Abstract
Mode of delivery and breastfeeding strongly shape the composition of infant gut microbiota, with persistent and potentially interactive effects throughout the year of life. Cesarean section delivery alters composition soon after birth with some of these changes lingering at 1 year of life. Breastfeeding appears to influence microbiota diversity differently at age 3 months versus 1 year. Ongoing research in the CHILD study will address the cumulative and long-term impact of these and other early-life exposures, and associated changes to the gut microbiota, on the development of allergic disease and other health outcomes.
Anita Kozyrskyj
Department of Pediatrics
Faculty of Medicine & Dentistry
3-527 Edmonton Clinic Health Academy
School of Public Health
University of Alberta
Update 29 November: Following the regular seminar, Siddhartha Mandal, postdoc at the Norwegian Institute of Public Health, will give a 15 minute "bonus lecture" on "Are we analyzing sequenced data correctly? CoMicZ, a statistical framework which correctly takes relativetly into account and increases your power".