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LIPCHEM

The LIPCHEM group combines synthetic organic chemistry, medicinal chemistry and total organic synthesis to study the chemistry and biology of lipids, particularly metabolites of the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

 

LIPCHEM researchers group photo

Photo: LIPCHEM-group September 2021

Projects

In the last 10 years or so, we have contributed to several syntheses of specialized pro-resolving mediators (protectins, resolvins and maresins), as well as analogs. This has contributed to the study of their biology and biochemical pathways. More recently, we have also initiated projects in medicinal chemistry towards fatty acid epoxides, their ethanolamides, and stable mimics thereof. In addition, we have contributed to the development of new methodology within synthetic organic chemistry, and the identification of new lead compounds in medicinal chemistry projects targeting diseases such as cancer. These life science oriented projects are conducts in collaboration with groups both abroad and in Norway (see below). For more details on our research, please see the Publications list on the left menu.

Collaborations

Professor Charles N. Serhan, Harvard Medical School, USA.

Professor Jesmond Dalli, The Barts and The London School of Medicine and Dentistry and Queen Mary College, William Harvey Research Institute, UK.

Professor Bruce D. Hammock, University of California, Davis, USA.

Professor Toshinori Hoshi, Perelman School of Medicine, University of Pennsylvania

Associate Research Fellow Jing-Jy Cheng, National Research Institute of Chinese Medicine, Taipei, Taiwan.

Professor Pål Aukrust, Oslo University Hospital, Norway.

Professor James Lorens, University of Bergen, Norway.

Professor Yngve Stenstrøm, Norwegian University of Life Sciences, Norway.

Professor Ingebrigt Sylte, University of Tromsø, Norway.

Professor Jeanette Hammer Andersen, University of Tromsø, Norway.

Associate professor Eirik Johansson Solum, Nord University, Namsos, Norway

 

In addition we have internal cooporation with other research groups at the Department of Pharmacy, University of Oslo

 

Teaching

Members of LIPCHEM are currently involved in the teaching of the following courses at the Department of Pharmacy:

FARM1100 - Pharmaceutical chemistry

FARM1130 - Pharmaceutically based organic chemistry

FARM1150 - Pharmaceutically based biochemistry

FARM2100 - Medicinal chemistry

FARM4120 - Drug development

FRM5000 - Preparation course for master in pharmacy

FARM5110 - Industrial pharmacy

FARM5190 - Synthesis of bioactive compounds

 

Tags: Life Science, Organic chemistry, Total syntheis, Natural product synthesis, Chemistry, Medicinal chemistry, Polunsaturated Fatty Acids, Livsvitenskap, Legemiddelkjemi, Organisk kjemi, Naturstoffkjemi, Kjemi, Totalsyntese, USA
Published Mar. 17, 2015 11:59 AM - Last modified June 22, 2022 1:15 PM