Dr. Renée Beekman
Dr. Renée Beekman, Group Leader at the Centre for Genomic Regulation, Barcelona, Spain, will present her lecture "Understanding early lymphoma formation from a single-cell epigenomics and 3D chromatin perspective."
Meet the speaker
If you want to meet Dr. Renée Beekman on Thursday April 28th in Forskningsparken, please book a time slot at https://doodle.com/meeting/participate/id/b82XKWLe. Please book an empty slot for maximum 1 hour and send an email to email@example.com to confirm the time.
Translocations and epigenetic changes are frequently found in cancer. However, how the epigenetic landscape evolves during early tumor formation and how translocations play a role in this process remain largely unexplored. Neither is it know if oncogenic epigenetic events occur in healthy individuals, which could provide seeds for positive selection and tumor formation. In this talk, I will present (i) a new single-cell DNA methylation method that we have developed in the lab to characterise the DNA methylation landscape in healthy B cells as well as (ii) a study of the global effects of translocations on 3D chromatin organization, using mantle cell lymphoma (MCL) as a model.
Roberto Rossini, PhD candidate at the Department of Biosciences, University of Oslo, will present his work on "MoDLE: High-performance stochastic modeling of DNA loop extrusion interactions."