Inger Oulie

Image of Inger Oulie
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Phone +47 22856574
Room 209
Username
Visiting address Sem Sælands vei 3 Farmasibygningen 0371 OSLO
Postal address Postboks 1068 Blindern 0316 OSLO

Working areas

Analysis and identification of peptides, proteins and drugs with LC/MS and HPLC/UV, including trypsinization, sample preparation and purification (with magnetic beads, antibodies, SPE and PALME).
Responsibile for the operation and maintenance of instruments (HPLC/MS  and HPLC/UV) and training of personell in use of the instruments.
Practical facilitation and guidance in laboratory courses:

FARM2030 - Legemiddelanalyse

FRM3030 - Bruk av legemidler, del III

FRM4020 - Forskningsforberedende kurs i legemiddelanalyse

 

Background

Master in Biomedicine and medical laboratory scientist with broad experience from pharmaceutical industry with an emphasis on documenting new substances in the early stages of projects, including responsibility for the documentation of the product in accordance with applicable quality standards (GLP / GMP).
 
Extensive experience in the development, verification / validation and documentation of analytical methods for biological- and chemical analyzes and biochemical characterization of various substances in biological and chemical samples with different analytical techniques.

 

Tags: Mass spectrometry, HPLC, Chromatography, Biochemical analysis, Sample preparation, Bioanalysis, Uptake of nanoparticles in cells

Publications

Nucl. Med. Biol. 42,9,(2015) 711-719: Chau W.-F., Black A. M. A, Clarke A., Durrant C., Gausemel I., Khan I., Mantzilas D., Oulie I., Rogstad A., Trigg W., Jones P.A.: Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [18F]GE-180. 

Acta Rad.: 51,9 (2010) 1014-1020: Wistrand L.G., Rogstad A.,Hagelin G., Roed L., Oulie I., Gram A., Evans P., Rasmussen H., Grant D., Iveson P., Newton B., Thaning M.: GE-145, a new low-osmolar dimeric radiographic contrast medium.

Eur. J. of Pharm. Sci. 37 (2009) 279-283: Røed L., Oulie I.,  McParland B.J., Skotland T.: Human urinary excretion of NC100692, an RGD-peptide for imaging  angiogenesis.

J. Nucl. Med. (6) 2008, 879-886: Kenny L.M., Combes R.C., Oulie I., Contractor K.B., MillerM., Spinks T.J., McParland B., Cohen P.S., Hui A.M.,Palmeiro C., Osman S., Glaser M., Turton D., Al-Nahnas A., Aboague EO.: Phase 1 Clinical Trial of the Positron-Emmiting Arg-Gly-Asp (RGD) peptide Radioligand 18F-AH111585 in Breast Cancer Patient

J. Pharm. Biomed. Anal.:  47 (2008) 164-169: Røed L., Oulie I., Toft K.G.,Knüttel T.; Hustvedt S.O.,  Skotland T.: Metabolism in rats of NC100692, an RGD-peptide for imaging of angiogenesis.

Drug Metabolism and Disposition: 35,11 (2007) 1-6: Toft K.G., Johnson J.A, Oulie I., Skotland T.: NC100668, a New Tracer Tested for Imaging of Venous Thromboembolism: Pharmacokinetics and Metabolism in Human.

J. of Chrom. B; 852 (2007) 605-10, Oulie I., Røed L., Toft K.G., Skotland T.: Quantification of NC100692, a new tracer for 99mTc-imaging of angiogenesis,  in human plasma using reversed-phase liquid chromatography coupled with electrospray ionization ion-trap mass spectrometry.

Ultrasound in Med&Biol: 32 no.1 (2006) 107-120: Toft K.G., Hustvedt S.O., Hals P.A., Oulie I., Uran S., Landmark K.E., Normann P.T., Skotland T.: Disposition of perfluorobutan in rats after intravenous injection of Sonazoid.

Drug Metabolism and Disposition: 34 (2006) 111-120: Skotland T., Hustvedt S.O., Oulie I., Jacobsen P.B., Friisk G.A., Langøy A.S., Uran S., Sandosham J., Cuthbertson A., Toft K.G.: NC100668, a new tracer for imaging of venous thromboembolism:disposition and metabolism in rats.

J. of Chrom. B.: 829 (2005) 91-96: Toft K.G., Oulie I., Skotland T.: Quantification of NC100668, a new tracer for imaging of venous thromboembolism, in human plasma using reversed-phase liquid chromatography coupled with electrospray ionization ion-trap mass spectrometry.

J. of Chrom. B: 811 (2004) 243-251: Hagelin G., Oulie I., Raknes Å., Undheim K., Clausen O.G.: Preparative high-performance liquid chromatography separation and analysis of the Maltacine complex – a family of cyclic peptide antibiotics from Bacillus subtilis.

J. Pharm. Biomed. Anal.:  28 (2002) 323-329: Skotland T, Sontun P.C., Oulie I.: In vitro stability analysis as a model for metabolism of ferromagnetic particles (ClariscanTM), a contrast agent for magnetic resonance imaging.

Acta Radiol. 42 (2001)117-120: P. Balke Jacobsen, I. Oulie, C. Christiansen and T. Skotland: Investigation of binding of 125I-Iodixanol to high molecular weight substances after incubation with rat liver homogenates.

J. Pharm. Biomed. Anal.: 24 (2001) 487-494: Hvattum E, Normann P.T., Oulie I., Uran S., Ringstad O., Skotland T.: Determination of perfluorobutane in rat blood by automatic headspace capillary gas chromatography and selected ion monitoring mass spectrometry.

Published Dec. 4, 2015 3:00 PM - Last modified Oct. 24, 2019 8:34 AM

Research groups