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Photo: marleenvangelder.com Exposure to Systemic Antimicrobials During Pregnancy and Risk of Miscarriage: A Population-Based Registry Study Authors: Thomas Boissiere-O'Neill, Marleen M H J van Gelder, Hilde M Engjom, Hedvig M E Nordeng
Our population-based cohort study analyzed 704,082 pregnancies to assess the risk of miscarriage associated with systemic antimicrobial exposure in early pregnancy. The results indicated that common antimicrobials like nitrofurantoin, pivmecillinam, and amoxicillin did not elevate miscarriage risk, while others like metronidazole and ciprofloxacin were linked with increased risk. This research is significant for providing a clearer picture of potential risks and biases linked to antimicrobial use during pregnancy.
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Tackling Medication Errors: How a Systems Approach Improves Patient Safety Authors: Sonja Guntschnig, Renata Barbosa, Helena Jenzer, Matthew Greening, Jennifer Hayde, Helen Heery, Maria Cristina Iglesias Serrano, Kristína Lajtmanová, Elisabetta Rossin, Slagjana Tentova-Peceva, Stephanie Kohl, Alma Mulac
Focusing on medication errors as a leading source of harm in healthcare, this paper presents a systems approach to improve patient safety across European healthcare systems. By analyzing 89 anonymized medication error reports, we identified root causes and proposed comprehensive strategies for prevention, emphasizing that robust governance and improved safety cultures are essential in mitigating these errors. Automation and strategic policy enhancements were recommended to bolster medication safety frameworks.
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Photo: UiO.no Agreement Between Parental Self-Reported Antiseizure Medication Use and Dispensed Prescription Records From a National Prescription Database Authors: Emilie Willoch Olstad, Hedvig Nordeng, Marte-Helene Bjørk, Kaja Kristine Selmer, Kristina Gervin
This study investigates the accuracy of self-reported antiseizure medication use during pregnancy, utilizing data from the Norwegian Prescription Database (NorPD) linked to the Norwegian Mother, Father, and Child Cohort Study (MoBa). With over 82,000 participants, our findings indicate a strong agreement between dispensed prescriptions and self-reported use, demonstrating a kappa value of 0.81 for both mothers and fathers. Notably, levetiracetam and lamotrigine exhibited the highest reliability. This work emphasizes the value of prescription data in evaluating the safety of antiseizure medications during pregnancy.
These publications reflect our ongoing commitment to enhancing medication safety and provide critical insights for practitioners and researchers alike. We encourage you to read the full articles for a deeper understanding of these crucial topics.