New articles in January and February 2019

Three new international articles from PharmaSafe in January and February 2019!


Article 1:

107 women with hyperemesis gravidarum report lack of support, concerns about medication use and profound consequences on their daily lives (Havnen et al 2010).

This is a must read for all health care personnel in care of pregnancy women with nausea and vomiting in pregnancy.

 “I did not receive any treatment. I was told not to take any anti-emetic medications. I did not get any advice other than to eat some crackers”.

Woman with HG hospitalized for 7 days, 18% weight loss

Article 2:

401 women with migraine overestimate the risks of antimigraine medications to the unborn child despite that over 70% had to use medication to tackle migraine attacks in pregnancy. They report concerns about their own health and medications, lack of knowledge among health care personnel and questions about breast feeding (Amundsen et al 2019).

Taking time to understand the woman’s perspectives and concerns is essential for providing optimal health care to this patient group.

“I was afraid it would harm by baby. My doctor discouraged me from taking any migraine medications while pregnant if I could manage without it, so I did. He recommended sick-leave before use of medications so I have been on sick-leave from week 10”.
Pregnant woman with migraine, 32 years, refraining from use of sumatriptan, paracetamol and ibuprofen during pregnancy

Article 3:

877 individuals in 20 pharmacies in 3 Norwegian cities: 57% had high knowledge about antibiotics in general and 71% had high knowledge of antibiotic resistance. Men with lower education in vocational professions have the lowest knowledge about antibiotics and antibiotic resistance among Norwegian pharmacy customers (Waalseth et al 2019).

We recommend that the Norwegian Directorate of Health should target this group in future public antibiotic campaigns.


Women's perspectives on the management and consequences of hyperemesis gravidarum – a descriptive interview study. Havnen GC, Truong MB, Do MH, Heitmann K, Holst L, Nordeng H. Scand J Prim Health Care. 2019 Mar 1:1-11.

Risk perception, beliefs about medicines and medical adherence among pregnant and breastfeeding women with migraine: findings from a cross-sectional study in Norway. Amundsen S, Øvrebø TG, Amble NMS, Poole AC, Nordeng H. BMJ Open. 2019 Feb 27;9(2):e026690.

Knowledge of antibiotics and antibiotic resistance among Norwegian pharmacy customers - a cross-sectional study. Waaseth M, Adan A, Røen IL, Eriksen K, Stanojevic T, Halvorsen KH, Garcia BH, Holst L, Ulshagen KM, Blix HS, Ariansen H, Nordeng HME. BMC Public Health. 2019 Jan 15;19(1):66. doi: 10.1186/s12889-019-6409-x.

Published Mar. 4, 2019 2:28 PM - Last modified Mar. 4, 2019 2:41 PM