My overall interest has long been cardio-respiratory physiology of animals, in particular fish. I have worked a lot on the whole-animal level, i.e. using methods such as respirometry to investigate the effect of different environmental factors on respiration and aerobic scope, and in air-breathing fish also the effects on partioning of oxygen uptake between water and air. In my current project, however, since moving to Oslo after my PhD studies, I am investigating the molecular mechanisms enabling the anoxia tolerant crucian carp to survive with any oxygen for extended periods of time, and in particular how they survive the stress of subsequent re-oxygenation. I have recently conducted a transcriptomics study, and hope to build on this in my future research. Since coming to Oslo I have also had the opportunity to work on the effects of climate change on coral reef fish, and a tropical jumping snail. Though a side project, the research I conducted at Lizard Island on these snails actually received attention from the New York Times (Sciencetake), Science News (Science Ticker and It’s Alive) og Discovery Channel Canada! While my main research focus has shifted away from air-breathing fishes, the topic is still one of my interests, and I have done a few side projects on the Alaska blackfish, which even ended up on the cover of the Journal of Experimental Biology (JEB Cover).
Higher education and employment history
Ph.D., Dep. Bioscience, Zoophysiology, Aarhus University, Denmark, March 14th 2012
B.Sc., Dep. Bioscience, Genetics and Ecology, Aarhus University, Denmark, June 1st 2007
Norwegian Research Council 2017 (Young Research Talent): Re-oxygenation resilience - the overlooked element of anoxic survival
Nansen Foundation, December 2015: The effects of hypoxia acclimation on the air-breathing Alaska blackfish
Nansen Foundation, December 2013: Jumping tropical snails: a model for studying effects of global change on respiratory performance in coral reef invertebrates
Individual postdoctoral fellowship, Carlsberg foundation, July 1st 2013 - June 30th 2014: Regulation of apoptosis in anoxic crucian carp
Company of Biologists (section Journal of Experimental Biology), March-April 2013: The importance of air-breathing for Alaska blackfish Dallia pectoralis
Company of Biologists (through Society of Experimental Biology), March-April 2013: The importance of air-breathing for Alaska blackfish Dallia pectoralis
Experience from abroad
- Experimental work during PhD study: “Oxygen requirements of the two air-breathing fish Pangasianodon hypophthalmus and Channa striata”, Can Tho City, Vietnam, 21 months in total
- Experimental work during BSc study: “Morphology, visitation and pollen deposition in Cordia globosa and Morinda citrifolia, two common Caribbean shrubs”. The Commonwealth of Dominica (The West Indies), 5 months
8. Sjannie Lefevre, Do Thi Thanh Huong, Tobias Wang, Nguyen Thanh Phuong, Mark Bayley (2012) Effects of hypoxia on the rise in metabolism and partitioning of oxygen uptake during digestion in the air-breathing fish Channa striata. Aquaculture 364–365, pp. 137–142.
7. Sjannie Lefevre, Frank B Jensen, Do Thi Thanh Huong, Tobias Wang, Nguyen Thanh Phuong, Mark Bayley (2012) Haematological and ion regulatory effects of nitrite in the air-breathing snakehead fish Channa striata. Aquatic Toxicology 118-119, pp. 48-53.
6. Angela Fago, Frank B. Jensen, Bruno Tota, Martin Feelisch, Kenneth R. Olson, Signe Helbo, Sjannie Lefevre, Daniele Mancardi, Anna Palumbo, Guro K. Sandvik, Nini Skovgaard (2012) Integrating nitric oxide, nitrite and hydrogen sulfide signaling in the physiological adaptations to hypoxia: A comparative approach. Comparative Biochemistry and Physiology Part A 162(1), pp. 1-6.
5. Sjannie Lefevre, Frank B Jensen, Do Thi Thanh Huong, Tobias Wang, Nguyen Thanh Phuong, Mark Bayley (2011) Effects of nitrite exposure on functional haemoglobin levels, bimodal respiration, and swimming performance in the facultative air-breathing fish Pangasianodon hypophthalmus. Aquatic Toxicology 104, pp. 86-93.
4. Sjannie Lefevre, Do Thi Thanh Huong, Nguyen Thi Kim Ha, Tobias Wang, Nguyen Thanh Phuong, Mark Bayley (2011) A telemetry study of swimming depth and oxygen level in a Pangasius pond in the Mekong Delta. Aquaculture 315, pp. 410-413.
3. Sjannie Lefevre, Do Thi Thanh Huong, Tobias Wang, Nguyen Thanh Phuong, Mark Bayley (2011) Hypoxia tolerance and partitioning of bimodal respiration in the striped catfish (Pangasianodon hypophthalmus). Comparative Biochemistry and Physiology Part A 158(2), pp. 207-214.
2. Nguyen Huong Thuy, Lam Anh Tien, Phuong Nguyen Tuyet, Do Thi Thanh Huong, Nguyen Van Cong, Mark Bayley, Tobias Wang, Sjannie Lefevre (2010) Critical oxygen tension increases during digestion in the perch Perca fluviatilis. Journal of Fish Biology 76, pp. 1025-1031.
1. Tobias Wang, Sjannie Lefevre, Do Thi Thanh Huong, Nguyen Van Cong, Mark Bayley (2009) Impact of hypoxia on growth and digestion. In: Fish Physiology vol. 27 Hypoxia (eds. J.G. Richards, A. P. Farrell, C. J. Brauner), pp. 363-397. Academic Press / Elsevier.
- Lefevre, Sjannie; McKenzie, David J. & Nilsson, Göran E. (2017). Models projecting the fate of fish populations under climate change need to be based on valid physiological mechanisms. Global Change Biology. ISSN 1354-1013. 23(19), s 3449- 3459 . doi: 10.1111/gcb.13652
- Lefevre, Sjannie; Stecyk, Jonathan A. W.; Torp, May-Kristin; Løvold, Lisa Yuen; Sørensen, Christina; Johansen, Ida Beitnes; Stensløkken, Kåre-Olav; Couturier, Christine; Sloman, Katherine A. & Nilsson, Göran Erik (2017). Re-oxygenation after anoxia induces brain cell death and memory loss in the anoxia-tolerant crucian carp. Journal of Experimental Biology. ISSN 0022-0949. 220, s 3883- 3895 . doi: 10.1242/jeb.165118
- Lefevre, Sjannie (2016). Are global warming and ocean acidification conspiring against marine ectotherms? Are meta-analysis of the respiratory effects of elevated temperature, high CO2, and their interaction. Conservation Physiology. ISSN 2051-1434. 4(1) . doi: 10.1093/conphys/cow009
- Lefevre, Sjannie; Bayley, Mark & Mckenzie, David J. (2016). Measuring oxygen uptake in fishes with bimodal respiration. Journal of Fish Biology. ISSN 0022-1112. 88(1), s 206- 231 . doi: 10.1111/jfb.12698
- Mckenzie, David J.; Axelsson, Michael; Chabot, Denis; Claireaux, Guy; Cooke, Steven J.; Corner, Richard A.; De Boeck, Gudrun; Domenici, Paolo; Guerreiro, Pedro M.; Hamer, Bojan; Jørgensen, Christian; Killen, Shaun S.; Lefevre, Sjannie; Marras, Stefano; Michaelidis, Basil; Nilsson, Göran Erik; Peck, Myron A.; Perez-Ruzafa, Angel; Rijnsdorp, Adriaan D.; Shiels, Holly A.; Steffensen, John F.; Svendsen, Jon C.; Svendsen, Morten B. S.; Teal, Lorna R.; van der Meer, Jaap; Wang, Tobias; Wilson, Jonathan M.; Wilson, Rod W. & Metcalfe, Julian D. (2016). Conservation physiology of marine fishes: state of the art and prospects for policy. Conservation Physiology. ISSN 2051-1434. 4(1) . doi: 10.1093/conphys/cow046
- Nilsson, Göran Erik & Lefevre, Sjannie (2016). Physiological challenges to fishes in a warmer and acidified future. Physiology. ISSN 1548-9213. 31(6), s 409- 417 . doi: 10.1152/physiol.00055.2015
- Regan, Matthew D.; Turko, Andy J.; Heras, Joseph; Andersen, Mads Kuhlmann; Lefevre, Sjannie; Wang, Tobias; Bayley, Mark; Brauner, Colin J.; Huong, Do Thi Thanh; Phuong, Nguyen Thanh & Nilsson, Göran Erik (2016). Ambient CO2, fish behaviour and altered GABAergic neurotransmission: Exploring the mechanism of CO2-altered behaviour by taking a hypercapnia dweller down to low CO2 levels. Journal of Experimental Biology. ISSN 0022-0949. 219(1), s 109- 118 . doi: 10.1242/jeb.131375
- Lefevre, Sjannie; Findorf, Inge; Bayley, Mark; Huong, Do Thi Thanh & Wang, Tobias (2015). Increased temperature tolerance of the air-breathing Asian swamp eel Monopterus albus after high-temperature acclimation is not explained by improved cardiorespiratory performance. Journal of Fish Biology. ISSN 0022-1112. . doi: 10.1111/jfb.12696
- Lefevre, Sjannie; Watson, Sue-Ann; Munday, Philip L. & Nilsson, Göran Erik (2015). Will jumping snails prevail? Influence of near-future CO2, temperature and hypoxia on respiratory performance in the tropical conch Gibberulus gibberulus gibbosus. Journal of Experimental Biology. ISSN 0022-0949. 218(19), s 2991- 3001 . doi: 10.1242/jeb.120717
- Cook, D.G.; Brown, Eric Joel; Lefevre, Sjannie; Domenici, Paolo & Fleng Steffensen, John (2014). The response of striped surfperch embiotoca lateralis to progressive hypoxia: Swimming activity, shoal structure, and estimated metabolic expenditure. Journal of Experimental Marine Biology and Ecology. ISSN 0022-0981. 460, s 162- 169 . doi: 10.1016/j.jembe.2014.07.002
- Lefevre, Sjannie; Damsgaard, Christian; Pascale, Desirae R.; Nilsson, Göran Erik & Stecyk, Jonathan Anthony William (2014). Air breathing in the Arctic: influence of temperature, hypoxia, activity and restricted air access on respiratory physiology of the Alaska blackfish Dallia pectoralis. Journal of Experimental Biology. ISSN 0022-0949. 217(24), s 4387- 4398 . doi: 10.1242/jeb.105023
- Lefevre, Sjannie; Domenici, Paolo & Mckenzie, David J. (2014). Swimming in air-breathing fishes. Journal of Fish Biology. ISSN 0022-1112. 84(3), s 661- 681 . doi: 10.1111/jfb.12308
- Wang, Tobias; Lefevre, Sjannie; Iversen, Nina K.; Findorf, Inge; Buchanan, Rasmus & Mckenzie, David J. (2014). Anaemia only causes a small reduction in the upper critical temperature of sea bass: Is oxygen delivery the limiting factor for tolerance of acute warming in fishes?. Journal of Experimental Biology. ISSN 0022-0949. 217(24), s 4275- 4278 . doi: 10.1242/jeb.104166
- Lefevre, Sjannie; Wang, Tobias; Huong, Do Thi Thanh; Phuong, Nguyen Thanh & Bayley, Mark (2013). Partitioning of oxygen uptake and cost of surfacing during swimming in the air-breathing catfish Pangasianodon hypophthalmus. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. ISSN 0174-1578. 183, s 215- 221 . doi: 10.1007/s00360-012-0701-8
- Watson, Sue; Lefevre, Sjannie; McCormick, Mark I.; Domenici, Paolo; Nilsson, Göran Erik & Munday, Philip L. (2013). Marine mollusc predator-escape behaviour altered by near-future carbon dioxide levels. Proceedings of the Royal Society of London. Biological Sciences. ISSN 0962-8452. 281(1774) . doi: 10.1098/rspb.2013.2377
- Lefevre, Sjannie; McKenzie, David J. & Nilsson, Göran Erik (2017). In modelling effects of global warming, invalid assumptions lead to unrealistic projections. Global Change Biology. ISSN 1354-1013. . doi: 10.1111/gcb.13978
- Lefevre, Sjannie (2016). Are respiratory effects of global warming and ocean acidification explained by a unifying OCLTT concept?.
- Lefevre, Sjannie (2016). The transcriptomic response of crucian carp to anoxia and re-oxygenation.
- Lefevre, Sjannie (2015). Snails in the fast-lane: Physiology and Climate Change perspectives. NBS-nytt. ISSN 0801-3535. 39(4), s 20- 21
- Lefevre, Sjannie & Nilsson, Göran E. (2015). Temperature acclimation in jumping snails (Gibberulus gibberulus) reduces heart rate, but not oxygen uptake, and only marginally improves heat tolerance.
- Lefevre, Sjannie; Bayley, Mark; Mckenzie, David J. & Craig, John F. (2014). Air-breathing fishes. Journal of Fish Biology. ISSN 0022-1112. 84(3), s 547- 553 . doi: 10.1111/jfb.12349
- Lefevre, Sjannie; Stecyk, Jonathan A. W.; Torp, May-Kristin & Nilsson, Göran Erik (2014). HOW TOLERANT IS AN ANOXIA-TOLERANT VERTEBRATE?. Show summary
- Lefevre, Sjannie; Watson, Sue-Ann; Munday, Philip L. & Nilsson, Göran Erik (2014). Golbal warming: Will jumping snails prevail?.