Dr. Stephan Ossowski

Dr. Stephan Ossowski, Group Leader at the Institute for Medical Genetics and Applied Genomics, University of Tübingen, Germany, will present the lecture "Computational Analysis of NGS Data for Clinical Diagnostics."

Meet the Speaker

If you want to meet Dr. Stephan Ossowski, please book a time slot at https://doodle.com/poll/nstepim9xqsv99dh and send an email to anthony.mathelier@ncmm.uio.no.


In this talk, I will discuss the development and application of computational methods for clinical diagnostic sequencing. I will introduce machine learning and statistical approaches for the prioritization of causal variants for rare genetic diseases and for the identification of cancer driver genes using signatures of selection found in tumor genomes. Furthermore, I will introduce novel Nanopore sequencing-based methods used for epidemiologic analysis of outbreaks of multi-drug resistant bacteria, de novo assembly of genomes and identification of horizontal gene transfer of antimicrobial resistance genes.  Finally, I will show how these methods are translated to clinical praxis at the University Hospital Tübingen.



Junior talk

Milena Pavlovic, PhD student in the Biomedical Informatics Group, UiO, will present her work on "Machine learning approaches to decipher immune repertoires."

Published Aug. 13, 2019 11:08 AM - Last modified Aug. 13, 2019 11:09 AM