Nettsider med emneord «Evolutionary genomics»

Eukaryotic DNA is folded into a three-dimensional (3D) structure inside the nucleus of the cell. Newly developed technologies, such as the Hi-C method [1], have made it possible to probe this 3D structure, giving rise to large amounts of data concerning the spatial arrangement of DNA. In order to get a rendering of the shape and positions of all the chromosomes, bioinformatics algorithms are used.

The figure below shows an example of a 3D model of the human genome, generated from a bioinformatics software called Chrom3D, developed by the supervisor of the project [2].