Ragnhild Elisabeth Heimtun Paulsen

Image of Ragnhild Elisabeth Heimtun Paulsen
Norwegian version of this page
Phone +47 22844936
Room 253 ZEB-bygningen
Username
Visiting address Sem Sælands vei 3 Farmasibygningen 0371 OSLO
Postal address Postboks 1068 Blindern 0316 OSLO

Academic interests

Our research interests are molecular mechanisms of cell death and cell survival in the central nervous system. We use neuronal cell cultures as experimental models. Many of our studies involve glutamate, which is a neurotransmitter in the CNS that in high extracellular concentrations causes cell death e.g. following a stroke; or drugs such as glucocorticoids. Important findings are that certain steriods protect against glutamate-induced cell death; glutamate-induced cell death is caused by ROS, tranlocation of NGFI-B to the mitochondria, and caspase-3 activation.

Teaching

Higher education and employment history

Education:

  • Dr.philos, University of Oslo, 1989
  • Cand.pharm., University of Oslo, 1985

Employment history:

  • Professor, School of Pharmacy, University of Oslo, since 1996
  • Associate Professor, School of Pharmacy, University of Oslo 1995-1996
  • Sabbatical, Washington University School of Medicine, St. Louis, 1990-1992
  • Sabbatical, FIDIA-Georgetown Institute for the Neurosciences, Washington DC, 1989-1990
  • Scientist, Norwegian Defense Research Establishment, 1987-1995
  • PhD student (Norwegian Research Council), 1985-1987

Boards

  • Secretary, Norwegian Neuroscience Society
  • Member, Department board, School of Pharmacy, University of Oslo, 2013-2016

 

Tags: Pharmacology, Neurobiology, Neurotoxicology, Molecular neurobiology, Glutamate toxicity, Transcription factors
Published Nov. 17, 2010 3:26 PM - Last modified Nov. 22, 2019 2:37 PM