The Biennial Conference of the International Marcé Society is a clinically oriented meeting that provides important input in psychiatric pharmacoepidemiology. The two key teams of this year’s conference were (i) re-conceptualizing “treatment resistance” as “difficult to treat” and (ii) DSM revision of postpartum psychosis. The meeting provided the opportunity to meet up with our collaborators from the COST network RISE-UP PPD CA18138 where Angela leads the working group on psychopharmacology and colleagues from the Nordic Marcé Society.