Academic interests
- Medicinal Chemistry
- Organic Synthesis
- Natural Product Synthesis
Teaching
Higher education and employment history
- Principal Engineer, Section for Pharmaceutical Chemistry, Department of Pharmacy, University of Oslo, 2025 -
- M.Sc. in Chemical Engineering (synthetic organic chemistry), Norwegian University of Science and Technology, 2019 - 2025
Tags:
Organic chemistry,
Synthetic organic chemistry,
Medicinal chemistry,
Natural product synthesis,
Handling of chemicals,
Laboratory safety
Publications
-
Rolfsen, Jacob Strand; Cherukupalli, Srinivasulu; Sundby, Eirik & Hoff, Bård Helge
(2026).
Triazole-Functionalized 7-Azaindoles: A synthetic Study Using Sonogashira Cross-Coupling and Copper-Catalyzed Azide-Alkyne Cycloaddition.
Full text in Research Archive
Show summary
The majority of recently approved small-molecule drugs contain at least one nitrogen heterocycle.1 Among these, the 7-azaindole scaffold is recognized as a
kinase-privileged fragment and is featured in several commercial inhibitors, including the colony-stimulating factor 1 receptor inhibitor Pexidartinib.2 Likewise,
1,2,3-triazoles have emerged as significant motifs in drug discovery due to their ease of synthesis and broad pharmacological activity.3,4 Combining structural
features of Pexidartinib and 1,2,3-triazoles, herein we outline our latest work on triazole functionalized 7-azaindoles.
View all works in NVA
Published
Jan. 30, 2026 6:58 AM
- Last modified
May 5, 2026 10:51 AM
