harmful Algae.  ISSN 1568-9883.  28, s 108- 117 . doi: 10.1016/j.hal.2013.06.003
  • Tooming-Klunderud, Ave; Sogge, Hanne; Rounge, Trine Ballestad; Nederbragt, Alexander Johan; Lagesen, Karin; Glöckner, Gernot; Hayes, Paul K; Rohrlack, Thomas & Jakobsen, Kjetill Sigurd (2013). From Green to Red: Horizontal Gene Transfer of the Phycoerythrin Gene Cluster between Planktothrix Strains. Applied and Environmental Microbiology.  ISSN 0099-2240.  79(21), s 6803- 6812 . doi: 10.1128/AEM.01455-13 Full text in Research Archive.
  • Dittami, Simon; Riisberg, Ingvild; John, Uwe; Orr, Russell; Jakobsen, Kjetill Sigurd & Edvardsen, Bente (2012). Analysis of Expressed Sequence Tags from the Marine Microalga Pseudochattonella farcimen (Dictyochophyceae). Protist.  ISSN 1434-4610.  163(1), s 143- 161 . doi: 10.1016/j.protis.2011.07.004
  • Espelund, Mari; Minge, Marianne Aastebøl; Gabrielsen, Tove M; Nederbragt, Alexander Johan; Shalchian-Tabrizi, Kamran; Otis, Christian; Turmel, Monique; Lemieux, Claude & Jakobsen, Kjetill Sigurd (2012). Genome Fragmentation Is Not Confined to the Peridinin Plastid in Dinoflagellates. PLoS ONE.  ISSN 1932-6203.  7(6) . doi: 10.1371/journal.pone.0038809 Full text in Research Archive.
  • Håvelsrud, Othilde Else; Haverkamp, Thomas Hendricus Augustus; Kristensen, Tom; Jakobsen, Kjetill Sigurd & Rike, Anne Gunn Larsen (2012). Metagenomic and geochemical characterization of pockmarked sediments overlaying the Troll petroleum reservoir in the North Sea. BMC Microbiology.  ISSN 1471-2180.  12(203) . doi: 10.1186/1471-2180-12-203 Full text in Research Archive.
  • Marcussen, Thomas; Jakobsen, Kjetill Sigurd; Danihelka, Jiří; Ballard, Harvey E.; Blaxland, Kim; Brysting, Anne Krag & Oxelman, Bengt (2012). Inferring Species Networks from Gene Trees in High-Polyploid North American and Hawaiian Violets (Viola, Violaceae). Systematic Biology.  ISSN 1063-5157.  61(1), s 107- 126 . doi: 10.1093/sysbio/syr096
  • Orr, Russell; Murray, Shauna A.; Stüken, Anke; Rhodes, Lesley & Jakobsen, Kjetill Sigurd (2012). When Naked Became Armored: An Eight-Gene Phylogeny Reveals Monophyletic Origin of Theca in Dinoflagellates. PLoS ONE.  ISSN 1932-6203.  7(11) . doi: 10.1371/journal.pone.0050004 Full text in Research Archive.
  • Siddiqui, Huma; Lagesen, Karin; Nederbragt, Alexander Johan; Jeansson, Stig & Jakobsen, Kjetill Sigurd (2012). Alterations of microbiota in urine from women with interstitial cystitis. BMC Microbiology.  ISSN 1471-2180.  12(205) . doi: 10.1186/1471-2180-12-205 Full text in Research Archive.
  • Yashchenko, Varvara; Gavrilova, Olga V; Rautian, Maria S & Jakobsen, Kjetill Sigurd (2012). Association of Paramecium bursaria Chlorella viruses with Paramecium bursaria cells: Ultrastructural studies. European Journal of Protistology.  ISSN 0932-4739.  48(2), s 149- 159 . doi: 10.1016/j.ejop.2011.05.002
  • Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin; Gregers, Tone Fredsvik; Rounge, Trine Ballestad; Paulsen, Jonas; Solbakken, Monica Hongrø; Sharma, Animesh; Wetten, Ola Frang; Lanzén, Anders; Winer, Roger; Knight, James; Vogel, Jan-Hinnerk; Aken, Bronwen; Andersen, Øivind; Lagesen, Karin; Tooming-Klunderud, Ave; Edvardsen, Rolf; Kirubakaran, G. Tina; Espelund, Mari; Nepal, Chirag; Previti, A. Christopher; Karlsen, Bård Ove; Moum, Truls; Skage, Morten; Berg, Paul Ragnar; Gjøen, Tor; Kuhl, Heiner; Thorsen, Jim; Malde, Ketil; Reinhardt, Richard; Du, Lei; Johansen, Steinar Daae; Searle, Steve; Lien, Sigbjørn; Nilsen, Frank; Jonassen, Inge; Omholt, Stig W; Stenseth, Nils Christian & Jakobsen, Kjetill Sigurd (2011). The genome sequence of Atlantic cod reveals a unique immune system. Nature.  ISSN 0028-0836.  477(7363), s 207- 210 . doi: 10.1038/nature10342 Full text in Research Archive.

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  • Reinar, William Brynildsen; Tørresen, Ole K.; Matschiner, Michael; Jentoft, Sissel; Nederbragt, Alexander Johan & Jakobsen, Kjetill Sigurd (2018). The impact of repetitive DNA on speciation rates in teleost fish.
  • Tørresen, Ole K.; Skrede, Inger; Sandve, Simen Rød; Jentoft, Sissel; Jakobsen, Kjetill Sigurd & Borge, Ole Johan (2018). Gendykk i norsk natur gir ny kunnskap. Genialt.  ISSN 0804-225X.  (4), s 16- 18
  • Barth, Julia Maria Isis; Star, Bastiaan; Matschiner, Michael; André, Carl; Knutsen, Halvor; Bradbury, Ian; Dierking, Jan; Petereit, Christoph; Righton, David; Metcalfe, Julian; Jakobsen, Kjetill Sigurd; Olsen, Esben Moland & Jentoft, Sissel (2017). Chromosomal rearrangements as barriers to homogenization in highly mobile fish.
  • Barth, Julia Maria Isis; Star, Bastiaan; Matschiner, Michael; André, Carl; Knutsen, Halvor; Bradbury, Ian; Dierking, Jan; Petereit, Christoph; Righton, David; Metcalfe, Julian; Jakobsen, Kjetill Sigurd; Olsen, Esben Moland & Jentoft, Sissel (2017). Chromosomal rearrangements as barriers to homogenization in highly mobile fish.
  • Evjen, Tove Julie; Dick, Gunnar; Skogli, Erik Winther; Høiseth-Gilje, Kaja; Jakobsen, Kjetill Sigurd & Tasken, Kjetil (2017). Den digitale bioteknologien i Norge - Muligheter for verdiskaping, kompetansebehov og utfordringer i næringsutvikling.
  • Matschiner, Michael; Star, Bastiaan; Barth, Julia Maria Isis; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2017). Genomic rearrangements a phylogenetic approach.
  • Sandve, Simen Rød; Hvidsten, Torgeir Rhoden; Lien, Sigbjørn; Rori, Rohlfs; Jakobsen, Kjetill Sigurd; Nome, Torfinn; Varadharajan, Srinidhi; Nederbragt, Alexander Johan & Vøllestad, Leif Asbjørn (2017). Evolution after whole genome duplication - insights from the salmonids.
  • Skage, Morten; Barth, Julia Maria Isis; Jentoft, Sissel; Øverli, Øyvind & Jakobsen, Kjetill Sigurd (2017). Genetisk bakgrunn hos ulv (Canis lupus) i Norge og Skandinavia. Full text in Research Archive. Show summary
  • Eide, Marta; Puntervoll, Pål; Lille-Langøy, Roger; Goldstone, Jared V.; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Rydbeck, Halfdan; Jakobsen, Kjetill Sigurd; Stegeman, John; Goksøyr, Anders & Karlsen, Odd Andre (2016). Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor.
  • Barth, Julia Maria Isis; Star, Bastiaan; Matschiner, Michael; Berg, Paul Ragnar; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2016). Ancient genomic variation separates Atlantic cod ecotypes; implications for management.
  • Knudsen, Jonfinn B.; Reinar, William B. & Jakobsen, Kjetill Sigurd (2016). Evolutionary and functional importance of simple repeats in eukaryotic genomes.
  • Rose, Carina; Torgersen, Eivind; Ørmen, Torfinn; Høiland, Klaus & Jakobsen, Kjetill Sigurd (2016, 28. november). Hva er egentlig en art?. [Internett].  http://forskning.no/2016/11/-biologi-hva-er-egentlig-en-art.
  • Baalsrud, Helle Tessand; Tørresen, Ole Kristian; Malmstrøm, Martin; Salzburger, Walter; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2015). The hemoglobin repertoire in the order of Gadiformes linked to depth adaptation.
  • Jakobsen, Kjetill Sigurd (2015, 10. februar). Scientists study teeth and gerbils to further understand plague. [Internett].
  • Jakobsen, Kjetill Sigurd (2015). Store datamengder.
  • Jakobsen, Kjetill Sigurd (2015). The Codfather - Toppforsker på fisketur.
  • Nilsson, Pernille & Jakobsen, Kjetill Sigurd (2015). Finner DNA-rester av pestbakterier fra svartedauden. Apollon : Forskningsmagasin for Universitetet i Oslo.  ISSN 0803-6926.
  • Nilsson, Pernille & Jakobsen, Kjetill Sigurd (2015). Pestbakterier fra jernalder og svartedauden analyseres i Norge. Aftenposten (morgenutg. : trykt utg.).  ISSN 0804-3116.
  • Star, Bastiaan; Jentoft, Sissel; Matschiner, Michael; Nederbragt, Alexander Johan; Kjesbu, Olav Sigurd; Berg, Paul Ragnar; Bradbury, Ian R.; Pampoulie, Christophe; Hansen, Marianne Helén Selander; Skage, Morten; Jakobsen, Kjetill Sigurd & Stenseth, Nils Christian (2015). Does historic DNA provide genomic evidence for recent selection in Atlantic cod?.
  • Berg, Paul Ragnar; Jentoft, Sissel; Star, Bastiaan; Ring, Kristoffer Hofaker; Knutsen, Halvor; Lien, Sigbjørn; Jakobsen, Kjetill Sigurd & André, Carl (2014). Adaptation to low salinity promotes genomic divergence in Atlantic cod (Gadus morhua L.).
  • Brynildsen, William; Tørresen, Ole Kristian; Jakobsen, Kjetill Sigurd & Nederbragt, Alexander Johan (2014). Genomic sequence repeats in fish genomes.
  • Jakobsen, Kjetill Sigurd (2014, 28. mars). Amerikanere skaber kunstigt kromosom. [Internett].
  • Jakobsen, Kjetill Sigurd (2014, 28. mars). Menneskeskapt kromosom puttet inn i levende sopp-celle. [Internett].
  • Jakobsen, Kjetill Sigurd (2014, 28. mars). Menneskeskapt kromosom puttet inn i levende sopp-celle. [Internett].
  • Jakobsen, Kjetill Sigurd (2014, 07. mars). Quicker and cheaper toxicity checking of mussels. [Internett].
  • Jakobsen, Kjetill Sigurd (2014, 27. februar). Raskere og billigere giftsjekk av blåskjell. [Internett].
  • Jakobsen, Kjetill Sigurd (2014). The Aqua Genome project - 1000 genomes of Atlantic cod and salmon makes a difference.
  • Jakobsen, Kjetill Sigurd (2014, 04. desember). Vi druknar i informasjon. [Internett].
  • Matschiner, Michael; Star, Bastiaan; Berg, Paul Ragnar; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Hansen, Marianne Helén Selander; Skage, Morten; Kjesbu, Olav Sigurd; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2014). Population differentiation and local adaptation in Atlantic cod.
  • Nederbragt, Alexander Johan; Walenz, Brian; Tørresen, Ole Kristian; Jentoft, Sissel; Jakobsen, Kjetill Sigurd & Miller, Jason Rafe (2014). Towards correction-free assembly of raw PacBio reads.
  • Nilsson, Pernille; Easterday, William Ryan; Schmid, Boris Valentijn; Jentoft, Sissel; Jakobsen, Kjetill Sigurd; Zhange, Yujiang; yang, Ruifu & Stenseth, Nils Christian (2014). Plague and the Chinese experience – how to collaborate and work in China.
  • Tørresen, Ole Kristian; Jentoft, Sissel; Star, Bastiaan; Sandve, Geir Kjetil F.; Skage, Morten; Hansen, Marianne Helén Selander; Tooming-Klunderud, Ave; Jakobsen, Kjetill Sigurd & Nederbragt, Alexander Johan (2014). A new, high quality reference genome assembly for Atlantic cod.
  • Tørresen, Ole Kristian; Walenz, Brian; Grove, Harald; Lien, Sigbjørn; Knight, James; Star, Bastiaan; Lagesen, Karin; Sandve, Geir Kjetil F.; Skage, Morten; Hansen, Marianne Helén Selander; Klunderud, Ave Tooming; Miller, Jason Rafe; Jentoft, Sissel; Jakobsen, Kjetill Sigurd & Nederbragt, Alexander Johan (2014). A new, high quality reference genome assembly for Atlantic cod.
  • Jakobsen, Kjetill Sigurd (2013, 14. mars). Bar på urgammelt Y-kromosom. [Internett].  http://www.forskning.no/artikler/2013/mars/350666.
  • Rike, Anne Gunn Larsen; Håvelsrud, Othilde Else; Haverkamp, Thomas Hendricus Augustus; Kristensen, Tom & Jakobsen, Kjetill Sigurd (2013). Metagenomics in methane seep detection and studies of the microbial methane sediment filter.
  • Solbakken, Monica Hongrø; Jentoft, Sissel; Seppola, Marit; Mikkelsen, Helene & Jakobsen, Kjetill Sigurd (2013). The immune system of Atlantic cod.
  • Solbakken, Monica Hongrø; Malmstrøm, Martin; Tørresen, Ole Kristian; Jakobsen, Kjetill Sigurd & Jentoft, Sissel (2013). Atlantic cod displays an unusual TLR repertoire – a Gadidae-specific feature?.
  • Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Miller, Jason Rafe; Walenz, Brian; Jentoft, Sissel & Jakobsen, Kjetill Sigurd (2013). Improving the Atlantic cod genome using long-read PacBio in combination with 454 and Illumina sequencing data.
  • Nederbragt, Alexander Johan; Tørresen, Ole Kristian; Skage, Morten; Tooming-Klunderud, Ave; Hansen, Marianne Helén Selander; Jentoft, Sissel; Omholt, Stig W; Lien, Sigbjørn & Jakobsen, Kjetill Sigurd (2012). The long jump: Long distance mate pairs and long PacBio reads for the Salmon Genome Project.
  • Haverkamp, Thomas Hendricus Augustus; Hammer, Øyvind & Jakobsen, Kjetill Sigurd (2012). Comparative analysis of microbial diversity of pockmark sediments of the Oslo Fjord.
  • Nederbragt, Alexander Johan; Tørresen, Ole Kristian; Khelik, Ksenia; Lagesen, Karin; Rounge, Trine Ballestad; Star, Bastiaan; Tina, Kirubakaran G.; Berg, Paul Ragnar; Rognes, Torbjørn; Jentoft, Sissel; Winer, Roger; Dewar, Ken & Jakobsen, Kjetill Sigurd (2012). Challenges and Opportunities for Improving the Atlantic Cod Genome Assembly and Annotation.
  • Orr, Russell; Stüken, Anke & Jakobsen, Kjetill Sigurd (2012). Molecular detection of saxitoxin-producing dinoflagellates using the gene sxtG.
  • Stüken, Anke; Figueroa, Rosa; Orr, Russell & Jakobsen, Kjetill Sigurd (2012). Is sxt gene copy number related to saxitoxin synthesis?.
  • Stüken, Anke; Orr, Russell; Jakobsen, Kjetill Sigurd; Murray, Shauna A. & Neilan, Brett A. (2012). DETECTION OF SAXITOXIN-PRODUCING DINOFLAGELLATES.
  • Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Lagesen, Karin; Khelik, Ksenia; Rognes, Torbjørn; Jentoft, Sissel & Jakobsen, Kjetill Sigurd (2012). Improving the cod genome with the use of multi-platform sequencing data.

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Published May 26, 2011 9:47 PM - Last modified Oct. 5, 2018 2:45 PM